메뉴 건너뛰기




Volumn 78, Issue 1, 2012, Pages 138-141

The existence of two types of proteasome, the constitutive proteasome and the immunoproteasome, may serve as another layer of protection against autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

CONSTITUTIVE PROTEASOME; IMMUNOPROTEASOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; UNCLASSIFIED DRUG;

EID: 83155175088     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2011.10.010     Document Type: Article
Times cited : (7)

References (54)
  • 1
    • 0037066502 scopus 로고    scopus 로고
    • Decoding the patterns of self and nonself by the innate immune system
    • Medzhitov R., Janeway C.A. Decoding the patterns of self and nonself by the innate immune system. Science 2002, 296:298-300.
    • (2002) Science , vol.296 , pp. 298-300
    • Medzhitov, R.1    Janeway, C.A.2
  • 2
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: a renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002, 296:301-305.
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 3
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A., Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004, 5:987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 4
    • 2942541735 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens
    • Heath W.R., Belz G.T., Behrens G.M., Smith C.M., Forehan S.P., Parish I.A., et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol Rev 2004, 199:9-26.
    • (2004) Immunol Rev , vol.199 , pp. 9-26
    • Heath, W.R.1    Belz, G.T.2    Behrens, G.M.3    Smith, C.M.4    Forehan, S.P.5    Parish, I.A.6
  • 6
    • 34247146913 scopus 로고    scopus 로고
    • The final touches make perfect the peptide-MHC class I repertoire
    • Hammer G.E., Kanaseki T., Shastri N. The final touches make perfect the peptide-MHC class I repertoire. Immunity 2007, 26:397-406.
    • (2007) Immunity , vol.26 , pp. 397-406
    • Hammer, G.E.1    Kanaseki, T.2    Shastri, N.3
  • 7
    • 72949103056 scopus 로고    scopus 로고
    • Proteasomes in immune cells: more than peptide producers?
    • Groettrup M., Kirk C.J., Basler M. Proteasomes in immune cells: more than peptide producers? Nat Rev Immunol 2010, 10:73-78.
    • (2010) Nat Rev Immunol , vol.10 , pp. 73-78
    • Groettrup, M.1    Kirk, C.J.2    Basler, M.3
  • 8
    • 65649115267 scopus 로고    scopus 로고
    • Recognition and processing of ubiquitin-protein conjugates by the proteasome
    • Finley D. Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu Rev Biochem 2009, 78:477-513.
    • (2009) Annu Rev Biochem , vol.78 , pp. 477-513
    • Finley, D.1
  • 10
    • 0032730872 scopus 로고    scopus 로고
    • Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation
    • Macagno A., Gilliet M., Sallusto F., Lanzavecchia A., Nestle F.O., Groettrup M. Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation. Eur J Immunol 1999, 29:4037-4042.
    • (1999) Eur J Immunol , vol.29 , pp. 4037-4042
    • Macagno, A.1    Gilliet, M.2    Sallusto, F.3    Lanzavecchia, A.4    Nestle, F.O.5    Groettrup, M.6
  • 11
    • 0035214302 scopus 로고    scopus 로고
    • Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation
    • Li J., Schuler-Thurner B., Schuler G., Huber C., Seliger B. Bipartite regulation of different components of the MHC class I antigen-processing machinery during dendritic cell maturation. Int Immunol 2001, 13:1515-1523.
    • (2001) Int Immunol , vol.13 , pp. 1515-1523
    • Li, J.1    Schuler-Thurner, B.2    Schuler, G.3    Huber, C.4    Seliger, B.5
  • 12
    • 0027214605 scopus 로고
    • Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes
    • Gaczynska M., Rock K.L., Goldberg A.L. Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes. Nature 1993, 365:264-267.
    • (1993) Nature , vol.365 , pp. 264-267
    • Gaczynska, M.1    Rock, K.L.2    Goldberg, A.L.3
  • 13
    • 0027223877 scopus 로고
    • MHC-linked LMP gene products specifically alter peptidase activities of the proteasome
    • Driscoll J., Brown M.G., Finley D., Monaco J.J. MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature 1993, 365:262-264.
    • (1993) Nature , vol.365 , pp. 262-264
    • Driscoll, J.1    Brown, M.G.2    Finley, D.3    Monaco, J.J.4
  • 14
    • 0029162601 scopus 로고
    • Incorporation of major histocompatibility complex-encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon-gamma
    • Kuckelkorn U., Frentzel S., Kraft R., Kostka S., Groettrup M., Kloetzel P.M. Incorporation of major histocompatibility complex-encoded subunits LMP2 and LMP7 changes the quality of the 20S proteasome polypeptide processing products independent of interferon-gamma. Eur J Immunol 1995, 25:2605-2611.
    • (1995) Eur J Immunol , vol.25 , pp. 2605-2611
    • Kuckelkorn, U.1    Frentzel, S.2    Kraft, R.3    Kostka, S.4    Groettrup, M.5    Kloetzel, P.M.6
  • 15
    • 0035290730 scopus 로고    scopus 로고
    • Antigen processing by the proteasome
    • Kloetzel P.M. Antigen processing by the proteasome. Nat Rev Mol Cell Biol 2001, 2:179-187.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 179-187
    • Kloetzel, P.M.1
  • 16
    • 72949104779 scopus 로고    scopus 로고
    • Antigen presentation in the thymus for positive selection and central tolerance induction
    • Klein L., Hinterberger M., Wirnsberger G., Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol 2009, 9:833-844.
    • (2009) Nat Rev Immunol , vol.9 , pp. 833-844
    • Klein, L.1    Hinterberger, M.2    Wirnsberger, G.3    Kyewski, B.4
  • 17
    • 0035806246 scopus 로고    scopus 로고
    • Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens
    • Chen W., Norbury C.C., Cho Y., Yewdell J.W., Bennink J.R. Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens. J Exp Med 2001, 193:1319-1326.
    • (2001) J Exp Med , vol.193 , pp. 1319-1326
    • Chen, W.1    Norbury, C.C.2    Cho, Y.3    Yewdell, J.W.4    Bennink, J.R.5
  • 18
    • 7244239199 scopus 로고    scopus 로고
    • Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets
    • Nil A., Firat E., Sobek V., Eichmann K., Niedermann G. Expression of housekeeping and immunoproteasome subunit genes is differentially regulated in positively and negatively selecting thymic stroma subsets. Eur J Immunol 2004, 34:2681-2689.
    • (2004) Eur J Immunol , vol.34 , pp. 2681-2689
    • Nil, A.1    Firat, E.2    Sobek, V.3    Eichmann, K.4    Niedermann, G.5
  • 21
    • 0034610973 scopus 로고    scopus 로고
    • High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice. mechanisms of selection of the self-reactive repertoire
    • Anderson A.C., Nicholson L.B., Legge K.L., Turchin V., Zaghouani H., Kuchroo V.K. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice. mechanisms of selection of the self-reactive repertoire. J Exp Med 2000, 191:761-770.
    • (2000) J Exp Med , vol.191 , pp. 761-770
    • Anderson, A.C.1    Nicholson, L.B.2    Legge, K.L.3    Turchin, V.4    Zaghouani, H.5    Kuchroo, V.K.6
  • 22
    • 0034507693 scopus 로고    scopus 로고
    • Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion
    • Bouneaud C., Kourilsky P., Bousso P. Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion. Immunity 2000, 13:829-840.
    • (2000) Immunity , vol.13 , pp. 829-840
    • Bouneaud, C.1    Kourilsky, P.2    Bousso, P.3
  • 23
    • 0036533552 scopus 로고    scopus 로고
    • Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance
    • Yan J., Mamula M.J. Autoreactive T cells revealed in the normal repertoire: escape from negative selection and peripheral tolerance. J Immunol 2002, 168:3188-3194.
    • (2002) J Immunol , vol.168 , pp. 3188-3194
    • Yan, J.1    Mamula, M.J.2
  • 24
    • 33748621205 scopus 로고    scopus 로고
    • Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells
    • Eleftheriadis T., Voyatzi S., Antoniadi G., Kartsios C., Liakopoulos V., Paraskevopoulos P., et al. Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells. Cell Immunol 2006, 240:62-67.
    • (2006) Cell Immunol , vol.240 , pp. 62-67
    • Eleftheriadis, T.1    Voyatzi, S.2    Antoniadi, G.3    Kartsios, C.4    Liakopoulos, V.5    Paraskevopoulos, P.6
  • 25
    • 44749085669 scopus 로고    scopus 로고
    • Thymoproteasome: probable role in generating positively selecting peptides
    • Murata S., Takahama Y., Tanaka K. Thymoproteasome: probable role in generating positively selecting peptides. Curr Opin Immunol 2008, 20:192-196.
    • (2008) Curr Opin Immunol , vol.20 , pp. 192-196
    • Murata, S.1    Takahama, Y.2    Tanaka, K.3
  • 26
    • 0028037781 scopus 로고
    • CDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y
    • Akiyama K., Yokota K., Kagawa S., Shimbara N., Tamura T., Akioka H., et al. CDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y. Science 1994, 265:1231-1234.
    • (1994) Science , vol.265 , pp. 1231-1234
    • Akiyama, K.1    Yokota, K.2    Kagawa, S.3    Shimbara, N.4    Tamura, T.5    Akioka, H.6
  • 27
    • 0028097823 scopus 로고
    • Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes
    • Boes B., Hengel H., Ruppert T., Multhaup G., Koszinowski U.H., Kloetzel P.M. Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes. J Exp Med 1994, 179:901-909.
    • (1994) J Exp Med , vol.179 , pp. 901-909
    • Boes, B.1    Hengel, H.2    Ruppert, T.3    Multhaup, G.4    Koszinowski, U.H.5    Kloetzel, P.M.6
  • 28
    • 0035883047 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface
    • Hallermalm K., Seki K., Wei C., Castelli C., Rivoltini L., Kiessling R., et al. Tumor necrosis factor-alpha induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface. Blood 2001, 98:1108-1115.
    • (2001) Blood , vol.98 , pp. 1108-1115
    • Hallermalm, K.1    Seki, K.2    Wei, C.3    Castelli, C.4    Rivoltini, L.5    Kiessling, R.6
  • 29
    • 0036401590 scopus 로고    scopus 로고
    • Immunoproteasome expression in a nonimmune tissue, the ocular lens
    • Singh S., Awasthi N., Egwuagu C.E., Wagner B.J. Immunoproteasome expression in a nonimmune tissue, the ocular lens. Arch Biochem Biophys 2002, 405:147-153.
    • (2002) Arch Biochem Biophys , vol.405 , pp. 147-153
    • Singh, S.1    Awasthi, N.2    Egwuagu, C.E.3    Wagner, B.J.4
  • 30
    • 33746581248 scopus 로고    scopus 로고
    • Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma
    • Leblond J., Hubert-Buron A., Bole-Feysot C., Ducrotte P., Dechelotte P., Coeffier M. Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma. Biochimie 2006, 88:759-765.
    • (2006) Biochimie , vol.88 , pp. 759-765
    • Leblond, J.1    Hubert-Buron, A.2    Bole-Feysot, C.3    Ducrotte, P.4    Dechelotte, P.5    Coeffier, M.6
  • 32
    • 33750597617 scopus 로고    scopus 로고
    • Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
    • Shin E.C., Seifert U., Kato T., Rice C.M., Feinstone S.M., Kloetzel P.M., et al. Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection. J Clin Invest 2006, 116:3006-3014.
    • (2006) J Clin Invest , vol.116 , pp. 3006-3014
    • Shin, E.C.1    Seifert, U.2    Kato, T.3    Rice, C.M.4    Feinstone, S.M.5    Kloetzel, P.M.6
  • 33
    • 0035892754 scopus 로고    scopus 로고
    • Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
    • Khan S., van den Broek M., Schwarz K., de Giuli R., Diener P.A., Groettrup M. Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J Immunol 2001, 167:6859-6868.
    • (2001) J Immunol , vol.167 , pp. 6859-6868
    • Khan, S.1    van den Broek, M.2    Schwarz, K.3    de Giuli, R.4    Diener, P.A.5    Groettrup, M.6
  • 34
    • 0037105392 scopus 로고    scopus 로고
    • Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection
    • Barton L.F., Cruz M., Rangwala R., Deepe G.S., Monaco J.J. Regulation of immunoproteasome subunit expression in vivo following pathogenic fungal infection. J Immunol 2002, 169:3046-3052.
    • (2002) J Immunol , vol.169 , pp. 3046-3052
    • Barton, L.F.1    Cruz, M.2    Rangwala, R.3    Deepe, G.S.4    Monaco, J.J.5
  • 35
    • 0033485429 scopus 로고    scopus 로고
    • Generation of an immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic protein
    • Gileadi U., Moins-Teisserenc H.T., Correa I., Booth B.L., Dunbar P.R., Sewell A.K., et al. Generation of an immunodominant CTL epitope is affected by proteasome subunit composition and stability of the antigenic protein. J Immunol 1999, 163:6045-6052.
    • (1999) J Immunol , vol.163 , pp. 6045-6052
    • Gileadi, U.1    Moins-Teisserenc, H.T.2    Correa, I.3    Booth, B.L.4    Dunbar, P.R.5    Sewell, A.K.6
  • 36
    • 0034698738 scopus 로고    scopus 로고
    • Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28
    • van Hall T., Sijts A., Camps M., Offringa R., Melief C., Kloetzel P.M., et al. Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28. J Exp Med 2000, 192:483-494.
    • (2000) J Exp Med , vol.192 , pp. 483-494
    • van Hall, T.1    Sijts, A.2    Camps, M.3    Offringa, R.4    Melief, C.5    Kloetzel, P.M.6
  • 37
    • 0033980648 scopus 로고    scopus 로고
    • Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells
    • Morel S., Levy F., Burlet-Schiltz O., Brasseur F., Probst-Kepper M., Peitrequin A.L., et al. Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells. Immunity 2000, 12:107-117.
    • (2000) Immunity , vol.12 , pp. 107-117
    • Morel, S.1    Levy, F.2    Burlet-Schiltz, O.3    Brasseur, F.4    Probst-Kepper, M.5    Peitrequin, A.L.6
  • 38
    • 0035796461 scopus 로고    scopus 로고
    • Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
    • Toes R.E., Nussbaum A.K., Degermann S., Schirle M., Emmerich N.P., Kraft M., et al. Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J Exp Med 2001, 194:1-12.
    • (2001) J Exp Med , vol.194 , pp. 1-12
    • Toes, R.E.1    Nussbaum, A.K.2    Degermann, S.3    Schirle, M.4    Emmerich, N.P.5    Kraft, M.6
  • 39
    • 0035314002 scopus 로고    scopus 로고
    • Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome
    • Van den Eynde B.J., Morel S. Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome. Curr Opin Immunol 2001, 13:147-153.
    • (2001) Curr Opin Immunol , vol.13 , pp. 147-153
    • Van den Eynde, B.J.1    Morel, S.2
  • 40
    • 0242468319 scopus 로고    scopus 로고
    • Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome
    • Kesmir C., van Noort V., de Boer R.J., Hogeweg P. Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome. Immunogenetics 2003, 55:437-449.
    • (2003) Immunogenetics , vol.55 , pp. 437-449
    • Kesmir, C.1    van Noort, V.2    de Boer, R.J.3    Hogeweg, P.4
  • 41
    • 30744465074 scopus 로고    scopus 로고
    • Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation
    • Chapiro J., Claverol S., Piette F., Ma W., Stroobant V., Guillaume B., et al. Destructive cleavage of antigenic peptides either by the immunoproteasome or by the standard proteasome results in differential antigen presentation. J Immunol 2006, 176:1053-1061.
    • (2006) J Immunol , vol.176 , pp. 1053-1061
    • Chapiro, J.1    Claverol, S.2    Piette, F.3    Ma, W.4    Stroobant, V.5    Guillaume, B.6
  • 42
    • 33846083832 scopus 로고    scopus 로고
    • Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus
    • Robek M.D., Garcia M.L., Boyd B.S., Chisari F.V. Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. J Virol 2007, 81:483-491.
    • (2007) J Virol , vol.81 , pp. 483-491
    • Robek, M.D.1    Garcia, M.L.2    Boyd, B.S.3    Chisari, F.V.4
  • 43
    • 39649085607 scopus 로고    scopus 로고
    • Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity
    • Dannull J., Lesher D.T., Holzknecht R., Qi W., Hanna G., Seigler H., et al. Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity. Blood 2007, 110:4341-4350.
    • (2007) Blood , vol.110 , pp. 4341-4350
    • Dannull, J.1    Lesher, D.T.2    Holzknecht, R.3    Qi, W.4    Hanna, G.5    Seigler, H.6
  • 44
    • 78650359178 scopus 로고    scopus 로고
    • Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome
    • Dalet A., Stroobant V., Vigneron N., Van den Eynde B.J. Differences in the production of spliced antigenic peptides by the standard proteasome and the immunoproteasome. Eur J Immunol 2011, 41:39-46.
    • (2011) Eur J Immunol , vol.41 , pp. 39-46
    • Dalet, A.1    Stroobant, V.2    Vigneron, N.3    Van den Eynde, B.J.4
  • 46
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • Swann J.B., Smyth M.J. Immune surveillance of tumors. J Clin Invest 2007, 117:1137-1146.
    • (2007) J Clin Invest , vol.117 , pp. 1137-1146
    • Swann, J.B.1    Smyth, M.J.2
  • 47
    • 79951822288 scopus 로고    scopus 로고
    • A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy
    • Ma W., Vigneron N., Chapiro J., Stroobant V., Germeau C., Boon T., et al. A MAGE-C2 antigenic peptide processed by the immunoproteasome is recognized by cytolytic T cells isolated from a melanoma patient after successful immunotherapy. Int J Cancer 2011.
    • (2011) Int J Cancer
    • Ma, W.1    Vigneron, N.2    Chapiro, J.3    Stroobant, V.4    Germeau, C.5    Boon, T.6
  • 48
    • 33646474855 scopus 로고    scopus 로고
    • Tissue-specific up-regulation of the proteasome subunit beta5i (LMP7) in Sjogren's syndrome
    • Egerer T., Martinez-Gamboa L., Dankof A., Stuhlmuller B., Dorner T., Krenn V., et al. Tissue-specific up-regulation of the proteasome subunit beta5i (LMP7) in Sjogren's syndrome. Arthritis Rheum 2006, 54:1501-1508.
    • (2006) Arthritis Rheum , vol.54 , pp. 1501-1508
    • Egerer, T.1    Martinez-Gamboa, L.2    Dankof, A.3    Stuhlmuller, B.4    Dorner, T.5    Krenn, V.6
  • 51
    • 67650388103 scopus 로고    scopus 로고
    • A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
    • Muchamuel T., Basler M., Aujay M.A., Suzuki E., Kalim K.W., Lauer C., et al. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat Med 2009, 15:781-787.
    • (2009) Nat Med , vol.15 , pp. 781-787
    • Muchamuel, T.1    Basler, M.2    Aujay, M.A.3    Suzuki, E.4    Kalim, K.W.5    Lauer, C.6
  • 52
    • 77956198116 scopus 로고    scopus 로고
    • Prevention of experimental colitis by a selective inhibitor of the immunoproteasome
    • Basler M., Dajee M., Moll C., Groettrup M., Kirk C.J. Prevention of experimental colitis by a selective inhibitor of the immunoproteasome. J Immunol 2010, 185:634-641.
    • (2010) J Immunol , vol.185 , pp. 634-641
    • Basler, M.1    Dajee, M.2    Moll, C.3    Groettrup, M.4    Kirk, C.J.5
  • 53
    • 31544479100 scopus 로고    scopus 로고
    • Molecular mimicry, bystander activation, or viral persistence. infections and autoimmune disease
    • Fujinami R.S., von Herrath M.G., Christen U., Whitton J.L. Molecular mimicry, bystander activation, or viral persistence. infections and autoimmune disease. Clin Microbiol Rev 2006, 19:80-94.
    • (2006) Clin Microbiol Rev , vol.19 , pp. 80-94
    • Fujinami, R.S.1    von Herrath, M.G.2    Christen, U.3    Whitton, J.L.4
  • 54
    • 77951221088 scopus 로고    scopus 로고
    • Autoimmunity, infection and adjuvants
    • Rose N.R. Autoimmunity, infection and adjuvants. Lupus 2010, 19:354-358.
    • (2010) Lupus , vol.19 , pp. 354-358
    • Rose, N.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.