-
1
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983. The Huntington's Disease Collaborative Research Group.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
3
-
-
33846225133
-
Huntington's disease
-
Walker F.O. Huntington's disease. Lancet 2007, 369:218-228.
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
4
-
-
72649103644
-
Irritability in pre-clinical Huntington's disease
-
Kloppel S., Stonnington C.M., Petrovic P., Mobbs D., Tuscher O., Craufurd D., et al. Irritability in pre-clinical Huntington's disease. Neuropsychologia 2009, 48:549-557.
-
(2009)
Neuropsychologia
, vol.48
, pp. 549-557
-
-
Kloppel, S.1
Stonnington, C.M.2
Petrovic, P.3
Mobbs, D.4
Tuscher, O.5
Craufurd, D.6
-
5
-
-
4344669917
-
Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation-a longitudinal follow-up study
-
Lemiere J., Decruyenaere M., Evers-Kiebooms G., Vandenbussche E., Dom R. Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation-a longitudinal follow-up study. J Neurol 2004, 251:935-942.
-
(2004)
J Neurol
, vol.251
, pp. 935-942
-
-
Lemiere, J.1
Decruyenaere, M.2
Evers-Kiebooms, G.3
Vandenbussche, E.4
Dom, R.5
-
6
-
-
0031814175
-
Evidence for specific cognitive deficits in preclinical Huntington's disease
-
Lawrence A.D., Hodges J.R., Rosser A.E., Kershaw A., ffrench-Constant C., Rubinsztein D.C., et al. Evidence for specific cognitive deficits in preclinical Huntington's disease. Brain 1998, 121(Pt 7):1329-1341.
-
(1998)
Brain
, vol.121
, Issue.PART 7
, pp. 1329-1341
-
-
Lawrence, A.D.1
Hodges, J.R.2
Rosser, A.E.3
Kershaw, A.4
ffrench-Constant, C.5
Rubinsztein, D.C.6
-
7
-
-
0035118624
-
Longitudinal evaluation of cognitive disorder in Huntington's disease
-
Snowden J., Craufurd D., Griffiths H., Thompson J., Neary D. Longitudinal evaluation of cognitive disorder in Huntington's disease. J Int Neuropsychol Soc 2001, 7:33-44.
-
(2001)
J Int Neuropsychol Soc
, vol.7
, pp. 33-44
-
-
Snowden, J.1
Craufurd, D.2
Griffiths, H.3
Thompson, J.4
Neary, D.5
-
8
-
-
1242338962
-
Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus
-
Ayalon L., Doron R., Weiner I., Joel D. Amelioration of behavioral deficits in a rat model of Huntington's disease by an excitotoxic lesion to the globus pallidus. Exp Neurol 2004, 186:46-58.
-
(2004)
Exp Neurol
, vol.186
, pp. 46-58
-
-
Ayalon, L.1
Doron, R.2
Weiner, I.3
Joel, D.4
-
9
-
-
2342598416
-
Experimental therapeutics in transgenic mouse models of Huntington's disease
-
Beal M.F., Ferrante R.J. Experimental therapeutics in transgenic mouse models of Huntington's disease. Nat Rev Neurosci 2004, 5:373-384.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 373-384
-
-
Beal, M.F.1
Ferrante, R.J.2
-
11
-
-
0023633397
-
Amino acid neurotransmitter abnormalities in Huntington's disease and the quinolinic acid animal model of Huntington's disease
-
Ellison D.W., Beal M.F., Mazurek M.F., Malloy J.R., Bird E.D., Martin J.B. Amino acid neurotransmitter abnormalities in Huntington's disease and the quinolinic acid animal model of Huntington's disease. Brain 1987, 110(Pt 6):1657-1673.
-
(1987)
Brain
, vol.110
, Issue.PART 6
, pp. 1657-1673
-
-
Ellison, D.W.1
Beal, M.F.2
Mazurek, M.F.3
Malloy, J.R.4
Bird, E.D.5
Martin, J.B.6
-
12
-
-
0033982887
-
Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse
-
Tabrizi S.J., Workman J., Hart P.E., Mangiarini L., Mahal A., Bates G., et al. Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse. Ann Neurol 2000, 47:80-86.
-
(2000)
Ann Neurol
, vol.47
, pp. 80-86
-
-
Tabrizi, S.J.1
Workman, J.2
Hart, P.E.3
Mangiarini, L.4
Mahal, A.5
Bates, G.6
-
13
-
-
10544222019
-
Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype
-
Hodgson J.G., Smith D.J., McCutcheon K., Koide H.B., Nishiyama K., Dinulos M.B., et al. Human huntingtin derived from YAC transgenes compensates for loss of murine huntingtin by rescue of the embryonic lethal phenotype. Hum Mol Genet 1996, 5:1875-1885.
-
(1996)
Hum Mol Genet
, vol.5
, pp. 1875-1885
-
-
Hodgson, J.G.1
Smith, D.J.2
McCutcheon, K.3
Koide, H.B.4
Nishiyama, K.5
Dinulos, M.B.6
-
14
-
-
0037444426
-
Transgenic rat model of Huntington's disease
-
von Horsten S., Schmitt I., Nguyen H.P., Holzmann C., Schmidt T., Walther T., et al. Transgenic rat model of Huntington's disease. Hum Mol Genet 2003, 12:617-624.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 617-624
-
-
von Horsten, S.1
Schmitt, I.2
Nguyen, H.P.3
Holzmann, C.4
Schmidt, T.5
Walther, T.6
-
15
-
-
33744781583
-
Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats
-
Kantor O., Temel Y., Holzmann C., Raber K., Nguyen H.P., Cao C., et al. Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats. Neurobiol Dis 2006, 22:538-547.
-
(2006)
Neurobiol Dis
, vol.22
, pp. 538-547
-
-
Kantor, O.1
Temel, Y.2
Holzmann, C.3
Raber, K.4
Nguyen, H.P.5
Cao, C.6
-
16
-
-
33750210519
-
Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease
-
Nguyen H.P., Kobbe P., Rahne H., Worpel T., Jager B., Stephan M., et al. Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Hum Mol Genet 2006, 15:3177-3194.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 3177-3194
-
-
Nguyen, H.P.1
Kobbe, P.2
Rahne, H.3
Worpel, T.4
Jager, B.5
Stephan, M.6
-
17
-
-
33847317865
-
Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease
-
Petrasch-Parwez E., Nguyen H.P., Lobbecke-Schumacher M., Habbes H.W., Wieczorek S., Riess O., et al. Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease. J Comp Neurol 2007, 501:716-730.
-
(2007)
J Comp Neurol
, vol.501
, pp. 716-730
-
-
Petrasch-Parwez, E.1
Nguyen, H.P.2
Lobbecke-Schumacher, M.3
Habbes, H.W.4
Wieczorek, S.5
Riess, O.6
-
18
-
-
78651230354
-
Altered emotional and motivational processing in the transgenic rat model for Huntington's disease
-
Faure A., Hohn S., Von Horsten S., Delatour B., Raber K., Le Blanc P., et al. Altered emotional and motivational processing in the transgenic rat model for Huntington's disease. Neurobiol Learn Mem 2011, 95:92-101.
-
(2011)
Neurobiol Learn Mem
, vol.95
, pp. 92-101
-
-
Faure, A.1
Hohn, S.2
Von Horsten, S.3
Delatour, B.4
Raber, K.5
Le Blanc, P.6
-
19
-
-
69249218896
-
Progressive imbalance in the interaction between spatial and procedural memory systems in the R6/2 mouse model of Huntington's disease
-
Ciamei A., Morton A.J. Progressive imbalance in the interaction between spatial and procedural memory systems in the R6/2 mouse model of Huntington's disease. Neurobiol Learn Mem 2009, 92:417-428.
-
(2009)
Neurobiol Learn Mem
, vol.92
, pp. 417-428
-
-
Ciamei, A.1
Morton, A.J.2
-
20
-
-
61349116180
-
The role of the basal ganglia in learning and memory: neuropsychological studies
-
Grahn J.A., Parkinson J.A., Owen A.M. The role of the basal ganglia in learning and memory: neuropsychological studies. Behav Brain Res 2009, 199:53-60.
-
(2009)
Behav Brain Res
, vol.199
, pp. 53-60
-
-
Grahn, J.A.1
Parkinson, J.A.2
Owen, A.M.3
-
21
-
-
79955767704
-
Striatum-hippocampus balance: from physiological behavior to interneuronal pathology
-
Ghiglieri V., Sgobio C., Costa C., Picconi B., Calabresi P. Striatum-hippocampus balance: from physiological behavior to interneuronal pathology. Prog Neurobiol 2011, 94:102-114.
-
(2011)
Prog Neurobiol
, vol.94
, pp. 102-114
-
-
Ghiglieri, V.1
Sgobio, C.2
Costa, C.3
Picconi, B.4
Calabresi, P.5
-
22
-
-
0033934298
-
Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits
-
Lawrence A.D., Watkins L.H., Sahakian B.J., Hodges J.R., Robbins T.W. Visual object and visuospatial cognition in Huntington's disease: implications for information processing in corticostriatal circuits. Brain 2000, 123(Pt 7):1349-1364.
-
(2000)
Brain
, vol.123
, Issue.PART 7
, pp. 1349-1364
-
-
Lawrence, A.D.1
Watkins, L.H.2
Sahakian, B.J.3
Hodges, J.R.4
Robbins, T.W.5
-
23
-
-
0033818248
-
Identifying cortical inputs to the rat hippocampus that subserve allocentric spatial processes: a simple problem with a complex answer
-
Aggleton J.P., Vann S.D., Oswald C.J., Good M. Identifying cortical inputs to the rat hippocampus that subserve allocentric spatial processes: a simple problem with a complex answer. Hippocampus 2000, 10:466-474.
-
(2000)
Hippocampus
, vol.10
, pp. 466-474
-
-
Aggleton, J.P.1
Vann, S.D.2
Oswald, C.J.3
Good, M.4
-
24
-
-
35548984920
-
Perirhinal cortex damage and anterograde object-recognition in rats after long retention intervals
-
Mumby D.G., Piterkin P., Lecluse V., Lehmann H. Perirhinal cortex damage and anterograde object-recognition in rats after long retention intervals. Behav Brain Res 2007, 185:82-87.
-
(2007)
Behav Brain Res
, vol.185
, pp. 82-87
-
-
Mumby, D.G.1
Piterkin, P.2
Lecluse, V.3
Lehmann, H.4
-
26
-
-
58149522902
-
Functional difference between rat perirhinal cortex and hippocampus in object and place discrimination tasks
-
Abe H., Ishida Y., Nonaka H., Iwasaki T. Functional difference between rat perirhinal cortex and hippocampus in object and place discrimination tasks. Behav Brain Res 2009, 197:388-397.
-
(2009)
Behav Brain Res
, vol.197
, pp. 388-397
-
-
Abe, H.1
Ishida, Y.2
Nonaka, H.3
Iwasaki, T.4
-
27
-
-
0030688947
-
Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast
-
Prickaerts J., Steinbusch H.W., Smits J.F., de Vente J. Possible role of nitric oxide-cyclic GMP pathway in object recognition memory: effects of 7-nitroindazole and zaprinast. Eur J Pharmacol 1997, 337:125-136.
-
(1997)
Eur J Pharmacol
, vol.337
, pp. 125-136
-
-
Prickaerts, J.1
Steinbusch, H.W.2
Smits, J.F.3
de Vente, J.4
-
28
-
-
0023691166
-
A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data
-
Ennaceur A., Delacour J. A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data. Behav Brain Res 1988, 31:47-59.
-
(1988)
Behav Brain Res
, vol.31
, pp. 47-59
-
-
Ennaceur, A.1
Delacour, J.2
-
29
-
-
4243053608
-
Phosphodiesterase type 5 inhibition improves early memory consolidation of object information
-
Prickaerts J., Sik A., van Staveren W.C., Koopmans G., Steinbusch H.W., van der Staay F.J., et al. Phosphodiesterase type 5 inhibition improves early memory consolidation of object information. Neurochem Int 2004, 45:915-928.
-
(2004)
Neurochem Int
, vol.45
, pp. 915-928
-
-
Prickaerts, J.1
Sik, A.2
van Staveren, W.C.3
Koopmans, G.4
Steinbusch, H.W.5
van der Staay, F.J.6
-
30
-
-
0036292339
-
A role for olfaction in object recognition by normal and hippocampal-damaged rats
-
Astur R.S., Klein R.L., Mumby D.G., Protz D.K., Sutherland R.J., Martin G.M. A role for olfaction in object recognition by normal and hippocampal-damaged rats. Neurobiol Learn Mem 2002, 78:186-191.
-
(2002)
Neurobiol Learn Mem
, vol.78
, pp. 186-191
-
-
Astur, R.S.1
Klein, R.L.2
Mumby, D.G.3
Protz, D.K.4
Sutherland, R.J.5
Martin, G.M.6
-
31
-
-
67449124349
-
Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats
-
Rutten K., Van Donkelaar E.L., Ferrington L., Blokland A., Bollen E., Steinbusch H.W., et al. Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats. Neuropsychopharmacology 2009, 34:1914-1925.
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1914-1925
-
-
Rutten, K.1
Van Donkelaar, E.L.2
Ferrington, L.3
Blokland, A.4
Bollen, E.5
Steinbusch, H.W.6
-
32
-
-
9144259577
-
Profile of cognitive progression in early Huntington's disease
-
Ho A.K., Sahakian B.J., Brown R.G., Barker R.A., Hodges J.R., Ane M.N., et al. Profile of cognitive progression in early Huntington's disease. Neurology 2003, 61:1702-1706.
-
(2003)
Neurology
, vol.61
, pp. 1702-1706
-
-
Ho, A.K.1
Sahakian, B.J.2
Brown, R.G.3
Barker, R.A.4
Hodges, J.R.5
Ane, M.N.6
-
33
-
-
33745231157
-
Episodic memory impairment in Huntington's disease: a meta-analysis
-
Montoya A., Pelletier M., Menear M., Duplessis E., Richer F., Lepage M. Episodic memory impairment in Huntington's disease: a meta-analysis. Neuropsychologia 2006, 44:1984-1994.
-
(2006)
Neuropsychologia
, vol.44
, pp. 1984-1994
-
-
Montoya, A.1
Pelletier, M.2
Menear, M.3
Duplessis, E.4
Richer, F.5
Lepage, M.6
-
34
-
-
17644368893
-
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease
-
Van Raamsdonk J.M., Pearson J., Slow E.J., Hossain S.M., Leavitt B.R., Hayden M.R. Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease. J Neurosci 2005, 25:4169-4180.
-
(2005)
J Neurosci
, vol.25
, pp. 4169-4180
-
-
Van Raamsdonk, J.M.1
Pearson, J.2
Slow, E.J.3
Hossain, S.M.4
Leavitt, B.R.5
Hayden, M.R.6
-
35
-
-
0034847765
-
Juvenile onset Huntington's disease-clinical and research perspectives
-
Nance M.A., Myers R.H. Juvenile onset Huntington's disease-clinical and research perspectives. Ment Retard Dev Disabil Res Rev 2001, 7:153-157.
-
(2001)
Ment Retard Dev Disabil Res Rev
, vol.7
, pp. 153-157
-
-
Nance, M.A.1
Myers, R.H.2
-
36
-
-
33646524704
-
Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel
-
Cao C., Temel Y., Blokland A., Ozen H., Steinbusch H.W., Vlamings R., et al. Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel. Behav Brain Res 2006, 170:257-261.
-
(2006)
Behav Brain Res
, vol.170
, pp. 257-261
-
-
Cao, C.1
Temel, Y.2
Blokland, A.3
Ozen, H.4
Steinbusch, H.W.5
Vlamings, R.6
-
37
-
-
4744370526
-
Fine-structural analysis and connexin expression in the retina of a transgenic model of Huntington's disease
-
Petrasch-Parwez E., Habbes H.W., Weickert S., Lobbecke-Schumacher M., Striedinger K., Wieczorek S., et al. Fine-structural analysis and connexin expression in the retina of a transgenic model of Huntington's disease. J Comp Neurol 2004, 479:181-197.
-
(2004)
J Comp Neurol
, vol.479
, pp. 181-197
-
-
Petrasch-Parwez, E.1
Habbes, H.W.2
Weickert, S.3
Lobbecke-Schumacher, M.4
Striedinger, K.5
Wieczorek, S.6
-
38
-
-
33644531897
-
Brain imaging and cognitive dysfunctions in Huntington's disease
-
Montoya A., Price B.H., Menear M., Lepage M. Brain imaging and cognitive dysfunctions in Huntington's disease. J Psychiatry Neurosci 2006, 31:21-29.
-
(2006)
J Psychiatry Neurosci
, vol.31
, pp. 21-29
-
-
Montoya, A.1
Price, B.H.2
Menear, M.3
Lepage, M.4
-
39
-
-
60349130539
-
Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression
-
Giralt A., Rodrigo T., Martin E.D., Gonzalez J.R., Mila M., Cena V., et al. Brain-derived neurotrophic factor modulates the severity of cognitive alterations induced by mutant huntingtin: involvement of phospholipaseCgamma activity and glutamate receptor expression. Neuroscience 2009, 158:1234-1250.
-
(2009)
Neuroscience
, vol.158
, pp. 1234-1250
-
-
Giralt, A.1
Rodrigo, T.2
Martin, E.D.3
Gonzalez, J.R.4
Mila, M.5
Cena, V.6
-
40
-
-
0034234519
-
Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation
-
Murphy K.P., Carter R.J., Lione L.A., Mangiarini L., Mahal A., Bates G.P., et al. Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation. J Neurosci 2000, 20:5115-5123.
-
(2000)
J Neurosci
, vol.20
, pp. 5115-5123
-
-
Murphy, K.P.1
Carter, R.J.2
Lione, L.A.3
Mangiarini, L.4
Mahal, A.5
Bates, G.P.6
-
41
-
-
37449011119
-
Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load
-
Milnerwood A.J., Raymond L.A. Corticostriatal synaptic function in mouse models of Huntington's disease: early effects of huntingtin repeat length and protein load. J Physiol 2007, 585:817-831.
-
(2007)
J Physiol
, vol.585
, pp. 817-831
-
-
Milnerwood, A.J.1
Raymond, L.A.2
-
42
-
-
63849151219
-
Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice
-
Simmons D.A., Rex C.S., Palmer L., Pandyarajan V., Fedulov V., Gall C.M., et al. Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice. Proc Natl Acad Sci USA 2009, 106:4906-4911.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 4906-4911
-
-
Simmons, D.A.1
Rex, C.S.2
Palmer, L.3
Pandyarajan, V.4
Fedulov, V.5
Gall, C.M.6
|