An impaired neocortical Ih is associated with enhanced excitability and absence epilepsy

European Journal of Neuroscience

Volumn 19, Issue 11, 2004, Pages 3048-3058

  Strauss, Ulf ^a   Kole, Maarten H P ^b   Bräuer, Anja U ^c   Pahnke, Jens ^a   Bajorat, Rika ^a   Rolfs, Arndt ^a   Nitsch, Robert ^c   Deisz, Rudolf A ^c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b GERMAN PRIMATE CENTER   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Burst discharge; Epilepsy; HCN1; Hyperpolarization activated cyclic nucleotide gated current; Patch clamp; Postsynaptic potentials; Sharp microelectrode recording; ZD7288

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; MESSENGER RNA; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENSITY; ELECTRIC CURRENT; EPILEPSY; IMMUNOHISTOCHEMISTRY; INBRED STRAIN; MALE; NEOCORTEX; NERVE CELL; NERVE CELL EXCITABILITY; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPIKE WAVE; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; BLOTTING, WESTERN; BRAIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; DRUG INTERACTIONS; ELECTRIC IMPEDANCE; EPILEPSY, ABSENCE; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; ION CHANNEL GATING; ION CHANNELS; MALE; MEMBRANE POTENTIALS; NEOCORTEX; NERVE TISSUE PROTEINS; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; PYRAMIDAL CELLS; PYRIMIDINES; RATS; RATS, INBRED STRAINS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIES SPECIFICITY;

EID: 2942747044     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0953-816X.2004.03392.x     Document Type: Article

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