메뉴 건너뛰기




Volumn 35, Issue 3, 2008, Pages 355-361

Adrenomedullin-2/intermedin induces cAMP accumulation in dissociated rat spinal cord cells: Evidence for the existence of a distinct class of sites of action

Author keywords

Adrenomedullin 2 intermedin; cAMP; CGRP; Rat adrenomedullin; Rat spinal cord

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN 2; AMYLIN DERIVATIVE; CYCLIC AMP; INTERMEDIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 51649120066     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-008-9062-x     Document Type: Article
Times cited : (17)

References (19)
  • 1
    • 0025195028 scopus 로고
    • HCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery
    • T. Dennis A. Fournier A. Cadieux 1990 hCGRP8-37, a calcitonin gene-related peptide antagonist revealing calcitonin gene-related peptide receptor heterogeneity in brain and periphery Journal of Pharmacology and Experimental Therapeutics 254 123 128
    • (1990) Journal of Pharmacology and Experimental Therapeutics , vol.254 , pp. 123-128
    • Dennis, T.1    Fournier, A.2    Cadieux, A.3
  • 2
    • 0033970471 scopus 로고    scopus 로고
    • Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
    • H. Doods G. Hallermayer D. Wu 2000 Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist British Journal of Pharmacology 129 420 423
    • (2000) British Journal of Pharmacology , vol.129 , pp. 420-423
    • Doods, H.1    Hallermayer, G.2    Wu, D.3
  • 3
    • 0021908752 scopus 로고
    • Interaction of calcitonin and calcitonin gene-related peptide at receptor sites in target tissues
    • D. Goltzman J. Mitchell 1985 Interaction of calcitonin and calcitonin gene-related peptide at receptor sites in target tissues Science 227 1343 1345
    • (1985) Science , vol.227 , pp. 1343-1345
    • Goltzman, D.1    Mitchell, J.2
  • 4
    • 34247466606 scopus 로고    scopus 로고
    • Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats
    • H. Hashimoto S. Hyodo M. Kawasaki 2007 Adrenomedullin 2 (AM2)/intermedin is a more potent activator of hypothalamic oxytocin-secreting neurons than AM possibly through an unidentified receptor in rats Peptides 28 1104 1112
    • (2007) Peptides , vol.28 , pp. 1104-1112
    • Hashimoto, H.1    Hyodo, S.2    Kawasaki, M.3
  • 5
    • 17844365264 scopus 로고    scopus 로고
    • Pharmacological discrimination of calcitonin receptor: Receptor activity-modifying protein complexes
    • D. L. Hay G. Christopoulos A. Christopoulos D. R. Poyner P. M. Sexton 2005 Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes Molecular Pharmacology 67 1655 1665
    • (2005) Molecular Pharmacology , vol.67 , pp. 1655-1665
    • Hay, D.L.1    Christopoulos, G.2    Christopoulos, A.3    Poyner, D.R.4    Sexton, P.M.5
  • 7
    • 0142153874 scopus 로고    scopus 로고
    • CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: A comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS
    • D. L. Hay S. G. Howitt A. C. Conner M. Schindler D. M. Smith D. R. Poyner 2003 CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS British Journal of Pharmacology 140 477 486
    • (2003) British Journal of Pharmacology , vol.140 , pp. 477-486
    • Hay, D.L.1    Howitt, S.G.2    Conner, A.C.3    Schindler, M.4    Smith, D.M.5    Poyner, D.R.6
  • 8
    • 0025944383 scopus 로고
    • Comparative affinities and antagonistic potencies of various human calcitonin gene-related peptide fragments on calcitonin gene-related peptide receptors in brain and periphery
    • M. Mimeault A. Fournier Y. Dumont S. St-Pierre R. Quirion 1991 Comparative affinities and antagonistic potencies of various human calcitonin gene-related peptide fragments on calcitonin gene-related peptide receptors in brain and periphery Journal of Pharmacology and Experimental Therapeutics 258 1084 1090
    • (1991) Journal of Pharmacology and Experimental Therapeutics , vol.258 , pp. 1084-1090
    • Mimeault, M.1    Fournier, A.2    Dumont, Y.3    St-Pierre, S.4    Quirion, R.5
  • 9
    • 34247521933 scopus 로고    scopus 로고
    • Expression of adrenomedullin2/intermedin in human brain, heart, and kidney
    • R. Morimoto F. Satoh O. Murakami 2007 Expression of adrenomedullin2/ intermedin in human brain, heart, and kidney Peptides 28 1095 1103
    • (2007) Peptides , vol.28 , pp. 1095-1103
    • Morimoto, R.1    Satoh, F.2    Murakami, O.3
  • 10
    • 0029840953 scopus 로고    scopus 로고
    • Characterisation and molecular identification of adrenomedullin binding sites in the rat spinal cord: A comparison with calcitonin gene-related peptide receptors
    • A. A. Owji J. V. Gardiner P. D. Upton 1996 Characterisation and molecular identification of adrenomedullin binding sites in the rat spinal cord: a comparison with calcitonin gene-related peptide receptors Journal of Neurochemistry 67 2172 2179
    • (1996) Journal of Neurochemistry , vol.67 , pp. 2172-2179
    • Owji, A.A.1    Gardiner, J.V.2    Upton, P.D.3
  • 11
    • 0026502217 scopus 로고
    • Pharmacological characterization of a receptor for calcitonin gene-related peptide on rat, L6 myocytes
    • D. R. Poyner D. P. Andrew D. Brown C. Bose M. R. Hanley 1992 Pharmacological characterization of a receptor for calcitonin gene-related peptide on rat, L6 myocytes British Journal of Pharmacology 105 441 447
    • (1992) British Journal of Pharmacology , vol.105 , pp. 441-447
    • Poyner, D.R.1    Andrew, D.P.2    Brown, D.3    Bose, C.4    Hanley, M.R.5
  • 12
    • 0036266044 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXXII. the mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors
    • D. R. Poyner P. M. Sexton I. Marshall 2002 International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors Pharmacological Reviews 54 233 246
    • (2002) Pharmacological Reviews , vol.54 , pp. 233-246
    • Poyner, D.R.1    Sexton, P.M.2    Marshall, I.3
  • 13
    • 1342346545 scopus 로고    scopus 로고
    • Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes
    • J. Roh C. L. Chang A. Bhalla C. Klein S. Y. Hsu 2004 Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes Journal of Biological Chemistry 279 7264 7274
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 7264-7274
    • Roh, J.1    Chang, C.L.2    Bhalla, A.3    Klein, C.4    Hsu, S.Y.5
  • 15
    • 0346094400 scopus 로고    scopus 로고
    • Identification of novel adrenomedullin in mammals: A potent cardiovascular and renal regulator
    • Y. Takei K. Inoue M. Ogoshi T. Kawahara H. Bannai S. Miyano 2004 Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator FEBS Letters 556 53 58
    • (2004) FEBS Letters , vol.556 , pp. 53-58
    • Takei, Y.1    Inoue, K.2    Ogoshi, M.3    Kawahara, T.4    Bannai, H.5    Miyano, S.6
  • 16
    • 33745103433 scopus 로고    scopus 로고
    • Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene-related peptide (CGRP) receptors in dissociated rat spinal cord cell culture
    • M. A. Takhshid D. R. Poyner J. G. Chabot 2006 Characterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene-related peptide (CGRP) receptors in dissociated rat spinal cord cell culture British Journal of Pharmacology 148 459 468
    • (2006) British Journal of Pharmacology , vol.148 , pp. 459-468
    • Takhshid, M.A.1    Poyner, D.R.2    Chabot, J.G.3
  • 18
    • 30944435085 scopus 로고    scopus 로고
    • Intermedin/adrenomedullin-2 inhibits growth hormone release from cultured, primary anterior pituitary cells
    • M. M. Taylor S. L. Bagley W. K. Samson 2006 Intermedin/adrenomedullin-2 inhibits growth hormone release from cultured, primary anterior pituitary cells Endocrinology 147 859 864
    • (2006) Endocrinology , vol.147 , pp. 859-864
    • Taylor, M.M.1    Bagley, S.L.2    Samson, W.K.3
  • 19
    • 0030665019 scopus 로고    scopus 로고
    • Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors
    • D. van Rossum U. K. Hanisch R. Quirion 1997 Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors Neuroscience and Biobehavioral Reviews 21 649 678
    • (1997) Neuroscience and Biobehavioral Reviews , vol.21 , pp. 649-678
    • Van Rossum, D.1    Hanisch, U.K.2    Quirion, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.