Adrenomedullin-2, a novel calcitonin/calcitonin-gene-related peptide family peptide, relaxes rat mesenteric artery: Influence of pregnancy

Endocrinology

Volumn 148, Issue 4, 2007, Pages 1727-1735

  Chauhan, Madhu ^a   Ross, Gracious R ^a   Yallampalli, Uma ^a   Yallampalli, Chandra ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENOSINE 3',5' PHOSPHOROTHIOATE; ADRENOMEDULLIN; ADRENOMEDULLIN 2; CALCIUM ACTIVATED POTASSIUM CHANNEL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; GLIBENCLAMIDE; GUANYLATE CYCLASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; TETRYLAMMONIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG MECHANISM; ENDOTHELIUM; ENZYME INHIBITION; FEMALE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INCUBATION TIME; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; MYOGRAPHY; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; VASODILATATION; WESTERN BLOTTING;

ADRENOMEDULLIN; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; GUANYLATE CYCLASE; MESENTERIC ARTERIES; NEUROPEPTIDES; NITRIC OXIDE SYNTHASE; ORGAN CULTURE TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PREGNANCY; PREGNANCY, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; VASODILATION;

EID: 33947385791     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1105     Document Type: Article

References (35)

1. Ahmed B 2004 Study of peripheral circulation in non-pregnant, pregnant and pre-eclamptic women using applied potential tomography. Aust NZ J Obstet Gynaecol 44:322-327
2. Yong EM, Mano MT, Head RJ 1992 Neurovascular function during pregnancy in the spontaneously hypertensive rat. Clin Exp Pharmacol Physiol 19:415-423
3. Jerat S, Kaufman S 1998 Effect of pregnancy and steroid hormones on plasma adrenomedullin levels in the rat. Can J Physiol Pharmacol 76:463-466
4. Gangula PR, Wimalawansa SJ, Yallampalli C 2000 Pregnancy and sex steroid hormones enhance circulating calcitonin gene-related peptide levels in rats. Hum Reprod 15:949-953
5. Paller MS 1984 Mechanism of decreased pressor responsiveness to ANG II, NE, and vasopressin in pregnant rats. Am J Physiol 247:H100-H108
6. Yallampalli C, Dong YL, Wimalawansa SJ 1996 CGRP reverses the hypertension and significantly decreases the fetal mortality in preeclampsia rats induced by nitro-l-arginine methyl ester. Hum Reprod 11:895-899
7. Stevenson JC, MacDonald DWR, Warren RC, Booker MW, Whitehead MI 1986 Increased concentration of circulating calcitonin gene-related peptide during normal human pregnancy. Br Med J (Clin Res Ed) 293:1329-1330
8. Di Iorio R, Marinoni E, Letizia C, Villaccio B, Alberini A, Cosmi EV 1999 Adrenomedullin production is increased in normal human pregnancy. Eur J Endocrinol 140:201-206
9. Kobayashi KKT, Aso T, Hirata Y, Imai TM 2000 Immunoreactive adrenomedullin (AM) concentration in maternal plasma during human pregnancy and AM expression in placenta. Eur J Endocrinol 142:683-687
10. Makino Y, Shibata K, Makino I, Kangawa K, Kawarabayashi T 2001 Alteration of the adrenomedullin receptor components gene expression associated with the blood pressure in pregnancy-induced hypertension. J Clin Endocrinol Metab 86:5079-5082
11. Roh J, Chang CL, Bhalla A, Klein C, Hsu SY 2004 Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes. J Biol Chem 279:7264-7274
12. Chang CL, Roh J, Hsu SY 2004 Intermedin, a novel calcitonin family peptide that exists in teleosts as well as in mammals: a comparison with other calcitonin/ intermedin family peptides in vertebrates. Peptides 25:1633-1642
13. Poyner DR, Sexton PM, Marshall I, Smith DM, Quirion R, Born W, Muff R, Fischer JA, Foord SM 2002 International union of pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol Rev 54:233-246
14. Chauhan M, Thota CS, Kondapaka S, Wimalawansa SJ, Yallampalli C 2003 Evidence for the existence of a new receptor for CGRP, which is not CRLR. Peptides 24:65-71
15. Chauhan M, Rajarathnam K, Yallampalli C 2005 Role of the N-terminal domain of the calcitonin receptor-like receptor in ligand binding. Biochemistry 44:782-789
16. Yallampalli C, Chauhan M, Thota CS, Kondapaka SB, Wimalawansa SJ 2002 Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity. Trends Endocrinol Metab 13:263-269
17. Taylor MM, Bagley SL, Samson WK 2005 Intermedin/adrenomedullin-2 acts within the central nervous system to elevate blood pressure and inhibit food and water intake. Am J Physiol Regul Integr Comp Physiol 288:R919-R927
18. Burak Kandilci H, Gumusel B, Wasserman A, Witriol N, Lippton H 2006 Intermedin/adrenomedullin-2 dilates the rat pulmonary vascular bed: dependence on CGRP receptors and nitric oxide release. Peptides 27:1390-1396
19. Pan CS, Yang JH, Cai DY, Zhao J, Gerns H, Yang J, Chang JK, Tang CS, Qi YF 2005 Cardiovascular effects of newly discovered peptide intermedin/adrenomedullin 2. Peptides 26:1640-1646
20. Lin CC, Roh J, Park JI, Klein C, Cushman N, Haberberger RV, Hsu SY 2005 Intermedin functions as a pituitary paracrine factor regulating prolactin release. Mol Endocrinol 19:2824-2838
21. Yang JH, Qi YF, Jia YX, Pan CS, Zhao J, Yang J, Chang JK, Tang CS 2005 Protective effects of intermedin/adrenomedullin2 on ischemia/reperfusion injury in isolated rat hearts. Peptides 26:501-507
22. Dong YL, Gangula PRR, Yallampalli C 1996 Nitric oxide synthase isoforms in rat uterus: differential regulation during pregnancy and labor. J Reprod Fertil 107:249-254
23. Yang JH, Pan CS, Jia YX, Zhang J, Zhao J, Pang YZ, Yang J, Tang CS, Qi YF 2006 Intermedin1-53 activates l-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas. Biochem Biophys Res Commun 341:567-572
24. Gangula PR, Lanlua P, Bukoski RD, Wimalawansa SJ, Yallampalli C 2004 Mesenteric arterial relaxation to calcitonin gene-related peptide is increased during pregnancy and by sex steroid hormones. Biol Reprod 71:1739-1745
25. Ross GR, Chauhan M, Gangula PR, Reed L, Thota C, Yallampalli C 2005 Female sex steroids increase adrenomedullin-induced vasodilation by increasing the expression of adrenomedullin2 receptor components in rat mesenteric artery. Endocrinology 147:389-396
26. Yallampalli C, Kondapaka SB, Lanlua P, Wimalawansa SJ, Gangula PR 2004 Female sex steroid hormones and pregnancy regulate receptors for calcitonin gene-related peptide in rat mesenteric arteries, but not in aorta. Biol Reprod 70:1055-1062
27. Thota C, Gangula PRR, Dong YL, Yallampalli C 2003 Changes in the expression of CRLR, RAMP1, RAMP2 and RAMP3 in rat uterus during pregnancy, labor and by steroid hormone treatments. Biol Reprod 69:1432-1437
28. Ignarro LJ, Kadowitz PJ 1985 The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation. Annu Rev Pharmacol Toxicol 25:171-191
29. Conrad KP, Vernier KA 1989 Plasma level, urinary excretion, and metabolic production of cGMP during gestation in rats. Am J Physiol 257:R847-R853
30. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA 1994 Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368:850-853
31. +-pump inhibitors and membrane depolarizing agents on acetylcholine-induced endothelium-dependent relaxation and cyclic GMP accumulation in rat aorta. Eur J Pharmacol 110:203-209
32. Hobara N, Nakamura A, Ohtsuka A, Narasaki M, Shibata K, Gomoita Y, Kawasaki H 2004 Distribution of adrenomedullin-containing perivascular nerves in the rat mesenteric artery. Peptides 25:589-599
33. Kashihara Y, Sakaguchi M, Kuno M 1989 Axonal transport and distribution of endogenous calcitonin gene-related peptide in rat peripheral nerve. J Neurosci 9:3796-3802
34. Xu HL, Wolde HM, Gavrilyuk V, Baughman VL, Pelligrino DA 2004 cAMP modulates cGMP-mediated cerebral arteriolar relaxation in vivo. Am J Physiol Heart Circ Physiol 287:H2501-H2509
35. Lu LF, Fiscus RR 1999 Nitric oxide donors enhance calcitonin gene-related peptide-induced elevations of cyclic AMP in vascular smooth muscle cells. Eur J Pharmacol 376:307-314