c-Myb and GATA-3 cooperatively regulate IL-13 expression via conserved GATA-3 response element and recruit mixed lineage leukemia (MLL) for histone modification of the IL-13 locus

Journal of Immunology

Volumn 187, Issue 11, 2011, Pages 5974-5982

  Kozuka, Teruhiko ^a   Sugita, Mayumi ^a   Shetzline, Susan ^a   Gewirtz, Alan M ^a   Nakata, Yuji ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RA ANTIGEN; HISTONE H3; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; METHIONINE; PROTEIN C MYB; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR GATA 3;

ACETYLATION; ARTICLE; BINDING SITE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENE LOCUS; GENE SILENCING; HELPER CELL; HISTONE MODIFICATION; HUMAN; HUMAN CELL; MEMORY CELL; MUTATIONAL ANALYSIS; NORMAL HUMAN; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TH2 CELL;

CELL DIFFERENTIATION; CELL SEPARATION; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION; GENE EXPRESSION REGULATION; HISTONES; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-13; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROTO-ONCOGENE PROTEINS C-MYB; RESPONSE ELEMENTS; TH2 CELLS;

EID: 82755162143     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100550     Document Type: Article

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