Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers

British Journal of Pharmacology

Volumn 165, Issue 1, 2012, Pages 208-222

  Aslam, M ^a   Pfeil, U ^a   Gunduz D ^b   Rafiq, A ^a   Kummer, W ^a   Piper, H M ^a   Noll, T ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

CGRP 8 37; intermedin; Rac1; RAMP2; thrombin

Indexed keywords

ACTIN; ADRENOMEDULLIN; ALBUMIN; ALPHA CALCITONIN GENE RELATED PEPTIDE[8-37]; CALCITONIN GENE RELATED PEPTIDE[8-37]; CALCITONIN RECEPTOR LIKE RECEPTOR; CELL PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INTERMEDIN; PROTEIN EPAC; RECEPTOR ACTIVITY MODIFYING PROTEIN 1; RECEPTOR ACTIVITY MODIFYING PROTEIN 2; RECEPTOR ACTIVITY MODIFYING PROTEIN 3; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBIN; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN;

ARTICLE; CELL ADHESION; CELL MEMBRANE PERMEABILITY; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; ENDOTHELIAL BARRIER; ENDOTHELIUM; ENZYME ACTIVATION; HORMONE ACTION; HUMAN; HUMAN CELL; MEMBRANE STABILIZATION; MONOLAYER CULTURE; MUSCLE FIBER CONTRACTION; NUCLEOTIDE SEQUENCE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRESS FIBER; UMBILICAL VEIN ENDOTHELIAL CELL;

ADHERENS JUNCTIONS; CALCITONIN GENE-RELATED PEPTIDE; CYCLIC AMP; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; HUMANS; MYOSIN LIGHT CHAINS; PEPTIDE HORMONES; RAC1 GTP-BINDING PROTEIN; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ADRENOMEDULLIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHOA GTP-BINDING PROTEIN; RNA; SIGNAL TRANSDUCTION; THROMBIN;

EID: 82955189754     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01540.x     Document Type: Article

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