Progression of spontaneous autoimmune diabetes is associated with a switch in the killing mechanism used by autoreactive CTL

International Immunology

Volumn 16, Issue 11, 2004, Pages 1657-1662

  Qin, Huilian ^a   Trudeau, Jacqueline D ^a   Reid, Gregor S D ^b   Lee, I Fang ^a   Dutz, Jan P ^b   Santamaria, Pere ^c   Verchere, C Bruce ^a   Tan, Rusung ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Avidity maturation; CTL; Fas; Non obese diabetic; Perforin

Indexed keywords

CD8 ANTIGEN; FAS LIGAND; PERFORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; CELL KILLING; CELL SPECIFICITY; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DIABETES MELLITUS; DIABETOGENESIS; DISEASE ASSOCIATION; DISEASE COURSE; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET CELL; TRANSGENIC MOUSE;

AGING; ANIMALS; CYTOTOXICITY, IMMUNOLOGIC; DIABETES MELLITUS, TYPE 1; GENES, T-CELL RECEPTOR BETA; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, TRANSGENIC; T-LYMPHOCYTES, CYTOTOXIC;

EID: 8344278886     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh167     Document Type: Article

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