-
1
-
-
0035805255
-
Integrated genomic and proteomic analyses of a systematically perturbed metabolic network
-
Ideker T, Thorsson V, Ranish JA, Christmas R, Buhler J, et al. (2001) Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science 292: 929-934.
-
(2001)
Science
, vol.292
, pp. 929-934
-
-
Ideker, T.1
Thorsson, V.2
Ranish, J.A.3
Christmas, R.4
Buhler, J.5
-
2
-
-
0036500993
-
Systems biology: a brief overview
-
Kitano H, Systems biology: a brief overview Science 295: 1662-1664, and Kitano, H (2002) Computational systems biology. Nature 420:206-210.
-
Science
, vol.295
, pp. 1662-1664
-
-
Kitano, H.1
-
3
-
-
0037079054
-
Computational systems biology
-
Kitano, H (2002) Computational systems biology. Nature 420:206-210.
-
(2002)
Nature
, vol.420
, pp. 206-210
-
-
Kitano, H.1
-
4
-
-
18044365052
-
Systems Biology-an interdisciplinary approach
-
Friboulet A, Thomas D, (2005) Systems Biology-an interdisciplinary approach. BiosensBioelectron 20: 2404-2407.
-
(2005)
BiosensBioelectron
, vol.20
, pp. 2404-2407
-
-
Friboulet, A.1
Thomas, D.2
-
5
-
-
0037079015
-
Computational approaches to cellular rhythms
-
Goldbeter A, (2002) Computational approaches to cellular rhythms. Nature 420: 238-245.
-
(2002)
Nature
, vol.420
, pp. 238-245
-
-
Goldbeter, A.1
-
6
-
-
15844387127
-
Candidate metabolic network states in human mitochondria. Impact of diabetes, ischemia, and diet
-
Thiele I, Price ND, Vo TD, Palsson BO, (2005) Candidate metabolic network states in human mitochondria. Impact of diabetes, ischemia, and diet. J BiolChem 280: 11683-11695.
-
(2005)
J BiolChem
, vol.280
, pp. 11683-11695
-
-
Thiele, I.1
Price, N.D.2
Vo, T.D.3
Palsson, B.O.4
-
7
-
-
15944383395
-
Dose-response modeling in reproductive toxicology in the systems biology era
-
Andersen ME, Thomas RS, Gaido KW, Conolly RB, (2005) Dose-response modeling in reproductive toxicology in the systems biology era. ReprodToxicol 19: 327-337.
-
(2005)
ReprodToxicol
, vol.19
, pp. 327-337
-
-
Andersen, M.E.1
Thomas, R.S.2
Gaido, K.W.3
Conolly, R.B.4
-
8
-
-
0032194959
-
Effects of GR203040, an NK1 antagonist, on radiation- and cisplatin-induced tissue damage in the ferret
-
Alfieri AB, Gardner CJ, (1998) Effects of GR203040, an NK1 antagonist, on radiation- and cisplatin-induced tissue damage in the ferret. GenPharmacol 31: 741-746.
-
(1998)
GenPharmacol
, vol.31
, pp. 741-746
-
-
Alfieri, A.B.1
Gardner, C.J.2
-
9
-
-
3042615963
-
Systems level insights into the stress response to UV radiation in the halophilic archaeon Halobacterium NRC-1
-
Baliga NS, Bjork SJ, Bonneau R, Pan M, Iloanusi C, et al. (2004) Systems level insights into the stress response to UV radiation in the halophilic archaeon Halobacterium NRC-1. Genome Res 14: 1025-1035.
-
(2004)
Genome Res
, vol.14
, pp. 1025-1035
-
-
Baliga, N.S.1
Bjork, S.J.2
Bonneau, R.3
Pan, M.4
Iloanusi, C.5
-
10
-
-
33646092543
-
Specific growth rate determines the sensitivity of Escherichia coli to thermal, UVA, and solar disinfection
-
Berney M, Weilenmann HU, Ihssen J, Bassin C, Egli T, (2006) Specific growth rate determines the sensitivity of Escherichia coli to thermal, UVA, and solar disinfection. Appl Environ Microbiol 72: 2586-2593.
-
(2006)
Appl Environ Microbiol
, vol.72
, pp. 2586-2593
-
-
Berney, M.1
Weilenmann, H.U.2
Ihssen, J.3
Bassin, C.4
Egli, T.5
-
11
-
-
33646088615
-
Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae
-
Cline SD, Hanawalt PC, (2006) Topoisomerase deficiencies subtly enhance global genomic repair of ultraviolet-induced DNA damage in Saccharomyces cerevisiae. DNA Repair (Amst) 5: 611-617.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 611-617
-
-
Cline, S.D.1
Hanawalt, P.C.2
-
12
-
-
0023852747
-
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line
-
Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, et al. (1988) Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106: 761-771.
-
(1988)
J Cell Biol
, vol.106
, pp. 761-771
-
-
Boukamp, P.1
Petrussevska, R.T.2
Breitkreutz, D.3
Hornung, J.4
Markham, A.5
-
13
-
-
0036900895
-
Fundamentals of experimental design for cDNA microarrays
-
Churchill GA, (2002) Fundamentals of experimental design for cDNA microarrays. Nat Genet 32 Suppl pp. 490-495.
-
(2002)
Nat Genet 32 Suppl
, pp. 490-495
-
-
Churchill, G.A.1
-
14
-
-
0035032570
-
Statistical design and the analysis of gene expression microarray data
-
Kerr MK, Churchill GA, (2001) Statistical design and the analysis of gene expression microarray data. Genet Res 77: 123-128.
-
(2001)
Genet Res
, vol.77
, pp. 123-128
-
-
Kerr, M.K.1
Churchill, G.A.2
-
15
-
-
0036319960
-
Design issues for cDNA microarray experiments
-
Yang YH, Speed T, (2002) Design issues for cDNA microarray experiments. Nat Rev Genet 3: 579-588.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 579-588
-
-
Yang, Y.H.1
Speed, T.2
-
17
-
-
0037079054
-
Computational systems biology
-
Kitano H, (2002) Computational systems biology. Nature 420: 206-210.
-
(2002)
Nature
, vol.420
, pp. 206-210
-
-
Kitano, H.1
-
18
-
-
3843073212
-
Modeling epithelial cell homeostasis: assessing recovery and control mechanisms
-
Weinstein AM, (2004) Modeling epithelial cell homeostasis: assessing recovery and control mechanisms. Bull Math Biol 66: 1201-1240.
-
(2004)
Bull Math Biol
, vol.66
, pp. 1201-1240
-
-
Weinstein, A.M.1
-
19
-
-
0031963866
-
Activation of the cyclic AMP pathway by alpha-melanotropin mediates the response of human melanocytes to ultraviolet B radiation
-
Im S, Moro O, Peng F, Medrano EE, Cornelius J, et al. (1998) Activation of the cyclic AMP pathway by alpha-melanotropin mediates the response of human melanocytes to ultraviolet B radiation. Cancer Res 58: 47-54.
-
(1998)
Cancer Res
, vol.58
, pp. 47-54
-
-
Im, S.1
Moro, O.2
Peng, F.3
Medrano, E.E.4
Cornelius, J.5
-
20
-
-
0035515358
-
Rays and arrays: the transcriptional program in the response of human epidermal keratinocytes to UVB illumination
-
Li D, Turi TG, Schuck A, Freedberg IM, Khitrov G, et al. (2001) Rays and arrays: the transcriptional program in the response of human epidermal keratinocytes to UVB illumination. FASEB J 15: 2533-2535.
-
(2001)
FASEB J
, vol.15
, pp. 2533-2535
-
-
Li, D.1
Turi, T.G.2
Schuck, A.3
Freedberg, I.M.4
Khitrov, G.5
-
21
-
-
0027363075
-
Hyperthermia induces resistance to ultraviolet light B in primary and immortalized epidermal keratinocytes
-
Maytin EV, Murphy LA, Merrill MA, (1993) Hyperthermia induces resistance to ultraviolet light B in primary and immortalized epidermal keratinocytes. Cancer Res 53: 4952-4959.
-
(1993)
Cancer Res
, vol.53
, pp. 4952-4959
-
-
Maytin, E.V.1
Murphy, L.A.2
Merrill, M.A.3
-
22
-
-
0037022571
-
Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays
-
Sesto A, Navarro M, Burslem F, Jorcano JL, (2002) Analysis of the ultraviolet B response in primary human keratinocytes using oligonucleotide microarrays. Proc Natl Acad Sci U S A 99: 2965-2970.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2965-2970
-
-
Sesto, A.1
Navarro, M.2
Burslem, F.3
Jorcano, J.L.4
-
23
-
-
33745220278
-
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
-
Newman JR, Ghaemmaghami S, Ihmels J, Breslow DK, Noble M, et al. (2006) Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise. Nature 441: 840-846.
-
(2006)
Nature
, vol.441
, pp. 840-846
-
-
Newman, J.R.1
Ghaemmaghami, S.2
Ihmels, J.3
Breslow, D.K.4
Noble, M.5
-
24
-
-
25444468618
-
Noise in gene expression: origins, consequences, and control
-
Raser JM, O'Shea EK, (2005) Noise in gene expression: origins, consequences, and control. Science 309: 2010-2013.
-
(2005)
Science
, vol.309
, pp. 2010-2013
-
-
Raser, J.M.1
O'Shea, E.K.2
-
25
-
-
0030699475
-
Yeast microarrays for genome wide parallel genetic and gene expression analysis
-
Lashkari DA, DeRisi JL, McCusker JH, Namath AF, Gentile C, et al. (1997) Yeast microarrays for genome wide parallel genetic and gene expression analysis. Proc Natl Acad Sci U S A 94: 13057-13062.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13057-13062
-
-
Lashkari, D.A.1
DeRisi, J.L.2
McCusker, J.H.3
Namath, A.F.4
Gentile, C.5
-
26
-
-
0034927555
-
Analysis of variance for gene expression microarray data
-
Kerr MK, Martin M, Churchill GA, (2000) Analysis of variance for gene expression microarray data. J Comput Biol 7: 819-837.
-
(2000)
J Comput Biol
, vol.7
, pp. 819-837
-
-
Kerr, M.K.1
Martin, M.2
Churchill, G.A.3
-
27
-
-
1342294092
-
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
-
Yang YH, Dudoit S, Luu P, Lin DM, Peng V, et al. (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Yang, Y.H.1
Dudoit, S.2
Luu, P.3
Lin, D.M.4
Peng, V.5
-
28
-
-
0030748433
-
Mechanism of apoptotic cell death of human gastric carcinoma cells mediated by transforming growth factor beta
-
Ohta S, Yanagihara K, Nagata K, (1997) Mechanism of apoptotic cell death of human gastric carcinoma cells mediated by transforming growth factor beta. Biochem J 324 (Pt 3): 777-782.
-
(1997)
Biochem J
, vol.324
, Issue.Pt 3
, pp. 777-782
-
-
Ohta, S.1
Yanagihara, K.2
Nagata, K.3
-
29
-
-
7244254455
-
The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development
-
Ramos SB, Stumpo DJ, Kennington EA, Phillips RS, Bock CB, et al. (2004) The CCCH tandem zinc-finger protein Zfp36l2 is crucial for female fertility and early embryonic development. Development 131: 4883-4893.
-
(2004)
Development
, vol.131
, pp. 4883-4893
-
-
Ramos, S.B.1
Stumpo, D.J.2
Kennington, E.A.3
Phillips, R.S.4
Bock, C.B.5
-
30
-
-
0035923529
-
Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B
-
Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, et al. (2001) Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B. Proc Natl Acad Sci U S A 98: 13954-13959.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13954-13959
-
-
Tomizawa, Y.1
Sekido, Y.2
Kondo, M.3
Gao, B.4
Yokota, J.5
-
31
-
-
0034609818
-
Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins
-
Lasorella A, Noseda M, Beyna M, Yokota Y, Iavarone A, (2000) Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 407: 592-598.
-
(2000)
Nature
, vol.407
, pp. 592-598
-
-
Lasorella, A.1
Noseda, M.2
Beyna, M.3
Yokota, Y.4
Iavarone, A.5
-
32
-
-
0036423318
-
GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure
-
Maeda T, Hanna AN, Sim AB, Chua PP, Chong MT, et al. (2002) GADD45 regulates G2/M arrest, DNA repair, and cell death in keratinocytes following ultraviolet exposure. J Invest Dermatol 119: 22-26.
-
(2002)
J Invest Dermatol
, vol.119
, pp. 22-26
-
-
Maeda, T.1
Hanna, A.N.2
Sim, A.B.3
Chua, P.P.4
Chong, M.T.5
-
33
-
-
0030050820
-
Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity
-
Matsuda S, Kawamura-Tsuzuku J, Ohsugi M, Yoshida M, Emi M, et al. (1996) Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity. Oncogene 12: 705-713.
-
(1996)
Oncogene
, vol.12
, pp. 705-713
-
-
Matsuda, S.1
Kawamura-Tsuzuku, J.2
Ohsugi, M.3
Yoshida, M.4
Emi, M.5
-
34
-
-
0034640281
-
Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
-
Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, et al. (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
-
(2000)
Science
, vol.288
, pp. 1053-1058
-
-
Oda, E.1
Ohki, R.2
Murasawa, H.3
Nemoto, J.4
Shibue, T.5
-
35
-
-
34249888804
-
GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling
-
Ayroldi E, Zollo O, Bastianelli A, Marchetti C, Agostini M, et al. (2007) GILZ mediates the antiproliferative activity of glucocorticoids by negative regulation of Ras signaling. J Clin Invest 117: 1605-1615.
-
(2007)
J Clin Invest
, vol.117
, pp. 1605-1615
-
-
Ayroldi, E.1
Zollo, O.2
Bastianelli, A.3
Marchetti, C.4
Agostini, M.5
-
36
-
-
38049134281
-
Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival
-
Li H, Ma X, Wang J, Koontz J, Nucci M, et al. (2007) Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival. Proc Natl Acad Sci U S A 104: 20001-20006.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20001-20006
-
-
Li, H.1
Ma, X.2
Wang, J.3
Koontz, J.4
Nucci, M.5
-
37
-
-
0029871919
-
TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure
-
Lesage F, Guillemare E, Fink M, Duprat F, Lazdunski M, et al. (1996) TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure. EMBO J 15: 1004-1011.
-
(1996)
EMBO J
, vol.15
, pp. 1004-1011
-
-
Lesage, F.1
Guillemare, E.2
Fink, M.3
Duprat, F.4
Lazdunski, M.5
-
38
-
-
0029586476
-
Molecular cloning and gene mapping of human basic and acidic calponins
-
Maguchi M, Nishida W, Kohara K, Kuwano A, Kondo I, et al. (1995) Molecular cloning and gene mapping of human basic and acidic calponins. Biochem Biophys Res Commun 217: 238-244.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 238-244
-
-
Maguchi, M.1
Nishida, W.2
Kohara, K.3
Kuwano, A.4
Kondo, I.5
-
39
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
-
Hayashi H, Abdollah S, Qiu Y, Cai J, Xu YY, et al. (1997) The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell 89: 1165-1173.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.Y.5
-
40
-
-
0033529760
-
A vital role for glycosphingolipid synthesis during development and differentiation
-
Yamashita T, Wada R, Sasaki T, Deng C, Bierfreund U, et al. (1999) A vital role for glycosphingolipid synthesis during development and differentiation. Proc Natl Acad Sci U S A 96: 9142-9147.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 9142-9147
-
-
Yamashita, T.1
Wada, R.2
Sasaki, T.3
Deng, C.4
Bierfreund, U.5
-
41
-
-
33846541348
-
MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system
-
Brandt-Bohne U, Keene DR, White FA, Koch M, (2007) MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system. Biochem J 401: 447-457.
-
(2007)
Biochem J
, vol.401
, pp. 447-457
-
-
Brandt-Bohne, U.1
Keene, D.R.2
White, F.A.3
Koch, M.4
-
42
-
-
0031685620
-
TGF-beta signal transduction
-
Massague J, (1998) TGF-beta signal transduction. Annu Rev Biochem 67: 753-791.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753-791
-
-
Massague, J.1
-
43
-
-
0031847217
-
NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells
-
Wolff T, O'Neill RE, Palese P, (1998) NS1-Binding protein (NS1-BP): a novel human protein that interacts with the influenza A virus nonstructural NS1 protein is relocalized in the nuclei of infected cells. J Virol 72: 7170-7180.
-
(1998)
J Virol
, vol.72
, pp. 7170-7180
-
-
Wolff, T.1
O'Neill, R.E.2
Palese, P.3
-
44
-
-
37549049820
-
Regulation of replication fork progression through histone supply and demand
-
Groth A, Corpet A, Cook AJ, Roche D, Bartek J, et al. (2007) Regulation of replication fork progression through histone supply and demand. Science 318: 1928-1931.
-
(2007)
Science
, vol.318
, pp. 1928-1931
-
-
Groth, A.1
Corpet, A.2
Cook, A.J.3
Roche, D.4
Bartek, J.5
-
45
-
-
0030461764
-
Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins
-
Ben-Porath I, Benvenisty N, (1996) Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. Gene 183: 69-75.
-
(1996)
Gene
, vol.183
, pp. 69-75
-
-
Ben-Porath, I.1
Benvenisty, N.2
-
46
-
-
0034635496
-
Cloning and functional identification of a neuronal glutamine transporter
-
Varoqui H, Zhu H, Yao D, Ming H, Erickson JD, (2000) Cloning and functional identification of a neuronal glutamine transporter. J Biol Chem 275: 4049-4054.
-
(2000)
J Biol Chem
, vol.275
, pp. 4049-4054
-
-
Varoqui, H.1
Zhu, H.2
Yao, D.3
Ming, H.4
Erickson, J.D.5
-
47
-
-
0030985459
-
Exportin 1 (Crm1p) is an essential nuclear export factor
-
Stade K, Ford CS, Guthrie C, Weis K, (1997) Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 90: 1041-1050.
-
(1997)
Cell
, vol.90
, pp. 1041-1050
-
-
Stade, K.1
Ford, C.S.2
Guthrie, C.3
Weis, K.4
|