Transcriptional up-regulation of antioxidant genes by PPARδ inhibits angiotensin II-induced premature senescence in vascular smooth muscle cells

Biochemical and Biophysical Research Communications

Volumn 406, Issue 4, 2011, Pages 564-569

  Kim, Hyo Jung ^a   Ham, Sun Ah ^a   Paek, Kyung Shin ^b   Hwang, Jung Seok ^a   Jung, Si Young ^a   Kim, Min Young ^a   Jin, Hanna ^a   Kang, Eun Sil ^a   Woo, Im Sun ^a   Kim, Hye Jung ^a   Lee, Jae Heun ^a   Chang, Ki Churl ^a   Han, Chang Woo ^c   Seo, Han Geuk ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Semyung University   (South Korea)

^c Pusan National University   (South Korea)

Author keywords

Angiotensin II; Antioxidant genes; PPAR ; ROS; Senescence

Indexed keywords

[2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; ANGIOTENSIN II; GLUTATHIONE PEROXIDASE 1; HEME OXYGENASE 1; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; THIOREDOXIN 1;

ARTICLE; DNA DAMAGE; DOWN REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SENESCENCE; SMOOTH MUSCLE FIBER; TRANSCRIPTION REGULATION; UPREGULATION; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; CELL AGING; DNA DAMAGE; GENE EXPRESSION REGULATION; GLUTATHIONE PEROXIDASE; HEME OXYGENASE-1; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PPAR DELTA; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; THIAZOLES; THIOREDOXINS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 79953027322     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.091     Document Type: Article

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