HCN channelopathies: Pathophysiology in genetic epilepsy and therapeutic implications

British Journal of Pharmacology

Volumn 165, Issue 1, 2012, Pages 49-56

  Reid, Christopher A ^a   Phillips, A Marie ^a   Petrou, Steven ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

febrile seizures; HCN1; HCN2; HCN4; idiopathic generalized epilepsy; lamotrigine

Indexed keywords

ACETAZOLAMIDE; GABAPENTIN; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 1; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL 2; ION CHANNEL; LAMOTRIGINE; PROLINE; PROPOFOL; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANTICONVULSANT ACTIVITY; BRAIN DEVELOPMENT; BRAIN ELECTROPHYSIOLOGY; CHANNELOPATHY; DISEASE COURSE; DISEASE PREDISPOSITION; DRUG TARGETING; ENVIRONMENTAL FACTOR; EPILEPSY; EPILEPTIC STATE; EPILEPTOGENESIS; FEBRILE CONVULSION; FUNCTIONAL ASSESSMENT; GENE; GENE MUTATION; GENE SEQUENCE; GENERALIZED EPILEPSY; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC SUSCEPTIBILITY; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HCN1 GENE; HCN2 GENE; HUMAN; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNELOPATHY; IDIOPATHIC DISEASE; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SECOND MESSENGER;

ANTICONVULSANTS; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; EPILEPSY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HUMANS; ION CHANNELS; POTASSIUM CHANNELS;

EID: 82955184557     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01507.x     Document Type: Review

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