The efficacy of herbal medicines in clinical models: The case of jambolan

Journal of Ethnopharmacology

Volumn 108, Issue 1, 2006, Pages 16-19

  Teixeira, Claudio Coimbra ^a   Fuchs, Flávio Danni ^b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Diabetes mellitus; Herbal medicines; Jambolan; Syzygium cumini

Indexed keywords

ANTIDIABETIC AGENT; GLIBENCLAMIDE; GLUCOSE; PLACEBO; PLANT EXTRACT; SYGYZIUM CUMINI EXTRACT; SYZYGIUM JAMBOS EXTRACT; UNCLASSIFIED DRUG;

ANTIHYPERGLYCEMIC ACTIVITY; ARTICLE; CLINICAL TRIAL; DIABETES MELLITUS; DRUG ACTIVITY; DRUG EFFICACY; GLUCOSE BLOOD LEVEL; HERBAL MEDICINE; HUMAN; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; SYZYGIUM CUMINI; SYZYGIUM JAMBOS;

SYZYGIUM CUMINI; SYZYGIUM JAMBOS;

EID: 33749359224     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.07.032     Document Type: Note

References (34)

1. Achrekar S., Kaklij G.S., Pote M.S., and Kelkar S.M. Hypoglycemic activity of Eugenia jambolana and Ficus bengalensis: mechanism of action. In Vivo 5 (1991) 143-147
2. Bailey C.J. Biguanides and NIDDM. Diabetes Care 15 (1992) 755-772
3. Bansal R., Ahmad N., and Kidwai R. Effects of administration of Eugenia jambolana seeds and chloropropramide on blood glucose level and pancreatic cathepsin B in rat. Indian Journal of Biochemistry and Biophysics 18 (1981) 377
4. Chivan-Nia P., and Ratsimamanga A.R. Régression de la cataracte et de l'hyperglycémie chez le rat des sables (Psammomys obesus) diabétique ayant reçu un extrait de Eugenia jambolana (Lamarck). Comptes Rendus de l'Academie des Sciences Paris 274 (1972) 254-257
5. Davis S.N., and Granner D.K. Insulin, oral hypoglymemic agents, and the pharmacology of the endocrine pancreas. In: Hardman J.G., Limbird L.E., and Gilman A.G. (Eds). Goodman & Gilman's The Pharmacological Basis of Therapeutics. 10th ed. (2001) 1679-1714
6. Flores R.L., et al. Valoracion de medicamentos homeopaticos y alopaticos en el tratamiento de ratas com diabetes melittus inducida por aloxana. La Homeopatia de Mexico 521 (1998) 10-20
7. Fuchs F.D., Paoli C.L., Hassegawa C.Y., Ferreira E., Netto M.S., and Rosito G.A. O chá de chuchu (Sechium edule) no tratamento da hipertensão: evidência etnofarmacológica de largo emprego em Porto Alegre, RS. Proc. X Simpósio de Plantas Medicinais do Brasil. São Paulo (1988)
8. Giri J., Sakthidevi T.K., and Dushyanthy N. Effect of jamun seed extract on alloxan induced diabetes in rats. Journal of Diabetic Association of India 25 (1985) 115-119
9. Grover J.K., Vats V., and Rathi S.S. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. Journal of Ethnopharmacology 73 (2000) 461-470
10. Kedar P., and Chakrabarti C.H. Effects of jambolan seed treatment on blood sugar, lipids and urea in streptozotocin induced diabetes in rabbits. Indian Journal of Physiology and Pharmacology 27 (1983) 135-140
11. Malone M.H. The pharmacological evaluation of natural products-general and specific approaches to screening ethnopharmaceuticals. Journal of Ethnopharmacology 8 (1983) 127-147
12. Mazzanti C.M., Schossler D.R., Filappi A., Prestes D., Balz D., Miron V., Morsch A., Schetinger M.R.C., Morsch V.M., and Cecim M. Extrato da casca de Syzygium cumini no controle da glicemia e estresse oxidativo de ratos normais e diabéticos. Ciência Rural 33 (2003) 1061-1065
13. Nair R.B., and Santhakumari G. Anti-diabetic activity of the seed kernel of Syzygium cumini Linn. Ancient Science of Life 6 (1986) 80-84
14. Nande C.V., Kale P.M., Wagh S.Y., Antarkar D.S., and Vaidya A.B. Effect of jambu fruit pulp (Eugenia jambolana Lam.) on blood sugar levels in healthy volunteers and diabetics. Journal of Research in Ayurveda and Siddha 4 (1981) 01-05
15. Oliveira A.C.P., Endringer D.C., Amorim L.A.S., Brandao M.G.L., and Coelho M.M. Effect of the extracts and fractions of Baccharis trimera and Syzygium cumini on glycaemia of diabetic and non-diabetic mice. Journal of Ethnopharmacology 102 (2005) 465-469
16. Pepato M.T., Folgado V.B.B., Kettelhut I.C., and Brunetti I.L. Lack of antidiabetic effect of a Eugenia jambolana leaf decoction on rat streptozotocin diabetes. Brazilian Journal of Medical and Biological Research 34 (2001) 389-395
17. Prince P.S., Menon V.P., and Pari L. Hypoglycaemic activity of Syzigium cumini seeds: effect on lip peroxidation in alloxan diabetic rats. Journal of Ethnopharmacology 61 (1998) 1-7
18. Ratsimamanga A.R., et al. Nouvelle contribution à l'étude de l'action d'un principe hypoglycémianty mis en évidence dans l'écorce jeune de Eugenia jambolana (Myrtacées) sur l'hyperglycémie provoquée du lapin normal et poursuite de sa purification. Comptes Rendus de l'Academie des Sciences Paris 227 (1973) 2219-2222
19. Sepaha G.C., and Bose S.N. Clinical observations on the antidiabetic properties of Pterocarpus marsupium and Eugenia jambolana. Journal of the Indian Medical Association 27 (1956) 388-391
20. Shrotri D.S., Kelkar M., Deshmukh V.K., and Aiman R. Investigation of the hypoglycemic properties of Vinca rosea, Cassia auriculata and Eugenia Jambolana. The Indian Journal of Medical Research 51 (1963) 464-467
21. Sigogneau-Jagodzinski M., Bilbal-Prot P., Chanez M., Boiteau P., and Ratsimamanga A.R. Contribuition à l'étude de l'activité hypoglycémiante et antidiabétique d'un principe extrait du Rotra de Magadascar (Eugenia jambolana Lamarck). Comptes Rendus de l'Academie des Sciences Paris 264 (1967) 1119-1123
22. Soares J.C. Níveis glicêmicos e de colesterol em ratos com Diabetes melittus aloxano induzido, tratados com infusão de Bauhinia candicans ou Syzygium jambolanum. Ciência Rural 30 (2000) 113-118
23. Srivastava Y., Venkatakrishna-Bhatt H., Gupta O.P., and Gupta P.S. Hypoglycemia induced by Syzygium cumini Linn. seeds in diabetes mellitus. Asian Medical Journal 26 (1983) 489-491
24. Teixeira C.C., Fuchs F.D., Blotta R.M., Costa A.P., Müssnich D.G., and Ranquetat G.G. Plants employed in the treatment of diabetes mellitus: results of an ethnopharmacological survey in Porto Alegre, Brazil. Fitoterapia 63 (1992) 320-322
25. Teixeira C.C., Fuchs F.D., Blotta R.M., Knijnik J., Delgado I., Netto M., Ferreira E., Costa A.P., Müssnich D.G., Ranquetat G.G., and Gastaldo G.J. Effect of tea prepared from leaves of Syzygium jambos on glucose tolerance in nondiabetes subjects. Diabetes Care 13 (1990) 907-908
26. Teixeira C.C., Fuchs F.D., Weinert L.S., and Esteves J.F. The efficacy of folk medicines in the management of type 2 diabetes mellitus: results of a randomized controlled trial of Syzygium cumini (L.) Skeels. Journal of Clinical Pharmacy and Therapeutics 31 (2006) 1-5
27. Teixeira C.C., Knijnik J., Pereira M.V., and Fuchs F.D. The effect of tea prepare from leaves of "jambolão" (Syzygium cumini) on the blood glucose levels of normal rats: an exploratory study. Proceedings on Brazilian-Sino Symposium on Chemistry and Pharmacology of Natural Products. Rio de Janeiro, Fundação Oswaldo Cruz (1989) 191
28. Teixeira C.C., Pinto L.P., Kessler F.H.P., Knijnik L., Pinto C.P., Gastaldo G.J., and Fuchs F.D. The effect of Sygyzium cumini (L.) Skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin-induced diabetes mellitus. Journal of Ethnopharmacology 56 (1997) 209-213
29. Teixeira C.C., Rava C.A., Silva P.M., Melchior R., Argenta R., Anselmi F., Almeida C.R.C., and Fuchs F.D. Absence of antihyperglycemic effect of jambolan in experimental and clinical models. Journal of Ethnopharmacology 71 (2000) 343-347
30. Teixeira C.C., Weinert L.S., Barbosa D.C., Ricken C., Esteves J.F., and Fucks F.D. Syzygium cumini (L.) Skeels in the treatment of type 2 diabetes. Results of a randomized, double-blind, double-dummy, controlled trial. Diabetes Care 27 (2004) 3019-3020
31. Villasenor I.M., and Lamadrid M.R.A. Comparative anti-hyperglycemic potentials of medicinal plants. Journal of Ethnopharmacology 104 (2006) 129-131
32. Wannmacher L., Fuchs F.D., Paoli C.L., Fillmann H.S., Gianlupi A., Neto J.F.L., and Hassegawa C.Y. Plants employed in the treatment of anxiety and insomnia: II. Effect of infusions of Aloysia triphylia, on experimental anxiety in normal volunteers. Fitoterapia 61 (1990) 449-453
33. Wannmacher L., Fuchs F.D., Paoli C.L., Gianlupi A., Fillmann H.S., Hassegawa C.Y., Ribeiro A.M.S., Muller A.S., Lança E., Marques A., and Guimarães F.S. Plants employed in the treatment of anxiety and insomnia: I. An ethnopharmacological survey in Porto Alegre, Brasil. Fitoterapia 61 (1990) 445-448
34. Zanoello A.M., Melazzo-Mazzanti C., Gindri J.K., Filappi A., Prestes D., and Cecim M. Efeito protetor do Syzygium cumini contra diabetes mellitus induzido por aloxano em ratos. Acta Farmacológica Bonaerense 21 (2002) 31-36