Tissue Dynamics Spectroscopy for Three-Dimensional Tissue-Based Drug Screening

Journal of Laboratory Automation

Volumn 16, Issue 6, 2011, Pages 431-442

  Nolte, David D ^a   An, Ran ^a   Turek, John ^b   Jeong, Kwan ^c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c Korea Military Academy   (South Korea)

Author keywords

Apoptosis and necrosis; Coherence gating; Digital holography; Drug response spectrograms; Dynamic light scattering; Endogenous; Hierarchical clustering; Intracellular motility; Label free; Motility contrast imaging; Multi parameter phenotypic profiling; Multicellular tumor spheroids; Optical coherence imaging; Speckle holography; Tissue dynamics spectroscopy

Indexed keywords

CONTRAST IMAGING; DIGITAL HOLOGRAPHY; DRUG RESPONSE; ENDOGENOUS; HIER-ARCHICAL CLUSTERING; INTRACELLULAR MOTILITY; LABEL FREE; MULTICELLULAR TUMOR SPHEROIDS; MULTIPARAMETERS; OPTICAL COHERENCE IMAGING;

CELL DEATH; COMPUTER GENERATED HOLOGRAPHY; DYNAMIC LIGHT SCATTERING; DYNAMICS; GROWTH KINETICS; SPECKLE; SPECTROGRAPHS; THREE DIMENSIONAL; TUMORS;

COHERENT SCATTERING;

COLCHICINE; CYCLOHEXIMIDE; CYTOCHALASIN; IODOACETIC ACID; NOCODAZOLE; PACLITAXEL; TUMOR NECROSIS FACTOR;

ARTICLE; AUTOMATIC SPEECH RECOGNITION; CELL MOTION; CLUSTER ANALYSIS; DRUG SCREENING; DYNAMIC LIGHT SCATTERING; FLUCTUATION SPECTROSCOPY; HIERARCHICAL CLUSTER ANALYSIS; IMAGING SYSTEM; LIGHT SCATTERING; MOTILITY CONTRAST IMAGING; NONHUMAN; RAT; SPECTROSCOPY; TISSUE DYNAMICS SPECTROSCOPY; TUMOR SPHEROID;

ANIMALS; BIOMARKERS, PHARMACOLOGICAL; DRUG EVALUATION, PRECLINICAL; FEASIBILITY STUDIES; HUMANS; NEOPLASMS; OSTEOGENESIS; RATS; SPECTRUM ANALYSIS; SPHEROIDS, CELLULAR;

EID: 82855165172     PISSN: 22110682     EISSN: 22110690     Source Type: Journal    
DOI: 10.1016/j.jala.2011.05.002     Document Type: Article

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