-
1
-
-
23044496716
-
Long-term effectiveness of potent antiretroviral therapy in preventing AIDS and death: A prospective cohort study
-
Sterne JAC, Hernan MA, Ledergerber B, et al. Long-term effectiveness of potent antiretroviral therapy in preventing AIDS and death: a prospective cohort study. Lancet 2005;366:378-84
-
(2005)
Lancet
, vol.366
, pp. 378-84
-
-
Jac, S.1
Hernan, M.A.2
Ledergerber, B.3
-
2
-
-
52749083531
-
On behalf of the BTGWG. British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008
-
Gazzard BG, on behalf of the BTGWG. British HIV Association guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy 2008. HIV Med 2008;9:563-608
-
(2008)
HIV Med
, vol.9
, pp. 563-608
-
-
Gazzard, B.G.1
-
3
-
-
48949097660
-
Antiretroviral Treatment of Adult HIV Infection
-
Hammer SM, Eron JJ, Reiss P, et al. Antiretroviral Treatment of Adult HIV Infection. JAMA 2008;300:555-70
-
(2008)
JAMA
, vol.300
, pp. 555-70
-
-
Hammer, S.M.1
Eron, J.J.2
Reiss, P.3
-
5
-
-
4444227542
-
Pharmacokinetic properties of nucleoside/nucleotide reverse transcriptase inhibitors
-
Piliero PJ. Pharmacokinetic properties of nucleoside/nucleotide reverse transcriptase inhibitors. J Acquir Immune Defic Syndr 2004;37(Suppl 1):S2-S12
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
, Issue.SUPPL. 1
-
-
Piliero, P.J.1
-
6
-
-
0031929218
-
Chemotherapeutic agents for human immunodeficiency virus infection: Mechanism of action, pharmacokinetics, metabolism, and adverse reactions
-
discussion 1
-
Beach JW. Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions. Clin Ther 1998;20:2-25; discussion 1
-
(1998)
Clin Ther
, vol.20
, pp. 2-25
-
-
Beach, J.W.1
-
7
-
-
38349068747
-
Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system
-
Letendre S, Marquie-Beck J, Capparelli E, et al. Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol 2008;65:65-70
-
(2008)
Arch Neurol
, vol.65
, pp. 65-70
-
-
Letendre, S.1
Marquie-Beck, J.2
Capparelli, E.3
-
8
-
-
79952020252
-
Antiretroviral therapy CNS penetration and HIV-1-associated CNS disease
-
Garvey L, Winston A, Walsh J, et al. Antiretroviral therapy CNS penetration and HIV-1-associated CNS disease. Neurology 2011;76:693-700
-
(2011)
Neurology
, vol.76
, pp. 693-700
-
-
Garvey, L.1
Winston, A.2
Walsh, J.3
-
9
-
-
79551604850
-
Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort
-
Smurzynski M, Wu K, Letendre S, et al. Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohort. AIDS 2011;25:357-65
-
(2011)
AIDS
, vol.25
, pp. 357-65
-
-
Smurzynski, M.1
Wu, K.2
Letendre, S.3
-
10
-
-
84855347192
-
-
Bristol-Myers Squibb Co. Princeton NJ 08543 USA: GlaxoSmithKline
-
ZERIT (package insert). Bristol-Myers Squibb Co. Princeton NJ 08543 USA: GlaxoSmithKline; 2009. Available from: http://wwwomsjorg/drugs/ZERITpdf.
-
(2009)
-
-
-
11
-
-
0025766643
-
Low-dose chemotherapy with central nervous system prophylaxis and zidovudine maintenance in AIDS-related lymphoma. A prospective multi-institutional trial
-
Levine AM, Wernz JC, Kaplan L, et al. Low-dose chemotherapy with central nervous system prophylaxis and zidovudine maintenance in AIDS-related lymphoma. A prospective multi-institutional trial. JAMA 1991;266:84-8
-
(1991)
JAMA
, vol.266
, pp. 84-8
-
-
Levine, A.M.1
Wernz, J.C.2
Kaplan, L.3
-
12
-
-
0029035116
-
Zidovudine treatment prolongs survival and decreases virus load in the central nervous system of rhesus macaques infected perinatally with simian immunodeficiency virus
-
Rausch DM, Heyes MP, Murray EA, Eiden LE. Zidovudine treatment prolongs survival and decreases virus load in the central nervous system of rhesus macaques infected perinatally with simian immunodeficiency virus. J Infect Dis 1995;172:59-69
-
(1995)
J Infect Dis
, vol.172
, pp. 59-69
-
-
Rausch, D.M.1
Heyes, M.P.2
Murray, E.A.3
Eiden, L.E.4
-
13
-
-
7244234280
-
Maternal-fetal transfer and amniotic fluid accumulation of nucleoside analogue reverse transcriptase inhibitors in human immunodeficiency virus-infected pregnant women
-
Chappuy H, Treluyer JM, Jullien V, et al. Maternal-fetal transfer and amniotic fluid accumulation of nucleoside analogue reverse transcriptase inhibitors in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother 2004;48:4332-6
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 4332-6
-
-
Chappuy, H.1
Treluyer, J.M.2
Jullien, V.3
-
15
-
-
0028911385
-
Clinical pharmacokinetics of nucleoside antiretroviral agents
-
Dudley MN. Clinical pharmacokinetics of nucleoside antiretroviral agents. J Infect Dis 1995;171(Suppl 2):S99-112
-
(1995)
J Infect Dis
, vol.171
, Issue.SUPPL. 2
-
-
Dudley, M.N.1
-
16
-
-
0025237790
-
Should the dosage of zidovudine be adjusted in HIV-infected patients with impaired renal function?
-
Amantea MA. Should the dosage of zidovudine be adjusted in HIV-infected patients with impaired renal function? Am J Hosp Pharm 1990;47:618-19
-
(1990)
Am J Hosp Pharm
, vol.47
, pp. 618-19
-
-
Ma, A.1
-
17
-
-
0029587137
-
Pharmacokinetics of zidovudine in HIV-infected patients with end-stage renal disease
-
Kimmel PL, Lew SQ, Umana WO, et al. Pharmacokinetics of zidovudine in HIV-infected patients with end-stage renal disease. Blood Purif 1995;13:340-6
-
(1995)
Blood Purif
, vol.13
, pp. 340-6
-
-
Kimmel, P.L.1
Lew, S.Q.2
Umana, W.O.3
-
18
-
-
84855358697
-
-
Bristol-Myers Squibb Co. Princeton, NJ 08543 USA
-
Videx (package insert). Bristol-Myers Squibb Co. Princeton, NJ 08543 USA. Available from: http:// wwwpackageinsertsbmscom/pi/ pi-videx-ecpdf
-
-
-
-
19
-
-
0025763660
-
Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex
-
Knupp CA, Shyu WC, Dolin R, et al. Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex. Clin Pharmacol Ther 1991;49:523-35
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 523-35
-
-
Knupp, C.A.1
Shyu, W.C.2
Dolin, R.3
-
20
-
-
0032480991
-
Comparison of the plasma pharmacokinetics and renal clearance of didanosine during once and twice daily dosing in HIV-1 infected individuals
-
Hoetelmans RM, van Heeswijk RP, Profijt M, et al. Comparison of the plasma pharmacokinetics and renal clearance of didanosine during once and twice daily dosing in HIV-1 infected individuals. AIDS 1998;12:F211-16
-
(1998)
AIDS
, vol.12
-
-
Hoetelmans, R.M.1
Van Heeswijk, R.P.2
Profijt, M.3
-
21
-
-
77950279895
-
Disposition of [1′-14C] Stavudine after oral administration to humans
-
Zhou L, Kaul S, Liu-Kreyche P, et al. Disposition of [1′-14C] Stavudine after oral administration to humans. Drug Metab Dispos 2010;38:655-66
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 655-66
-
-
Zhou, L.1
Kaul, S.2
Liu-Kreyche, P.3
-
22
-
-
10744229088
-
Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients
-
Becher F, Landman R, Mboup S, et al. Monitoring of didanosine and stavudine intracellular trisphosphorylated anabolite concentrations in HIV-infected patients. AIDS 2004;18:181-7
-
(2004)
AIDS
, vol.18
, pp. 181-7
-
-
Becher, F.1
Landman, R.2
Mboup, S.3
-
24
-
-
42549113615
-
Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: A randomized, controlled study
-
McComsey GA, Lo Re V III, ORiordan M, et al. Effect of reducing the dose of stavudine on body composition, bone density, and markers of mitochondrial toxicity in HIV-infected subjects: a randomized, controlled study. Clin Infect Dis 2008;46:1290-6
-
(2008)
Clin Infect Dis
, vol.46
, pp. 1290-6
-
-
McComsey, G.A.1
Lo Re Iii, V.2
Oriordan, M.3
-
25
-
-
0029591139
-
Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine
-
Yuen GJ, Morris DM, Mydlow PK, et al. Pharmacokinetics, absolute bioavailability, and absorption characteristics of lamivudine. J Clin Pharmacol 1995;35:1174-80
-
(1995)
J Clin Pharmacol
, vol.35
, pp. 1174-80
-
-
Yuen, G.J.1
Morris, D.M.2
Mydlow, P.K.3
-
26
-
-
84855348761
-
-
Research Traingle Park, NC:GlaxoSmithKline
-
Epivir (package insert). Research Traingle Park, NC:GlaxoSmithKline;2011. Available from: http://usgskcom/ products/assets/us-epivirpdf
-
(2011)
-
-
-
27
-
-
0031723646
-
Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring
-
Moodley J, Moodley D, Pillay K, et al. Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring. J Infect Dis 1998;178:1327-33
-
(1998)
J Infect Dis
, vol.178
, pp. 1327-33
-
-
Moodley, J.1
Moodley, D.2
Pillay, K.3
-
28
-
-
84855358696
-
-
Research Traingle Park, NC:GlaxoSmithKline
-
Retrovir (package insert). Research Traingle Park, NC: GlaxoSmithKline;2011. Available from: http://usgskcom/products/ assets/us-retrovirpdf.
-
(2011)
-
-
-
30
-
-
0001024860
-
The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1
-
Moore KH, Barrett JE, Shaw S, et al. The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1. AIDS 1999;13:2239-50
-
(1999)
AIDS
, vol.13
, pp. 2239-50
-
-
Moore, K.H.1
Barrett, J.E.2
Shaw, S.3
-
32
-
-
0032766290
-
Abacavir: Absolute bioavailability, bioequivalence of three oral formulations, and effect of food
-
Chittick GE, Gillotin C, McDowell JA, et al. Abacavir: absolute bioavailability, bioequivalence of three oral formulations, and effect of food. Pharmacotherapy 1999;19:932-42
-
(1999)
Pharmacotherapy
, vol.19
, pp. 932-42
-
-
Chittick, G.E.1
Gillotin, C.2
McDowell, J.A.3
-
33
-
-
84855358694
-
-
Research Traingle Park, NC: GlaxoSmithKline
-
Ziagen (package insert). Research Traingle Park, NC: GlaxoSmithKline; 2009. Available from: http://usgskcom/products/ assets/us-ziagenpdf.
-
(2009)
-
-
-
34
-
-
33645391801
-
Impact of pregnancy on abacavir pharmacokinetics
-
Best BM, Mirochnick M, Capparelli EV, et al. Impact of pregnancy on abacavir pharmacokinetics. AIDS 2006;20:553-60
-
(2006)
AIDS
, vol.20
, pp. 553-60
-
-
Best, B.M.1
Mirochnick, M.2
Capparelli, E.V.3
-
35
-
-
65649133113
-
Steady-state pharmacokinetics of abacavir in plasma and intracellular carbovir triphosphate following administration of abacavir at 600 milligrams once daily and 300 milligrams twice daily in human immunodeficiency virus-infected subjects
-
Moyle G, Boffito M, Fletcher C, et al. Steady-state pharmacokinetics of abacavir in plasma and intracellular carbovir triphosphate following administration of abacavir at 600 milligrams once daily and 300 milligrams twice daily in human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother 2009;53:1532-8
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1532-8
-
-
Moyle, G.1
Boffito, M.2
Fletcher, C.3
-
36
-
-
0142126681
-
Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections
-
De Clercq E. Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections. Clin Microbiol Rev 2003;16:569-96
-
(2003)
Clin Microbiol Rev
, vol.16
, pp. 569-96
-
-
De Clercq, E.1
-
37
-
-
84855341996
-
-
Foster City, CA: Gilead Sciences, Inc
-
Viread (package insert). Foster City, CA: Gilead Sciences, Inc;2010. Available from: http://wwwgileadcom/pdf/ viread-pipdf
-
(2010)
-
-
-
38
-
-
33645895267
-
The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses
-
Anthonypillai C, Gibbs J, Thomas S. The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses. Cerebrospinal Fluid Res 2006;3:1
-
(2006)
Cerebrospinal Fluid Res
, vol.3
, pp. 1
-
-
Anthonypillai, C.1
Gibbs, J.2
Thomas, S.3
-
39
-
-
17644445089
-
Administration of 9-[2-(Phosphonomethoxy)propyl] adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques
-
Van Rompay KKA, Marthas ML, Lifson JD, et al. Administration of 9-[2-(Phosphonomethoxy)propyl] adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques. AIDS Res Hum Retroviruses 1998;14:761-73
-
(1998)
AIDS Res Hum Retroviruses
, vol.14
, pp. 761-73
-
-
Van Rompay Kka1
Marthas, M.L.2
Lifson, J.D.3
-
40
-
-
22244455094
-
The pharmacology of antiretroviral nucleoside and nucleotide reverse transcriptase inhibitors: Implications for once-daily dosing
-
Back DJ, Burger DM, Flexner CW, Gerber JG. The pharmacology of antiretroviral nucleoside and nucleotide reverse transcriptase inhibitors: implications for once-daily dosing. J Acquir Immune Defic Syndr 2005;39:S1-S23
-
(2005)
J Acquir Immune Defic Syndr
, vol.39
-
-
Back, D.J.1
Burger, D.M.2
Flexner, C.W.3
Gerber, J.G.4
-
41
-
-
84855347191
-
-
Gilead Sciences, Inc
-
Emtriva (package insert). Gilead Sciences, Inc;2008. Available from: http:// wwwgileadcom/pdf/emtriva-pipdf
-
(2008)
-
-
-
42
-
-
0023268502
-
The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
-
Fischl MA, Richman DD, Grieco MH, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987;317:185-91
-
(1987)
N Engl J Med
, vol.317
, pp. 185-91
-
-
Fischl, M.A.1
Richman, D.D.2
Grieco, M.H.3
-
43
-
-
0027155374
-
The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2′,3′-dideoxyinosine and 2prime;,3′- dideoxycytidine confers high-level resistance to the (-) enantiomer of 2′,3′-dideoxy-3′-thiacytidine
-
Gao Q, Gu Z, Parniak MA, et al. The same mutation that encodes low-level human immunodeficiency virus type 1 resistance to 2′,3′- dideoxyinosine and 2prime;,3′-dideoxycytidine confers high-level resistance to the (-) enantiomer of 2′,3′-dideoxy-3′- thiacytidine. Antimicrob Agents Chemother 1993;37:1390-2
-
(1993)
Antimicrob Agents Chemother
, vol.37
, pp. 1390-2
-
-
Gao, Q.1
Gu, Z.2
Parniak, M.A.3
-
44
-
-
0027285372
-
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
-
Tisdale M, Kemp SD, Parry NR, Larder BA. Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc Natl Acad Sci USA 1993;90:5653-6
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 5653-6
-
-
Tisdale, M.1
Kemp, S.D.2
Parry, N.R.3
Larder, B.A.4
-
45
-
-
8944245852
-
Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy
-
Lamivudine European HIV Working Group
-
Staszewski S, Loveday C, Picazo JJ, et al. Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group. JAMA 1996;276:111-17
-
(1996)
JAMA
, vol.276
, pp. 111-17
-
-
Staszewski, S.1
Loveday, C.2
Picazo, J.J.3
-
46
-
-
0025866982
-
Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2′- deoxy-3′-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog
-
Soudeyns H, Yao XI, Gao Q, et al. Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2′- deoxy-3′-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog. Antimicrob Agents Chemother 1991;35:1386-90
-
(1991)
Antimicrob Agents Chemother
, vol.35
, pp. 1386-90
-
-
Soudeyns, H.1
Yao, X.I.2
Gao, Q.3
-
47
-
-
8944225025
-
Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy
-
Lamivudine European HIV Working Group
-
Katlama C, Ingrand D, Loveday C, et al. Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. A randomized controlled comparison with zidovudine monotherapy. Lamivudine European HIV Working Group. JAMA 1996;276:118-25
-
(1996)
JAMA
, vol.276
, pp. 118-25
-
-
Katlama, C.1
Ingrand, D.2
Loveday, C.3
-
48
-
-
0034691818
-
Virologic and CD4+ cell responses to new nucleoside regimens: Switching to stavudine or adding lamivudine after prolonged zidovudine treatment of human immunodeficiency virus infection
-
ACTG 302 Study Team. AIDS Clinical Trials Group
-
Katzenstein DA, Hughes M, Albrecht M, et al. Virologic and CD4+ cell responses to new nucleoside regimens: switching to stavudine or adding lamivudine after prolonged zidovudine treatment of human immunodeficiency virus infection. ACTG 302 Study Team. AIDS Clinical Trials Group. AIDS Res Hum Retroviruses 2000;16:1031-7
-
(2000)
AIDS Res Hum Retroviruses
, vol.16
, pp. 1031-7
-
-
Katzenstein, D.A.1
Hughes, M.2
Albrecht, M.3
-
49
-
-
0031058463
-
Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: A meta-analysis of controlled trials
-
Staszewski S, Hill AM, Bartlett J, et al. Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials. AIDS 1997;11:477-83
-
(1997)
AIDS
, vol.11
, pp. 477-83
-
-
Staszewski, S.1
Hill, A.M.2
Bartlett, J.3
-
50
-
-
0345012053
-
Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection
-
Robbins GK, De Gruttola V, Shafer RW, et al. Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection. N Engl J Med 2003;349:2293-303
-
(2003)
N Engl J Med
, vol.349
, pp. 2293-303
-
-
Robbins, G.K.1
De Gruttola, V.2
Shafer, R.W.3
-
51
-
-
0033604038
-
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
-
Brinkman K, Smeitink JA, Romijn JA, Reiss P. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet 1999;354:1112-15
-
(1999)
Lancet
, vol.354
, pp. 1112-15
-
-
Brinkman, K.1
Smeitink, J.A.2
Romijn, J.A.3
Reiss, P.4
-
52
-
-
33749356252
-
Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial
-
Ssali F, Stohr W, Munderi P, et al. Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial. Antivir Ther 2006;11:741-9
-
(2006)
Antivir Ther
, vol.11
, pp. 741-9
-
-
Ssali, F.1
Stohr, W.2
Munderi, P.3
-
53
-
-
78049469747
-
High incidence of zidovudine induced anaemia in HIV infected patients in eastern India
-
Agarwal D, Chakravarty J, Chaube L, et al. High incidence of zidovudine induced anaemia in HIV infected patients in eastern India. Indian J Med Res 2010;132:386-9
-
(2010)
Indian J Med Res
, vol.132
, pp. 386-9
-
-
Agarwal, D.1
Chakravarty, J.2
Chaube, L.3
-
54
-
-
68449101741
-
A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals
-
Fisher M, Moyle GJ, Shahmanesh M, et al. A randomized comparative trial of continued zidovudine/lamivudine or replacement with tenofovir disoproxil fumarate/emtricitabine in efavirenz-treated HIV-1-infected individuals. J Acquir Immune Defic Syndr 2009;51:562-8
-
(2009)
J Acquir Immune Defic Syndr
, vol.51
, pp. 562-8
-
-
Fisher, M.1
Moyle, G.J.2
Shahmanesh, M.3
-
55
-
-
54549094981
-
Switch from zidovudine- to non-zidovudine-containing regimens is associated with modest haematological improvement and no obvious clinical benefit: A substudy of the ANRS 099 ALIZE trial
-
Lafaurie M, Collin F, Bentata M, et al. Switch from zidovudine- to non-zidovudine-containing regimens is associated with modest haematological improvement and no obvious clinical benefit: a substudy of the ANRS 099 ALIZE trial. J Antimicrob Chemother 2008;62:1122-9
-
(2008)
J Antimicrob Chemother
, vol.62
, pp. 1122-9
-
-
Lafaurie, M.1
Collin, F.2
Bentata, M.3
-
56
-
-
66549115865
-
Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT)
-
Arasteh K, Weitner L, Fenske S, et al. Switch from a ZDV/3TC-based regimen to a completely once daily (QD) regimen of emtricitabine/tenofovir DF fixed dose combination plus a third QD agent (SONETT). Eur J Med Res 2009;14:195-9
-
(2009)
Eur J Med Res
, vol.14
, pp. 195-9
-
-
Arasteh, K.1
Weitner, L.2
Fenske, S.3
-
57
-
-
57049172088
-
Development of an optimized dose for coformulation of zidovudine with drugs that select for the K65R mutation using a population pharmacokinetic and enzyme kinetic simulation model
-
Hurwitz SJ, Asif G, Kivel NM, Schinazi RF. Development of an optimized dose for coformulation of zidovudine with drugs that select for the K65R mutation using a population pharmacokinetic and enzyme kinetic simulation model. Antimicrob Agents Chemother 2008;52:4241-50
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 4241-50
-
-
Hurwitz, S.J.1
Asif, G.2
Kivel, N.M.3
Schinazi, R.F.4
-
60
-
-
3042848853
-
Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
-
Gallant JE, Staszewski S, Pozniak AL, et al. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA 2004;292:191-201
-
(2004)
JAMA
, vol.292
, pp. 191-201
-
-
Gallant, J.E.1
Staszewski, S.2
Pozniak, A.L.3
-
61
-
-
30944468562
-
Tenofovir DF. Emtricitabine, and Efavirenz vs. Zidovudine, Lamivudine, and Efavirenz for HIV
-
Gallant JE, DeJesus E, Arribas JR, et al. Tenofovir DF. Emtricitabine, and Efavirenz vs. Zidovudine, Lamivudine, and Efavirenz for HIV. N Engl J Med 2006;354:251-60
-
(2006)
N Engl J Med
, vol.354
, pp. 251-60
-
-
Gallant, J.E.1
Dejesus, E.2
Arribas, J.R.3
-
62
-
-
49649112490
-
Once-daily atazanavir/ ritonavir versus twice-daily lopinavir/ ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study
-
Molina J-M, Andrade-Villanueva J, Echevarria J, et al. Once-daily atazanavir/ ritonavir versus twice-daily lopinavir/ ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study. Lancet 2008;372:646-55
-
(2008)
Lancet
, vol.372
, pp. 646-55
-
-
Molina, J.-M.1
Andrade-Villanueva, J.2
Echevarria, J.3
-
63
-
-
64249163753
-
Gemini: A noninferiority study of Saquinavir/Ritonavir versus Lopinavir/ Ritonavir as initial HIV-1 therapy in adults
-
Walmsley S, Avihingsanon A, Slim J, et al. Gemini: a noninferiority study of Saquinavir/Ritonavir versus Lopinavir/ Ritonavir as initial HIV-1 therapy in adults. J Acquir Immune Defic Syndr 2009;50:367-74
-
(2009)
J Acquir Immune Defic Syndr
, vol.50
, pp. 367-74
-
-
Walmsley, S.1
Avihingsanon, A.2
Slim, J.3
-
64
-
-
33845354174
-
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: Virologic, immunologic, and morphologic changes - A 96-week analysis
-
Pozniak AL, Gallant JE, DeJesus E, et al. Tenofovir disoproxil fumarate, emtricitabine, and efavirenz versus fixed-dose zidovudine/lamivudine and efavirenz in antiretroviral-naive patients: virologic, immunologic, and morphologic changes-a 96-week analysis. J Acquir Immune Defic Syndr 2006;43:535-40
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, pp. 535-40
-
-
Pozniak, A.L.1
Gallant, J.E.2
Dejesus, E.3
-
65
-
-
39049101609
-
Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis
-
Arribas JR, Pozniak AL, Gallant JE, et al. Tenofovir disoproxil fumarate, emtricitabine, and efavirenz compared with zidovudine/lamivudine and efavirenz in treatment-naive patients: 144-week analysis. J Acquir Immune Defic Syndr 2008;47:74-8
-
(2008)
J Acquir Immune Defic Syndr
, vol.47
, pp. 74-8
-
-
Arribas, J.R.1
Pozniak, A.L.2
Gallant, J.E.3
-
66
-
-
68949131185
-
Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel
-
Turner D, Shahar E, Katchman E, et al. Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel. J Med Virol 2009;81:1509-12
-
(2009)
J Med Virol
, vol.81
, pp. 1509-12
-
-
Turner, D.1
Shahar, E.2
Katchman, E.3
-
67
-
-
70349656911
-
Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria
-
Hawkins CA, Chaplin B, Idoko J, et al. Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. J Acquir Immune Defic Syndr 2009;52:228-34
-
(2009)
J Acquir Immune Defic Syndr
, vol.52
, pp. 228-34
-
-
Hawkins, C.A.1
Chaplin, B.2
Idoko, J.3
-
68
-
-
0037076711
-
Tenofovir DF in antiretroviral-experienced patients: Results from a 48-week, randomized, double-blind study
-
Schooley RT, Ruane P, Myers RA, et al. Tenofovir DF in antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study. AIDS 2002;16:1257-63
-
(2002)
AIDS
, vol.16
, pp. 1257-63
-
-
Schooley, R.T.1
Ruane, P.2
Myers, R.A.3
-
69
-
-
1642453729
-
Tenofovir disoproxil fumarate in nucleoside-resistant HIV-1 infection: A randomized trial
-
Squires K, Pozniak AL, Pierone G Jr, et al. Tenofovir disoproxil fumarate in nucleoside-resistant HIV-1 infection: a randomized trial. Ann Intern Med 2003;139:313-20
-
(2003)
Ann Intern Med
, vol.139
, pp. 313-20
-
-
Squires, K.1
Pozniak, A.L.2
Pierone Jr., G.3
-
70
-
-
15044341385
-
Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: Results of the Ziagen Once Daily in Antiretroviral Combination Study
-
Moyle GJ, DeJesus E, Cahn P, et al. Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: results of the Ziagen Once Daily in Antiretroviral Combination Study. J Acquir Immune Defic Syndr 2005;38:417-25
-
(2005)
J Acquir Immune Defic Syndr
, vol.38
, pp. 417-25
-
-
Moyle, G.J.1
Dejesus, E.2
Cahn, P.3
-
71
-
-
73349134686
-
Abacavir-Lamivudine versus Tenofovir-Emtricitabine for Initial HIV-1 Therapy
-
Sax PE, Tierney C, Collier AC, et al. Abacavir-Lamivudine versus Tenofovir-Emtricitabine for Initial HIV-1 Therapy. N Engl J Med 2009;361:2230-40
-
(2009)
N Engl J Med
, vol.361
, pp. 2230-40
-
-
Sax, P.E.1
Tierney, C.2
Collier, A.C.3
-
72
-
-
68649086238
-
Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/ emtricitabine with lopinavir/ritonavir for initial HIV treatment
-
Smith KY, Patel P, Fine D, et al. Randomized, double-blind, placebo-matched, multicenter trial of abacavir/lamivudine or tenofovir/ emtricitabine with lopinavir/ritonavir for initial HIV treatment. AIDS 2009;23:1547-56
-
(2009)
AIDS
, vol.23
, pp. 1547-56
-
-
Smith, K.Y.1
Patel, P.2
Fine, D.3
-
73
-
-
10044236429
-
Renal dysfunction with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy regimens is not observed more frequently: A cohort and case-control study
-
Jones R, Stebbing J, Nelson M, et al. Renal dysfunction with tenofovir disoproxil fumarate-containing highly active antiretroviral therapy regimens is not observed more frequently: a cohort and case-control study. J Acquir Immune Defic Syndr 2004;37:1489-95
-
(2004)
J Acquir Immune Defic Syndr
, vol.37
, pp. 1489-95
-
-
Jones, R.1
Stebbing, J.2
Nelson, M.3
-
74
-
-
33745924378
-
Renal safety of tenofovir disoproxil fumarate in HIV-1 treatment-experienced patients with adverse events related to prior NRTI use: Data from a prospective, observational, multicenter study
-
Moreno S, Domingo P, Palacios R, et al. Renal safety of tenofovir disoproxil fumarate in HIV-1 treatment-experienced patients with adverse events related to prior NRTI use: data from a prospective, observational, multicenter study. J Acquir Immune Defic Syndr 2006;42:385-7
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 385-7
-
-
Moreno, S.1
Domingo, P.2
Palacios, R.3
-
75
-
-
74049090916
-
Impact of tenofovir on renal function in HIV-infected, antiretroviral-naive patients
-
Horberg M, Tang B, Towner W, et al. Impact of tenofovir on renal function in HIV-infected, antiretroviral-naive patients. J Acquir Immune Defic Syndr 2010;53:62-9
-
(2010)
J Acquir Immune Defic Syndr
, vol.53
, pp. 62-9
-
-
Horberg, M.1
Tang, B.2
Towner, W.3
-
76
-
-
83455264215
-
Renal Impairment in Patients Receiving a TDF-based cART Regimen: Impact of TDF Concentration?
-
Boston
-
Poizot-Martin I, Solas C, Allemand J, et al. Renal Impairment in Patients Receiving a TDF-based cART Regimen: Impact of TDF Concentration? CROI; Boston: 2010
-
(2010)
CROI
-
-
Poizot-Martin, I.1
Solas, C.2
Allemand, J.3
-
77
-
-
77950925935
-
Impairment in kidney tubular function in patients receiving tenofovir is associated with higher tenofovir plasma concentrations
-
Rodriguez-Novoa S, Labarga P, DAvolio A, et al. Impairment in kidney tubular function in patients receiving tenofovir is associated with higher tenofovir plasma concentrations. AIDS 2010;24:1064-6
-
(2010)
AIDS
, vol.24
, pp. 1064-6
-
-
Rodriguez-Novoa, S.1
Labarga, P.2
Davolio, A.3
-
79
-
-
77957847133
-
Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir-emtricitabine in HIV-infected adults: 48-week results from the ASSERT study
-
Stellbrink HJ, Orkin C, Arribas JR, et al. Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir-emtricitabine in HIV-infected adults: 48-week results from the ASSERT study. Clin Infect Dis 2010;51:963-72
-
(2010)
Clin Infect Dis
, vol.51
, pp. 963-72
-
-
Stellbrink, H.J.1
Orkin, C.2
Arribas, J.R.3
-
80
-
-
77949874814
-
Tenofovir treatment of primary osteoblasts alters gene expression profiles: Implications for bone mineral density loss
-
Grigsby IF, Pham L, Mansky LM, et al. Tenofovir treatment of primary osteoblasts alters gene expression profiles: implications for bone mineral density loss. Biochem Biophys Res Commun 2010;394:48-53
-
(2010)
Biochem Biophys Res Commun
, vol.394
, pp. 48-53
-
-
Grigsby, I.F.1
Pham, L.2
Mansky, L.M.3
-
81
-
-
79957494036
-
Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a Substudy of ACTG A5202
-
McComsey GA, Kitch D, Daar ES, et al. Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a Substudy of ACTG A5202. J Infect Dis 2011;203:1791-801
-
(2011)
J Infect Dis
, vol.203
, pp. 1791-801
-
-
McComsey, G.A.1
Kitch, D.2
Daar, E.S.3
-
82
-
-
34547229756
-
The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naive HIV-1-infected patients
-
Cassetti I, Madruga JV, Suleiman JM, et al. The safety and efficacy of tenofovir DF in combination with lamivudine and efavirenz through 6 years in antiretroviral-naive HIV-1-infected patients. HIV Clin Trials 2007;8:164-72
-
(2007)
HIV Clin Trials
, vol.8
, pp. 164-72
-
-
Cassetti, I.1
Madruga, J.V.2
Suleiman, J.M.3
-
84
-
-
63149165917
-
Abacavir/3TC vs. tenofovir/ FTC: Interim results from ACTG 5202
-
Albrecht H. Abacavir/3TC vs. tenofovir/ FTC: interim results from ACTG 5202. AIDS Clin Care 2008;20:28
-
(2008)
AIDS Clin Care
, vol.20
, pp. 28
-
-
Albrecht, H.1
-
86
-
-
79959810675
-
HLA-B*5701 genetic screening prior to abacavir prescription in Georgia
-
Dvali N, Chkhartishvili N, Sharvadze L, et al. HLA-B*5701 genetic screening prior to abacavir prescription in Georgia. Georgian Med News 2010;16-20
-
(2010)
Georgian Med News
, pp. 16-20
-
-
Dvali, N.1
Chkhartishvili, N.2
Sharvadze, L.3
-
87
-
-
0037006623
-
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002;359:727-32
-
(2002)
Lancet
, vol.359
, pp. 727-32
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
-
88
-
-
12844254320
-
Updated clinical risk factor analysis of suspected hypersensitivity reactions to abacavir
-
Cutrell AG, Hernandez JE, Fleming JW, et al. Updated clinical risk factor analysis of suspected hypersensitivity reactions to abacavir. Ann Pharmacother 2004;38:2171-2
-
(2004)
Ann Pharmacother
, vol.38
, pp. 2171-2
-
-
Cutrell, A.G.1
Hernandez, J.E.2
Fleming, J.W.3
-
89
-
-
75749085418
-
Prospective epidemiological study of the prevalence of human leukocyte antigen (HLA)-B*5701 in HIV-1-infected UK subjects
-
on behalf of the UKEPIt
-
Orkin C, Sadiq ST, Rice L, Jackson F; on behalf of the UKEPIt. Prospective epidemiological study of the prevalence of human leukocyte antigen (HLA)-B*5701 in HIV-1-infected UK subjects. HIV Med 2010;11:187-92
-
(2010)
HIV Med
, vol.11
, pp. 187-92
-
-
Orkin, C.1
Sadiq, S.T.2
Rice, L.3
Jackson, F.4
-
90
-
-
42649130015
-
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: A multi-cohort collaboration
-
Sabin CA, Worm SW, Weber R, et al. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration. Lancet 2008;371:1417-26
-
(2008)
Lancet
, vol.371
, pp. 1417-26
-
-
Sabin, C.A.1
Worm, S.W.2
Weber, R.3
-
91
-
-
42549131481
-
Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: Role of CD4+ Cell counts and HIV RNA levels during follow-up
-
Lundgren JD, Babiker A, El-Sadr W, et al. Inferior clinical outcome of the CD4+ cell count-guided antiretroviral treatment interruption strategy in the SMART study: role of CD4+ Cell counts and HIV RNA levels during follow-up. J Infect Dis 2008;197:1145-55
-
(2008)
J Infect Dis
, vol.197
, pp. 1145-55
-
-
Lundgren, J.D.1
Babiker, A.2
El-Sadr, W.3
-
92
-
-
67649110188
-
Impact of specific NRTI and PI exposure on the risk of myocardial infarction: A Case-Control Study Nested within FHDH ANRS CO4
-
Montreal Canada
-
Lang S, Mary-Krause M, Cotte L, et al. Impact of specific NRTI and PI exposure on the risk of myocardial infarction: a Case-Control Study Nested within FHDH ANRS CO4. CROI; Montreal, Canada: 2009
-
(2009)
CROI
-
-
Lang, S.1
Mary-Krause, M.2
Cotte, L.3
-
93
-
-
67651167085
-
Risk of myocardial infarction and abacavir therapy: No increased risk across 52 GlaxoSmithKline-sponsored clinical trials in adult subjects
-
Brothers CH, Hernandez JE, Cutrell AG, et al. Risk of myocardial infarction and abacavir therapy: no increased risk across 52 GlaxoSmithKline-sponsored clinical trials in adult subjects. J Acquir Immune Defic Syndr 2009;51:20-8
-
(2009)
J Acquir Immune Defic Syndr
, vol.51
, pp. 20-8
-
-
Ch, B.1
Hernandez, J.E.2
Cutrell, A.G.3
-
94
-
-
79953731529
-
No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: Short and long-term results from ACTG A5001/ALLRT
-
Ribaudo HJ, Benson CA, Zheng Y, et al. No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: short and long-term results from ACTG A5001/ ALLRT. Clin Infect Dis 2011;52:929-40
-
(2011)
Clin Infect Dis
, vol.52
, pp. 929-40
-
-
Ribaudo, H.J.1
Benson, C.A.2
Zheng, Y.3
-
95
-
-
11144357656
-
Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: A randomised open-label trial, the 2NN Study
-
Van Leth F, Phanuphak P, Ruxrungtham K, et al. Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study. Lancet 2004;363:1253-63
-
(2004)
Lancet
, vol.363
, pp. 1253-63
-
-
Van Leth, F.1
Phanuphak, P.2
Ruxrungtham, K.3
-
96
-
-
77955950938
-
Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naive individuals
-
CD008651
-
Spaulding A, Rutherford GW, Siegfried N. Stavudine or zidovudine in three-drug combination therapy for initial treatment of HIV infection in antiretroviral-naive individuals. Cochrane Database Syst Rev 2010;CD008651
-
(2010)
Cochrane Database Syst Rev
-
-
Spaulding, A.1
Rutherford, G.W.2
Siegfried, N.3
-
97
-
-
79953180935
-
Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy
-
Domingo P, Cabeza MC, Pruvost A, et al. Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy. Antimicrob Agents Chemother 2011;55:1428-35
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 1428-35
-
-
Domingo, P.1
Cabeza, M.C.2
Pruvost, A.3
-
98
-
-
44949106506
-
Safety of stavudine in the treatment of HIV infection with a special focus on resource-limited settings
-
Makinson A, Moing VL, Kouanfack C, et al. Safety of stavudine in the treatment of HIV infection with a special focus on resource-limited settings. Expert Opin Drug Saf 2008;7:283-93
-
(2008)
Expert Opin Drug Saf
, vol.7
, pp. 283-93
-
-
Makinson, A.1
Moing, V.L.2
Kouanfack, C.3
-
99
-
-
65749093276
-
Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen
-
Gerschenson M, Kim C, Berzins B, et al. Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen. J Antimicrob Chemother 2009;63:1244-50
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 1244-50
-
-
Gerschenson, M.1
Kim, C.2
Berzins, B.3
-
100
-
-
78650472932
-
HIV treatment guidelines in resource-limited settings: A model-based analysis
-
Scaling up the 2010. World Health Organization
-
Walensky RP, Wood R, Ciaranello AL, et al. Scaling up the 2010 World Health Organization HIV treatment guidelines in resource-limited settings: a model-based analysis. PLoS Med 2010;7:e1000382
-
(2010)
PLoS Med
, vol.7
-
-
Walensky, R.P.1
Wood, R.2
Ciaranello, A.L.3
-
101
-
-
53349171966
-
Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: Final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903
-
Berenguer J, Gonzalez J, Ribera E, et al. Didanosine, lamivudine, and efavirenz versus zidovudine, lamivudine, and efavirenz for the initial treatment of HIV type 1 infection: final analysis (48 weeks) of a prospective, randomized, noninferiority clinical trial, GESIDA 3903. Clin Infect Dis 2008;47:1083-92
-
(2008)
Clin Infect Dis
, vol.47
, pp. 1083-92
-
-
Berenguer, J.1
Gonzalez, J.2
Ribera, E.3
-
102
-
-
3142697068
-
Efficacy and safety of emtricitabine vs stavudine in combination therapy in antiretroviral-naive patients: A randomized trial
-
Saag MS, Cahn P, Raffi F, et al. Efficacy and safety of emtricitabine vs stavudine in combination therapy in antiretroviral-naive patients: a randomized trial. JAMA 2004;292:180-9
-
(2004)
JAMA
, vol.292
, pp. 180-9
-
-
Saag, M.S.1
Cahn, P.2
Raffi, F.3
-
103
-
-
77949434293
-
PEARLS (ACTG A5175): A multinational study of didanosine-EC emtricitabine and atazanavir vs. co-formulated zidovudine/lamivudine and efavirenz for initial treatment of HIV-1 infection
-
Mexico City Mexico
-
Campbell T, Smeaton L, Grutolla VD, et al. PEARLS (ACTG A5175): a multinational study of didanosine-EC, emtricitabine and atazanavir vs. co-formulated zidovudine/lamivudine and efavirenz for initial treatment of HIV-1 infection. In: 17th International AIDS Conference; Mexico City, Mexico; 2008
-
(2008)
17th International AIDS Conference
-
-
Campbell, T.1
Smeaton, L.2
Grutolla, V.D.3
-
104
-
-
77953586742
-
Rapid improvement in fasting lipids and hepatic toxicity after switching from didanosine/lamivudine to tenofovir/ emtricitabine in patients with toxicity attributable to didanosine
-
Palacios R, Rivero A, Santos I, et al. Rapid improvement in fasting lipids and hepatic toxicity after switching from didanosine/lamivudine to tenofovir/ emtricitabine in patients with toxicity attributable to didanosine. HIV Clin Trials 2010;11:118-20
-
(2010)
HIV Clin Trials
, vol.11
, pp. 118-20
-
-
Palacios, R.1
Rivero, A.2
Santos, I.3
-
106
-
-
67651086987
-
Association of noncirrhotic portal hypertension in HIV-infected persons and antiretroviral therapy with didanosine: A nested case-control study
-
Kovari H, Ledergerber B, Peter U, et al. Association of noncirrhotic portal hypertension in HIV-infected persons and antiretroviral therapy with didanosine: a nested case-control study. Clin Infect Dis 2009;49:626-35
-
(2009)
Clin Infect Dis
, vol.49
, pp. 626-35
-
-
Kovari, H.1
Ledergerber, B.2
Peter, U.3
-
107
-
-
22844433862
-
Mitochondrial toxicity of nucleoside analogues in primary human lymphocytes
-
Setzer B, Schlesier M, Thomas AK, Walker UA. Mitochondrial toxicity of nucleoside analogues in primary human lymphocytes. Antivir Ther 2005;10:327-34
-
(2005)
Antivir Ther
, vol.10
, pp. 327-34
-
-
Setzer, B.1
Schlesier, M.2
Thomas, A.K.3
Walker, U.A.4
-
108
-
-
23044486337
-
Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial
-
Maitland D, Moyle G, Hand J, et al. Early virologic failure in HIV-1 infected subjects on didanosine/ tenofovir/efavirenz: 12-week results from a randomized trial. AIDS 2005;19:1183-8
-
(2005)
AIDS
, vol.19
, pp. 1183-8
-
-
Maitland, D.1
Moyle, G.2
Hand, J.3
-
109
-
-
15744384550
-
Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine
-
Leon A, Martinez E, Mallolas J, et al. Early virological failure in treatment-naive HIV-infected adults receiving didanosine and tenofovir plus efavirenz or nevirapine. AIDS 2005;19:213-15
-
(2005)
AIDS
, vol.19
, pp. 213-15
-
-
Leon, A.1
Martinez, E.2
Mallolas, J.3
-
110
-
-
3042702514
-
Pancreatic toxic effects associated with co-administration of didanosine and tenofovir in HIV-infected adults
-
Martinez E, Milinkovic A, de Lazzari E, et al. Pancreatic toxic effects associated with co-administration of didanosine and tenofovir in HIV-infected adults. Lancet 2004;364:65-7
-
(2004)
Lancet
, vol.364
, pp. 65-7
-
-
Martinez, E.1
Milinkovic, A.2
De Lazzari, E.3
-
111
-
-
0346720608
-
ACTG 5095: A comparative study of 3 protease inhibitor-sparing antiretroviral regimens for the initial treatment of HIV infection
-
abstract 41
-
Gulick R, Ribaudo H, Shikuma C, et al. ACTG 5095: a comparative study OF 3 protease inhibitor-sparing antiretroviral regimens for the initial treatment of HIV infection. Antivir Ther 2003;8(Suppl 1):abstract 41
-
(2003)
Antivir Ther
, vol.8
, Issue.SUPPL. 1
-
-
Gulick, R.1
Ribaudo, H.2
Shikuma, C.3
-
112
-
-
77953160346
-
Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts
-
Munderi P, Walker AS, Kityo C, et al. Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/ lamivudine in HIV-infected Ugandan adults with low CD4 cell counts. HIV Med 2010;11:334-44
-
(2010)
HIV Med
, vol.11
, pp. 334-44
-
-
Munderi, P.1
Walker, A.S.2
Kityo, C.3
-
113
-
-
27944472569
-
Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects
-
Gallant JE, Rodriguez AE, Weinberg WG, et al. Early virologic nonresponse to tenofovir, abacavir, and lamivudine in HIV-infected antiretroviral-naive subjects. J Infect Dis 2005;192:1921-30
-
(2005)
J Infect Dis
, vol.192
, pp. 1921-30
-
-
Gallant, J.E.1
Rodriguez, A.E.2
Weinberg, W.G.3
-
114
-
-
33644766239
-
Early virologic failure and rescue therapy of tenofovir, abacavir, and lamivudine for initial treatment of HIV-1 infection: TONUS study
-
Landman R, Descamps D, Peytavin G, et al. Early virologic failure and rescue therapy of tenofovir, abacavir, and lamivudine for initial treatment of HIV-1 infection: TONUS study. HIV Clin Trials 2005;6:291-301
-
(2005)
HIV Clin Trials
, vol.6
, pp. 291-301
-
-
Landman, R.1
Descamps, D.2
Peytavin, G.3
-
115
-
-
48749124843
-
Zidovudine/ Lamivudine/Abacavir plus tenofovir in HIV-infected naive patients: A 96-week prospective One-Arm Pilot Study
-
Ferrer E, Gatell JM, Sanchez P, et al. Zidovudine/ Lamivudine/Abacavir plus tenofovir in HIV-infected naive patients: a 96-week prospective One-Arm Pilot Study. AIDS Res Hum Retroviruses 2008;24:931-4
-
(2008)
AIDS Res Hum Retroviruses
, vol.24
, pp. 931-4
-
-
Ferrer, E.1
Gatell, J.M.2
Sanchez, P.3
-
116
-
-
85056043870
-
Efficacy and safety of Abacavir/Lamivudine/Zidovudine plus tenofovir in HBV/HIV-1 coinfected adults: 48-week Data
-
Rodriguez AE, Dejesus E, Williams V, et al. Efficacy and safety of Abacavir/Lamivudine/Zidovudine plus tenofovir in HBV/HIV-1 coinfected adults: 48-week Data. Open AIDS J 2010;4:167-70
-
(2010)
Open AIDS J
, vol.4
, pp. 167-70
-
-
Rodriguez, A.E.1
Dejesus, E.2
Williams, V.3
-
117
-
-
77957842048
-
Efavirenz versus boosted atazanavir or zidovudine and abacavir in antiretroviral treatment-naive, HIV-infected subjects: Week 48 data from the Altair study
-
Puls RL, Srasuebkul P, Petoumenos K, et al. Efavirenz versus boosted atazanavir or zidovudine and abacavir in antiretroviral treatment-naive, HIV-infected subjects: week 48 data from the Altair study. Clin Infect Dis 2010;51:855-64
-
(2010)
Clin Infect Dis
, vol.51
, pp. 855-64
-
-
Puls, R.L.1
Srasuebkul, P.2
Petoumenos, K.3
-
118
-
-
79953799570
-
HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries
-
van de Vijver DA, Wensing AM, Asjo B, et al. HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries. Acta Dermatovenerol Alp Panonica Adriat 2010;19:3-9
-
(2010)
Acta Dermatovenerol Alp Panonica Adriat
, vol.19
, pp. 3-9
-
-
Van De Vijver, D.A.1
Wensing, A.M.2
Asjo, B.3
-
119
-
-
79953733544
-
Update on human immunodeficiency virus (HIV)-2 infection
-
Campbell-Yesufu OT, Gandhi RT. Update on human immunodeficiency virus (HIV)-2 infection. Clin Infect Dis 2011;52:780-7
-
(2011)
Clin Infect Dis
, vol.52
, pp. 780-7
-
-
Campbell-Yesufu, O.T.1
Gandhi, R.T.2
-
120
-
-
70349091852
-
Antiretroviral drug resistance in human immunodeficiency virus type 2
-
Ntemgwa ML, Toni TdA, Brenner BG, et al. Antiretroviral drug resistance in human immunodeficiency virus type 2. Antimicrob Agents Chemother 2009;53:3611-19
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3611-19
-
-
Ntemgwa, M.L.1
Tda, T.2
Brenner, B.G.3
-
121
-
-
42049104340
-
In vitro phenotypic susceptibility of human immunodeficiency virus type 2 clinical isolates to protease inhibitors
-
Desbois D, Roquebert B, Peytavin G, et al. In vitro phenotypic susceptibility of human immunodeficiency virus type 2 clinical isolates to protease inhibitors. Antimicrob Agents Chemother 2008;52:1545-8
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1545-8
-
-
Desbois, D.1
Roquebert, B.2
Peytavin, G.3
-
122
-
-
78650219266
-
First real success for anti-HIV gel: A new start for HIV microbicides?
-
Arien KK, Vanham G. First real success for anti-HIV gel: a new start for HIV microbicides? Future Microbiol 2010;5:1621-3
-
(2010)
Future Microbiol
, vol.5
, pp. 1621-3
-
-
Arien, K.K.1
Vanham, G.2
-
123
-
-
77955930318
-
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
-
Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010;329:1168-74
-
(2010)
Science
, vol.329
, pp. 1168-74
-
-
Abdool Karim, Q.1
Abdool Karim, S.S.2
Frohlich, J.A.3
-
124
-
-
78650549662
-
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men
-
Grant RM, Lama JR, Anderson PL, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010;363:2587-99
-
(2010)
N Engl J Med
, vol.363
, pp. 2587-99
-
-
Grant, R.M.1
Lama, J.R.2
Anderson, P.L.3
-
125
-
-
81855182397
-
Antiretroviral pre-exposure prophylaxis for HIV-1 prevention among heterosexual African men and women: The Partners PrEP Study [MOAX0106]
-
Rome Italy
-
Baeten J, Celum C. Antiretroviral pre-exposure prophylaxis for HIV-1 prevention among heterosexual African men and women: the Partners PrEP Study [MOAX0106]. In: 6th IAS Conference on HIV Pathogenesis, Treatment and Prevention; Rome, Italy; 2011
-
(2011)
6th IAS Conference on HIV Pathogenesis Treatment and Prevention
-
-
Baeten, J.1
Celum, C.2
-
126
-
-
43549094732
-
Class-Sparing Regimens for Initial Treatment of HIV-1 Infection
-
Riddler SA, Haubrich R, DiRienzo AG, et al. Class-Sparing Regimens for Initial Treatment of HIV-1 Infection. N Engl J Med 2008;358:2095-106
-
(2008)
N Engl J Med
, vol.358
, pp. 2095-106
-
-
Riddler, S.A.1
Haubrich, R.2
Dirienzo, A.G.3
-
127
-
-
79952668356
-
Lopinavir/ritonavir combined with raltegravir demonstrated similar antiviral efficacy and safety as lopinavir/ritonavir combined with tenofovir disoproxil fumarate/emtricitabine in treatment-naive HIV-1 infected subjects [MOAB0101]
-
Vienna Austria
-
Reynes J, Lawal A, Pulido A, et al. Lopinavir/ritonavir combined with raltegravir demonstrated similar antiviral efficacy and safety as lopinavir/ritonavir combined with tenofovir disoproxil fumarate/emtricitabine in treatment-naive HIV-1 infected subjects [MOAB0101]. In: XVIII International AIDS Conference; Vienna, Austria; 2010
-
(2010)
XVIII International AIDS Conference
-
-
Reynes, J.1
Lawal, A.2
Pulido, A.3
-
128
-
-
80055028058
-
Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262)
-
Taiwo B, Zheng L, Gallien S, et al. Efficacy of a nucleoside-sparing regimen of darunavir/ritonavir plus raltegravir in treatment-naive HIV-1-infected patients (ACTG A5262). AIDS 2011;25:2113-22
-
(2011)
AIDS
, vol.25
, pp. 2113-22
-
-
Taiwo, B.1
Zheng, L.2
Gallien, S.3
-
129
-
-
74249086332
-
The MONET trial: Darunavir/ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml
-
Arribas JR, Horban A, Gerstoft J, et al. The MONET trial: darunavir/ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml. AIDS 2010;24:223-30
-
(2010)
AIDS
, vol.24
, pp. 223-30
-
-
Arribas, J.R.1
Horban, A.2
Gerstoft, J.3
-
130
-
-
77957230936
-
Efficacy of darunavir/ritonavir maintenance monotherapy in patients with HIV-1 viral suppression: A randomized open-label, noninferiority trial, MONOI-ANRS 136
-
Katlama C, Valantin MA, Algarte-Genin M, et al. Efficacy of darunavir/ritonavir maintenance monotherapy in patients with HIV-1 viral suppression: a randomized open-label, noninferiority trial, MONOI-ANRS 136. AIDS 2010;24:2365-74
-
(2010)
AIDS
, vol.24
, pp. 2365-74
-
-
Katlama, C.1
Valantin, M.A.2
Algarte-Genin, M.3
-
131
-
-
83455264209
-
GS-7340 Demonstrates greater declines in HIV-1 RNA than tenofovir disoproxilfumarate during 14 days of monotherapyin HIV-1 infected subjects
-
Boston
-
Markowitz M, Zolopa A, Ruane P, et al. GS-7340 Demonstrates greater declines in HIV-1 RNA than tenofovir disoproxilfumarate during 14 days of monotherapyin HIV-1 infected subjects. In: 18th Conference on Retroviruses and Opportunistic Infections (CROI 2011); Boston; 2011
-
(2011)
18th Conference on Retroviruses and Opportunistic Infections (CROI 2011)
-
-
Markowitz, M.1
Zolopa, A.2
Ruane, P.3
-
132
-
-
77950255107
-
Resistance profile of the new nucleoside reverse transcriptase inhibitor apricitabine
-
Cahn P, Wainberg MA. Resistance profile of the new nucleoside reverse transcriptase inhibitor apricitabine. J Antimicrob Chemother 2010;65:213-17
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 213-17
-
-
Cahn, P.1
Wainberg, M.A.2
-
133
-
-
77950666839
-
Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals
-
Murphy RL, Kivel NM, Zala C, et al. Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals. Antivir Ther 2010;15:185-92
-
(2010)
Antivir Ther
, vol.15
, pp. 185-92
-
-
Murphy, R.L.1
Kivel, N.M.2
Zala, C.3
|