Paxillin mediates sensing of physical cues and regulates directional cell motility by controlling lamellipodia positioning

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Sero, Julia E ^a,e   Thodeti, Charles K ^a,f   Mammoto, Akiko ^a   Bakal, Chris ^e   Thomas, Sheila ^b   Ingber, Donald E ^a,c,d  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD UNIVERSITY   (United States)

^d HARVARD UNIVERSITY   (United States)

^e INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^f Northeastern Ohio Medical University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PAXILLIN; PLATELET DERIVED GROWTH FACTOR BB; RAC PROTEIN; COLLAGEN; LAMININ; MATRIGEL; PLATELET DERIVED GROWTH FACTOR; PROTEOGLYCAN; VINCULIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; CELL MIGRATION; CELL MOTILITY; CELL SHAPE; CELL SIZE; CELL SURFACE; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; FIBROBLAST CULTURE; FOCAL ADHESION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LAMELLIPODIUM; NEWBORN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; ANIMAL; ANIMAL EMBRYO; CELL ADHESION; CELL COUNT; CELL MEMBRANE; CELL MOTION; CHEMISTRY; CHICKEN; CYTOLOGY; DRUG COMBINATION; DRUG EFFECT; FIBROBLAST; GENE INACTIVATION; GENETICS; METABOLISM; MOUSE; MUTATION; PHENOTYPE; PSEUDOPODIUM; TIME;

ANIMALS; CELL ADHESION; CELL COUNT; CELL MEMBRANE; CELL MOVEMENT; CHICKENS; COLLAGEN; DRUG COMBINATIONS; EMBRYO, MAMMALIAN; EXTRACELLULAR MATRIX; FIBROBLASTS; FOCAL ADHESIONS; GENE KNOCKOUT TECHNIQUES; HUMANS; LAMININ; MICE; MUTATION; PAXILLIN; PHENOTYPE; PLATELET-DERIVED GROWTH FACTOR; PROTEOGLYCANS; PSEUDOPODIA; RAC GTP-BINDING PROTEINS; TIME FACTORS; VINCULIN;

EID: 83355173170     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028303     Document Type: Article

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