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Volumn 21, Issue 1, 2012, Pages 97-105

PPARγ as a therapeutic target in diabetic nephropathy and other renal diseases

Author keywords

diabetic nephropathy; hypertension; kidney injury; PPAR

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALPHA TOCOPHEROL; CISPLATIN; DAUNORUBICIN; DOCOSAHEXAENOIC ACID; GAMMA TOCOPHEROL; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; ICOSAPENTAENOIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 2; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; STREPTOZOCIN; TELMISARTAN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 83055196577     PISSN: 10624821     EISSN: 14736543     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32834de526     Document Type: Review
Times cited : (67)

References (128)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010; 87:4-14.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 77950263954 scopus 로고    scopus 로고
    • Prevalence of diabetes among men and women in China
    • Yang W, Lu J, Weng J, et al. Prevalence of diabetes among men and women in China. N Engl J Med 2010; 362:1090-1101.
    • (2010) N Engl J Med , vol.362 , pp. 1090-1101
    • Yang, W.1    Lu, J.2    Weng, J.3
  • 3
    • 36248983781 scopus 로고    scopus 로고
    • Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy?
    • DOI 10.1038/sj.ki.5002557, PII 5002557
    • Zheng F, Guan Y. Thiazolidinediones: a novel class of drugs for the prevention of diabetic nephropathy? Kidney Int 2007; 72:1301-1303. (Pubitemid 350126785)
    • (2007) Kidney International , vol.72 , Issue.11 , pp. 1301-1303
    • Zheng, F.1    Guan, Y.2
  • 5
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARgamma
    • Lehrke M, Lazar MA. The many faces of PPARgamma. Cell 2005; 123:993-999.
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 6
    • 34347333419 scopus 로고    scopus 로고
    • PPAR ligands: Are they potential agents for cardiovascular disorders?
    • DOI 10.1159/000102594
    • Balakumar P, Rose M, Singh M. PPAR ligands: are they potential agents for cardiovascular disorders? Pharmacology 2007; 80:1-10. (Pubitemid 47013361)
    • (2007) Pharmacology , vol.80 , Issue.1 , pp. 1-10
    • Balakumar, P.1    Rose, M.2    Singh, M.3
  • 7
    • 16644377741 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome
    • DOI 10.1097/01.ASN.0000139067.83419.46
    • Guan Y. Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome. J Am Soc Nephrol 2004; 15:2801-2815. (Pubitemid 41103389)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.11 , pp. 2801-2815
    • Guan, Y.1
  • 8
    • 44349111879 scopus 로고    scopus 로고
    • PPARs and female reproduction: Evidence from genetically manipulated mice
    • Yang J, Chen L, Zhang X, et al. PPARs and female reproduction: evidence from genetically manipulated mice. PPAR Res 2008; 2008:723243.
    • (2008) PPAR Res , vol.2008 , pp. 723243
    • Yang, J.1    Chen, L.2    Zhang, X.3
  • 9
    • 45149134035 scopus 로고    scopus 로고
    • PPARs and the kidney in metabolic syndrome
    • Ruan X, Zheng F, Guan Y. PPARs and the kidney in metabolic syndrome. Am J Physiol Renal Physiol 2008; 294:1032-1047.
    • (2008) Am J Physiol Renal Physiol , vol.294 , pp. 1032-1047
    • Ruan, X.1    Zheng, F.2    Guan, Y.3
  • 10
    • 36249006990 scopus 로고    scopus 로고
    • Rosiglitazone decreases albuminuria in type 2 diabetic patients
    • DOI 10.1038/sj.ki.5002516, PII 5002516
    • Miyazaki Y, Cersosimo E, Triplitt C, DeFronzo RA. Rosiglitazone decreases albuminuria in type 2 diabetic patients. Kidney Int 2007; 72:1367-1373. (Pubitemid 350126770)
    • (2007) Kidney International , vol.72 , Issue.11 , pp. 1367-1373
    • Miyazaki, Y.1    Cersosimo, E.2    Triplitt, C.3    DeFronzo, R.A.4
  • 11
    • 79957815267 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptoralpha is renoprotective in doxorubicin-induced glomerular injury
    • Zhou Y, Kong X, Zhao P, et al. Peroxisome proliferator-activated receptoralpha is renoprotective in doxorubicin-induced glomerular injury. Kidney Int 2011; 79:1302-1311.
    • (2011) Kidney Int , vol.79 , pp. 1302-1311
    • Zhou, Y.1    Kong, X.2    Zhao, P.3
  • 12
    • 0028015713 scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) γ: Adipose-predominant expression and induction early in adipocyte differentiation
    • DOI 10.1210/en.135.2.798
    • Chawla A, Schwarz EJ, Dimaculangan DD, Lazar MA. Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation. Endocrinology 1994; 135:798-800. (Pubitemid 24241266)
    • (1994) Endocrinology , vol.135 , Issue.2 , pp. 798-800
    • Chawla, A.1    Schwarz, E.J.2    Dimaculangan, D.D.3    Lazar, M.A.4
  • 13
    • 0035658541 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature
    • Guan Y, Zhang Y, Schneider A, et al. Peroxisome proliferator-activated receptor-gamma activity is associated with renal microvasculature. Am J Physiol Renal Physiol 2001; 281:1036-1046.
    • (2001) Am J Physiol Renal Physiol , vol.281 , pp. 1036-1046
    • Guan, Y.1    Zhang, Y.2    Schneider, A.3
  • 15
    • 0031408955 scopus 로고    scopus 로고
    • Expression of peroxisome proliferatoractivated receptors in urinary tract of rabbits and humans
    • Guan Y, Zhang Y, Davis L, Breyer MD. Expression of peroxisome proliferatoractivated receptors in urinary tract of rabbits and humans. Am J Physiol 1997; 273:1013-1022.
    • (1997) Am J Physiol , vol.273 , pp. 1013-1022
    • Guan, Y.1    Zhang, Y.2    Davis, L.3    Breyer, M.D.4
  • 16
    • 0033387870 scopus 로고    scopus 로고
    • Expression of peroxisomal proliferatoractivated receptors and retinoid X receptors in the kidney
    • Yang T, Michele DE, Park J, et al. Expression of peroxisomal proliferatoractivated receptors and retinoid X receptors in the kidney. Am J Physiol 1999; 277:966-973.
    • (1999) Am J Physiol , vol.277 , pp. 966-973
    • Yang, T.1    Michele, D.E.2    Park, J.3
  • 17
    • 0035098304 scopus 로고    scopus 로고
    • Expression and function of peroxisome proliferator-activated receptor-γ in mesangial cells
    • Nicholas SB, Kawano Y, Wakino S, et al. Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells. Hypertension 2001; 37:722-727. (Pubitemid 32199056)
    • (2001) Hypertension , vol.37 , Issue.2 , pp. 722-727
    • Nicholas, S.B.1    Kawano, Y.2    Wakino, S.3    Collins, A.R.4    Hsueh, W.A.5
  • 20
    • 0037302877 scopus 로고    scopus 로고
    • Differential, inducible gene targeting in renal epithelia, vascular endothelium, and viscera of Mx1Cre mice
    • Schneider A, Zhang Y, Guan Y, et al. Differential, inducible gene targeting in renal epithelia, vascular endothelium, and viscera of Mx1Cre mice. Am J Physiol Renal Physiol 2003; 284:411-417.
    • (2003) Am J Physiol Renal Physiol , vol.284 , pp. 411-417
    • Schneider, A.1    Zhang, Y.2    Guan, Y.3
  • 21
    • 37549040896 scopus 로고    scopus 로고
    • Ferulic acid prevents pathological and functional abnormalities of the kidney in Otsuka Long-Evans Tokushima Fatty diabetic rats
    • Fujita A, Sasaki H, Doi A, et al. Ferulic acid prevents pathological and functional abnormalities of the kidney in Otsuka Long-Evans Tokushima Fatty diabetic rats. Diabetes Res Clin Pract 2008; 79:11-17.
    • (2008) Diabetes Res Clin Pract , vol.79 , pp. 11-17
    • Fujita, A.1    Sasaki, H.2    Doi, A.3
  • 22
    • 60549085974 scopus 로고    scopus 로고
    • Role of PPARgamma in renoprotection in type 2 diabetes: Molecular mechanisms and therapeutic potential
    • Yang J, Zhang D, Li J, et al. Role of PPARgamma in renoprotection in type 2 diabetes: molecular mechanisms and therapeutic potential. Clin Sci (Lond) 2009; 116:17-26.
    • (2009) Clin Sci (Lond) , vol.116 , pp. 17-26
    • Yang, J.1    Zhang, D.2    Li, J.3
  • 24
    • 21344466513 scopus 로고    scopus 로고
    • Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients
    • DOI 10.2337/diabetes.54.7.2206
    • Pistrosch F, Herbrig K, Kindel B, et al. Rosiglitazone improves glomerular hyperfiltration, renal endothelial dysfunction, and microalbuminuria of incipient diabetic nephropathy in patients. Diabetes 2005; 54:2206-2211. (Pubitemid 40911285)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 2206-2211
    • Pistrosch, F.1    Herbrig, K.2    Kindel, B.3    Passauer, J.4    Fischer, S.5    Gross, P.6
  • 25
    • 67349188030 scopus 로고    scopus 로고
    • Emerging role of PPAR ligands in the management of diabetic nephropathy
    • Balakumar P, Arora MK, Singh M. Emerging role of PPAR ligands in the management of diabetic nephropathy. Pharmacol Res 2009; 60:170-173.
    • (2009) Pharmacol Res , vol.60 , pp. 170-173
    • Balakumar, P.1    Arora, M.K.2    Singh, M.3
  • 26
    • 77954957730 scopus 로고    scopus 로고
    • The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats
    • Flaquer M, Lloberas N, Franquesa M, et al. The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats. Life Sci 2010; 87:147-153.
    • (2010) Life Sci , vol.87 , pp. 147-153
    • Flaquer, M.1    Lloberas, N.2    Franquesa, M.3
  • 27
    • 74249088976 scopus 로고    scopus 로고
    • Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients
    • Liu L, Zheng T, Wang F, et al. Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetic patients. Diabetes Care 2010; 33:144-149.
    • (2010) Diabetes Care , vol.33 , pp. 144-149
    • Liu, L.1    Zheng, T.2    Wang, F.3
  • 28
  • 30
    • 78650286735 scopus 로고    scopus 로고
    • The nuclear hormone receptor PPARgamma as a therapeutic target in major diseases
    • Schmidt MV, Brune B, von Knethen A. The nuclear hormone receptor PPARgamma as a therapeutic target in major diseases. ScientificWorld-Journal 2010; 10:2181-2197.
    • (2010) Scientific World-Journal , vol.10 , pp. 2181-2197
    • Schmidt, M.V.1    Brune, B.2    Von Knethen, A.3
  • 31
    • 79955692835 scopus 로고    scopus 로고
    • A role for central nervous system PPARgamma in the regulation of energy balance
    • Ryan KK, Li B, Grayson BE, et al. A role for central nervous system PPARgamma in the regulation of energy balance. Nat Med 2011; 17:623-626.
    • (2011) Nat Med , vol.17 , pp. 623-626
    • Ryan, K.K.1    Li, B.2    Grayson, B.E.3
  • 33
    • 77954589084 scopus 로고    scopus 로고
    • PPARs in the renal regulation of systemic blood pressure
    • Roszer T, Ricote M. PPARs in the renal regulation of systemic blood pressure. PPAR Res 2010; 2010:698730.
    • (2010) PPAR Res , vol.2010 , pp. 698730
    • Roszer, T.1    Ricote, M.2
  • 34
    • 79953027322 scopus 로고    scopus 로고
    • Transcriptional up-regulation of antioxidant genes by PPARdelta inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells
    • Kim HJ, Ham SA, Paek KS, et al. Transcriptional up-regulation of antioxidant genes by PPARdelta inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells. Biochem Biophys Res Commun 2011; 406:564-569.
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 564-569
    • Kim, H.J.1    Ham, S.A.2    Paek, K.S.3
  • 35
    • 35848935619 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ is involved in the control of renin gene expression
    • DOI 10.1161/HYPERTENSIONAHA.107.092817, PII 0000426820071100000022
    • Todorov VT, Desch M, Schmitt-Nilson N, et al. Peroxisome proliferatoractivated receptor-gamma is involved in the control of renin gene expression. Hypertension 2007; 50:939-944. (Pubitemid 350287538)
    • (2007) Hypertension , vol.50 , Issue.5 , pp. 939-944
    • Todorov, V.T.1    Desch, M.2    Schmitt-Nilson, N.3    Todorova, A.4    Kurtz, A.5
  • 36
    • 50449108231 scopus 로고    scopus 로고
    • The Pal3 promoter sequence is critical for the regulation of human renin gene transcription by peroxisome proliferator-activated receptor-gamma
    • Todorov VT, Desch M, Schubert T, Kurtz A. The Pal3 promoter sequence is critical for the regulation of human renin gene transcription by peroxisome proliferator-activated receptor-gamma. Endocrinology 2008; 149:4647-4657.
    • (2008) Endocrinology , vol.149 , pp. 4647-4657
    • Todorov, V.T.1    Desch, M.2    Schubert, T.3    Kurtz, A.4
  • 38
    • 78649384431 scopus 로고    scopus 로고
    • Effects of PPARgamma on hypertension, atherosclerosis, and chronic kidney disease
    • Sugawara A, Uruno A, Kudo M, et al. Effects of PPARgamma on hypertension, atherosclerosis, and chronic kidney disease. Endocr J 2010; 57:847-852.
    • (2010) Endocr J , vol.57 , pp. 847-852
    • Sugawara, A.1    Uruno, A.2    Kudo, M.3
  • 39
    • 77149177984 scopus 로고    scopus 로고
    • Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells
    • Desch M, Schreiber A, Schweda F, et al. Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells. Hypertension 2010; 55:660-666.
    • (2010) Hypertension , vol.55 , pp. 660-666
    • Desch, M.1    Schreiber, A.2    Schweda, F.3
  • 40
    • 62749196172 scopus 로고    scopus 로고
    • Distinct functions of vascular endothelial and smooth muscle PPARgamma in regulation of blood pressure and vascular tone
    • Wang N, Symons JD, Zhang H, et al. Distinct functions of vascular endothelial and smooth muscle PPARgamma in regulation of blood pressure and vascular tone. Toxicol Pathol 2009; 37:21-27.
    • (2009) Toxicol Pathol , vol.37 , pp. 21-27
    • Wang, N.1    Symons, J.D.2    Zhang, H.3
  • 41
    • 4744340732 scopus 로고    scopus 로고
    • Impact of genetic variation of PPARγ in humans
    • DOI 10.1016/j.ymgme.2004.08.014, PII S1096719204002239, ASHG 2004 Meeting Toronto
    • Meirhaeghe A, Amouyel P. Impact of genetic variation of PPARgamma in humans. Mol Genet Metab 2004; 83:93-102. (Pubitemid 39311284)
    • (2004) Molecular Genetics and Metabolism , vol.83 , Issue.1-2 , pp. 93-102
    • Meirhaeghe, A.1    Amouyel, P.2
  • 43
    • 34547445697 scopus 로고    scopus 로고
    • PPAR-γ activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats
    • DOI 10.1159/000104834
    • Efrati S, Berman S, Ilgiyeav E, et al. PPAR-gamma activation inhibits angiotensin II synthesis, apoptosis, and proliferation of mesangial cells from spontaneously hypertensive rats. Nephron Exp Nephrol 2007; 106:e107-e112. (Pubitemid 47165837)
    • (2007) Nephron - Experimental Nephrology , vol.106 , Issue.4
    • Efrati, S.1    Berman, S.2    Ilgiyeav, E.3    Averbukh, Z.4    Weissgarten, J.5
  • 44
    • 34547232484 scopus 로고    scopus 로고
    • Appropriate blood pressure control in hypertensive and normotensive type 2 diabetes mellitus: A summary of the ABCD trial
    • DOI 10.1038/ncpneph0559, PII NCPNEPH0559
    • Schrier RW, Estacio RO, Mehler PS, Hiatt WR. Appropriate blood pressure control in hypertensive and normotensive type 2 diabetes mellitus: a summary of the ABCD trial. Nat Clin Pract Nephrol 2007; 3:428-438. (Pubitemid 47123588)
    • (2007) Nature Clinical Practice Nephrology , vol.3 , Issue.8 , pp. 428-438
    • Schrier, R.W.1    Estacio, R.O.2    Mehler, P.S.3    Hiatt, W.R.4
  • 45
    • 33748654394 scopus 로고    scopus 로고
    • Klinische und gesundheitsökonomische auswirkungen einer frühen irbesartan-therapie bei typ-2-diabetes, hypertonie und nierenerkrankung
    • DOI 10.1055/s-2006-947822
    • Palmer AJ, Roze S, Rodby RA, et al. Clinical and health economic implications of early treatment with irbesartan of patients with type 2 diabetes mellitus, hypertension and nephropathy. Dtsch Med Wochenschr 2006; 131:1721-1726. (Pubitemid 44532020)
    • (2006) Deutsche Medizinische Wochenschrift , vol.131 , Issue.31-32 , pp. 1721-1726
    • Palmer, A.J.1    Roze, S.2    Rodby, R.A.3    Valentine, W.J.4    Ritz, E.5    Lehnert, H.6
  • 46
    • 0027943541 scopus 로고
    • In situ characterization of renal insulin receptors in the rat
    • Sechi LA, De Carli S, Bartoli E. In situ characterization of renal insulin receptors in the rat. J Recept Res 1994; 14:347-356. (Pubitemid 24376634)
    • (1994) Journal of Receptor Research , vol.14 , Issue.6-8 , pp. 347-356
    • Sechi, L.A.1    De Carli, S.2    Bartoli, E.3
  • 51
    • 0037498046 scopus 로고    scopus 로고
    • Angiotensin II blockade restores albumin reabsorption in the proximal tubules of diabetic rats
    • DOI 10.1291/hypres.26.413
    • Tojo A, Onozato ML, Kurihara H, et al. Angiotensin II blockade restores albumin reabsorption in the proximal tubules of diabetic rats. Hypertens Res 2003; 26:413-419. (Pubitemid 36701683)
    • (2003) Hypertension Research , vol.26 , Issue.5 , pp. 413-419
    • Tojo, A.1    Onozato, M.L.2    Kurihara, H.3    Sakai, T.4    Goto, A.5    Fujita, T.6
  • 52
    • 59649089653 scopus 로고    scopus 로고
    • Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor-and insulinmediated signaling cross talk
    • Hosojima M, Sato H, Yamamoto K, et al. Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor-and insulinmediated signaling cross talk. Endocrinology 2009; 150:871-878.
    • (2009) Endocrinology , vol.150 , pp. 871-878
    • Hosojima, M.1    Sato, H.2    Yamamoto, K.3
  • 53
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkβ
    • DOI 10.1126/science.1061620
    • Yuan M, Konstantopoulos N, Lee J, et al. Reversal of obesity-and dietinduced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science 2001; 293:1673-1677. (Pubitemid 32807849)
    • (2001) Science , vol.293 , Issue.5535 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3    Hansen, L.4    Li, Z.-W.5    Karin, M.6    Shoelson, S.E.7
  • 54
    • 0037414811 scopus 로고    scopus 로고
    • Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)- and tumor necrosis factor α (TNFα)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells
    • DOI 10.1074/jbc.M205565200
    • Jiang G, Dallas-Yang Q, Liu F, et al. Salicylic acid reverses phorbol 12-myristate-13-acetate (PMA)-and tumor necrosis factor alpha (TNFalpha)-induced insulin receptor substrate 1 (IRS1) serine 307 phosphorylation and insulin resistance in human embryonic kidney 293 (HEK293) cells. J Biol Chem 2003; 278:180-186. (Pubitemid 36043560)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.1 , pp. 180-186
    • Jiang, G.1    Dallas-Yang, Q.2    Liu, F.3    Moller, D.E.4    Zhang, B.B.5
  • 58
    • 33947279878 scopus 로고    scopus 로고
    • Rosiglitazone prevents advanced glycation end products-induced renal toxicity likely through suppression of plasminogen activator inhibitor-1
    • DOI 10.1093/toxsci/kfm010
    • Yu X, Li C, Li X, Cai L. Rosiglitazone prevents advanced glycation end products-induced renal toxicity likely through suppression of plasminogen activator inhibitor-1. Toxicol Sci 2007; 96:346-356. (Pubitemid 46432031)
    • (2007) Toxicological Sciences , vol.96 , Issue.2 , pp. 346-356
    • Yu, X.1    Li, C.2    Li, X.3    Cai, L.4
  • 59
    • 77954155906 scopus 로고    scopus 로고
    • Advanced glycation end products-induced apoptosis attenuated by PPARdelta activation and epigallocatechin gallate through NF-kappaB pathway in human embryonic kidney cells and human mesangial cells
    • Liang YJ, Jian JH, Liu YC, et al. Advanced glycation end products-induced apoptosis attenuated by PPARdelta activation and epigallocatechin gallate through NF-kappaB pathway in human embryonic kidney cells and human mesangial cells. Diabetes Metab Res Rev 2010; 26:406-416.
    • (2010) Diabetes Metab Res Rev , vol.26 , pp. 406-416
    • Liang, Y.J.1    Jian, J.H.2    Liu, Y.C.3
  • 60
    • 77953693954 scopus 로고    scopus 로고
    • Advanced glycation end products inhibit Na+ K+ ATPase in proximal tubule epithelial cells: Role of cytosolic phospholipase A2alpha and phosphatidylinositol 4-phosphate 5-kinase gamma
    • Gallicchio MA, Bach LA. Advanced glycation end products inhibit Na+ K+ ATPase in proximal tubule epithelial cells: role of cytosolic phospholipase A2alpha and phosphatidylinositol 4-phosphate 5-kinase gamma. Biochim Biophys Acta 2010; 1803:919-930.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 919-930
    • Gallicchio, M.A.1    Bach, L.A.2
  • 62
    • 77955052182 scopus 로고    scopus 로고
    • Nifedipine inhibits advanced glycation end products (AGEs) and their receptor (RAGE) interactionmediated proximal tubular cell injury via peroxisome proliferator-activated receptor-gamma activation
    • Matsui T, Yamagishi S, Takeuchi M, et al. Nifedipine inhibits advanced glycation end products (AGEs) and their receptor (RAGE) interactionmediated proximal tubular cell injury via peroxisome proliferator-activated receptor-gamma activation. Biochem Biophys Res Commun 2010; 398:326-330.
    • (2010) Biochem Biophys Res Commun , vol.398 , pp. 326-330
    • Matsui, T.1    Yamagishi, S.2    Takeuchi, M.3
  • 63
    • 34547884217 scopus 로고    scopus 로고
    • Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-γ, activation
    • Matsui T, Yamagishi S, Ueda S, et al. Telmisartan, an angiotensin II type 1 receptor blocker, inhibits advanced glycation end-product (AGE)-induced monocyte chemoattractant protein-1 expression in mesangial cells through downregulation of receptor for AGEs via peroxisome proliferator-activated receptor-gamma activation. J Int Med Res 2007; 35:482-489. (Pubitemid 47261110)
    • (2007) Journal of International Medical Research , vol.35 , Issue.4 , pp. 482-489
    • Matsui, T.1    Yamagishi, S.2    Ueda, S.3    Nakamura, K.4    Imaizumi, T.5    Takeuchi, M.6    Inoue, H.7
  • 64
    • 33644650299 scopus 로고    scopus 로고
    • Inflammation and dyslipidemia in nephropathy: An epidemiologic perspective
    • DOI 10.1038/sj.ki.5000111, PII 5000111
    • Seliger SL. Inflammation and dyslipidemia in nephropathy: an epidemiologic perspective. Kidney Int 2006; 69:206-208. (Pubitemid 43323067)
    • (2006) Kidney International , vol.69 , Issue.2 , pp. 206-208
    • Seliger, S.L.1
  • 65
    • 58149127646 scopus 로고    scopus 로고
    • PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta
    • Kawai T, Masaki T, Doi S, et al. PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta. Lab Invest 2009; 89:47-58.
    • (2009) Lab Invest , vol.89 , pp. 47-58
    • Kawai, T.1    Masaki, T.2    Doi, S.3
  • 67
    • 34147213227 scopus 로고    scopus 로고
    • Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation
    • Ohga S, Shikata K, Yozai K, et al. Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation. Am J Physiol Renal Physiol 2007; 292:1141-1150.
    • (2007) Am J Physiol Renal Physiol , vol.292 , pp. 1141-1150
    • Ohga, S.1    Shikata, K.2    Yozai, K.3
  • 68
    • 33646945290 scopus 로고    scopus 로고
    • Activation of tubular epithelial cells in diabetic nephropathy and the role of the peroxisome proliferator-activated receptor-γ agonist
    • DOI 10.1681/ASN.2005101113
    • Tang SC, Leung JC, Chan LY, et al. Activation of tubular epithelial cells in diabetic nephropathy and the role of the peroxisome proliferator-activated receptor-gamma agonist. J Am Soc Nephrol 2006; 17:1633-1643. (Pubitemid 43794666)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.6 , pp. 1633-1643
    • Tang, S.C.W.1    Leung, J.C.K.2    Chan, L.Y.Y.3    Tsang, A.W.L.4    Lai, K.N.5
  • 71
    • 35848956112 scopus 로고    scopus 로고
    • Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production
    • DOI 10.1681/ASN.2006080895
    • Prabhakar S, Starnes J, Shi S, et al. Diabetic nephropathy is associated with oxidative stress and decreased renal nitric oxide production. J Am Soc Nephrol 2007; 18:2945-2952. (Pubitemid 350058402)
    • (2007) Journal of the American Society of Nephrology , vol.18 , Issue.11 , pp. 2945-2952
    • Prabhakar, S.1    Starnes, J.2    Shi, S.3    Lonis, B.4    Tran, R.5
  • 72
    • 34447545820 scopus 로고    scopus 로고
    • Rosiglitazone increases PPARγ in renal tubular epithelial cells and protects against damage by hydrogen peroxide
    • DOI 10.1159/000105125
    • Sommer M, Wolf G. Rosiglitazone increases PPARgamma in renal tubular epithelial cells and protects against damage by hydrogen peroxide. Am J Nephrol 2007; 27:425-434. (Pubitemid 47077207)
    • (2007) American Journal of Nephrology , vol.27 , Issue.4 , pp. 425-434
    • Sommer, M.1    Wolf, G.2
  • 73
    • 33744987670 scopus 로고    scopus 로고
    • Amelioration of age-related inflammation and oxidative stress by PPARγ activator: Suppression of NF-κB by 2,4-thiazolidinedione
    • DOI 10.1016/j.exger.2006.04.005, PII S0531556506001033
    • Sung B, Park S, Yu BP, Chung HY. Amelioration of age-related inflammation and oxidative stress by PPARgamma activator: suppression of NF-kappaB by 2,4-thiazolidinedione. Exp Gerontol 2006; 41:590-599. (Pubitemid 43867228)
    • (2006) Experimental Gerontology , vol.41 , Issue.6 , pp. 590-599
    • Sung, B.1    Park, S.2    Yu, B.P.3    Chung, H.Y.4
  • 74
    • 77952674092 scopus 로고    scopus 로고
    • The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy
    • Arora MK, Reddy K, Balakumar P. The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy. Eur J Pharmacol 2010; 636:137-144.
    • (2010) Eur J Pharmacol , vol.636 , pp. 137-144
    • Arora, M.K.1    Reddy, K.2    Balakumar, P.3
  • 75
    • 34248187069 scopus 로고    scopus 로고
    • Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease
    • DOI 10.2337/db06-0506
    • Menzaghi C, Trischitta V, Doria A. Genetic influences of adiponectin on insulin resistance, type 2 diabetes, and cardiovascular disease. Diabetes 2007; 56:1198-1209. (Pubitemid 46715598)
    • (2007) Diabetes , vol.56 , Issue.5 , pp. 1198-1209
    • Menzaghi, C.1    Trischitta, V.2    Doria, A.3
  • 76
    • 79751529070 scopus 로고    scopus 로고
    • Cytokines in the progression of pancreatic betacell dysfunction
    • Wang C, Guan Y, Yang J. Cytokines in the progression of pancreatic betacell dysfunction. Int J Endocrinol 2010; 2010:515136.
    • (2010) Int J Endocrinol , vol.2010 , pp. 515136
    • Wang, C.1    Guan, Y.2    Yang, J.3
  • 80
    • 70349242253 scopus 로고    scopus 로고
    • Inhibitory effects of adiponectin on platelet-derived growth factor-induced mesangial cell migration
    • Ishizawa K, Dorjsuren N, Izawa-Ishizawa Y, et al. Inhibitory effects of adiponectin on platelet-derived growth factor-induced mesangial cell migration. J Endocrinol 2009; 202:309-316.
    • (2009) J Endocrinol , vol.202 , pp. 309-316
    • Ishizawa, K.1    Dorjsuren, N.2    Izawa-Ishizawa, Y.3
  • 81
    • 33847330122 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on plasma adiponectin and renal adiponectin receptors in streptozotocin-induced diabetic rats
    • DOI 10.1016/j.ejphar.2006.11.066, PII S001429990601394X
    • Guo Z, Zhao Z. Effect of N-acetylcysteine on plasma adiponectin and renal adiponectin receptors in streptozotocin-induced diabetic rats. Eur J Pharmacol 2007; 558:208-213. (Pubitemid 46328886)
    • (2007) European Journal of Pharmacology , vol.558 , Issue.1-3 , pp. 208-213
    • Guo, Z.1    Zhao, Z.2
  • 82
    • 79958774013 scopus 로고    scopus 로고
    • Adiponectin reduces proteinuria in streptozotocin-induced diabetic Wistar rats
    • Nakamaki S, Satoh H, Kudoh A, et al. Adiponectin reduces proteinuria in streptozotocin-induced diabetic Wistar rats. Exp Biol Med (Maywood) 2011; 236:614-620.
    • (2011) Exp Biol Med (Maywood) , vol.236 , pp. 614-620
    • Nakamaki, S.1    Satoh, H.2    Kudoh, A.3
  • 83
    • 77954616530 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptorgamma increases adiponectin secretion via transcriptional repression of endoplasmic reticulum chaperone protein ERp44
    • Long Q, Lei T, Feng B, et al. Peroxisome proliferator-activated receptorgamma increases adiponectin secretion via transcriptional repression of endoplasmic reticulum chaperone protein ERp44. Endocrinology 2010; 151:3195-3203.
    • (2010) Endocrinology , vol.151 , pp. 3195-3203
    • Long, Q.1    Lei, T.2    Feng, B.3
  • 84
    • 79955939296 scopus 로고    scopus 로고
    • A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of nonalcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance
    • Zheng H, Li S, Ma L, et al. A novel agonist of PPAR-gamma based on barbituric acid alleviates the development of nonalcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance. Eur J Pharmacol 2011; 659:244-251.
    • (2011) Eur J Pharmacol , vol.659 , pp. 244-251
    • Zheng, H.1    Li, S.2    Ma, L.3
  • 85
    • 34547559826 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor α/γ dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice
    • DOI 10.2337/db06-1134
    • Cha DR, Zhang X, Zhang Y, et al. Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice. Diabetes 2007; 56:2036-2045. (Pubitemid 47195832)
    • (2007) Diabetes , vol.56 , Issue.8 , pp. 2036-2045
    • Dae, R.C.1    Zhang, X.2    Zhang, Y.3    Wu, J.4    Su, D.5    Jee, Y.H.6    Fang, X.7    Yu, B.8    Breyer, M.D.9    Guan, Y.10
  • 86
    • 56349100160 scopus 로고    scopus 로고
    • Adiponectin stimulates phosphorylation of AMP-activated protein kinase alpha in renal glomeruli
    • Cammisotto PG, Bendayan M. Adiponectin stimulates phosphorylation of AMP-activated protein kinase alpha in renal glomeruli. J Mol Histol 2008; 39:579-584.
    • (2008) J Mol Histol , vol.39 , pp. 579-584
    • Cammisotto, P.G.1    Bendayan, M.2
  • 87
    • 77951581118 scopus 로고    scopus 로고
    • Role of the energy sensor AMP-activated protein kinase in renal physiology and disease
    • Hallows KR, Mount PF, Pastor-Soler NM, Power DA. Role of the energy sensor AMP-activated protein kinase in renal physiology and disease. Am J Physiol Renal Physiol 2010; 298:1067-1077.
    • (2010) Am J Physiol Renal Physiol , vol.298 , pp. 1067-1077
    • Hallows, K.R.1    Mount, P.F.2    Pastor-Soler, N.M.3    Power, D.A.4
  • 88
    • 67649874800 scopus 로고    scopus 로고
    • The link between obesity and albuminuria: Adiponectin and podocyte dysfunction
    • Sharma K. The link between obesity and albuminuria: adiponectin and podocyte dysfunction. Kidney Int 2009; 76:145-148.
    • (2009) Kidney Int , vol.76 , pp. 145-148
    • Sharma, K.1
  • 89
    • 33644664433 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR)α activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: Comparison of activation of PPARα, PPARγ, and their combination
    • DOI 10.2337/diabetes.54.12.3358
    • Tsuchida A, Yamauchi T, Takekawa S, et al. Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination. Diabetes 2005; 54:3358-3370. (Pubitemid 43334324)
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3358-3370
    • Tsuchida, A.1    Yamauchi, T.2    Takekawa, S.3    Hada, Y.4    Ito, Y.5    Maki, T.6    Kadowaki, T.7
  • 91
    • 35348814384 scopus 로고    scopus 로고
    • Antioxidants attenuate high glucoseinduced hypertrophic growth in renal tubular epithelial cells
    • Huang JS, Chuang LY, Guh JY, et al. Antioxidants attenuate high glucoseinduced hypertrophic growth in renal tubular epithelial cells. Am J Physiol Renal Physiol 2007; 293:1072-1082.
    • (2007) Am J Physiol Renal Physiol , vol.293 , pp. 1072-1082
    • Huang, J.S.1    Chuang, L.Y.2    Guh, J.Y.3
  • 92
    • 0031801448 scopus 로고    scopus 로고
    • The cyclin kinase inhibitor p21WAF1, CIP1 is increased in experimental diabetic nephropathy: Potential role in glomerular hypertrophy
    • Kuan CJ, al-Douahji M, Shankland SJ. The cyclin kinase inhibitor p21WAF1, CIP1 is increased in experimental diabetic nephropathy: potential role in glomerular hypertrophy. J Am Soc Nephrol 1998; 9:986-993.
    • (1998) J Am Soc Nephrol , vol.9 , pp. 986-993
    • Kuan, C.J.1    Al-Douahji, M.2    Shankland, S.J.3
  • 95
    • 78751581941 scopus 로고    scopus 로고
    • Additive effect of PPAR-gamma agonist and ARB in treatment of experimental IgA nephropathy
    • Lai KN, Chan LY, Guo H, et al. Additive effect of PPAR-gamma agonist and ARB in treatment of experimental IgA nephropathy. Pediatr Nephrol 2011; 26:257-266.
    • (2011) Pediatr Nephrol , vol.26 , pp. 257-266
    • Lai, K.N.1    Chan, L.Y.2    Guo, H.3
  • 96
    • 79551564896 scopus 로고    scopus 로고
    • A PPARgamma agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR intracellular signaling
    • Yuan Y, Zhang A, Huang S, et al. A PPARgamma agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR intracellular signaling. Am J Physiol Renal Physiol 2011; 300:393-402.
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. 393-402
    • Yuan, Y.1    Zhang, A.2    Huang, S.3
  • 97
    • 67349274964 scopus 로고    scopus 로고
    • Emodin suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose
    • Li X, Liu W, Wang Q, et al. Emodin suppresses cell proliferation and fibronectin expression via p38MAPK pathway in rat mesangial cells cultured under high glucose. Mol Cell Endocrinol 2009; 307:157-162.
    • (2009) Mol Cell Endocrinol , vol.307 , pp. 157-162
    • Li, X.1    Liu, W.2    Wang, Q.3
  • 98
    • 33745698362 scopus 로고    scopus 로고
    • Hyperglycemia and glucosamine-induced mesangial cell cycle arrest and hypertrophy: Common or independent mechanisms?
    • DOI 10.1080/15216540600755980, PII K1697266WNU166K6
    • Masson E, Lagarde M, Wiernsperger N, El Bawab S. Hyperglycemia and glucosamine-induced mesangial cell cycle arrest and hypertrophy: common or independent mechanisms? IUBMB Life 2006; 58:381-388. (Pubitemid 43995622)
    • (2006) IUBMB Life , vol.58 , Issue.7 , pp. 381-388
    • Masson, E.1    Lagarde, M.2    Wiernsperger, N.3    El Bawab, S.4
  • 99
  • 100
    • 34548310417 scopus 로고    scopus 로고
    • Fibrillogenic amylin evokes the apoptosis of human mesangial cells
    • DOI 10.1016/j.diabres.2007.02.018, PII S0168822707001234
    • Peng A, Liu ZH, Zhou H, et al. Fibrillogenic amylin evokes the apoptosis of human mesangial cells. Diabetes Res Clin Pract 2007; 78:16-22. (Pubitemid 47348152)
    • (2007) Diabetes Research and Clinical Practice , vol.78 , Issue.1 , pp. 16-22
    • Peng, A.1    Liu, Z.-H.2    Zhou, H.3    Zhu, M.-Y.4    Li, L.-S.5
  • 101
    • 0034928022 scopus 로고    scopus 로고
    • Effect of insulin, proinsulin, and amylin on renin released from perfused rat kidney
    • DOI 10.1053/meta.2001.24200
    • Ikeda T, Iwata K, Ochi H. Effect of insulin, proinsulin, and amylin on renin release from perfused rat kidney. Metabolism 2001; 50:763-766. (Pubitemid 32700453)
    • (2001) Metabolism: Clinical and Experimental , vol.50 , Issue.7 , pp. 763-766
    • Ikeda, T.1    Iwata, K.2    Ochi, H.3
  • 102
    • 0345355157 scopus 로고    scopus 로고
    • Interaction of the renal amylin and renin-angiotensin systems in animal models of diabetes and hypertension
    • DOI 10.1159/000057400
    • Wookey PJ, Cao Z, Cooper ME. Interaction of the renal amylin and reninangiotensin systems in animal models of diabetes and hypertension. Miner Electrolyte Metab 1998; 24:389-399. (Pubitemid 29056249)
    • (1998) Mineral and Electrolyte Metabolism , vol.24 , Issue.6 , pp. 389-399
    • Wookey, P.J.1    Cao, Z.2    Cooper, M.E.3
  • 103
    • 21344471091 scopus 로고    scopus 로고
    • Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide
    • DOI 10.2337/diabetes.54.7.2235
    • Hull RL, Shen ZP, Watts MR, et al. Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide. Diabetes 2005; 54:2235-2244. (Pubitemid 40911289)
    • (2005) Diabetes , vol.54 , Issue.7 , pp. 2235-2244
    • Hull, R.L.1    Shen, Z.-P.2    Watts, M.R.3    Kodama, K.4    Carr, D.B.5    Utzschneider, K.M.6    Zraika, S.7    Wang, F.8    Kahn, S.E.9
  • 104
    • 77956391365 scopus 로고    scopus 로고
    • Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats
    • Dai B, Liu Y, Mei C, et al. Rosiglitazone attenuates development of polycystic kidney disease and prolongs survival in Han:SPRD rats. Clin Sci (Lond) 2010; 119:323-333.
    • (2010) Clin Sci (Lond) , vol.119 , pp. 323-333
    • Dai, B.1    Liu, Y.2    Mei, C.3
  • 105
    • 79952297525 scopus 로고    scopus 로고
    • Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis
    • Takiar V, Nishio S, Seo-Mayer P, et al. Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis. Proc Natl Acad Sci USA 2011; 108:2462-2467.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 2462-2467
    • Takiar, V.1    Nishio, S.2    Seo-Mayer, P.3
  • 106
    • 33745869049 scopus 로고    scopus 로고
    • Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
    • LeBrasseur NK, Kelly M, Tsao TS, et al. Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues. Am J Physiol Endocrinol Metab 2006; 291:175-181.
    • (2006) Am J Physiol Endocrinol Metab , vol.291 , pp. 175-181
    • Lebrasseur, N.K.1    Kelly, M.2    Tsao, T.S.3
  • 107
    • 77952284479 scopus 로고    scopus 로고
    • Rosiglitazone inhibits cell proliferation by inducing G1 cell cycle arrest and apoptosis in ADPKD cyst-lining epithelia cells
    • Liu Y, Dai B, Fu L, et al. Rosiglitazone inhibits cell proliferation by inducing G1 cell cycle arrest and apoptosis in ADPKD cyst-lining epithelia cells. Basic Clin Pharmacol Toxicol 2010; 106:523-530.
    • (2010) Basic Clin Pharmacol Toxicol , vol.106 , pp. 523-530
    • Liu, Y.1    Dai, B.2    Fu, L.3
  • 108
    • 79551566710 scopus 로고    scopus 로고
    • PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease
    • Yoshihara D, Kurahashi H, Morita M, et al. PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease. Am J Physiol Renal Physiol 2011; 300:465-474.
    • (2011) Am J Physiol Renal Physiol , vol.300 , pp. 465-474
    • Yoshihara, D.1    Kurahashi, H.2    Morita, M.3
  • 109
    • 78650772659 scopus 로고    scopus 로고
    • Pioglitazone attenuates cystic burden in the PCK rodent model of polycystic kidney disease
    • Blazer-Yost BL, Haydon J, Eggleston-Gulyas T, et al. Pioglitazone attenuates cystic burden in the PCK rodent model of polycystic kidney disease. PPAR Res 2010; 2010:274376.
    • (2010) PPAR Res , vol.2010 , pp. 274376
    • Blazer-Yost, B.L.1    Haydon, J.2    Eggleston-Gulyas, T.3
  • 110
    • 0242441640 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ C161T polymorphisms and survival of Japanese patients with immunoglobulin A nephropathy
    • DOI 10.1034/j.1399-0004.2003.00154.x
    • Song J, Sakatsume M, Narita I, et al. Peroxisome proliferator-activated receptor gamma C161T polymorphisms and survival of Japanese patients with immunoglobulin A nephropathy. Clin Genet 2003; 64:398-403. (Pubitemid 37406888)
    • (2003) Clinical Genetics , vol.64 , Issue.5 , pp. 398-403
    • Song, J.1    Sakatsume, M.2    Narita, I.3    Goto, S.4    Omori, K.5    Takada, T.6    Saito, N.7    Ueno, M.8    Gejyo, F.9
  • 111
    • 67649979340 scopus 로고    scopus 로고
    • Protective effect of peroxisome proliferatoractivated receptor-gamma agonists on activated renal proximal tubular epithelial cells in IgA nephropathy
    • Xiao J, Leung JC, Chan LY, et al. Protective effect of peroxisome proliferatoractivated receptor-gamma agonists on activated renal proximal tubular epithelial cells in IgA nephropathy. Nephrol Dial Transplant 2009; 24:2067-2077.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2067-2077
    • Xiao, J.1    Leung, J.C.2    Chan, L.Y.3
  • 112
    • 53049094210 scopus 로고    scopus 로고
    • BMP-7 protects mesangial cells from injury by polymeric IgA
    • Chan WL, Leung JC, Chan LY, et al. BMP-7 protects mesangial cells from injury by polymeric IgA. Kidney Int 2008; 74:1026-1039.
    • (2008) Kidney Int , vol.74 , pp. 1026-1039
    • Chan, W.L.1    Leung, J.C.2    Chan, L.Y.3
  • 113
    • 78650218509 scopus 로고    scopus 로고
    • Viewpoint: Why do we need a point-ofcare CD4 test for low-income countries?
    • Zachariah R, Reid SD, Chaillet P, et al. Viewpoint: why do we need a point-ofcare CD4 test for low-income countries? Trop Med Int Health 2011; 16:37-41.
    • (2011) Trop Med Int Health , vol.16 , pp. 37-41
    • Zachariah, R.1    Reid, S.D.2    Chaillet, P.3
  • 114
    • 33751012098 scopus 로고    scopus 로고
    • Vitamin e in renal therapeutic regiments
    • Thabet MA, Chan JC. Vitamin E in renal therapeutic regiments. Pediatr Nephrol 2006; 21:1790-1801.
    • (2006) Pediatr Nephrol , vol.21 , pp. 1790-1801
    • Thabet, M.A.1    Chan, J.C.2
  • 115
    • 79951933572 scopus 로고    scopus 로고
    • Vitamin e and adiponectin: Proposed mechanism for vitamin E-induced improvement in insulin sensitivity
    • Gray B, Swick J, Ronnenberg AG. Vitamin E and adiponectin: proposed mechanism for vitamin E-induced improvement in insulin sensitivity. Nutr Rev 2011; 69:155-161.
    • (2011) Nutr Rev , vol.69 , pp. 155-161
    • Gray, B.1    Swick, J.2    Ronnenberg, A.G.3
  • 116
    • 83055181037 scopus 로고    scopus 로고
    • Protective effects of PPAR{gamma} agonist in acute nephrotic syndrome
    • [Epub ahead of print]
    • Zuo Y, Yang HC, Potthoff SA, et al. Protective effects of PPAR{gamma} agonist in acute nephrotic syndrome. Nephrol Dial Transplant 2011. [Epub ahead of print]
    • (2011) Nephrol Dial Transplant
    • Zuo, Y.1    Yang, H.C.2    Potthoff, S.A.3
  • 117
    • 78549281454 scopus 로고    scopus 로고
    • Rosiglitazone, peroxisome proliferator receptor-gamma agonist, ameliorates gentamicin-induced nephrotoxicity in rats
    • Ozbek E, Ilbey YO, Simsek A, et al. Rosiglitazone, peroxisome proliferator receptor-gamma agonist, ameliorates gentamicin-induced nephrotoxicity in rats. Int Urol Nephrol 2010; 42:579-587.
    • (2010) Int Urol Nephrol , vol.42 , pp. 579-587
    • Ozbek, E.1    Ilbey, Y.O.2    Simsek, A.3
  • 118
    • 77950565531 scopus 로고    scopus 로고
    • Effect of rosiglitazone on cisplatin-induced nephrotoxicity
    • Ozkaya O, Yavuz O, Can B, et al. Effect of rosiglitazone on cisplatin-induced nephrotoxicity. Ren Fail 2010; 32:368-371.
    • (2010) Ren Fail , vol.32 , pp. 368-371
    • Ozkaya, O.1    Yavuz, O.2    Can, B.3
  • 119
    • 78650030818 scopus 로고    scopus 로고
    • Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPARgamma agonist actions
    • Arozal W, Watanabe K, Veeraveedu PT, et al. Telmisartan prevents the progression of renal injury in daunorubicin rats with the alteration of angiotensin II and endothelin-1 receptor expression associated with its PPARgamma agonist actions. Toxicology 2011; 279:91-99.
    • (2011) Toxicology , vol.279 , pp. 91-99
    • Arozal, W.1    Watanabe, K.2    Veeraveedu, P.T.3
  • 122
    • 34547629755 scopus 로고    scopus 로고
    • Protective effects of peroxisome proliferator-activated receptor γ ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury
    • DOI 10.1097/01.tp.0000269614.21367.3f, PII 0000789020070727000011
    • Doi S, Masaki T, Arakawa T, et al. Protective effects of peroxisome proliferator-activated receptor gamma ligand on apoptosis and hepatocyte growth factor induction in renal ischemia-reperfusion injury. Transplantation 2007; 84:207-213. (Pubitemid 47205754)
    • (2007) Transplantation , vol.84 , Issue.2 , pp. 207-213
    • Doi, S.1    Masaki, T.2    Arakawa, T.3    Takahashi, S.4    Kawai, T.5    Nakashima, A.6    Naito, T.7    Kohno, N.8    Yorioka, N.9
  • 123
    • 78650142241 scopus 로고    scopus 로고
    • The subtypes of peroxisome proliferator-activated receptors expressed by human podocytes and their role in decreasing podocyte injury
    • Miglio G, Rosa AC, Rattazzi L, et al. The subtypes of peroxisome proliferator-activated receptors expressed by human podocytes and their role in decreasing podocyte injury. Br J Pharmacol 2011; 162:111-125.
    • (2011) Br J Pharmacol , vol.162 , pp. 111-125
    • Miglio, G.1    Rosa, A.C.2    Rattazzi, L.3
  • 124
    • 72049124334 scopus 로고    scopus 로고
    • The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury
    • Yang HC, Deleuze S, Zuo Y, et al. The PPARgamma agonist pioglitazone ameliorates aging-related progressive renal injury. J Am Soc Nephrol 2009; 20:2380-2388.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2380-2388
    • Yang, H.C.1    Deleuze, S.2    Zuo, Y.3
  • 125
    • 50849105720 scopus 로고    scopus 로고
    • PPAR-gamma and aging: One link through klotho?
    • Zhang R, Zheng F. PPAR-gamma and aging: one link through klotho? Kidney Int 2008; 74:702-704.
    • (2008) Kidney Int , vol.74 , pp. 702-704
    • Zhang, R.1    Zheng, F.2
  • 126
    • 50849091263 scopus 로고    scopus 로고
    • Klotho is a target gene of PPAR-gamma
    • Zhang H, Li Y, Fan Y, et al. Klotho is a target gene of PPAR-gamma. Kidney Int 2008; 74:732-739.
    • (2008) Kidney Int , vol.74 , pp. 732-739
    • Zhang, H.1    Li, Y.2    Fan, Y.3
  • 127
    • 77956534990 scopus 로고    scopus 로고
    • Cell senescence in the aging kidney
    • Yang H, Fogo AB. Cell senescence in the aging kidney. J Am Soc Nephrol 2010; 21:1436-1439.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1436-1439
    • Yang, H.1    Fogo, A.B.2
  • 128
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356:2457-2471. (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2


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