메뉴 건너뛰기




Volumn 10, Issue 12, 2011, Pages

Quantitative chemical proteomics reveals new potential drug targets in head and neck cancer

Author keywords

[No Author keywords available]

Indexed keywords

5 (2,6 DICHLOROBENZYLSULFONYL) 3 [3,5 DIMETHYL 4 [2 (1 PYRROLIDINYLMETHYL) 1 PYRROLIDINYLCARBONYL] 1H PYRROL 2 YLMETHYLENE] 1,3 DIHYDRO 2H INDOL 2 ONE; CYCLIN DEPENDENT KINASE 1; DASATINIB; EPHRIN RECEPTOR A1; EPHRIN RECEPTOR A2; EPHRIN RECEPTOR A4; EPHRIN RECEPTOR B3; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GEFITINIB; JANUS KINASE 1; LAPATINIB; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEK9 PROTEIN; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE LYN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WEE1 PROTEIN;

EID: 83055168499     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M111.011635     Document Type: Article
Times cited : (64)

References (78)
  • 6
    • 0035872475 scopus 로고    scopus 로고
    • A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains
    • Redon, R., Muller, D., Caulee, K., Wanherdrick, K., Abecassis, J., and du Manoir, S. (2001) A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains. Cancer Res. 61, 4122-4129 (Pubitemid 32720980)
    • (2001) Cancer Research , vol.61 , Issue.10 , pp. 4122-4129
    • Redon, R.1    Muller, D.2    Caulee, K.3    Wanherdrick, K.4    Abecassis, J.5    Du, M.S.6
  • 10
    • 5044239253 scopus 로고    scopus 로고
    • Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage
    • DOI 10.1002/path.1630
    • Hague, A., Eveson, J. W., MacFarlane, M., Huntley, S., Janghra, N., and Thavaraj, S. (2004) Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage. J. Pathol. 204, 175-182 (Pubitemid 39335291)
    • (2004) Journal of Pathology , vol.204 , Issue.2 , pp. 175-182
    • Hague, A.1    Eveson, J.W.2    MacFarlane, M.3    Huntley, S.4    Janghra, N.5    Thavaraj, S.6
  • 11
    • 0031410093 scopus 로고    scopus 로고
    • Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck
    • DOI 10.1093/carcin/18.11.2285
    • Wang, D., Song, H., Evans, J. A., Lang, J. C., Schuller, D. E., and Weghorst, C. M. (1997) Mutation and downregulation of the transforming growth factor beta type II receptor gene in primary squamous cell carcinomas of the head and neck. Carcinogenesis 18, 2285-2290 (Pubitemid 28134761)
    • (1997) Carcinogenesis , vol.18 , Issue.11 , pp. 2285-2290
    • Wang, D.1    Song, H.2    Evans, J.A.3    Lang, J.C.4    Schuller, D.E.5    Weghorst, C.M.6
  • 12
    • 78650227959 scopus 로고    scopus 로고
    • EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: Attractive targets for molecular-oriented therapy
    • Freudlsperger, C., Burnett, J. R., Friedman, J. A., Kannabiran, V. R., Chen, Z., and Van Waes, C. (2011) EGFR-PI3K-AKT-mTOR signaling in head and neck squamous cell carcinomas: Attractive targets for molecular-oriented therapy. Expert Opin. Ther. Targets 15, 63-74
    • (2011) Expert Opin. Ther. Targets , vol.15 , pp. 63-74
    • Freudlsperger, C.1    Burnett, J.R.2    Friedman, J.A.3    Kannabiran, V.R.4    Chen, Z.5    Van Waes, C.6
  • 13
    • 78649469283 scopus 로고    scopus 로고
    • Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck
    • Sharafinski, M. E., Ferris, R. L., Ferrone, S., and Grandis, J. R. (2010) Epidermal growth factor receptor targeted therapy of squamous cell carcinoma of the head and neck. Head Neck 32, 1412-1421
    • (2010) Head Neck , vol.32 , pp. 1412-1421
    • Sharafinski, M.E.1    Ferris, R.L.2    Ferrone, S.3    Grandis, J.R.4
  • 14
    • 34147178690 scopus 로고    scopus 로고
    • The epidermal growth factor receptor (EGFR) in head and neck cancer: Its role and treatment implications
    • Zimmermann, M., Zouhair, A., Azria, D., and Ozsahin, M. (2006) The epidermal growth factor receptor (EGFR) in head and neck cancer: Its role and treatment implications. Radiat. Oncol. 1, 11
    • (2006) Radiat. Oncol. , vol.1 , pp. 11
    • Zimmermann, M.1    Zouhair, A.2    Azria, D.3    Ozsahin, M.4
  • 15
    • 40049099008 scopus 로고    scopus 로고
    • Clinical application of EGFR inhibitors in head and neck squamous cell cancer
    • Astsaturov, I., Cohen, R. B., and Harari, P. M. (2008) Clinical application of EGFR inhibitors in head and neck squamous cell cancer. Cancer Treat. Res. 139, 135-152
    • (2008) Cancer Treat. Res. , vol.139 , pp. 135-152
    • Astsaturov, I.1    Cohen, R.B.2    Harari, P.M.3
  • 16
    • 0034084314 scopus 로고    scopus 로고
    • Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis
    • Huang, S. M., and Harari, P. M. (2000) Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin. Cancer Res. 6, 2166-2174
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2166-2174
    • Huang, S.M.1    Harari, P.M.2
  • 17
    • 66349099167 scopus 로고    scopus 로고
    • Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma
    • Mazumdar, A., Henderson, Y. C., El-Naggar, A. K., Sen, S., and Clayman, G. L. (2009) Aurora kinase A inhibition and paclitaxel as targeted combination therapy for head and neck squamous cell carcinoma. Head Neck 31, 625-634
    • (2009) Head Neck , vol.31 , pp. 625-634
    • Mazumdar, A.1    Henderson, Y.C.2    El-Naggar, A.K.3    Sen, S.4    Clayman, G.L.5
  • 20
    • 34748916981 scopus 로고    scopus 로고
    • Quantitative mass spectrometry in proteomics: A critical review
    • DOI 10.1007/s00216-007-1486-6, Proteomics/Molecular Imaging
    • Bantscheff, M., Schirle, M., Sweetman, G., Rick, J., and Kuster, B. (2007) Quantitative mass spectrometry in proteomics: A critical review. Anal. Bioanal. Chem. 389, 1017-1031 (Pubitemid 47482251)
    • (2007) Analytical and Bioanalytical Chemistry , vol.389 , Issue.4 , pp. 1017-1031
    • Bantscheff, M.1    Schirle, M.2    Sweetman, G.3    Rick, J.4    Kuster, B.5
  • 21
    • 77954464041 scopus 로고    scopus 로고
    • Proteomics: A pragmatic perspective
    • Mallick, P., and Kuster, B. (2010) Proteomics: A pragmatic perspective. Nat. Biotechnol. 28, 695-709
    • (2010) Nat. Biotechnol. , vol.28 , pp. 695-709
    • Mallick, P.1    Kuster, B.2
  • 25
    • 78651340521 scopus 로고    scopus 로고
    • Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells
    • Kruse, U., Pallasch, C. P., Bantscheff, M., Eberhard, D., Frenzel, L., Ghidelli, S., Maier, S. K., Werner, T., Wendtner, C. M., and Drewes, G. (2011) Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells. Leukemia 25, 89-100
    • (2011) Leukemia , vol.25 , pp. 89-100
    • Kruse, U.1    Pallasch, C.P.2    Bantscheff, M.3    Eberhard, D.4    Frenzel, L.5    Ghidelli, S.6    Maier, S.K.7    Werner, T.8    Wendtner, C.M.9    Drewes, G.10
  • 26
    • 0028978505 scopus 로고
    • Cellular immortality: A late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss
    • Edington, K. G., Loughran, O. P., Berry, I. J., and Parkinson, E. K. (1995) Cellular immortality: A late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss. Mol. Carcinog. 13, 254-265
    • (1995) Mol. Carcinog. , vol.13 , pp. 254-265
    • Edington, K.G.1    Loughran, O.P.2    Berry, I.J.3    Parkinson, E.K.4
  • 27
    • 0036146820 scopus 로고    scopus 로고
    • Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection
    • Eicheler, W., Zips, D., Dörfler, A., Grénman, R., and Baumann, M. (2002) Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection. J. Histochem. Cytochem. 50, 197-204 (Pubitemid 34106758)
    • (2002) Journal of Histochemistry and Cytochemistry , vol.50 , Issue.2 , pp. 197-204
    • Eicheler, W.1    Zips, D.2    Dorfler, A.3    Grenman, R.4    Baumann, M.5
  • 29
    • 43049167326 scopus 로고    scopus 로고
    • High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx
    • DOI 10.1002/gcc.20551
    • Järvinen, A. K., Autio, R., Kilpinen, S., Saarela, M., Leivo, I., Grénman, R., Mäkitie, A. A., and Monni, O. (2008) High-resolution copy number and gene expression microarray analyses of head and neck squamous cell carcinoma cell lines of tongue and larynx. Genes Chromosomes Cancer 47, 500-509 (Pubitemid 351657185)
    • (2008) Genes Chromosomes and Cancer , vol.47 , Issue.6 , pp. 500-509
    • Jarvinen, A.-K.1    Autio, R.2    Kilpinen, S.3    Saarela, M.4    Leivo, I.5    Grenman, R.6    Makitie, A.A.7    Monni, O.8
  • 30
    • 0029116093 scopus 로고
    • Development of a new invasion and metastasis model of human oral squamous cell carcinomas
    • Kawashiri, S., Kumagai, S., Kojima, K., Harada, H., and Yamamoto, E. (1995) Development of a new invasion and metastasis model of human oral squamous cell carcinomas. Eur. J. Cancer B Oral. Oncol. 31B, 216-221
    • (1995) Eur. J. Cancer B Oral. Oncol. , vol.31 B , pp. 216-221
    • Kawashiri, S.1    Kumagai, S.2    Kojima, K.3    Harada, H.4    Yamamoto, E.5
  • 32
    • 33846546485 scopus 로고    scopus 로고
    • Head and neck squamous cell carcinoma cell lines: Established models and rationale for selection
    • DOI 10.1002/hed.20478
    • Lin, C. J., Grandis, J. R., Carey, T. E., Gollin, S. M., Whiteside, T. L., Koch, W. M., Ferris, R. L., and Lai, S. Y. (2007) Head and neck squamous cell carcinoma cell lines: Established models and rationale for selection. Head Neck 29, 163-188 (Pubitemid 46167784)
    • (2007) Head and Neck , vol.29 , Issue.2 , pp. 163-188
    • Lin, C.J.1    Grandis, J.R.2    Carey, T.E.3    Gollin, S.M.4    Whiteside, T.L.5    Koch, W.M.6    Ferris, R.L.7    Lai, S.Y.8
  • 33
    • 0024367423 scopus 로고
    • Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas
    • DOI 10.1111/j.1600-0714.1989.tb01570.x
    • Momose, F., Araida, T., Negishi, A., Ichijo, H., Shioda, S., and Sasaki, S. (1989) Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas. J. Oral Pathol. Med. 18, 391-395 (Pubitemid 20001923)
    • (1989) Journal of Oral Pathology and Medicine , vol.18 , Issue.7 , pp. 391-395
    • Momose, F.1    Araida, T.2    Negishi, A.3    Ichijo, H.4    Shioda, S.5    Sasaki, S.6
  • 34
    • 0034652487 scopus 로고    scopus 로고
    • Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells
    • O-charoenrat, P., Modjtahedi, H., Rhys-Evans, P., Court, W. J., Box, G. M., and Eccles, S. A. (2000) Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells. Cancer Res. 60, 1121-1128
    • (2000) Cancer Res. , vol.60 , pp. 1121-1128
    • O-charoenrat, P.1    Modjtahedi, H.2    Rhys-Evans, P.3    Court, W.J.4    Box, G.M.5    Eccles, S.A.6
  • 35
    • 0028363256 scopus 로고
    • Relation of DNA ploidy and proliferation rate to radiation sensitivity in squamous carcinoma cell lines
    • Pekkola-Heino, K., Joensuu, H., Klemi, P., and Grenman, R. (1994) Relation of DNA ploidy and proliferation rate to radiation sensitivity in squamous carcinoma cell lines. Arch. Otolaryngol. Head Neck Surg. 120, 750-754 (Pubitemid 24217589)
    • (1994) Archives of Otolaryngology - Head and Neck Surgery , vol.120 , Issue.7 , pp. 750-754
    • Pekkola-Heino, K.1    Joensuu, H.2    Klemi, P.3    Grenman, R.4
  • 36
    • 0026090857 scopus 로고
    • Effects of radiation fractionation on four squamous cell carcinoma lines with dissimilar inherent radiation sensitivity
    • Pekkola-Heino, K., Kulmala, J., Klemi, P., Lakkala, T., Aitasalo, K., Joensuu, H., and Grenman, R. (1991) Effects of radiation fractionation on four squamous cell carcinoma lines with dissimilar inherent radiation sensitivity. J. Cancer Res. Clin. Oncol. 117, 597-602
    • (1991) J. Cancer Res. Clin. Oncol. , vol.117 , pp. 597-602
    • Pekkola-Heino, K.1    Kulmala, J.2    Klemi, P.3    Lakkala, T.4    Aitasalo, K.5    Joensuu, H.6    Grenman, R.7
  • 38
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
    • Rheinwald, J. G., and Beckett, M. A. (1981) Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res. 41, 1657-1663 (Pubitemid 11114553)
    • (1981) Cancer Research , vol.41 , Issue.5 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 39
    • 34447302548 scopus 로고    scopus 로고
    • The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines
    • DOI 10.1016/j.oraloncology.2006.09.001, PII S1368837506002478
    • White, J. S., Weissfeld, J. L., Ragin, C. C., Rossie, K. M., Martin, C. L., Shuster, M., Ishwad, C. S., Law, J. C., Myers, E. N., Johnson, J. T., and Gollin, S. M. (2007) The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines. Oral Oncol. 43, 701-712 (Pubitemid 47058372)
    • (2007) Oral Oncology , vol.43 , Issue.7 , pp. 701-712
    • White, J.S.1    Weissfeld, J.L.2    Ragin, C.C.R.3    Rossie, K.M.4    Martin, C.L.5    Shuster, M.6    Ishwad, C.S.7    Law, J.C.8    Myers, E.N.9    Johnson, J.T.10    Gollin, S.M.11
  • 40
    • 0027132831 scopus 로고
    • A variant form of laminin is responsible for the neurite outgrowth-promoting activity in conditioned medium from a squamous carcinoma cell line
    • Yoshida, H., Hasegawa, S., Kuromi, H., Inagaki, N., Seino, S., Takahashi, K., and Sato, K. (1993) A variant form of laminin is responsible for the neurite outgrowth-promoting activity in conditioned medium from a squamous carcinoma cell line. Connect. Tissue Res. 30, 23-35 (Pubitemid 2019911)
    • (1993) Connective Tissue Research , vol.30 , Issue.1 , pp. 23-35
    • Yoshida, H.1    Hasegawa, S.2    Kuromi, H.3    Inagaki, N.4    Seino, S.5    Takahashi, K.6    Sato, K.7
  • 41
    • 69949157387 scopus 로고    scopus 로고
    • Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro
    • Zhang, N., Erjala, K., Kulmala, J., Qiu, X., Sundvall, M., Elenius, K., and Grénman, R. (2009) Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro. Radiother. Oncol. 92, 388-392
    • (2009) Radiother. Oncol. , vol.92 , pp. 388-392
    • Zhang, N.1    Erjala, K.2    Kulmala, J.3    Qiu, X.4    Sundvall, M.5    Elenius, K.6    Grénman, R.7
  • 43
  • 44
    • 11244346557 scopus 로고    scopus 로고
    • Variance stabilization applied to microarray data calibration and to the quantification of differential expression
    • Huber, W., von Heydebreck, A., Sultmann, H., Poustka, A., and Vingron, M. (2002) Variance stabilization applied to microarray data calibration and to the quantification of differential expression. Bioinformatics 1, (Suppl. 18) S96-S104 (Pubitemid 41185642)
    • (2002) Bioinformatics , vol.18 , Issue.SUPPL. 1
    • Huber, W.1    Von Heydebreck, A.2    Sultmann, H.3    Poustka, A.4    Vingron, M.5
  • 46
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3
    • Smyth, G. K. (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol. 3, Article3
    • (2004) Stat. Appl. Genet. Mol. Biol. , vol.3
    • Smyth, G.K.1
  • 48
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful approach to multiple testing
    • Benjamini, Y., and Hochberg, Y. (1995) Controlling the false discovery rate: A practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B Methodol. 57, 289-300
    • (1995) J. R. Stat. Soc. Ser. B Methodol. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 49
    • 78049363064 scopus 로고    scopus 로고
    • High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma
    • Rauser, S., Langer, R., Tschernitz, S., Gais, P., Jütting, U., Feith, M., Höfler, H., and Walch, A. (2010) High number of CD45RO+ tumor infiltrating lymphocytes is an independent prognostic factor in non-metastasized (stage I-IIA) esophageal adenocarcinoma. BMC Cancer 10, 608
    • (2010) BMC Cancer , vol.10 , pp. 608
    • Rauser, S.1    Langer, R.2    Tschernitz, S.3    Gais, P.4    Jütting, U.5    Feith, M.6    Höfler, H.7    Walch, A.8
  • 51
    • 37549047649 scopus 로고    scopus 로고
    • A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells
    • Wykosky, J., Gibo, D. M., and Debinski, W. (2007) A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells. Mol. Cancer Ther. 6, 3208-3218
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3208-3218
    • Wykosky, J.1    Gibo, D.M.2    Debinski, W.3
  • 52
    • 0037206953 scopus 로고    scopus 로고
    • Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade
    • DOI 10.1038/sj.onc.1205758
    • Pratt, R. L., and Kinch, M. S. (2002) Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade. Oncogene 21, 7690-7699 (Pubitemid 35398815)
    • (2002) Oncogene , vol.21 , Issue.50 , pp. 7690-7699
    • Pratt, R.L.1    Kinch, M.S.2
  • 54
    • 10644235453 scopus 로고    scopus 로고
    • Targeting protein kinases in cancer therapy: A success?
    • Pearson, M. A., and Fabbro, D. (2004) Targeting protein kinases in cancer therapy: A success? Expert Rev. Anticancer Ther. 4, 1113-1124 (Pubitemid 39646565)
    • (2004) Expert Review of Anticancer Therapy , vol.4 , Issue.6 , pp. 1113-1124
    • Pearson, M.A.1    Fabbro, D.2
  • 55
    • 33847622161 scopus 로고    scopus 로고
    • Targeting receptor tyrosine kinases and their signal transduction routes in head and neck cancer
    • DOI 10.1093/annonc/mdl175
    • Cruz, J. J., Ocaña, A., Del Barco, E., and Pandiella, A. (2007) Targeting receptor tyrosine kinases and their signal transduction routes in head and neck cancer. Ann. Oncol. 18, 421-430 (Pubitemid 46359619)
    • (2007) Annals of Oncology , vol.18 , Issue.3 , pp. 421-430
    • Cruz, J.J.1    Ocana, A.2    Del, B.E.3    Pandiella, A.4
  • 56
    • 73949087586 scopus 로고    scopus 로고
    • Personalized cancer therapy with selective kinase inhibitors: An emerging paradigm in medical oncology
    • McDermott, U., and Settleman, J. (2009) Personalized cancer therapy with selective kinase inhibitors: An emerging paradigm in medical oncology. J. Clin. Oncol. 27, 5650-5659
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5650-5659
    • McDermott, U.1    Settleman, J.2
  • 57
    • 25644454404 scopus 로고    scopus 로고
    • Pharmaceuticals: A new grammar for drug discovery
    • DOI 10.1038/437491a, PII 437491
    • Fishman, M. C., and Porter, J. A. (2005) Pharmaceuticals: A new grammar for drug discovery. Nature 437, 491-493 (Pubitemid 41613538)
    • (2005) Nature , vol.437 , Issue.7058 , pp. 491-493
    • Fishman, M.C.1    Porter, J.A.2
  • 59
    • 0037025173 scopus 로고    scopus 로고
    • Cancer: Addiction to oncogenes: The Achilles heal of cancer
    • Weinstein, I. B. (2002) Cancer: Addiction to oncogenes: The Achilles heal of cancer. Science 297, 63-64
    • (2002) Science , vol.297 , pp. 63-64
    • Weinstein, I.B.1
  • 60
    • 0033231927 scopus 로고    scopus 로고
    • The Aurora/Ipl1p kinase family: Regulators of chromosome segregation and cytokinesis
    • DOI 10.1016/S0962-8924(99)01658-X, PII S096289249901658X
    • Bischoff, J. R., and Plowman, G. D. (1999) The Aurora/Ipl1p kinase family: Regulators of chromosome segregation and cytokinesis. Trends Cell Biol. 9, 454-459 (Pubitemid 29469430)
    • (1999) Trends in Cell Biology , vol.9 , Issue.11 , pp. 454-459
    • Bischoff, J.R.1    Plowman, G.D.2
  • 61
    • 0032524908 scopus 로고    scopus 로고
    • RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
    • DOI 10.1074/jbc.273.20.12296
    • Inohara, N., del Peso, L., Koseki, T., Chen, S., and Núñez, G. (1998) RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. J. Biol. Chem. 273, 12296-12300 (Pubitemid 28240597)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.20 , pp. 12296-12300
    • Inohara, N.1    Del, P.L.2    Koseki, T.3    Chen, S.4    Nunez, G.5
  • 62
    • 27644466229 scopus 로고    scopus 로고
    • EphA2 as a novel molecular marker and target in glioblastoma multiforme
    • DOI 10.1158/1541-7786.MCR-05-0056
    • Wykosky, J., Gibo, D. M., Stanton, C., and Debinski, W. (2005) EphA2 as a novel molecular marker and target in glioblastoma multiforme. Mol. Cancer Res. 3, 541-551 (Pubitemid 41567273)
    • (2005) Molecular Cancer Research , vol.3 , Issue.10 , pp. 541-551
    • Wykosky, J.1    Gibo, D.M.2    Stanton, C.3    Debinski, W.4
  • 63
    • 28844447276 scopus 로고    scopus 로고
    • EphA2 as a target for ovarian cancer therapy
    • DOI 10.1517/14728222.9.6.1179
    • Landen, C. N., Kinch, M. S., and Sood, A. K. (2005) EphA2 as a target for ovarian cancer therapy. Expert Opin. Ther. Targets 9, 1179-1187 (Pubitemid 41762872)
    • (2005) Expert Opinion on Therapeutic Targets , vol.9 , Issue.6 , pp. 1179-1187
    • Landen, C.N.1    Kinch, M.S.2    Sood, A.K.3
  • 64
    • 1442308345 scopus 로고    scopus 로고
    • EphA2: A determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma
    • DOI 10.1038/sj.onc.1207247
    • Duxbury, M. S., Ito, H., Zinner, M. J., Ashley, S. W., and Whang, E. E. (2004) EphA2: A determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene 23, 1448-1456 (Pubitemid 38406840)
    • (2004) Oncogene , vol.23 , Issue.7 , pp. 1448-1456
    • Duxbury, M.S.1    Ito, H.2    Zinner, M.J.3    Ashley, S.W.4    Whang, E.E.5
  • 65
    • 67650403368 scopus 로고    scopus 로고
    • Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer
    • Brannan, J. M., Dong, W., Prudkin, L., Behrens, C., Lotan, R., Bekele, B. N., Wistuba, I., and Johnson, F. M. (2009) Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer. Clin. Cancer Res. 15, 4423-4430
    • (2009) Clin. Cancer Res. , vol.15 , pp. 4423-4430
    • Brannan, J.M.1    Dong, W.2    Prudkin, L.3    Behrens, C.4    Lotan, R.5    Bekele, B.N.6    Wistuba, I.7    Johnson, F.M.8
  • 67
    • 56249088261 scopus 로고    scopus 로고
    • Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: Correlation with the angiogenesis and clinical outcome
    • Shao, Z., Zhang, W. F., Chen, X. M., and Shang, Z. J. (2008) Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: Correlation with the angiogenesis and clinical outcome. Oral Oncol. 44, 1110-1117
    • (2008) Oral Oncol. , vol.44 , pp. 1110-1117
    • Shao, Z.1    Zhang, W.F.2    Chen, X.M.3    Shang, Z.J.4
  • 68
    • 57749121465 scopus 로고    scopus 로고
    • The EphA2 receptor and ephrinA1 ligand in solid tumors: Function and therapeutic targeting
    • Wykosky, J., and Debinski, W. (2008) The EphA2 receptor and ephrinA1 ligand in solid tumors: Function and therapeutic targeting. Mol. Cancer Res. 6, 1795-1806
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1795-1806
    • Wykosky, J.1    Debinski, W.2
  • 70
    • 68749084623 scopus 로고    scopus 로고
    • CYT387, a selective JAK1/JAK2 inhibitor: In vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients
    • Pardanani, A., Lasho, T., Smith, G., Burns, C. J., Fantino, E., and Tefferi, A. (2009) CYT387, a selective JAK1/JAK2 inhibitor: In vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients. Leukemia 23, 1441-1445
    • (2009) Leukemia , vol.23 , pp. 1441-1445
    • Pardanani, A.1    Lasho, T.2    Smith, G.3    Burns, C.J.4    Fantino, E.5    Tefferi, A.6
  • 71
    • 0842347483 scopus 로고    scopus 로고
    • Lyn Is a Target Gene for Prostate Cancer: Sequence-Based Inhibition Induces Regression of Human Tumor Xenografts
    • DOI 10.1158/0008-5472.CAN-03-2420
    • Goldenberg-Furmanov, M., Stein, I., Pikarsky, E., Rubin, H., Kasem, S., Wygoda, M., Weinstein, I., Reuveni, H., and Ben-Sasson, S. A. (2004) Lyn is a target gene for prostate cancer: Sequence-based inhibition induces regression of human tumor xenografts. Cancer Res. 64, 1058-1066 (Pubitemid 38176910)
    • (2004) Cancer Research , vol.64 , Issue.3 , pp. 1058-1066
    • Goldenberg-Furmanov, M.1    Stein, I.2    Pikarsky, E.3    Rubin, H.4    Kasem, S.5    Wygoda, M.6    Weinstein, I.7    Reuveni, H.8    Ben-Sasson, S.A.9
  • 72
    • 0030308959 scopus 로고    scopus 로고
    • Tyrosine kinases wee1 and mik1 as effectors of DNA replication checkpoint control
    • Tourret, J., and McKeon, F. (1996) Tyrosine kinases wee1 and mik1 as effectors of DNA replication checkpoint control. Prog. Cell Cycle Res. 2, 91-97
    • (1996) Prog. Cell Cycle Res. , vol.2 , pp. 91-97
    • Tourret, J.1    McKeon, F.2
  • 74
    • 77956819801 scopus 로고    scopus 로고
    • Adaptive radiation therapy for head and neck cancer-can an old goal evolve into a new standard?
    • Schwartz, D. L., and Dong, L. (2011) Adaptive radiation therapy for head and neck cancer-can an old goal evolve into a new standard? J. Oncol. 2011
    • (2011) J. Oncol. , vol.2011
    • Schwartz, D.L.1    Dong, L.2
  • 75
    • 70349758510 scopus 로고    scopus 로고
    • Src kinases as therapeutic targets for cancer
    • Kim, L. C., Song, L., and Haura, E. B. (2009) Src kinases as therapeutic targets for cancer. Nat. Rev. Clin. Oncol. 6, 587-595
    • (2009) Nat. Rev. Clin. Oncol. , vol.6 , pp. 587-595
    • Kim, L.C.1    Song, L.2    Haura, E.B.3
  • 76
    • 33745243692 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
    • DOI 10.1158/0008-5472.CAN-05-4620
    • Song, L., Morris, M., Bagui, T., Lee, F. Y., Jove, R., and Haura, E. B. (2006) Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res. 66, 5542-5548 (Pubitemid 43927102)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5542-5548
    • Song, L.1    Morris, M.2    Bagui, T.3    Lee, F.Y.4    Jove, R.5    Haura, E.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.