Modulation of a pacemaker current through Ca2+-induced stimulation of cAMP production

Nature Neuroscience

Volumn 2, Issue 7, 1999, Pages 634-641

  Lüthi, Anita ^a   McCormick, David A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CALCIUM; CYCLIC AMP;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CORTICAL SYNCHRONIZATION; FERRET; HYPERPOLARIZATION; ION CURRENT; NEUROMODULATION; NONHUMAN; PACEMAKER; PERIODICITY; PRIORITY JOURNAL; THALAMUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM; CALMODULIN; CEREBRAL CORTEX; CYCLIC AMP; FERRETS; GUANOSINE TRIPHOSPHATE; HIPPOCAMPUS; NEURONS; PHOTOLYSIS; THALAMUS;

EID: 0033360176     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/10189     Document Type: Article

References (40)

1. Berridge, M. J. Neuronal calcium signaling. Neuron 21, 13-26 (1998).
2. Schulman, H. Protein phosphorylation in neuronal plasticity and gene expression. Curr. Opin. Neurobiol. 5, 375-381 (1995).
3. Bading, H., Ginty, D. D. & Greenberg, M. E. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260, 181-186 (1993).
4. Braun, A. P. & Schulman, H. The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annu. Rev. Physiol. 57, 417-445 (1995).
5. Onyike, C. U., Lin, A. H. & Abrams, T. W. Persistence of the interaction of calmodulin with adenylyl cyclase: implications for integration of transient calcium stimuli. J. Neurochem. 71, 1298-1306 (1998).
6. Montminy, M. Transcriptional regulation by cyclic AMP. Annu. Rev. Biochem. 66, 807-822 (1997).
7. Jonas, E. A. & Kaczmarek, L. K. Regulation of potassium channels by protein kinases. Curr. Opin. Neurobiol. 6, 318-323 (1996).
8. + current in rat hippocampal neurones. J. Physiol. (Lond.) 475, 229-239 (1994).
9. Pape, H.-C. Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annu. Rev. Physiol 58, 299-327 (1996).
10. Lüthi, A. & McCormick, D. A. H-current: properties of a neuronal and network pacemaker. Neuron 21, 9-12 (1998).
11. McCormick, D. A. & Pape, H.-C. Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. J. Physiol. (Lond) 431, 291-318 (1990).
12. Bal, T. & McCormick, D. A. What stops synchronized thalamocortical oscillations? Neuron 17, 297-308 (1996).
13. h. J. Neurophysiol. 79, 3284-3289 (1998).
14. McCormick, D. A. & Bal, T. Sleep and arousal: thalamocortical mechanisms. Annu. Rev. Neurosci. 20, 185-215 (1997).
15. von Krosigk, M., Bal, T. & McCormick, D. A. Cellular mechanisms of a synchronized oscillation in the thalamus. Science 261, 361-364 (1993).
16. h. Neuron 20, 553-563 (1998).
17. DiFrancesco, D. & Tortora, P. Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature 351, 145-147 (1991).
18. McCormick, D. A. & Pape, H.-C. Noradrenergic and serotonergic modulation of a hyperpolarization-activated cation current in thalamic relay neurones. J. Physiol. (Lond.) 431, 319-342 (1990).
19. 2+ of the hyperpolarization-activated cation current in rat thalamic neurones. J. Physiol. (Lond.) 503, 79-85 (1997).
20. Guellaen, G., Mahu, J.-L., Mavier, P., Berthelot, P. & Hanoune, J. RMI 12330 A, an inhibitor of adenylate cyclase in rat liver. Biochim. Biophys. Acta 484, 465-475 (1977).
21. Barajas-López, C. Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A. Pflugers Arch. 424, 410-415 (1993).
22. 2+ upon illumination. J. Am. Chem.Soc. 111, 7957-7968 (1989).
23. + currents in neurones: types, physiological roles and modulation. Trends Neurosci. 19, 150-154 (1996).
24. Strata, F. et al. A pacemaker current in dye-coupled hilar interneurons contributes to the generation of giant GABAergic potentials in developing hippocampus. J. Neurosci. 17, 1435-1446 (1997).
25. h. J. Neurophysiol. 77, 3145-3156 (1997).
26. Magee, J. C. Dendritic hyperpolarization-activated currents modify the integrative properties of hippocampal CA1 pyramidal neurons. J. Neurosci. 18, 7613-7624 (1998).
27. Huguenard, J. R. Low-threshold calcium currents in central nervous system neurons. Annu. Rev. Physiol. 58, 329-348 (1996).
28. Munsch, T., Budde, T. & Pape, H.-C. Voltage-activated intracellular calcium transients in thalamic relay cells and interneurons. Neuroreport 8, 2411-2418 (1997).
29. 2+-sensitive adenylyl cyclases. Adv. Second Messenger Phosphoprotein Res. 32, 23-51 (1998).
30. Sodickson, D. L. & Bean, B. P. Neurotransmitter activation of inwardly rectifying potassium current in dissociated hippocampal CA3 neurons: interactions among multiple receptors. J. Neurosci. 18, 8153-8162 (1998).
31. Beavo J. A. Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms. Physiol. Rev. 75, 725-748 (1995).
32. Matsuoka, I., Suzuki, Y., Defer, N., Nakanishi, H. & Hanoune, J. Differential expression of type I, II, and V adenylyl cyclase gene in the postnatal developing rat brain. J. Neurochem. 68, 498-506 (1997).
33. Ludwig, A., Zong, X., Jeglitsch, M., Hofmann, F. &Biel, M. A family of hyperpolarization-activated mammalian cation channels. Nature 393, 587-591 (1998).
34. Santoro, B. et al. Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain. Cell 93, 717-729 (1998).
35. Li, J., Zagotta, W. N. & Lester, H. A. Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation. Q. Rev. Biophys. 30, 177-193 (1997).
36. Tibbs, G. R., Goulding, E. H. & Siegelbaum, S. A. Allosteric activation and tuning of ligand efficacy in cyclic-nucleotide-gated channels. Nature 386, 612-615 (1997).
37. DiFrancesco, D. Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node. J. Physiol. (Lond.) 515, 367-376 (1999).
38. Bean, B. P. Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence. Nature 340, 153-156 (1989).
39. Steriade, M. in Generalized Epilepsy. Neurobiological Approaches (eds. Avoli, M. et al.) 161-180 (Birkhauser, Boston, 1990).
40. Neher, E. Correction for liquid junction potentials in patch clamp experiments. Methods Enzymol. 207, 123-131 (1992).