메뉴 건너뛰기




Volumn 11, Issue 24, 2011, Pages 4595-4609

Peptide arrays for kinome analysis: New opportunities and remaining challenges

Author keywords

Kinase; Kinome; Peptide array; Phosphoproteome; Phosphorylation; Protein arrays

Indexed keywords

ADENOSINE TRIPHOSPHATE; KINOME; PHOSPHOPROTEOME; PHOSPHOTRANSFERASE; PROTEOME; UNCLASSIFIED DRUG;

EID: 82955187031     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.201100296     Document Type: Review
Times cited : (77)

References (58)
  • 1
    • 2042464495 scopus 로고
    • Phosphorylase activity of skeletal muscle extracts
    • Krebs, E. G., Fischer, E. H., Phosphorylase activity of skeletal muscle extracts. J. Biol. Chem. 1955, 216, 113-120.
    • (1955) J. Biol. Chem. , vol.216 , pp. 113-120
    • Krebs, E.G.1    Fischer, E.H.2
  • 2
    • 0000187410 scopus 로고
    • Conversion of phosphorylase b to phosphorylase a in muscle extracts
    • Fischer, E. H., Krebs, E. G., Conversion of phosphorylase b to phosphorylase a in muscle extracts. J. Biol. Chem. 1955, 216, 121-132.
    • (1955) J. Biol. Chem. , vol.216 , pp. 121-132
    • Fischer, E.H.1    Krebs, E.G.2
  • 4
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: the yin and yang of protein phsophorylation and signaling
    • Hunter, T., Protein kinases and phosphatases: the yin and yang of protein phsophorylation and signaling. Cell 1995, 80, 225-236.
    • (1995) Cell , vol.80 , pp. 225-236
    • Hunter, T.1
  • 6
    • 0031895154 scopus 로고    scopus 로고
    • DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies
    • Knuutila, S., Bjorkqvist, A. M., Autio, K., Tarkkaqnen, M. et al., DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. Am. J. Pathol. 1998, 152, 1107-1123.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1107-1123
    • Knuutila, S.1    Bjorkqvist, A.M.2    Autio, K.3    Tarkkaqnen, M.4
  • 7
    • 0036527429 scopus 로고    scopus 로고
    • Protein kinases-the major drug targets of the twenty-first century?
    • Cohen, P., Protein kinases-the major drug targets of the twenty-first century? Nat. Rev. Drug Discov. 2002, 1, 309-315.
    • (2002) Nat. Rev. Drug Discov. , vol.1 , pp. 309-315
    • Cohen, P.1
  • 9
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker, B., Tamura, S., Buchdunger, E., Ohno, S. et al., Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat. Med. 1996, 2, 561-566.
    • (1996) Nat. Med. , vol.2 , pp. 561-566
    • Druker, B.1    Tamura, S.2    Buchdunger, E.3    Ohno, S.4
  • 10
    • 82955201220 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the CR-ABL tyrosine kinase in chronic myeloid leukemia
    • Druker, B., Talpaz, M., Resta, D., Peng, B. et al., Efficacy and safety of a specific inhibitor of the CR-ABL tyrosine kinase in chronic myeloid leukemia. N. Engl. J. Med. 2001, 2, 561-566.
    • (2001) N. Engl. J. Med. , vol.2 , pp. 561-566
    • Druker, B.1    Talpaz, M.2    Resta, D.3    Peng, B.4
  • 11
    • 1642323740 scopus 로고    scopus 로고
    • Protein kinase inhibitors: insights into drug design from structure
    • Noble, M., Endicott, J., Johnson, L., Protein kinase inhibitors: insights into drug design from structure. Science 2004, 303, 1800-1805.
    • (2004) Science , vol.303 , pp. 1800-1805
    • Noble, M.1    Endicott, J.2    Johnson, L.3
  • 12
    • 65349122964 scopus 로고    scopus 로고
    • The current status of drug discovery against the human kinome
    • Eglen, R. M., Reisine, T., The current status of drug discovery against the human kinome. Assay Drug Dev. Tech. 2009, 7, 22-43.
    • (2009) Assay Drug Dev. Tech. , vol.7 , pp. 22-43
    • Eglen, R.M.1    Reisine, T.2
  • 13
    • 0025893168 scopus 로고    scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
    • 199
    • Liu, J., Farmer, J. D., Lane, W. S., Friedman, J. et al., Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 199, 166, 807-815.
    • Cell , vol.166 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3    Friedman, J.4
  • 14
    • 0025776523 scopus 로고
    • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
    • Heitman, J., Movva, N. R., Hall, M. N., Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 1991, 253, 905-909.
    • (1991) Science , vol.253 , pp. 905-909
    • Heitman, J.1    Movva, N.R.2    Hall, M.N.3
  • 15
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F. et al., A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372, 739-746.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3    Gallagher, T.F.4
  • 16
    • 33846280489 scopus 로고    scopus 로고
    • Phosphoproteome and kinome analysis: unique perspectives on the same problem
    • Jalal, S., Kindrachuk, J., Napper, S., Phosphoproteome and kinome analysis: unique perspectives on the same problem. Curr. Anal. Chem. 2007, 3, 1-15.
    • (2007) Curr. Anal. Chem. , vol.3 , pp. 1-15
    • Jalal, S.1    Kindrachuk, J.2    Napper, S.3
  • 18
    • 0037305895 scopus 로고    scopus 로고
    • Tackling the phosphoproteome: tools and strategies
    • Kalume, D. E., Molina, H. and Pandey, A., Tackling the phosphoproteome: tools and strategies. Curr. Opin. Chem. Biol. 2004, 7, 64-69.
    • (2004) Curr. Opin. Chem. Biol. , vol.7 , pp. 64-69
    • Kalume, D.E.1    Molina, H.2    Pandey, A.3
  • 19
    • 10644230916 scopus 로고    scopus 로고
    • Current two-dimensional electrophoresis technology for proteomics
    • Gorg, A., Weiss, W., Dunn, M. J., Current two-dimensional electrophoresis technology for proteomics. Proteomics 2004, 4, 3665-3685.
    • (2004) Proteomics , vol.4 , pp. 3665-3685
    • Gorg, A.1    Weiss, W.2    Dunn, M.J.3
  • 20
    • 0032560583 scopus 로고    scopus 로고
    • Statistical analysis of protein kinase specificity determinants
    • Kreegipuu, A., Blom, N., Brunak, S., Jarv, J., Statistical analysis of protein kinase specificity determinants. FEBS Lett. 1998, 430, 45-50.
    • (1998) FEBS Lett. , vol.430 , pp. 45-50
    • Kreegipuu, A.1    Blom, N.2    Brunak, S.3    Jarv, J.4
  • 21
    • 0033768106 scopus 로고    scopus 로고
    • Analysis of yeast protein kinases using protein chips
    • Zhu, H., Klemic, J. F., Chang, S., Bertone, P. et al., Analysis of yeast protein kinases using protein chips. Nature Genet. 2000, 26, 283-289.
    • (2000) Nature Genet. , vol.26 , pp. 283-289
    • Zhu, H.1    Klemic, J.F.2    Chang, S.3    Bertone, P.4
  • 22
    • 0043192619 scopus 로고    scopus 로고
    • Preparing protein microarrays by soft-landing of mass-selected ions
    • Ouyang, Z., Takats, Z., Blake, T. A., Gologan, B. et al., Preparing protein microarrays by soft-landing of mass-selected ions. Science 2003, 301, 1351-1354.
    • (2003) Science , vol.301 , pp. 1351-1354
    • Ouyang, Z.1    Takats, Z.2    Blake, T.A.3    Gologan, B.4
  • 23
    • 0036199649 scopus 로고    scopus 로고
    • Peptide chips for the quantitative evaluation of protein kinase activity
    • Houseman, B. T., Huh, J. H., Kron, S. J., Mrksich, M., Peptide chips for the quantitative evaluation of protein kinase activity. Nature Biotech. 2002, 20, 270-274.
    • (2002) Nature Biotech. , vol.20 , pp. 270-274
    • Houseman, B.T.1    Huh, J.H.2    Kron, S.J.3    Mrksich, M.4
  • 26
    • 10344223002 scopus 로고    scopus 로고
    • Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells
    • Diks, S. H., Kok, K., O'Toole, T., Hommes, D. W. et al., Kinome profiling for studying lipopolysaccharide signal transduction in human peripheral blood mononuclear cells. J. Biol. Chem. 2004, 279, 49206-49213.
    • (2004) J. Biol. Chem. , vol.279 , pp. 49206-49213
    • Diks, S.H.1    Kok, K.2    O'Toole, T.3    Hommes, D.W.4
  • 27
    • 79959553437 scopus 로고    scopus 로고
    • Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1
    • Turner-Brannen, E., Choi, K. G., Arsenault, R., El-Gagalwy, H. et al., Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1. J. Immunol. 2011, 186, 7127-7135.
    • (2011) J. Immunol. , vol.186 , pp. 7127-7135
    • Turner-Brannen, E.1    Choi, K.G.2    Arsenault, R.3    El-Gagalwy, H.4
  • 28
    • 77956057143 scopus 로고    scopus 로고
    • TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides
    • Booth, J. S., Arsenault, R., Napper, S., Griebel, P. J. et al., TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. J. Innate Immun. 2010, 5, 483-494.
    • (2010) J. Innate Immun. , vol.5 , pp. 483-494
    • Booth, J.S.1    Arsenault, R.2    Napper, S.3    Griebel, P.J.4
  • 29
    • 75149130051 scopus 로고    scopus 로고
    • Targeting the cancer kinome through polypharmacology
    • Knight, Z. A., Lin, H., Shokat, K. M., Targeting the cancer kinome through polypharmacology. Nat. Rev. Cancer. 2010, 10, 130-137.
    • (2010) Nat. Rev. Cancer. , vol.10 , pp. 130-137
    • Knight, Z.A.1    Lin, H.2    Shokat, K.M.3
  • 30
    • 67651006461 scopus 로고    scopus 로고
    • Kinome profiling in pediatric brain tumors as a new approach for target discovery
    • Sikkema, A. H., Diks, S. H., den Dunnen, W. F. A., ter Elst, A. et al., Kinome profiling in pediatric brain tumors as a new approach for target discovery. Cancer Res. 2009, 69, 5987-5995.
    • (2009) Cancer Res. , vol.69 , pp. 5987-5995
    • Sikkema, A.H.1    Diks, S.H.2    den Dunnen, W.F.A.3    ter Elst, A.4
  • 31
    • 78651294572 scopus 로고    scopus 로고
    • Identification of new possible targets for leukemia treatment by kinase activity profiling
    • ter Elst, A., Diks, S. H., Kampen, K. R., Hoogerbrugge, P. M. et al., Identification of new possible targets for leukemia treatment by kinase activity profiling. Leukemia Lymphoma 2011, 52, 122-130.
    • (2011) Leukemia Lymphoma , vol.52 , pp. 122-130
    • ter Elst, A.1    Diks, S.H.2    Kampen, K.R.3    Hoogerbrugge, P.M.4
  • 32
    • 68049148657 scopus 로고    scopus 로고
    • Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment
    • Schrage, Y. M., Briaire-de Bruijn, I. H., de Miranda, N. F. C. C., van Oosterwijk, J. et al., Kinome profiling of chondrosarcoma reveals SRC-pathway activity and dasatinib as option for treatment. Cancer Res. 2009, 69, 6216-6222.
    • (2009) Cancer Res. , vol.69 , pp. 6216-6222
    • Schrage, Y.M.1    Briaire-de Bruijn, I.H.2    de Miranda, N.F.C.C.3    van Oosterwijk, J.4
  • 33
    • 39449084394 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer
    • Tuynman, J. B., Vermeulen, L., Boon, E. M., Kemper, K. et al., Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer. Cancer Res. 2008, 68(4), 1213-1220.
    • (2008) Cancer Res. , vol.68 , Issue.4 , pp. 1213-1220
    • Tuynman, J.B.1    Vermeulen, L.2    Boon, E.M.3    Kemper, K.4
  • 34
    • 82955239151 scopus 로고    scopus 로고
    • Kinome profiling of bovine leukemia virus-indiced ovine leukemia: an approach for identifying altered signaling pathways and drugable targets in cancer
    • Van den Broke, A., Arsenault, R., Cleuter, Y., Dehouck, C., Kinome profiling of bovine leukemia virus-indiced ovine leukemia: an approach for identifying altered signaling pathways and drugable targets in cancer. JAIDS 2011, 56, 98.
    • (2011) JAIDS , vol.56 , pp. 98
    • Van den Broke, A.1    Arsenault, R.2    Cleuter, Y.3    Dehouck, C.4
  • 35
    • 34250819317 scopus 로고    scopus 로고
    • Kinome profiling of Arabidopsis using arrays of kinase consensus substrates
    • Ritsema, T., Joore, J., van Workum, W., Pieterse, C. J.M., Kinome profiling of Arabidopsis using arrays of kinase consensus substrates. Plant Methods 2007, 3, 3.
    • (2007) Plant Methods , vol.3 , pp. 3
    • Ritsema, T.1    Joore, J.2    van Workum, W.3    Pieterse, C.J.4
  • 37
    • 37549019652 scopus 로고    scopus 로고
    • Use of animal models in the development of human vaccines
    • Gerdts, V., van den Hurk, S., Griebel, P., Babiuk, L., Use of animal models in the development of human vaccines. Future Med. 2007, 2, 667-675.
    • (2007) Future Med. , vol.2 , pp. 667-675
    • Gerdts, V.1    van den Hurk, S.2    Griebel, P.3    Babiuk, L.4
  • 38
    • 0032608485 scopus 로고    scopus 로고
    • Genetic effects on vaccination
    • Wilkie, B. N., Mallard, B. A., Genetic effects on vaccination. Adv. Vet. Med. 1999, 41, 39-51.
    • (1999) Adv. Vet. Med. , vol.41 , pp. 39-51
    • Wilkie, B.N.1    Mallard, B.A.2
  • 39
    • 34447092208 scopus 로고    scopus 로고
    • Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies
    • Wilson, K. T., Crabtree, J. E., Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies. Gastroenterology 2007, 133, 288-308.
    • (2007) Gastroenterology , vol.133 , pp. 288-308
    • Wilson, K.T.1    Crabtree, J.E.2
  • 40
    • 55949099266 scopus 로고    scopus 로고
    • The properties and functions of virus encoded microRNA, siRNA, and other small noncoding RNAs
    • He, S., Yang, Z., Skogerbo, G., Ren, F. et al., The properties and functions of virus encoded microRNA, siRNA, and other small noncoding RNAs. CRC Crit. Rev. Microbiol. 2008, 34, 175-188.
    • (2008) CRC Crit. Rev. Microbiol. , vol.34 , pp. 175-188
    • He, S.1    Yang, Z.2    Skogerbo, G.3    Ren, F.4
  • 41
    • 61849083039 scopus 로고    scopus 로고
    • Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A
    • Hilhorst, R., Houkes, L., van den Berg, A., Ruijtenbeek, R., Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterization, and inhibition studies on protein kinase A. Anal. Biochem. 2009, 387, 150-161.
    • (2009) Anal. Biochem. , vol.387 , pp. 150-161
    • Hilhorst, R.1    Houkes, L.2    van den Berg, A.3    Ruijtenbeek, R.4
  • 42
    • 71049127324 scopus 로고    scopus 로고
    • Nuclear receptor coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor y cofactor
    • Koppen, A., Houtman, R., Pijnenburg, D., Jeninga, E. H. et al., Nuclear receptor coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor y cofactor. Mol. Cell. Proteomics 2009, 8, 2212-2226.
    • (2009) Mol. Cell. Proteomics , vol.8 , pp. 2212-2226
    • Koppen, A.1    Houtman, R.2    Pijnenburg, D.3    Jeninga, E.H.4
  • 43
    • 70349559624 scopus 로고    scopus 로고
    • Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays
    • Poot, A. J., van Ameijde, J., Slijper, M., van den Berg, A. et al., Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays. ChemBioChem 2009, 10, 2042-2051.
    • (2009) ChemBioChem , vol.10 , pp. 2042-2051
    • Poot, A.J.1    van Ameijde, J.2    Slijper, M.3    van den Berg, A.4
  • 44
    • 77952133664 scopus 로고    scopus 로고
    • A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells
    • Sylvester, J. E., Kron, S. J., A bead-based activity screen for small-molecule inhibitors of signal transduction in chronic myelogenous leukemia cells. Mol. Cancer Ther. 2010, 9, 1469-1481.
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 1469-1481
    • Sylvester, J.E.1    Kron, S.J.2
  • 45
    • 77955968198 scopus 로고    scopus 로고
    • Peptide reporters of kinase activity in whole cell lysates
    • Wu, D., Sylvester, J. E., Parker, L. L., Zhou, G., Kron, S. J., Peptide reporters of kinase activity in whole cell lysates. Biopolymers 2010, 94, 475-486.
    • (2010) Biopolymers , vol.94 , pp. 475-486
    • Wu, D.1    Sylvester, J.E.2    Parker, L.L.3    Zhou, G.4    Kron, S.J.5
  • 46
    • 0017078844 scopus 로고
    • The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver
    • Zetterqvist, O., Ragnarsson, U., Humble, E., Berglund, L., Engstrom, L., The minimum substrate of cyclic AMP-stimulated protein kinase, as studied by synthetic peptides representing the phosphorylatable site of pyruvate kinase (type L) of rat liver. Biochem. Biophys. Res. Commun. 1976, 70, 696-703.
    • (1976) Biochem. Biophys. Res. Commun. , vol.70 , pp. 696-703
    • Zetterqvist, O.1    Ragnarsson, U.2    Humble, E.3    Berglund, L.4    Engstrom, L.5
  • 47
    • 0017638132 scopus 로고
    • Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase
    • Kemp, B. E., Graves, D. J., Benjamini, E., Krebs, E. G., Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase. J. Biol. Chem. 1977, 252, 4888-4894.
    • (1977) J. Biol. Chem. , vol.252 , pp. 4888-4894
    • Kemp, B.E.1    Graves, D.J.2    Benjamini, E.3    Krebs, E.G.4
  • 48
    • 77950842431 scopus 로고    scopus 로고
    • Kinome profiling of clinical cancer specimens
    • Parikh, K., Peppelenbosch, M. P., Kinome profiling of clinical cancer specimens. Cancer Res. 2010, 70, 2575.
    • (2010) Cancer Res. , vol.70 , pp. 2575
    • Parikh, K.1    Peppelenbosch, M.P.2
  • 49
    • 0344812247 scopus 로고
    • Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
    • Benovic, J. L., Strasser, R. H., Caron, M. G., Lefkowitz, R. J., Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc. Natl. Acad. Sci. USA 1986, 83, 2797-2801.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2797-2801
    • Benovic, J.L.1    Strasser, R.H.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 50
    • 0022973987 scopus 로고
    • Beta-agonist and prostaglandin EI-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors
    • Strasser, R. H., Benovic, J. L., Caron, M. G., Lefkowitz, R. J., Beta-agonist and prostaglandin EI-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors. Proc. Natl. Acad. Sci. USA 1986, 83, 6362-6366.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 6362-6366
    • Strasser, R.H.1    Benovic, J.L.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 51
    • 0022641020 scopus 로고
    • Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase
    • Benovic, J. L., Mayor, F., Somers, R. L., Caron, M. G., Leftowitz, R. J., Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase. Nature 1986, 321, 869-872.
    • (1986) Nature , vol.321 , pp. 869-872
    • Benovic, J.L.1    Mayor, F.2    Somers, R.L.3    Caron, M.G.4    Leftowitz, R.J.5
  • 52
    • 0041926731 scopus 로고    scopus 로고
    • Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling
    • Pouyssegur, J., Lenormand, P., Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Eur. J. Biochem. 2003, 270, 3291-3299.
    • (2003) Eur. J. Biochem. , vol.270 , pp. 3291-3299
    • Pouyssegur, J.1    Lenormand, P.2
  • 53
    • 0037127263 scopus 로고    scopus 로고
    • Transforming growth factor beta1 regulates Kir2.3 inward rectifier K+channels via phospholipase C and protein kinase C gamma in reactive astrocytes from adult rat brain
    • Perillan, P. R., Chen, M., Potts, E. A., Simard, J. M., Transforming growth factor beta1 regulates Kir2.3 inward rectifier K+channels via phospholipase C and protein kinase C gamma in reactive astrocytes from adult rat brain. J. Biol. Chem. 2001, 227, 1974-1980.
    • (2001) J. Biol. Chem. , vol.227 , pp. 1974-1980
    • Perillan, P.R.1    Chen, M.2    Potts, E.A.3    Simard, J.M.4
  • 54
    • 0034794309 scopus 로고    scopus 로고
    • Targeting of protein kinase C gamma to mitochondria in the oxidative stress response
    • Majumder, P. K., Mishra, N. C., Sun, X., Bharti, A. et al., Targeting of protein kinase C gamma to mitochondria in the oxidative stress response. Cell Growth Differ. 2001, 12, 465-470.
    • (2001) Cell Growth Differ. , vol.12 , pp. 465-470
    • Majumder, P.K.1    Mishra, N.C.2    Sun, X.3    Bharti, A.4
  • 55
    • 0035816549 scopus 로고    scopus 로고
    • Protein kinases C translocation responses to low concentrations of arachidonic acid
    • O'Flaherty, J. T., Chadwell, B. A., Kearns, M. W., Sergeant, S., Daniel, L. W., Protein kinases C translocation responses to low concentrations of arachidonic acid. J. Biol. Chem. 2001, 276, 24743-24750.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24743-24750
    • O'Flaherty, J.T.1    Chadwell, B.A.2    Kearns, M.W.3    Sergeant, S.4    Daniel, L.W.5
  • 56
    • 0034241380 scopus 로고    scopus 로고
    • Specificity in the cAMP/PKA signalling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA
    • Skalhegg, B. S., Tasken, K., Specificity in the cAMP/PKA signalling pathway. Differential expression, regulation, and subcellular localization of subunits of PKA. Front Biosci. 2000, 5, d679-d693.
    • (2000) Front Biosci. , vol.5
    • Skalhegg, B.S.1    Tasken, K.2
  • 57
    • 70549105132 scopus 로고    scopus 로고
    • Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases
    • Alber, T., Signaling mechanisms of the Mycobacterium tuberculosis receptor Ser/Thr protein kinases. Curr. Opin. Struct. Biol. 2009, 6, 650-657.
    • (2009) Curr. Opin. Struct. Biol. , vol.6 , pp. 650-657
    • Alber, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.