Robustness can evolve gradually in complex regulatory gene networks with varying topology

PLoS Computational Biology

Volumn 3, Issue 2, 2007, Pages 0164-0173

  Ciliberti, Stefano ^a,b   Martin, Olivier C ^a,b,c   Wagner, Andreas ^d  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c INRA Institut National de la Recherche Agronomique   (France)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; GENE EXPRESSION;

BIOCHEMICAL PARAMETERS; CELLULARS; CIRCUIT BEHAVIORS; DRIVING CIRCUITS; GENE NETWORKS; HIGH ROBUSTNESS; NETWORK TOPOLOGY; ORGANIZATIONAL PRINCIPLES; REGULATORY GENES; VARYING TOPOLOGIES;

NETWORK TOPOLOGY;

PROTEIN; RNA; TRANSCRIPTION FACTOR;

ARTICLE; GENE EXPRESSION REGULATION; GENE MUTATION; MATHEMATICAL MODEL; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; REGULATOR GENE; RNA STRUCTURE; TRANSCRIPTION REGULATION; ADAPTATION; BIOLOGICAL MODEL; COMPUTER SIMULATION; GENETIC TRANSCRIPTION; GENETICS; MOLECULAR EVOLUTION; SIGNAL TRANSDUCTION;

ADAPTATION, PHYSIOLOGICAL; COMPUTER SIMULATION; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION; MODELS, GENETIC; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 33847268619     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0030015     Document Type: Article

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