Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways

International Journal of Cancer

Volumn 128, Issue 7, 2011, Pages 1596-1605

  Smeets, Serge J ^a   Van Der Plas, Marlon ^a   Schaaij Visser, Tieneke B M ^a,b   Van Veen, Eva A M ^a   Van Meerloo, Johan ^a   Braakhuis, Boudewijn J M ^a   Steenbergen, Renske D M ^a   Brakenhoff, Ruud H ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

head and neck cancer; human papillomavirus; immortalization; p53; pRb

Indexed keywords

CYCLIN D1; MUTANT PROTEIN; PROTEIN E6; PROTEIN E7; PROTEIN P16; PROTEIN P53; RETINOBLASTOMA PROTEIN; SHORT HAIRPIN RNA; TELOMERASE; VIRUS LARGE T ANTIGEN; WNT PROTEIN;

ARTICLE; CARCINOGENESIS; CELL IMMORTALIZATION; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVITY; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HYPOXIA; KERATINOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA;

CALCIUM; CELL LINE, TUMOR; CYCLIN D1; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC VECTORS; HEAD AND NECK NEOPLASMS; HUMANS; KERATINOCYTES; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; PHENOTYPE; REPRESSOR PROTEINS; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79551504308     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25474     Document Type: Article

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