Purification, cloning and sequence analyses for pro-metalloprotease- disintegrin variants from Deinagkistrodon acutus venom and subclassification of the small venom metalloproteases

European Journal of Biochemistry

Volumn 267, Issue 5, 2000, Pages 1359-1367

  Tsai, Inn Ho ^a,d   Wang, Ying Ming ^a   Chiang, Tzen Yuh ^b   Chen, Yuh Ling ^a   Huang, Ruey Jen ^c  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c DEPARTMENT OF HEALTH   (Taiwan)

^d NONE   (Taiwan)

Author keywords

Disintegrin; Hemorrhagin; Metalloprotease; Phylogenetic analysis; Snake venom (Deinagkistrodon acutus)

Indexed keywords

DISINTEGRIN; METALLOPROTEINASE; SNAKE VENOM;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME STRUCTURE; MASS SPECTROMETRY; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

AGKISTRODON; AMINO ACID SEQUENCE; ANIMALS; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CLONING, MOLECULAR; DISINTEGRINS; DNA, COMPLEMENTARY; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE HOMOLOGY, AMINO ACID; VIPER VENOMS;

AMPHIBIA; DEINAGKISTRODON ACUTUS; REPTILIA; SERPENTES;

EID: 0034053413     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01129.x     Document Type: Article

References (40)

1. 1. Bjarnason, J.B. & Fox, J.B. (1995) Snake venoms metalloendopeptidases: reprolysins. Methods Enzymol. 248, 345-368.
2. 2. Takeya, H. & Iwanaga, S. (1998) Proteases that induce hemorrhage. In Enzyme from Snake Venom (Bailey, G.S., ed.), pp. 11-38. Alaken, Inc., Fort Collins, CO.
3. 3. Markland, F.S. (1998) Fibrinogenolytic and fibrinolytic enzymes. In Enzyme from Snake Venom (Bailey, G.S., ed.), pp. 71-149. Alaken, Inc., Fort Collins, CO.
4. 4. Fox, J.W. & Long, C. (1998) The ADAMs/MDC family of proteins and their relationships to the snake venom metalloproteinases. In Enzyme from Snake Venom (Bailey, G.S., ed.), pp. 151-178. Alaken, Inc., Fort Collins, CO.
5. 5. Hite, L.A., Jia, L.A., Bjarnason, J.B. & Fox, J.W. (1994) cDNA sequence for four snake venom metalloproteinases: structure, classification and their relationship to mammalian reproductive proteins. Arch. Biochem. Biophys. 308, 182-191.
6. 6. Bjarnason, J.B. & Fox, J.W. (1994) Hemorrhagic metalloproteinase from snake venoms. Pharmac. Ther. 62, 325-372.
7. 7. Zhou, Q., Dangelmaier, C. & Smith, J.B. (1996) The hemorrhagin catrocollastatin inhibits collagen-induced platelet aggregation by binding to collagen via its disintegrin-like domain. Biochem. Biophys. Res. Commun. 219, 720-726.
8. 8. Mori, N., Nikai, T. & Sugihara, H. (1984) Purification of a proteinase (Ac5-proteinase) and characterization of hemorrhagic toxins from the venom of the hundred-pace snake (Agkistrodon acutus). Toxicon 22, 451-461.
9. 9. Ouyang, C. & Huang, T.F. (1977) The properties of the purified fibrinolytic principle from Agkistrodon acutus snake venom. Toxicon 15, 161-167.
10. 10. Xu, X., Wang, C., Liu, J. & Lu, Z. (1981) Purification and characterization of hemorrhagic components from Agkistrodon acutus (hundred pace snake) venom. Toxicon 19, 633-644.
11. 11. Gong, W., Teng, M. & Niu, L. (1997) Crystal structure determination of alkaline hemorrhagin AaH-Go from the snake venom of Agkistrodon acutus. Sci. China (Series C) 40, 351-355.
12. 12. Gong, W., Zhu, Z., Liu, S., Teng, M. & Niu, L. (1998) Crystal structures of acutolysin A, a three-disulfide hemorrhagic zinc metalloproteinase from the snake venom of Agkistrodon acutus. J. Mol. Biol. 283, 657-668.
13. 13. Nikai, T., Kato, C., Komori, Y., Nodani, H., Homma, M. & Sugihara, H. (1995) Primary structure of Acl-protease from the venom of Deinagkistrodon acutus (hundred-pace snake) from Taiwan. Biol. Pharm. Bull. 18, 631-633.
14. 14. Du, X.Y., Pan, H., Jin, Y., Zhu, H., Wu, X.F. & Zhou, Y.C. (1997) Purification, cDNA cloning and molecular characteristic of a fibrinolytic enzyme from the venom of Agkistrodon acutus. J. Nat. Toxins 7, 159-172.
15. 15. Liu, Q., Xu, W., Cheng, W., Jin, G., Shen, X., Lou, H. & Liu, J. (1999) Molecular cloning and sequence analysis of cDNA encoding haemorrhagic toxin acutolysin A from Agkistrodon acutus. Toxicon 37, 1539-1548.
16. 16. Yeh, C.H., Peng, H.-C., Yih, J.B. & Huang, T.F. (1998) A new short chain RGD-containing disintegrin, accutin, inhibits the common pathway of human platelet aggregation. Biochim. Biophys. Acta 1425, 493-504.
17. 17. Tsai, I.H., Wang, Y.M., Huang, R.J. & Liau, M.Y. (1997) Cloning and the deduced primary structures of pro-metalloproteases from the venom of Deinagkistrodon acutus. Thromb. Haemost. 79, 2659-2691.
18. 18. Paine, M.J., Desmond, H.P., Theakston, R.D. & Crampton, J.M. (1992) Purification, cloning and molecular characterization of a high molecular weight hemorrhagic metalloproteinase, jararhagin, from Bothorps jararca venom. J. Biol. Chem. 267, 22869-22876.
19. 19. Maniatis, T., Fritsch, E.F. & Sambrook, J. (1982) Molecular Cloning: a Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
20. 20. Hite, L.A., Jia, L.G., Bjarnason, J.B. & Fox, J.B. (1994) cDNA sequences for four snake venom metalloproteinases: structure, classification and their relationship to mammalian reproductive proteins. Arch. Biochem. Biophys. 308, 182-191.
21. 21. Tsai, I.H., Wang, Y.M. & Lee, Y.H. (1994) Characterization of a cDNA encoding the precursor of platelet aggregation inhibitor and metalloproteinase from Trimeresurus mucrosquamatus venom. Biochim. Biophys. Acta 1200, 337-340.
22. 22. Neeper, M.P. & Jacobson, M.A. (1990) Sequence of a cDNA encoding the platelet aggregation inhibitor trigramin. Nucleic Acids Res. 18, 4255.
23. 23. Au, L.C., Chou, J.S., Chang, K.J., Teh, G.W. & Lin, S.B. (1993) Nucleotide sequence of a full-length cDNA encoding a common precursor of platelet aggregation inhibitor and hemorrhagic protein from Calloselasma rhodostoma venom. Biochim. Biophys. Acta 1173, 243-245.
24. 24. Swofford, D.L. (1993) PAUP: Phylogenetic Analysis Using Parsimony, Version 3.1.1. Computer program distributed by the Illinois Natural History Survey, Champaign, IL.
25. 25. Hillis, D.M. & Bull., J.J. (1993) An empirical test of bootstrapping as a method assessing confidence in phylogenetic analysis. Syst. Biol. 42, 182-192.
26. 26. Nishida, S., Fujita, T., Kohno, N., Atoda, H., Morita, T., Takeya, H., Kido, I., Paine, M.J.I., Kawabata, S. & Iwanaga, S. (1995) cDNA cloning and deduced amino acid sequense of prothrombin activator (Ecarin) from Kenyan Echis carinatus venom. Biochemistry 34, 1771-1778.
27. 2 from the venom of Deinagkistrodon acutus. Toxicon 34, 1191-1196.
28. 28. Trikha, M., Schmitmeier, S. & Markland, F.S. (1994) Purification and characterization of fibrolase isoforms from venom of individual southern copperhead (Agkistrodon contortrix contortrix) snakes. Toxicon 32, 1521-1531.
29. 29. Tan, H.-H., Ponnudurai, G. & Chung, M.C.M. (1997) Proteolytic specificity of rhodostoxin, the major hemorrhagin of Calloselasma rhodostoma (Malayan pit viper) venom. Toxicon 35, 979-984.
30. 30. Mori, N., Nikai, T., Sugihara, H. & Tu, A.T. (1987) Biochemical characterization of hemorrhagic toxins with fibrinogenase activity isolated from Crotalus ruber ruher venom. Arch. Biochem. Biophys. 253, 108-121.
31. 31. Rucavado, A., Flores-sanchez, E.F., Franceschi, A., Magalhaes, A. & Gutierrez, J.M. (1999) Characterization of the local tissue damage induced by LKF-II, a metalloproteinase with weak hemorrhagic activity isolated from Lachesis muta muta snake venom. Toxicon 37, 1297-1312.
32. 32. Mashiko, H. & Takahashi, H. (1998) Haemorrhagic factors from snake venoms. Ma. Structures of haemorrhagic factors and types and mechanisms of haemorrhage. J. Toxicol. Toxin Rev. 17, 493-510.
33. 33. Ouyang, C., Teng, C.M. & Huang, T.F. (1992) Characterization of snake venom components acting on blood coagulation and platelet function. Toxicon 30, 945-966.
34. 34. Zhang, D., Botos, I., Gomis-Rüth, F.X., Doll, R., Blood, C., Njoroge, F.G., Fox, J.W., Bode, W. & Meyer, E.F. (1994) Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Proc. Natl Acad. Sci. USA 91, 8447-8451.
35. 35. Kumasaka, T., Yamamoto, M., Moriyama, H., Tanaka, N., Sato, M., Katsube, Y., Yamakawa, Y, Omori-Satoh, T., Iwanaga, S. & Ueki, T. (1996) Crystal structure of H2-proteinase from the venom of Trimeresurus flavoviridis. J. Biochem. 119, 49-57.
36. 36. Gomis-Rüth, F.X., Kress, L.F. & Bode, W. (1993) First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/ collagenases. EMBO J. 12, 4151-4157.
37. 37. Kini, R.M. & Evan, H.J. (1995) A novel approach to the design of potent bioactive peptides by incorporation of proline brackets: antiplatelet effects of Arg-Gly-Asp peptides. FEBS Lett. 375, 15-17.
38. 38. Selistre-de-Araujo, H.S. & Ownby, C.L. (1995) Molecular cloning and sequence analysis of cDNA for metalloproteinase from broad-banded copperhead Agkistrodon contortrix laticinctus. Arch. Biochem. Biophys. 320, 41-148.
39. 39. Siigur, E., Aaspõllu, A., Tu, A.T. & Siigur, J. (1996) cDNA cloning and deduced amino acid sequence of fibrinolytic enzyme (lebetase) from Vipera lebetina snake venom. Biochem. Biophys. Res. Commun. 224, 229-236.
40. 40. Terada, S., Hori, J., Fujimura, S. & Kimoto, E. (1999) Purification and amino acid sequence of brevilysin L6, a non-hemorrhagic metalloprotease from Agkistrodon halys brevicaudus venom. J. Biochem. 125, 64-69.