Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring

Journal of Infectious Diseases

Volumn 178, Issue 5, 1998, Pages 1327-1333

  Moodley, J ^a,b,c,d,e   Moodley, Dhayendre ^a,b,c,d,e   Pillay, K ^a,b,c,d,e   Coovadia, H ^a,b,c,d,e   Saba, J ^a,b,c,d,e   van Leeuwen, R ^a,b,c,d,e   Goodwin, C ^a,b,c,d,e   Harrigan, P R ^a,b,c,d,e   Moore, K H P ^a,b,c,d,e   Stone, C ^a,b,c,d,e   Plumb, R ^a,b,c,d,e   Johnson, M A ^a,b,c,d,e  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b UNAIDS   (Switzerland)

^c Natl AIDS Therapy Evaluation Centre   (Netherlands)

^d GLAXOSMITHKLINE   (United Kingdom)

^e BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; LAMIVUDINE; ZIDOVUDINE;

ADULT; ANTIVIRAL ACTIVITY; ARTICLE; CLINICAL ARTICLE; DELIVERY; DRUG SAFETY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; VIRUS TRANSMISSION;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AFRICAN CONTINENTAL ANCESTRY GROUP; AMNIOTIC FLUID; ANTI-HIV AGENTS; DISEASE TRANSMISSION, VERTICAL; DRUG THERAPY, COMBINATION; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; INFANT, NEWBORN; LAMIVUDINE; MILK, HUMAN; PREGNANCY; RANDOM ALLOCATION; RNA, VIRAL; SOUTH AFRICA; VIRAL LOAD; ZIDOVUDINE;

EID: 0031723646     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/314431     Document Type: Article

References (5)

1. Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med 1994;331:73-80.
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4. Njenga SN, Embree JE, Ndinya-Achola JO, et al. Risk factors for postnatal mother-to-child transmission HIV-1 in Nairobi. In: Programs and Abstracts of the Conference on Global Strategies for the Prevention of HIV Transmission from Mothers-to-Infants, Washington, DC, 1997:10.
5. John GC, Kreiss J. Mother-to-child transmission of HIV-1. Epidemiol Rev 1996:18:149-57.