Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 1, 2012, Pages 52-60

  Kobayashi, Shoko ^a   Nagai, Toshitada ^b   Konishi, Yutaka ^c   Tanabe, Soichi ^d   Morimoto, Kaori ^b   Ogihara, Takuo ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c Kirin Company   (Japan)

^d HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Caco 2; flavanone; PAMPA; pH partition hypothesis

Indexed keywords

AGLYCONE; ERIODICTYOL; FLAVANONE; HESPERETIN; HOMOERIODICTYOL; KETOPROFEN; NARINGENIN; PARACETAMOL; PHENAZONE; SAKURANETIN; UNCLASSIFIED DRUG;

ACTIVE TRANSPORT; ARTICLE; ARTIFICIAL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; CONTROLLED STUDY; DIFFUSION; DRUG ABSORPTION; DRUG PENETRATION; DRUG STRUCTURE; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VITRO STUDY; PASSIVE TRANSPORT; PH MEASUREMENT; PHYSICAL CHEMISTRY; TEMPERATURE SENSITIVITY; TRANSPORT KINETICS;

BIOLOGICAL TRANSPORT, ACTIVE; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; FLAVANONES; HUMANS; HYDROGEN-ION CONCENTRATION; MEMBRANES, ARTIFICIAL; MODELS, THEORETICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS;

EID: 83555164706     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2011.01374.x     Document Type: Article

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