메뉴 건너뛰기




Volumn 124, Issue 5, 1998, Pages 972-979

Differentiation and proliferation of primary rat hepatocytes cultured as spheroids

Author keywords

CDK inhibitor; Differentiation; Hepatocyte; Proliferation; Spheroid

Indexed keywords

ALBUMIN; ANTISENSE OLIGONUCLEOTIDE; BINDING PROTEIN; CYCLIN DEPENDENT KINASE; EUDRAGIT; POLY DEXTRO LYSINE; POLYMER; PROTEIN KINASE INHIBITOR; PROTEIN P21; PROTEIN P27; SCATTER FACTOR; TRANSCRIPTION FACTOR;

EID: 0031759085     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022215     Document Type: Article
Times cited : (51)

References (46)
  • 2
    • 0021285134 scopus 로고
    • Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • Nakamura, T., Nawa, K., and Ichihara, A. (1984) Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem. Biophys. Res. Commun. 122, 1450-1459
    • (1984) Biochem. Biophys. Res. Commun. , vol.122 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 3
    • 0041531109 scopus 로고
    • Transforming growth factor a may be a physiological regulator of liver regeneration by means of an autocrine mechanism
    • Mead, J.E. and Fausto, N. (1989) Transforming growth factor a may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc. Natl. Acad. Sci. USA 86,1558-1562
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 1558-1562
    • Mead, J.E.1    Fausto, N.2
  • 5
    • 0023090714 scopus 로고
    • Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver
    • Bissell, D.M., Arenson, D.M., Maher, J.J., and Roll, F.J. (1987) Support of cultured hepatocytes by a laminin-rich gel. Evidence for a functionally significant subendothelial matrix in normal rat liver. J. Clin. Invest. 79, 801-812
    • (1987) J. Clin. Invest. , vol.79 , pp. 801-812
    • Bissell, D.M.1    Arenson, D.M.2    Maher, J.J.3    Roll, F.J.4
  • 6
    • 0024121578 scopus 로고
    • Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes
    • Ben-Ze'ev, A., Robinson, G.S., Bucher, N.L.R., and Farmer, S.R. (1988) Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc. Natl. Acad. Sci. USA 85, 2161-2165
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2161-2165
    • Ben-Ze'ev, A.1    Robinson, G.S.2    Bucher, N.L.R.3    Farmer, S.R.4
  • 7
    • 0022204028 scopus 로고
    • Spheroidal aggregate culture of rat liver cells: Histotypic reorganization, biomatrix deposition, and maintenance of functional activities
    • Landry, J., Bernier, D., Quellet, C., Goyette, R., and Marceau, N. (1985) Spheroidal aggregate culture of rat liver cells: histotypic reorganization, biomatrix deposition, and maintenance of functional activities. J. Cell Biol. 101, 914-923
    • (1985) J. Cell Biol. , vol.101 , pp. 914-923
    • Landry, J.1    Bernier, D.2    Quellet, C.3    Goyette, R.4    Marceau, N.5
  • 8
    • 0024366784 scopus 로고
    • Continued high albumin production by multicellular spheroids of adult rat hepatocytes formed in the presence of liver-derived proteoglycans
    • Koide, N., Shinji, T., Tanabe, T., Asano, K., Kawaguchi, M., Sakaguchi, K., Koide, Y., Mon, M., and Tsuji, T. (1989) Continued high albumin production by multicellular spheroids of adult rat hepatocytes formed in the presence of liver-derived proteoglycans. Biochem. Biophys. Res. Commun. 161, 385-391
    • (1989) Biochem. Biophys. Res. Commun. , vol.161 , pp. 385-391
    • Koide, N.1    Shinji, T.2    Tanabe, T.3    Asano, K.4    Kawaguchi, M.5    Sakaguchi, K.6    Koide, Y.7    Mon, M.8    Tsuji, T.9
  • 9
    • 0031777205 scopus 로고    scopus 로고
    • Efficient induction of hepatocyte spheroids in a suspension culture using a water-soluble synthetic polymer as an artificial matrix
    • Yamada, K., Kamihira, M., Hamamoto, R., and Iijima, S. (1998) Efficient induction of hepatocyte spheroids in a suspension culture using a water-soluble synthetic polymer as an artificial matrix. J. Biochem. 123, 1017-1023
    • (1998) J. Biochem. , vol.123 , pp. 1017-1023
    • Yamada, K.1    Kamihira, M.2    Hamamoto, R.3    Iijima, S.4
  • 10
    • 0023628342 scopus 로고
    • Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters
    • Courtois, G., Morgan, J.G., Campbell, L.A., Fourel, G., and Crabtree, G.R. (1987) Interaction of a liver-specific nuclear factor with the fibrinogen and alpha 1-antitrypsin promoters. Science 238, 688-692
    • (1987) Science , vol.238 , pp. 688-692
    • Courtois, G.1    Morgan, J.G.2    Campbell, L.A.3    Fourel, G.4    Crabtree, G.R.5
  • 11
    • 0023322681 scopus 로고
    • Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses
    • Johnson, P.F., Landschulz, W.H., Graves, B.J., and McKnight, S.L. (1987) Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes Dev. 1, 133-146
    • (1987) Genes Dev. , vol.1 , pp. 133-146
    • Johnson, P.F.1    Landschulz, W.H.2    Graves, B.J.3    McKnight, S.L.4
  • 12
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao, Z., Umek, R.M., and McKnight, S.L. (1991) Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5, 1538-1552
    • (1991) Genes Dev. , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.M.2    McKnight, S.L.3
  • 13
    • 0029128067 scopus 로고
    • Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells
    • Vallet, V., Antoine, B., Chafey, P., Vandewalle, A., and Kahn, A. (1995) Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells. Mol. Cell Biol. 15, 5453-5460
    • (1995) Mol. Cell Biol. , vol.15 , pp. 5453-5460
    • Vallet, V.1    Antoine, B.2    Chafey, P.3    Vandewalle, A.4    Kahn, A.5
  • 14
    • 0025690311 scopus 로고
    • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
    • Sladek, F.M., Zhong, W.M., Lai, E., and Darnell, J.E., Jr. (1990) Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes Dev. 4, 2353-2365
    • (1990) Genes Dev. , vol.4 , pp. 2353-2365
    • Sladek, F.M.1    Zhong, W.M.2    Lai, E.3    Darnell Jr., J.E.4
  • 15
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J.W., Adami, G.R., Wei, N., Keyomarsi, K., and Elledge, S.J. (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 19
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, P.O. (1976) Preparation of isolated rat liver cells. Methods Cell Biol. 13, 29-83
    • (1976) Methods Cell Biol. , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 21
    • 0021213870 scopus 로고
    • Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
    • Greenberg, M.E. and Ziff, E.B. (1984) Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature 311, 433-438
    • (1984) Nature , vol.311 , pp. 433-438
    • Greenberg, M.E.1    Ziff, E.B.2
  • 24
    • 0024788217 scopus 로고
    • Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins
    • Kinoshita, T., Tashiro, K., and Nakamura, T. (1989) Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins. Biochem. Biophys. Res. Commun. 165, 1229-1234
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 1229-1234
    • Kinoshita, T.1    Tashiro, K.2    Nakamura, T.3
  • 25
    • 0025734655 scopus 로고
    • Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET
    • Naldini, L., Vigna, E., Narsimhan, R.P., Gaudino, G., Zarneger, K., Michalopoulos, G.K., and Comoglio, P.M. (1991) Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. Oncogene 6, 501-504
    • (1991) Oncogene , vol.6 , pp. 501-504
    • Naldini, L.1    Vigna, E.2    Narsimhan, R.P.3    Gaudino, G.4    Zarneger, K.5    Michalopoulos, G.K.6    Comoglio, P.M.7
  • 26
    • 0027218744 scopus 로고
    • Internalization and degradation of hepatocyte growth factor in hepatocytes with down-regulation of the receptor/c-Met
    • Naka, D., Shimomura, T., Yoshiyama, Y., Sato, M., Sato, M., Ishii, T., and Hara, H. (1993) Internalization and degradation of hepatocyte growth factor in hepatocytes with down-regulation of the receptor/c-Met. FEBS Lett. 329, 147-152
    • (1993) FEBS Lett. , vol.329 , pp. 147-152
    • Naka, D.1    Shimomura, T.2    Yoshiyama, Y.3    Sato, M.4    Sato, M.5    Ishii, T.6    Hara, H.7
  • 27
    • 0027322529 scopus 로고
    • Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger
    • Graziani, A., Gramaglia, D., dalla Zonca, P., and Comoglio, P.M. (1993) Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger. J. Biol. Chem. 268, 9165-9168
    • (1993) J. Biol. Chem. , vol.268 , pp. 9165-9168
    • Graziani, A.1    Gramaglia, D.2    Dalla Zonca, P.3    Comoglio, P.M.4
  • 28
    • 0024725630 scopus 로고
    • CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells
    • Friedman, A.D., Landschulz, W.H., and McKnight, S.L. (1989) CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. Genes Dev. 3, 1314-1322
    • (1989) Genes Dev. , vol.3 , pp. 1314-1322
    • Friedman, A.D.1    Landschulz, W.H.2    McKnight, S.L.3
  • 29
    • 0030697292 scopus 로고    scopus 로고
    • Three-dimensional cell cultures: From molecular mechanisms to clinical applications
    • Mueller-Klieser, W. (1997) Three-dimensional cell cultures: from molecular mechanisms to clinical applications. Am. J. Physiol. 273, 1109-1123
    • (1997) Am. J. Physiol. , vol.273 , pp. 1109-1123
    • Mueller-Klieser, W.1
  • 30
    • 0027713285 scopus 로고
    • Evolution of the bioartificial liver: The need for randomized clinical trials
    • Nyberg, S.L., Peshwa, M.V., Payne, W.D., Hu, W.S., and Cerra, F.B. (1993) Evolution of the bioartificial liver: the need for randomized clinical trials. Am. J. Surg. 166, 512-521
    • (1993) Am. J. Surg. , vol.166 , pp. 512-521
    • Nyberg, S.L.1    Peshwa, M.V.2    Payne, W.D.3    Hu, W.S.4    Cerra, F.B.5
  • 31
    • 85045533823 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: Involvement of protein tyrosine kinase and protein kinase C
    • Adachi, T., Nakashima, S., Saji, S., Nakamura, T., and Nozawa, Y. (1996) Mitogen-activated protein kinase activation in hepatocyte growth factor-stimulated rat hepatocytes: involvement of protein tyrosine kinase and protein kinase C. Hepatology 23, 1244-1253
    • (1996) Hepatology , vol.23 , pp. 1244-1253
    • Adachi, T.1    Nakashima, S.2    Saji, S.3    Nakamura, T.4    Nozawa, Y.5
  • 33
    • 0027965262 scopus 로고
    • Compartmentalization of SHC, GRB2 and mSOS, and hyper-phosphorylation of Raf-1 by EGF but not insulin in liver parenchyma
    • Di Guglielmo, G.M., Baass, P.C., Ou, W.J., Posner, B.I., and Bergeron, J.J. (1994) Compartmentalization of SHC, GRB2 and mSOS, and hyper-phosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J. 13, 4269-4277
    • (1994) EMBO J. , vol.13 , pp. 4269-4277
    • Di Guglielmo, G.M.1    Baass, P.C.2    Ou, W.J.3    Posner, B.I.4    Bergeron, J.J.5
  • 34
    • 0030899808 scopus 로고    scopus 로고
    • Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap
    • van der Geer, P., Henkemeyer, M., Jacks, T., and Pawson, T. (1997) Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap. Mol. Cell Biol. 17, 1840-1847
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1840-1847
    • Van Der Geer, P.1    Henkemeyer, M.2    Jacks, T.3    Pawson, T.4
  • 36
    • 0026698006 scopus 로고
    • Stimulation of mitogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction
    • Pomerance, M., Schweighoffer, F., Tocque, B., and Pierre, M. (1992) Stimulation of mitogen-activated protein kinase by oncogenic Ras p21 in Xenopus oocytes. Requirement for Ras p21-GTPase-activating protein interaction. J. Biol. Chem. 267, 16155-16160
    • (1992) J. Biol. Chem. , vol.267 , pp. 16155-16160
    • Pomerance, M.1    Schweighoffer, F.2    Tocque, B.3    Pierre, M.4
  • 37
    • 0027323295 scopus 로고
    • Epidermal growth factor and isoproterenol stimulation of the Ras-guanine nucleotide exchange factor in proliferating rat parotid gland acinar cells
    • Wang, P.L., Nakagawa, Y., and Humphreys-Beher, M.G. (1993) Epidermal growth factor and isoproterenol stimulation of the Ras-guanine nucleotide exchange factor in proliferating rat parotid gland acinar cells. Biochem. Biophys. Res. Commun. 192, 860-866
    • (1993) Biochem. Biophys. Res. Commun. , vol.192 , pp. 860-866
    • Wang, P.L.1    Nakagawa, Y.2    Humphreys-Beher, M.G.3
  • 38
    • 0031045203 scopus 로고    scopus 로고
    • Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2
    • Besser, D., Bardelli, A., Didichenko, S., Thelen, M., Comoglio, P.M., Ponzetto, C., and Nagamine, Y. (1997) Regulation of the urokinase-type plasminogen activator gene by the oncogene Tpr-Met involves GRB2. Oncogene 14, 705-711
    • (1997) Oncogene , vol.14 , pp. 705-711
    • Besser, D.1    Bardelli, A.2    Didichenko, S.3    Thelen, M.4    Comoglio, P.M.5    Ponzetto, C.6    Nagamine, Y.7
  • 40
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Ning, Y., Venable, S.F., Pereira-Smith, O.M., and Smith, J.R. (1994) Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell Res. 211, 90-98
    • (1994) Exp. Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 41
    • 0030601941 scopus 로고    scopus 로고
    • Adhesion-dependent control of cyclin E/cdk2 activity and cell cycle progression in normal cells but not in Ha-ras transformed NRK cells
    • Carstens, C.P., Kramer, A., and Fahl, W.E. (1996) Adhesion-dependent control of cyclin E/cdk2 activity and cell cycle progression in normal cells but not in Ha-ras transformed NRK cells. Exp. Cell Res. 229, 86-92
    • (1996) Exp. Cell Res. , vol.229 , pp. 86-92
    • Carstens, C.P.1    Kramer, A.2    Fahl, W.E.3
  • 42
    • 0024295767 scopus 로고
    • The leucine zipper: A hypothetical structure common to a new class of DNa binding proteins
    • Landschulz, W.H., Johnson, P.F., and McKnight, S.L. (1988) The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science 240, 1759-1764
    • (1988) Science , vol.240 , pp. 1759-1764
    • Landschulz, W.H.1    Johnson, P.F.2    McKnight, S.L.3
  • 43
    • 0026031601 scopus 로고
    • CCAAT-enhancer binding protein: A component of a differentiation switch
    • Umek, R.M., Friedman, A.D., and McKnight, S.L. (1991) CCAAT-enhancer binding protein: a component of a differentiation switch. Science 251, 288-292
    • (1991) Science , vol.251 , pp. 288-292
    • Umek, R.M.1    Friedman, A.D.2    McKnight, S.L.3
  • 44
    • 0029962261 scopus 로고    scopus 로고
    • Liver-enriched transcription factors and hepatocyte differentiation
    • Cereghini, S. (1996) Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10, 267-282
    • (1996) FASEB J. , vol.10 , pp. 267-282
    • Cereghini, S.1
  • 45
    • 0029976068 scopus 로고    scopus 로고
    • CCAAT/enhancer-binding protein α (C/ EBPα) inhibits cell proliferation through the p21 (WAF-1/ CIP-1/SDI-1) protein
    • Timchenko, N.A., Wilde, M., Nakanishi, M., Smith, J.R., and Darlington, G.J. (1996) CCAAT/enhancer-binding protein α (C/ EBPα) inhibits cell proliferation through the p21 (WAF-1/ CIP-1/SDI-1) protein. Genes Dev. 10, 804-815
    • (1996) Genes Dev. , vol.10 , pp. 804-815
    • Timchenko, N.A.1    Wilde, M.2    Nakanishi, M.3    Smith, J.R.4    Darlington, G.J.5
  • 46
    • 0028129499 scopus 로고
    • Ectopic expression of the CCAAT/enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells
    • Freytag, S.O., Paielli, D.L., and Gilbert, J.D. (1994) Ectopic expression of the CCAAT/enhancer-binding protein a promotes the adipogenic program in a variety of mouse fibroblastic cells. Genes Dev. 8, 1654-1663
    • (1994) Genes Dev. , vol.8 , pp. 1654-1663
    • Freytag, S.O.1    Paielli, D.L.2    Gilbert, J.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.