A PPARγ agonist inhibits aldosterone-induced mesangial cell proliferation by blocking ROS-dependent EGFR intracellular signaling

American Journal of Physiology - Renal Physiology

Volumn 300, Issue 2, 2011, Pages

  Yuan, Yanggang ^a,b   Zhang, Aihua ^a,b   Huang, Songming ^a,b   Ding, Guixia ^a,b   Chen, Ronghua ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Medical University   (China)

Author keywords

Glomerular disease; Peroxisome proliferator activated receptor

Indexed keywords

ALDOSTERONE; CYCLIN A; CYCLIN D1; PD 68235; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; ROSIGLITAZONE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ALDOSTERONE ANTAGONIST; EPIDERMAL GROWTH FACTOR RECEPTOR; NITRO DERIVATIVE; PD 068235; THIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GLOMERULUS FILTRATION RATE; INHIBITION KINETICS; MESANGIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; PHOSPHORYLATION;

ALDOSTERONE; ALDOSTERONE ANTAGONISTS; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN A; CYCLIN D1; MESANGIAL CELLS; MICE; NITRO COMPOUNDS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; THIAZOLES; THIAZOLIDINEDIONES;

EID: 79551564896     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00418.2010     Document Type: Article

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