-
1
-
-
0012473279
-
The nuclear receptor super-family: The second decade
-
Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., and Evans, R. M. (1995) The nuclear receptor superfamily: the second decade. Cell 83, 835-839 (Pubitemid 126663112)
-
(1995)
Cell
, vol.83
, Issue.6
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
2
-
-
0342616837
-
A canonical structure for the ligand-binding domain of nuclear receptors
-
Wurtz, J. M., Bourguet, W., Renaud, J. P., Vivat, V., Chambon, P., Moras, D., and Gronemeyer, H. (1996) A canonical structure for the ligand-binding domain of nuclear receptors. Nat. Struct. Biol. 3, 87-94
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 87-94
-
-
Wurtz, J.M.1
Bourguet, W.2
Renaud, J.P.3
Vivat, V.4
Chambon, P.5
Moras, D.6
Gronemeyer, H.7
-
3
-
-
8844262660
-
Principles for modulation of the nuclear receptor superfamily
-
Gronemeyer, H., Gustafsson, J. A., and Laudet, V. (2004) Principles for modulation of the nuclear receptor superfamily. Nat. Rev. Drug Discov. 3, 950-964
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 950-964
-
-
Gronemeyer, H.1
Gustafsson, J.A.2
Laudet, V.3
-
4
-
-
34548252291
-
Nuclear receptor coregulators: Judges, juries, and executioners of cellular regulation
-
Lonard, D. M., and O'malley, B. W. (2007) Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol. Cell 27, 691-700
-
(2007)
Mol. Cell
, vol.27
, pp. 691-700
-
-
Lonard, D.M.1
O'Malley, B.W.2
-
5
-
-
0035813090
-
Coregulator codes of transcriptional regulation by nuclear receptors
-
Rosenfeld, M. G., and Glass, C. K. (2001) Coregulator codes of transcriptional regulation by nuclear receptors. J. Biol. Chem. 276, 36865-36868
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36865-36868
-
-
Rosenfeld, M.G.1
Glass, C.K.2
-
6
-
-
0030986236
-
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
-
DOI 10.1038/42750
-
Heery, D. M., Kalkhoven, E., Hoare, S., and Parker, M. G. (1997) A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387, 733-736 (Pubitemid 27270617)
-
(1997)
Nature
, vol.387
, Issue.6634
, pp. 733-736
-
-
Heery, D.M.1
Kalkhoven, E.2
Hoare, S.3
Parker, M.G.4
-
7
-
-
0033523917
-
The CoRNR motif controls the recruitment of compressors by nuclear hormone receptors
-
DOI 10.1038/47069
-
Hu, X., and Lazar, M. A. (1999) The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors. Nature 402, 93-96 (Pubitemid 29533522)
-
(1999)
Nature
, vol.402
, Issue.6757
, pp. 93-96
-
-
Hu, X.1
Lazar, M.A.2
-
8
-
-
13244295627
-
The LxxLL motif: A multifunctional binding sequence in transcriptional regulation
-
Plevin, M. J., Mills, M. M., and Ikura, M. (2005) The LxxLL motif: a multifunctional binding sequence in transcriptional regulation. Trends Biochem. Sci. 30, 66-69
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 66-69
-
-
Plevin, M.J.1
Mills, M.M.2
Ikura, M.3
-
9
-
-
33644645013
-
PPAR delta: A dagger in the heart of the metabolic syndrome
-
Barish, G. D., Narkar, V. A., and Evans, R. M. (2006) PPAR delta: a dagger in the heart of the metabolic syndrome. J. Clin. Investig. 116, 590-597
-
(2006)
J. Clin. Investig.
, vol.116
, pp. 590-597
-
-
Barish, G.D.1
Narkar, V.A.2
Evans, R.M.3
-
10
-
-
33644652183
-
Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
-
Lefebvre, P., Chinetti, G., Fruchart, J. C., and Staels, B. (2006) Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J. Clin. Investig. 116, 571-580
-
(2006)
J. Clin. Investig.
, vol.116
, pp. 571-580
-
-
Lefebvre, P.1
Chinetti, G.2
Fruchart, J.C.3
Staels, B.4
-
11
-
-
0344375097
-
Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
-
DOI 10.2337/diabetes.52.4.910
-
Savage, D. B., Tan, G. D., Acerini, C. L. Jebb, S. A., Agostini, M., Gurnell, M., Williams, R. L., Umpleby, A. M., Thomas, E. L., Bell, J. D., Dixon, A. K., Dunne, F., Boiani, R., Cinti, S., Vidal-Puig, A., Karpe, F., Chatterjee, V. K., and O'Rahilly, S. (2003) Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. Diabetes 52, 910-917 (Pubitemid 36384259)
-
(2003)
Diabetes
, vol.52
, Issue.4
, pp. 910-917
-
-
Savage, D.B.1
Tan, G.D.2
Acerini, C.L.3
Jebb, S.A.4
Agostini, M.5
Gurnell, M.6
Williams, R.L.7
Umpleby, A.M.8
Thomas, E.L.9
Bell, J.D.10
Dixon, A.K.11
Dunne, F.12
Boiani, R.13
Cinti, S.14
Vidal-Puig, A.15
Karpe, F.16
Chatterjee, V.K.V.17
O'Rahilly, S.18
-
12
-
-
28944446431
-
The many faces of PPARgamma
-
Lehrke, M., and Lazar, M. A. (2005) The many faces of PPARgamma. Cell 123, 993-999
-
(2005)
Cell
, vol.123
, pp. 993-999
-
-
Lehrke, M.1
Lazar, M.A.2
-
13
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARgamma
-
Tontonoz, P., and Spiegelman, B. M. (2008) Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289-312
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
14
-
-
34648832073
-
Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: A meta-analysis of randomised clinical trials
-
Lago, R. M., Singh, P. P., and Nesto, R. W. (2007) Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical trials. Lancet 370, 1129-1136
-
(2007)
Lancet
, vol.370
, pp. 1129-1136
-
-
Lago, R.M.1
Singh, P.P.2
Nesto, R.W.3
-
15
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen, S. E., and Wolski, K. (2007) Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N. Engl. J. Med. 356, 2457-2471
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
16
-
-
10644251916
-
Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: Lessons from genetics and pharmacology
-
Knouff, C., and Auwerx, J. (2004) Peroxisome proliferator-activated receptor-gamma calls for activation in moderation: lessons from genetics and pharmacology. Endocr. Rev. 25, 899-918
-
(2004)
Endocr. Rev.
, vol.25
, pp. 899-918
-
-
Knouff, C.1
Auwerx, J.2
-
17
-
-
42749100646
-
Selective modulators of PPAR-gamma activity: Molecular aspects related to obesity and side-effects
-
Zhang, F., Lavan, B. E., and Gregoire, F. M. (2007) Selective modulators of PPAR-gamma activity: molecular aspects related to obesity and side-effects. PPAR Res. 2007, 32696
-
(2007)
PPAR Res.
, vol.2007
, pp. 32696
-
-
Zhang, F.1
Lavan, B.E.2
Gregoire, F.M.3
-
18
-
-
37349114118
-
Nuclear receptors: Decoding metabolic disease
-
DOI 10.1016/j.febslet.2007.11.016, PII S001457930701160X
-
Sonoda, J., Pei, L., and Evans, R. M. (2008) Nuclear receptors: decoding metabolic disease. FEBS Lett. 582, 2-9 (Pubitemid 350297241)
-
(2008)
FEBS Letters
, vol.582
, Issue.1
, pp. 2-9
-
-
Sonoda, J.1
Pei, L.2
Evans, R.M.3
-
19
-
-
34848834842
-
RAR and RXR modulation in cancer and metabolic disease
-
Altucci, L., Leibowitz, M. D., Ogilvie, K. M., de Lera, A. R., and Gronemeyer, H. (2007) RAR and RXR modulation in cancer and metabolic disease. Nat. Rev. Drug Discov. 6, 793-810
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 793-810
-
-
Altucci, L.1
Leibowitz, M.D.2
Ogilvie, K.M.3
De Lera, A.R.4
Gronemeyer, H.5
-
20
-
-
33845929000
-
Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer
-
Jordan, V. C., and Brodie, A. M. (2007) Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer. Steroids 72, 7-25
-
(2007)
Steroids
, vol.72
, pp. 7-25
-
-
Jordan, V.C.1
Brodie, A.M.2
-
21
-
-
34548535239
-
Functional peptide arrays for high-throughput chemical biology based applications
-
Henderson, G., and Bradley, M. (2007) Functional peptide arrays for high-throughput chemical biology based applications. Curr. Opin. Biotechnol. 18, 326-330
-
(2007)
Curr. Opin. Biotechnol.
, vol.18
, pp. 326-330
-
-
Henderson, G.1
Bradley, M.2
-
22
-
-
0034007387
-
A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis
-
Gurnell, M., Wentworth, J. M., Agostini, M., Adams, M., Collingwood, T. N., Provenzano, C., Browne, P. O., Rajanayagam, O., Burris, T. P., Schwabe, J. W., Lazar, M. A., and Chatterjee, V. K. (2000) A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis. J. Biol. Chem. 275, 5754-5759
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5754-5759
-
-
Gurnell, M.1
Wentworth, J.M.2
Agostini, M.3
Adams, M.4
Collingwood, T.N.5
Provenzano, C.6
Browne, P.O.7
Rajanayagam, O.8
Burris, T.P.9
Schwabe, J.W.10
Lazar, M.A.11
Chatterjee, V.K.12
-
23
-
-
34250831418
-
Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy
-
Jeninga, E. H., van Beekum, O., van Dijk, A. D., Hamers, N., Hendriks-Stegeman, B. I., Bonvin, A. M., Berger, R., and Kalkhoven, E. (2007) Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy. Mol. Endocrinol. 21, 1049-1065
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 1049-1065
-
-
Jeninga, E.H.1
Van Beekum, O.2
Van Dijk, A.D.3
Hamers, N.4
Hendriks-Stegeman, B.I.5
Bonvin, A.M.6
Berger, R.7
Kalkhoven, E.8
-
24
-
-
0028972025
-
15-deoxy-delta12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARgamma
-
DOI 10.1016/0092-8674(95)90193-0
-
Forman, B. M., Tontonoz, P., Chen, J., Brun, R. P., Spiegelman, B. M., and Evans, R. M. (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 83, 803-812 (Pubitemid 3006324)
-
(1995)
Cell
, vol.83
, Issue.5
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
25
-
-
0032472408
-
Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor
-
DOI 10.1093/emboj/17.1.232
-
Kalkhoven, E., Valentine, J. E., Heery, D. M., and Parker, M. G. (1998) Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor. EMBO J. 17, 232-243 (Pubitemid 28041064)
-
(1998)
EMBO Journal
, vol.17
, Issue.1
, pp. 232-243
-
-
Kalkhoven, E.1
Valentine, J.E.2
Heery, D.M.3
Parker, M.G.4
-
26
-
-
0033977890
-
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
-
Vega, R. B., Huss, J. M., and Kelly, D. P. (2000) The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes. Mol. Cell. Biol. 20, 1868-1876
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1868-1876
-
-
Vega, R.B.1
Huss, J.M.2
Kelly, D.P.3
-
27
-
-
41549153833
-
The adipogenic acetyltransferase Tip60 targets activation function 1 of PPARgamma
-
van Beekum, O., Brenkman, A. B., Grøntved, L., Hamers, N., van den Broek, N. J., Berger, R., Mandrup, S., and Kalkhoven, E. (2008) The adipogenic acetyltransferase Tip60 targets activation function 1 of PPARgamma. Endocrinology 149, 1840-1849
-
(2008)
Endocrinology
, vol.149
, pp. 1840-1849
-
-
Van Beekum, O.1
Brenkman, A.B.2
Grøntved, L.3
Hamers, N.4
Van Den Broek, N.J.5
Berger, R.6
Mandrup, S.7
Kalkhoven, E.8
-
28
-
-
38349031676
-
Protein-tyrosine kinase activity profiling in knock down Zebrafish embryos
-
DOI 10.1371/journal.pone.0000581
-
Lemeer, S., Jopling, C., Naji, F., Ruijtenbeek, R., Slijper, M., Heck, A. J., and den Hertog, J. (2007) Protein-tyrosine kinase activity profiling in knock down zebrafish embryos. PLoS ONE 2, e581 (Pubitemid 351260405)
-
(2007)
PLoS ONE
, vol.2
, Issue.7
-
-
Lemeer, S.1
Jopling, C.2
Naji, F.3
Ruijtenbeek, R.4
Slijper, M.5
Heck, A.J.R.6
Den Hertog, J.7
-
29
-
-
38349076660
-
Endogenous phosphotyrosine signaling in zebrafish embryos
-
Lemeer, S., Ruijtenbeek, R., Pinkse, M. W., Jopling, C., Heck, A. J., den Hertog, J., and Slijper, M. (2007) Endogenous phosphotyrosine signaling in zebrafish embryos. Mol. Cell. Proteomics 6, 2088-2099
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 2088-2099
-
-
Lemeer, S.1
Ruijtenbeek, R.2
Pinkse, M.W.3
Jopling, C.4
Heck, A.J.5
Den Hertog, J.6
Slijper, M.7
-
30
-
-
61849083039
-
Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterisation and inhibition studies on protein kinase A
-
Hilhorst, R., Houkes, L., van den Berg, A., and Ruijtenbeek, R. (2009) Peptide microarrays for detailed, high-throughput substrate identification, kinetic characterisation and inhibition studies on protein kinase A. Anal. Biochem. 387, 150-161
-
(2009)
Anal. Biochem.
, vol.387
, pp. 150-161
-
-
Hilhorst, R.1
Houkes, L.2
Van Den Berg, A.3
Ruijtenbeek, R.4
-
31
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995) An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270, 12953-12956
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
32
-
-
0033998334
-
The PPARs: From orphan receptors to drug discovery
-
Willson, T. M., Brown, P. J., Sternbach, D. D., and Henke, B. R. (2000) The PPARs: from orphan receptors to drug discovery. J. Med. Chem. 43, 527-550
-
(2000)
J. Med. Chem.
, vol.43
, pp. 527-550
-
-
Willson, T.M.1
Brown, P.J.2
Sternbach, D.D.3
Henke, B.R.4
-
33
-
-
33644672013
-
Molecular characterization of new selective peroxisome proliferator- Activated receptor gamma modulators with angiotensin receptor blocking activity
-
DOI 10.2337/diabetes.54.12.3442
-
Schupp, M., Clemenz, M., Gineste, R., Witt, H., Janke, J., Helleboid, S., Hennuyer, N., Ruiz, P., Unger, T., Staels, B., and Kintscher, U. (2005) Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity. Diabetes 54, 3442-3452 (Pubitemid 43334334)
-
(2005)
Diabetes
, vol.54
, Issue.12
, pp. 3442-3452
-
-
Schupp, M.1
Clemenz, M.2
Gineste, R.3
Witt, H.4
Janke, J.5
Helleboid, S.6
Hennuyer, N.7
Ruiz, P.8
Unger, T.9
Staels, B.10
Kintscher, U.11
-
34
-
-
0036146384
-
A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy
-
Agarwal, A. K., and Garg, A. (2002) A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy. J. Clin. Endocrinol. Metab. 87, 408-411
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 408-411
-
-
Agarwal, A.K.1
Garg, A.2
-
35
-
-
33744497272
-
The peroxisome proliferator-activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis
-
Hummasti, S., and Tontonoz, P. (2006) The peroxisome proliferator- activated receptor N-terminal domain controls isotype-selective gene expression and adipogenesis. Mol. Endocrinol. 20, 1261-1275
-
(2006)
Mol. Endocrinol.
, vol.20
, pp. 1261-1275
-
-
Hummasti, S.1
Tontonoz, P.2
-
36
-
-
33746547216
-
Peroxisome proliferator-activated receptor subtype- And cell-type-specific activation of genomic target genes upon adenoviral transgene delivery
-
Nielsen, R., Grøntved, L., Stunnenberg, H. G., and Mandrup, S. (2006) Peroxisome proliferator-activated receptor subtype- and cell-type-specific activation of genomic target genes upon adenoviral transgene delivery. Mol. Cell. Biol. 26, 5698-5714
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5698-5714
-
-
Nielsen, R.1
Grøntved, L.2
Stunnenberg, H.G.3
Mandrup, S.4
-
37
-
-
0037453718
-
Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity
-
DOI 10.1016/S0092-8674(03)00269-1
-
Wang, Y. X., Lee, C. H., Tiep, S., Yu, R. T., Ham, J., Kang, H., and Evans, R. M. (2003) Peroxisome-proliferator-activated receptor delta activates fat metabolism to prevent obesity. Cell 113, 159-170 (Pubitemid 36514968)
-
(2003)
Cell
, vol.113
, Issue.2
, pp. 159-170
-
-
Wang, Y.-X.1
Lee, C.-H.2
Tiep, S.3
Yu, R.T.4
Ham, J.5
Kang, H.6
Evans, R.M.7
-
38
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
DOI 10.1016/S0092-8674(00)81410-5
-
Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., and Spiegelman, B. M. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92, 829-839 (Pubitemid 28155321)
-
(1998)
Cell
, vol.92
, Issue.6
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
39
-
-
0028876893
-
Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor
-
Lee, J. W., Choi, H. S., Gyuris, J., Brent, R., and Moore, D. D. (1995) Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Mol. Endocrinol. 9, 243-254
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 243-254
-
-
Lee, J.W.1
Choi, H.S.2
Gyuris, J.3
Brent, R.4
Moore, D.D.5
-
40
-
-
0036224247
-
Thyroid hormone receptor interacting protein 3 (trip3) is a novel coactivator of hepatocyte nuclear factor-4alpha
-
Iwahashi, H., Yamagata, K., Yoshiuchi, I., Terasaki, J., Yang, Q., Fukui, K., Ihara, A., Zhu, Q., Asakura, T., Cao, Y., Imagawa, A., Namba, M., Hanafusa, T., Miyagawa, J., and Matsuzawa, Y. (2002) Thyroid hormone receptor interacting protein 3 (trip3) is a novel coactivator of hepatocyte nuclear factor-4alpha. Diabetes 51, 910-914
-
(2002)
Diabetes
, vol.51
, pp. 910-914
-
-
Iwahashi, H.1
Yamagata, K.2
Yoshiuchi, I.3
Terasaki, J.4
Yang, Q.5
Fukui, K.6
Ihara, A.7
Zhu, Q.8
Asakura, T.9
Cao, Y.10
Imagawa, A.11
Namba, M.12
Hanafusa, T.13
Miyagawa, J.14
Matsuzawa, Y.15
-
41
-
-
33846209597
-
Analysis of ligand-dependent recruitment of coactivator peptides to RXRbeta in a time-resolved fluorescence resonance energy transfer assay
-
Stafslien, D. K., Vedvik, K. L., De Rosier, T., and Ozers, M. S. (2007) Analysis of ligand-dependent recruitment of coactivator peptides to RXRbeta in a time-resolved fluorescence resonance energy transfer assay. Mol. Cell. Endocrinol. 264, 82-89
-
(2007)
Mol. Cell. Endocrinol.
, vol.264
, pp. 82-89
-
-
Stafslien, D.K.1
Vedvik, K.L.2
De Rosier, T.3
Ozers, M.S.4
-
42
-
-
33748468022
-
Development of a coactivator displacement assay for the orphan receptor estrogen-related receptor-gamma using time-resolved fluorescence resonance energy transfer
-
Gowda, K., Marks, B. D., Zielinski, T. K., and Ozers, M. S. (2006) Development of a coactivator displacement assay for the orphan receptor estrogen-related receptor-gamma using time-resolved fluorescence resonance energy transfer. Anal. Biochem. 357, 105-115
-
(2006)
Anal. Biochem.
, vol.357
, pp. 105-115
-
-
Gowda, K.1
Marks, B.D.2
Zielinski, T.K.3
Ozers, M.S.4
-
43
-
-
33845966382
-
The use of in vitro peptide binding profiles and in silico ligand-receptor interaction profiles to describe ligand-induced conformations of the retinoid X receptor alpha ligand-binding domain
-
Folkertsma, S., van Noort, P. I., de Heer, A., Carati, P., Brandt, R., Visser, A., Vriend, G., and de Vlieg, J. (2007) The use of in vitro peptide binding profiles and in silico ligand-receptor interaction profiles to describe ligand-induced conformations of the retinoid X receptor alpha ligand-binding domain. Mol. Endocrinol. 21, 30-48
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 30-48
-
-
Folkertsma, S.1
Van Noort, P.I.2
De Heer, A.3
Carati, P.4
Brandt, R.5
Visser, A.6
Vriend, G.7
De Vlieg, J.8
-
44
-
-
0034802615
-
Use of homogeneous time-resolved fluorescence energy transfer in the measurement of nuclear receptor activation
-
DOI 10.1006/meth.2001.1215
-
Zhou, G., Cummings, R., Hermes, J., and Moller, D. E. (2001) Use of homogeneous time-resolved fluorescence energy transfer in the measurement of nuclear receptor activation. Methods 25, 54-61 (Pubitemid 32905288)
-
(2001)
Methods
, vol.25
, Issue.1
, pp. 54-61
-
-
Zhou, G.1
Cummings, R.2
Hermes, J.3
Moller, D.E.4
-
45
-
-
0035421857
-
Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres
-
Iannone, M. A., Consler, T. G., Pearce, K. H., Stimmel, J. B., Parks, D. J., and Gray, J. G. (2001) Multiplexed molecular interactions of nuclear receptors using fluorescent microspheres. Cytometry 44, 326-337
-
(2001)
Cytometry
, vol.44
, pp. 326-337
-
-
Iannone, M.A.1
Consler, T.G.2
Pearce, K.H.3
Stimmel, J.B.4
Parks, D.J.5
Gray, J.G.6
-
46
-
-
2342648921
-
Correlation between in vitro peptide binding profiles and cellular activities for estrogen receptor-modulating compounds
-
Iannone, M. A., Simmons, C. A., Kadwell, S. H., Svoboda, D. L., Vanderwall, D. E., Deng, S. J., Consler, T. G., Shearin, J., Gray, J. G., and Pearce, K. H. (2004) Correlation between in vitro peptide binding profiles and cellular activities for estrogen receptor-modulating compounds. Mol. Endocrinol. 18, 1064-1081
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 1064-1081
-
-
Iannone, M.A.1
Simmons, C.A.2
Kadwell, S.H.3
Svoboda, D.L.4
Vanderwall, D.E.5
Deng, S.J.6
Consler, T.G.7
Shearin, J.8
Gray, J.G.9
Pearce, K.H.10
-
47
-
-
0033618510
-
Peptide antagonists of the human estrogen receptor
-
Norris, J. D., Paige, L. A., Christensen, D. J., Chang, C. Y., Huacani, M. R., Fan, D., Hamilton, P. T., Fowlkes, D. M., and McDonnell, D. P. (1999) Peptide antagonists of the human estrogen receptor. Science 285, 744-746 (Pubitemid 129505079)
-
(1999)
Science
, vol.285
, Issue.5428
, pp. 744-746
-
-
Norris, J.D.1
Paige, L.A.2
Christensen, D.J.3
Chang, C.-Y.4
Huacani, M.R.5
Fan, D.6
Hamilton, P.T.7
Fowlkes, D.M.8
McDonnell, D.P.9
-
48
-
-
0034465495
-
Selection of estrogen receptor beta- And thyroid hormone receptor beta-specific coactivator-mimetic peptides using recombinant peptide libraries
-
Northrop, J. P., Nguyen, D., Piplani, S., Olivan, S. E., Kwan, S. T., Go, N. F., Hart, C. P., and Schatz, P. J. (2000) Selection of estrogen receptor beta- and thyroid hormone receptor beta-specific coactivator-mimetic peptides using recombinant peptide libraries. Mol. Endocrinol. 14, 605-622
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 605-622
-
-
Northrop, J.P.1
Nguyen, D.2
Piplani, S.3
Olivan, S.E.4
Kwan, S.T.5
Go, N.F.6
Hart, C.P.7
Schatz, P.J.8
-
49
-
-
2642544810
-
Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta
-
Paige, L. A., Christensen, D. J., Grøn, H., Norris, J. D., Gottlin, E. B., Padilla, K. M., Chang, C. Y., Ballas, L. M., Hamilton, P. T., McDonnell, D. P., and Fowlkes, D. M. (1999) Estrogen receptor (ER) modulators each induce distinct conformational changes in ER alpha and ER beta. Proc. Natl. Acad. Sci. U.S.A. 96, 3999-4004
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 3999-4004
-
-
Paige, L.A.1
Christensen, D.J.2
Grøn, H.3
Norris, J.D.4
Gottlin, E.B.5
Padilla, K.M.6
Chang, C.Y.7
Ballas, L.M.8
Hamilton, P.T.9
McDonnell, D.P.10
Fowlkes, D.M.11
-
50
-
-
34948830554
-
The nuclear receptor-coactivator interaction surface as a target for Peptide antagonists of the peroxisome proliferator-activated receptors
-
Mettu, N. B., Stanley, T. B., Dwyer, M. A., Jansen, M. S., Allen, J. E., Hall, J. M., and McDonnell, D. P. (2007) The nuclear receptor-coactivator interaction surface as a target for Peptide antagonists of the peroxisome proliferator-activated receptors. Mol. Endocrinol. 21, 2361-2377
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2361-2377
-
-
Mettu, N.B.1
Stanley, T.B.2
Dwyer, M.A.3
Jansen, M.S.4
Allen, J.E.5
Hall, J.M.6
McDonnell, D.P.7
-
51
-
-
34249654613
-
An improved high throughput protein-protein interaction assay for nuclear hormone receptors
-
Goodson, M. L., Farboud, B., and Privalsky, M. L. (2007) An improved high throughput protein-protein interaction assay for nuclear hormone receptors. Nucl. Recept. Signal. 5, e002
-
(2007)
Nucl. Recept. Signal.
, vol.5
-
-
Goodson, M.L.1
Farboud, B.2
Privalsky, M.L.3
-
52
-
-
14944383217
-
Automated yeast two-hybrid screening for nuclear receptor-interacting proteins
-
Albers, M:, Kranz, H., Kober, I., Kaiser, C., Klink, M., Suckow, J., Kern, R., and Koegl, M. (2005) Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol. Cell. Proteomics 4, 205-213
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 205-213
-
-
Albers, M.1
Kranz, H.2
Kober, I.3
Kaiser, C.4
Klink, M.5
Suckow, J.6
Kern, R.7
Koegl, M.8
-
53
-
-
15944408802
-
A proteomic microarray approach for exploring ligand-initiated nuclear hormone receptor pharmacology, receptor selectivity, and heterodimer functionality
-
Kim, S. H., Tamrazi, A., Carlson, K. E., and Katzenellenbogen, J. A. (2005) A proteomic microarray approach for exploring ligand-initiated nuclear hormone receptor pharmacology, receptor selectivity, and heterodimer functionality. Mol. Cell. Proteomics 4, 267-277
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 267-277
-
-
Kim, S.H.1
Tamrazi, A.2
Carlson, K.E.3
Katzenellenbogen, J.A.4
-
54
-
-
33845904405
-
Chemoprevention of breast cancer with selective oestrogen-receptor modulators
-
Jordan, V. C. (2007) Chemoprevention of breast cancer with selective oestrogen-receptor modulators. Nat. Rev. Cancer 7, 46-53
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 46-53
-
-
Jordan, V.C.1
-
55
-
-
34948854285
-
SERMs for the treatment and prevention of breast cancer
-
Swaby, R. F., Sharma, C. G., and Jordan, V. C. (2007) SERMs for the treatment and prevention of breast cancer. Rev. Endocr. Metab. Disord. 8, 229-239
-
(2007)
Rev. Endocr. Metab. Disord.
, vol.8
, pp. 229-239
-
-
Swaby, R.F.1
Sharma, C.G.2
Jordan, V.C.3
-
56
-
-
1442351143
-
Coregulator function: A key to understanding tissue specificity of selective receptor modulators
-
Smith, C. L., and O'Malley, B. W. (2004) Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr. Rev. 25, 45-71
-
(2004)
Endocr. Rev.
, vol.25
, pp. 45-71
-
-
Smith, C.L.1
O'Malley, B.W.2
-
57
-
-
0347134740
-
Human disorders caused by nuclear receptor gene mutations
-
Achermann, J. C., and Jameson, J. (2003) Human disorders caused by nuclear receptor gene mutations. Pure Appl. Chem. 75, 1785-1796
-
(2003)
Pure Appl. Chem.
, vol.75
, pp. 1785-1796
-
-
Achermann, J.C.1
Jameson, J.2
-
58
-
-
0033823170
-
Activating and inactivating hormone receptor mutations
-
Huhtaniemi, I. (2000) Activating and inactivating hormone receptor mutations. Horm. Res. 53, Suppl. 3, 9-16
-
(2000)
Horm. Res.
, vol.53
, Issue.SUPPL. 3
, pp. 9-16
-
-
Huhtaniemi, I.1
-
59
-
-
12144291700
-
Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma
-
Agostini, M., Gurnell, M., Savage, D. B., Wood, E. M., Smith, A. G., Rajanayagam, O., Games, K. T., Levinson, S. H., Xu, H. E., Schwabe, J. W., Willson, T. M., O'Rahilly, S., and Chatterjee, V. K. (2004) Tyrosine agonists reverse the molecular defects associated with dominant-negative mutations in human peroxisome proliferator-activated receptor gamma. Endocrinology 145, 1527-1538
-
(2004)
Endocrinology
, vol.145
, pp. 1527-1538
-
-
Agostini, M.1
Gurnell, M.2
Savage, D.B.3
Wood, E.M.4
Smith, A.G.5
Rajanayagam, O.6
Games, K.T.7
Levinson, S.H.8
Xu, H.E.9
Schwabe, J.W.10
Willson, T.M.11
O'Rahilly, S.12
Chatterjee, V.K.13
-
60
-
-
0026651651
-
Ty element-induced temperature-sensitive mutations of Saccharomyces cerevisiae
-
Kawakami, K., Shafer, B. K., Garfinkel, D. J., Strathern, J. N., and Nakamura, Y. (1992) Ty element-induced temperature-sensitive mutations of Saccharomyces cerevisiae. Genetics 131, 821-832
-
(1992)
Genetics
, vol.131
, pp. 821-832
-
-
Kawakami, K.1
Shafer, B.K.2
Garfinkel, D.J.3
Strathern, J.N.4
Nakamura, Y.5
-
61
-
-
34547557059
-
Solution structure of the zinc finger HIT domain in protein FON
-
DOI 10.1110/ps.062635107
-
He, F., Umehara, T., Tsuda, K., Inoue, M., Kigawa, T., Matsuda, T., Yabuki, T., Aoki, M., Seki, E., Terada, T., Shirouzu, M., Tanaka, A., Sugano, S., Muto, Y., and Yokoyama, S. (2007) Solution structure of the zinc finger HIT domain in protein FON. Protein Sci. 16, 1577-1587 (Pubitemid 47195685)
-
(2007)
Protein Science
, vol.16
, Issue.8
, pp. 1577-1587
-
-
He, F.1
Umehara, T.2
Tsuda, K.3
Inoue, M.4
Kigawa, T.5
Matsuda, T.6
Yabuki, T.7
Aoki, M.8
Seki, E.9
Terada, T.10
Shirouzu, M.11
Tanaka, A.12
Sugano, S.13
Muto, Y.14
Yokoyama, S.15
-
62
-
-
33947256308
-
Docking interactions in protein kinase and phosphatase networks
-
Reményi, A., Good, M. C., and Lim, W. A. (2006) Docking interactions in protein kinase and phosphatase networks. Curr. Opin. Struct. Biol. 16, 676-685
-
(2006)
Curr. Opin. Struct. Biol.
, vol.16
, pp. 676-685
-
-
Reményi, A.1
Good, M.C.2
Lim, W.A.3
-
63
-
-
36448949026
-
Multivalent engagement of chromatin modifications by linked binding modules
-
Ruthenburg, A. J., Li, H., Patel, D. J., and Allis, C. D. (2007) Multivalent engagement of chromatin modifications by linked binding modules. Nat. Rev. Mol. Cell Biol. 8, 983-994
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 983-994
-
-
Ruthenburg, A.J.1
Li, H.2
Patel, D.J.3
Allis, C.D.4
-
64
-
-
0033583023
-
p300 interacts with the N- And C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively
-
Gelman, L., Zhou, G., Fajas, L., Raspé, E., Fruchart, J. C., and Auwerx, J. (1999) p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively. J. Biol. Chem. 274, 7681-7688
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7681-7688
-
-
Gelman, L.1
Zhou, G.2
Fajas, L.3
Raspé, E.4
Fruchart, J.C.5
Auwerx, J.6
-
65
-
-
0030341454
-
Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma
-
Zhu, Y., Qi, C., Calandra, C., Rao, M. S., and Reddy, J. K. (1996) Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma. Gene Expr. 6, 185-195 (Pubitemid 126682834)
-
(1996)
Gene Expression
, vol.6
, Issue.3
-
-
Zhu, Y.1
Qi, C.2
Calandra, C.3
Rao, M.S.4
Reddy, J.K.5
-
66
-
-
0034721937
-
Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators
-
Kodera, Y., Takeyama, K., Murayama, A., Suzawa, M., Masuhiro, Y., and Kato, S. (2000) Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivators. J. Biol. Chem. 275, 33201-33204
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33201-33204
-
-
Kodera, Y.1
Takeyama, K.2
Murayama, A.3
Suzawa, M.4
Masuhiro, Y.5
Kato, S.6
-
67
-
-
0034607983
-
Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR
-
Zhu, Y., Kan, L., Qi, C., Kanwar, Y. S., Yeldandi, A. V., Rao, M. S., and Reddy, J. K. (2000) Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR. J. Biol. Chem. 275, 13510-13516
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13510-13516
-
-
Zhu, Y.1
Kan, L.2
Qi, C.3
Kanwar, Y.S.4
Yeldandi, A.V.5
Rao, M.S.6
Reddy, J.K.7
-
68
-
-
0030991152
-
Stoichiometric and steric principles governing repression by nuclear hormone receptors
-
Zamir, I., Zhang, J., and Lazar, M. A. (1997) Stoichiometric and steric principles governing repression by nuclear hormone receptors. Genes Dev. 11, 835-846 (Pubitemid 27175291)
-
(1997)
Genes and Development
, vol.11
, Issue.7
, pp. 835-846
-
-
Zamir, I.1
Zhang, J.2
Lazar, M.A.3
-
69
-
-
42249108359
-
The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARgamma
-
Kim, G. S., Lee, G. Y., Nedumaran, B., Park, Y. Y., Kim, K. T., Park, S. C., Lee, Y. C., Kim, J. B., and Choi, H. S. (2008) The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARgamma. Biochem. Biophys. Res. Commun. 370, 264-268
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.370
, pp. 264-268
-
-
Kim, G.S.1
Lee, G.Y.2
Nedumaran, B.3
Park, Y.Y.4
Kim, K.T.5
Park, S.C.6
Lee, Y.C.7
Kim, J.B.8
Choi, H.S.9
-
70
-
-
0037059762
-
Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation
-
Nishizawa, H., Yamagata, K., Shimomura, I., Takahashi, M., Kuriyama, H., Kishida, K., Hotta, K., Nagaretani, H., Maeda, N., Matsuda, M., Kihara, S., Nakamura, T., Nishigori, H., Tomura, H., Moore, D. D., Takeda, J., Funahashi, T., and Matsuzawa, Y. (2002) Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation. J. Biol. Chem. 277, 1586-1592
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1586-1592
-
-
Nishizawa, H.1
Yamagata, K.2
Shimomura, I.3
Takahashi, M.4
Kuriyama, H.5
Kishida, K.6
Hotta, K.7
Nagaretani, H.8
Maeda, N.9
Matsuda, M.10
Kihara, S.11
Nakamura, T.12
Nishigori, H.13
Tomura, H.14
Moore, D.D.15
Takeda, J.16
Funahashi, T.17
Matsuzawa, Y.18
-
71
-
-
0032230248
-
A regulatory role for RIP140 in nuclear receptor activation
-
Treuter, E., Albrektsen, T., Johansson, L., Leers, J., and Gustafsson, J. A. (1998) A regulatory role for RIP140 in nuclear receptor activation. Mol. Endocrinol. 12, 864-881
-
(1998)
Mol. Endocrinol.
, vol.12
, pp. 864-881
-
-
Treuter, E.1
Albrektsen, T.2
Johansson, L.3
Leers, J.4
Gustafsson, J.A.5
-
72
-
-
0030771856
-
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
-
Zhu, Y., Qi, C., Jain, S., Rao, M. S., and Reddy, J. K. (1997) Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor. J. Biol. Chem. 272, 25500-25506
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25500-25506
-
-
Zhu, Y.1
Qi, C.2
Jain, S.3
Rao, M.S.4
Reddy, J.K.5
|