Role of collagens and perlecan in microvascular stability: Exploring the mechanism of capillary vessel damage by snake venom metalloproteinases

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Escalante, Teresa ^a   Ortiz, Natalia ^a   Rucavado, Alexandra ^a   Sanchez, Eladio F ^b   Richardson, Michael ^b   Fox, Jay W ^c   Gutiérrez, José María ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

^b FUNDAÇÃO EZEQUIEL DIAS   (Brazil)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASEMENT MEMBRANE PROTEIN; COLLAGEN; COLLAGEN TYPE 15; COLLAGEN TYPE 4; COLLAGEN TYPE 6; ENTACTIN; LAMININ; LEUCUROLYSIN A; MATRIGEL; MEMBRANE PROTEIN; METALLOPROTEINASE; PERLECAN; PROTEIN BAP1; SNAKE VENOM; UNCLASSIFIED DRUG; ALPHA GLOBULIN; ALPHA(2) MICROGLOBULIN; ALPHA(2)-MICROGLOBULIN; AZOCASEIN; BAP1 METALLOPROTEINASE; CASEIN; INSULIN; PROTEOGLYCAN; PROTEOHEPARAN SULFATE; SCLEROPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BLOOD VESSEL INJURY; BLOOD VESSEL PARAMETERS; BOTHROPS ASPER; BOTHROPS LEUCURUS; CAPILLARY VESSEL INJURY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; EXTRACELLULAR MATRIX; EXUDATE; GASTROCNEMIUS MUSCLE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MICROVASCULAR STABILITY; MOUSE; MUSCLE BLEEDING; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN HYDROLYSIS; PROTEOMICS; SNAKE; SNAKEBITE; TANDEM MASS SPECTROMETRY; TISSUE HOMOGENATE; WESTERN BLOTTING; ANIMAL; BLEEDING; CAPILLARY; DRUG COMBINATION; DRUG EFFECT; ENZYMOLOGY; HYDROLYSIS; INJURY; METABOLISM; MOLECULAR WEIGHT; MUSCLE; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ALPHA-GLOBULINS; ANIMALS; BASEMENT MEMBRANE; BLOTTING, WESTERN; BOTHROPS; CAPILLARIES; CASEINS; COLLAGEN; CROTALID VENOMS; DRUG COMBINATIONS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR MATRIX PROTEINS; EXUDATES AND TRANSUDATES; HEMORRHAGE; HEPARAN SULFATE PROTEOGLYCANS; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; INSULIN; LAMININ; METALLOENDOPEPTIDASES; METALLOPROTEASES; MICE; MOLECULAR WEIGHT; MUSCLES; PROTEOGLYCANS; PROTEOLYSIS; PROTEOMICS; WOUNDS AND INJURIES;

EID: 82955187846     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028017     Document Type: Article

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