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Volumn 21, Issue 3, 1997, Pages 289-293

3-Nitropropionic acid animal model and Huntington's disease

Author keywords

3 Nitropropionic acid; Huntington's disease; Locomotor activity; Mitochondrial toxin; Neurodegeneration; Striatum

Indexed keywords

3 NITROPROPIONIC ACID; 3,4 DIHYDROXYPHENYLACETIC ACID; 4 AMINOBUTYRIC ACID; ADENOSINE TRIPHOSPHATE; CHOLINE ACETYLTRANSFERASE; DOPAMINE; EXCITOTOXIN; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; HOMOVANILLIC ACID; IBOTENIC ACID; KAINIC ACID; LACTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPEPTIDE Y; QUINOLINIC ACID; SOMATOSTATIN; SUBSTANCE P;

EID: 0030999657     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(96)00027-9     Document Type: Article
Times cited : (155)

References (33)
  • 1
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypothesis
    • Albin, R. L.; Greenamyre, J. T., Alternative excitotoxic hypothesis. Neurol. 42:733-738; 1992.
    • (1992) Neurol. , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 2
    • 0028793257 scopus 로고
    • Glutamate induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
    • Ankarcrona, M.; Dypbukt, J. M.; Bonfoco, E.; Zhivotovsky, B.; Orrenius, S.; Lipton, S. A.; Nicotera, P., Glutamate induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:961-973; 1995.
    • (1995) Neuron. , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 3
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
    • Beal, M. F., Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann. Neurol. 31:119-130; 1992.
    • (1992) Ann. Neurol. , vol.31 , pp. 119-130
    • Beal, M.F.1
  • 6
    • 0028862452 scopus 로고
    • Behavioral pathology induced by repeated systemic injections of 3-nitropropionic acid mimics the motoric symptoms of Huntington's disease
    • Borlongan, C. V.; Koutouzis, T. K.; Cahill, D. W.; Freeman, T. B.; Sanberg, P. R., Behavioral pathology induced by repeated systemic injections of 3-nitropropionic acid mimics the motoric symptoms of Huntington's disease. Brain Res. 697:254-257; 1995.
    • (1995) Brain Res. , vol.697 , pp. 254-257
    • Borlongan, C.V.1    Koutouzis, T.K.2    Cahill, D.W.3    Freeman, T.B.4    Sanberg, P.R.5
  • 7
    • 0027406823 scopus 로고
    • Age dependence of striatal neuronal death caused by mitochondrial dysfunction
    • Bossi, S. R.; Simpson, J. R.; Isacson, O., Age dependence of striatal neuronal death caused by mitochondrial dysfunction. Neuroreport. 4:73-76; 1993.
    • (1993) Neuroreport. , vol.4 , pp. 73-76
    • Bossi, S.R.1    Simpson, J.R.2    Isacson, O.3
  • 11
    • 0001670657 scopus 로고
    • Huntington's chorea, historical, clinical and laboratory synopsis
    • Bruyn, G. W., Huntington's chorea, historical, clinical and laboratory synopsis. Handbook Clin. Neurol. 6:298-378; 1968.
    • (1968) Handbook Clin. Neurol. , vol.6 , pp. 298-378
    • Bruyn, G.W.1
  • 12
    • 0024412962 scopus 로고
    • Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: Role of the voltage-dependent magnesium block
    • Cox, J. A.; Lysko, P. G.; Henneberry, R. C., Excitatory amino acid neurotoxicity at the N-methyl-D-aspartate receptor in cultured neurons: role of the voltage-dependent magnesium block. Brain Res. 499:267-272; 1989.
    • (1989) Brain Res. , vol.499 , pp. 267-272
    • Cox, J.A.1    Lysko, P.G.2    Henneberry, R.C.3
  • 13
    • 0025252429 scopus 로고
    • Nigral dopamine type-1 are reduced in Huntington's disease: A postmortem autoradiographic study using the [3H] SCH23390 and correlation with [3H] forskolin binding
    • Filloux, F.; Wagster, M. V.; Folstein, S.; Price, D. L.; Hedreen, J. C.; Dawson, T. M.; Wamsley, J. K., Nigral dopamine type-1 are reduced in Huntington's disease: a postmortem autoradiographic study using the [3H] SCH23390 and correlation with [3H] forskolin binding. Exp. Neurol. 110:219-227; 1990.
    • (1990) Exp. Neurol. , vol.110 , pp. 219-227
    • Filloux, F.1    Wagster, M.V.2    Folstein, S.3    Price, D.L.4    Hedreen, J.C.5    Dawson, T.M.6    Wamsley, J.K.7
  • 14
    • 0020465435 scopus 로고
    • Basal ganglia degeneration, myelin alterations, and enzyme inhibition in mice induced by the plant toxin 3-nitropropionic acid
    • Gould, D. H.; Gustine, D. L., Basal ganglia degeneration, myelin alterations, and enzyme inhibition in mice induced by the plant toxin 3-nitropropionic acid. Neuropathol. Appl. Neurobiol. 8:377-393; 1982.
    • (1982) Neuropathol. Appl. Neurobiol. , vol.8 , pp. 377-393
    • Gould, D.H.1    Gustine, D.L.2
  • 16
    • 0023118066 scopus 로고
    • Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: A type of hypoxic (energy deficient) brain damage
    • Hamilton, B. F.; Gould, D. H., Nature and distribution of brain lesions in rats intoxicated with 3-nitropropionic acid: a type of hypoxic (energy deficient) brain damage. Acta Neuropathol. 72:286-297; 1987.
    • (1987) Acta Neuropathol. , vol.72 , pp. 286-297
    • Hamilton, B.F.1    Gould, D.H.2
  • 17
    • 0025279038 scopus 로고
    • A primate model of huntington's disease: Behavioural and anatomical studies of unilateral excitotoxic lesions of the caudate-putaman in the baboon
    • Hantraye, P.; Riche, D.; Maziere, M.; Isacson, O., A primate model of Huntington's disease: behavioural and anatomical studies of unilateral excitotoxic lesions of the caudate-putaman in the baboon. Exp. Neurol. 108:91-104; 1990.
    • (1990) Exp. Neurol. , vol.108 , pp. 91-104
    • Hantraye, P.1    Riche, D.2    Maziere, M.3    Isacson, O.4
  • 18
    • 0022323862 scopus 로고
    • Neural grafting in the rat model of Huntington's disease: Progressive neuro-chemical changes after neostriatal ibotenate lesions and tissue grafting
    • Isacson, O.; Brundin, P.; Gage, F. H.; Bjorkland, A., Neural grafting in the rat model of Huntington's disease: progressive neuro-chemical changes after neostriatal ibotenate lesions and tissue grafting. Neurosci. 16:799-817; 1985.
    • (1985) Neurosci. , vol.16 , pp. 799-817
    • Isacson, O.1    Brundin, P.2    Gage, F.H.3    Bjorkland, A.4
  • 19
    • 0000992532 scopus 로고
    • Localized proton-NMR spectroscopy in patients with Huntinton's disease (HD) demonstrates abnormal lactate levels in occipital cortex: Evidence for compromised metabolism in HD
    • Koroshetz, W. J.; Jenkins, B. G.; Beal, M. F.; Rosen, B. R., Localized proton-NMR spectroscopy in patients with Huntinton's disease (HD) demonstrates abnormal lactate levels in occipital cortex: evidence for compromised metabolism in HD. Neurology 42:319; 1992.
    • (1992) Neurology , vol.42 , pp. 319
    • Koroshetz, W.J.1    Jenkins, B.G.2    Beal, M.F.3    Rosen, B.R.4
  • 23
    • 0026357457 scopus 로고
    • 3-nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin
    • Ludolph, A. C.; He, F.; Spencer, P. F.; Hammerstad, J.; Sabri, M., 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Can. J. Neurol. Sci. 18:492-498; 1991.
    • (1991) Can. J. Neurol. Sci. , vol.18 , pp. 492-498
    • Ludolph, A.C.1    He, F.2    Spencer, P.F.3    Hammerstad, J.4    Sabri, M.5
  • 24
    • 0022876328 scopus 로고
    • Huntington's disease: Pathenogenesis and management
    • Martin, J. B.; Gusella, J. F., Huntington's disease: pathenogenesis and management. N. Engl. J. Med. 315:1267-1276; 1986.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1267-1276
    • Martin, J.B.1    Gusella, J.F.2
  • 25
    • 0015294581 scopus 로고
    • Choreoathetosis and striopallidonigral necrosis due to sodium azide
    • Mettler, F. A., Choreoathetosis and striopallidonigral necrosis due to sodium azide. Exp. Neurol. 34:291-308; 1972.
    • (1972) Exp. Neurol. , vol.34 , pp. 291-308
    • Mettler, F.A.1
  • 26
    • 0028942180 scopus 로고
    • Chronically administered 3-nitropropionic acid induces striatal lesions attributed to dysfunction of the blood-brain barrier
    • Nishino, H.; Shimano, Y.; Kumazaki, M.; Sakurai, T., Chronically administered 3-nitropropionic acid induces striatal lesions attributed to dysfunction of the blood-brain barrier. Neurosci. Lett. 186:161-164; 1995.
    • (1995) Neurosci. Lett. , vol.186 , pp. 161-164
    • Nishino, H.1    Shimano, Y.2    Kumazaki, M.3    Sakurai, T.4
  • 27
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energies are reduced
    • Novelli, A.; Reilly, L. A.; Lysko, P. G.; Henneberry, R. C., Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energies are reduced. Brain Res. 451:205-212; 1988.
    • (1988) Brain Res. , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, L.A.2    Lysko, P.G.3    Henneberry, R.C.4
  • 29
    • 0029450117 scopus 로고
    • Chronically administered 3-nitropropionic acid produces selective lesions in the striatum and reduces muscle tonus
    • Shimano, Y.; Kumazaki, M.; Sakurai, T.; Hida, H.; Fujimoto, I.; Fukuda, A.; Nishino, H., Chronically administered 3-nitropropionic acid produces selective lesions in the striatum and reduces muscle tonus. Obesity Res. 3:779-784; 1995.
    • (1995) Obesity Res. , vol.3 , pp. 779-784
    • Shimano, Y.1    Kumazaki, M.2    Sakurai, T.3    Hida, H.4    Fujimoto, I.5    Fukuda, A.6    Nishino, H.7
  • 30
    • 0343165135 scopus 로고
    • Huntington's disease
    • Asbury, A.; McKhann, G. M.; McDonald, I., eds. Philadelphia: Ardmore Medical Books (W. B. Saunders)
    • Shoulson, I. Huntington's Disease. In: Asbury, A.; McKhann, G. M.; McDonald, I., eds. The disease of the nervous system. Philadelphia: Ardmore Medical Books (W. B. Saunders); 1986:1258-1267.;
    • (1986) The Disease of the Nervous System , pp. 1258-1267
    • Shoulson, I.1
  • 31
    • 0021325983 scopus 로고
    • Bicaudate diameter - The most specific and simplified CT parameter in the diagnosis of Huntington's disease
    • Stober, T.; Wussow, W.; Schimrigk, K., Bicaudate diameter - the most specific and simplified CT parameter in the diagnosis of Huntington's disease. Neuroradiol. 26:25-28; 1984.
    • (1984) Neuroradiol. , vol.26 , pp. 25-28
    • Stober, T.1    Wussow, W.2    Schimrigk, K.3
  • 32
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Collaborative Group, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:971-983; 1993.
    • (1993) Cell , vol.72 , pp. 971-983
  • 33
    • 0027525354 scopus 로고
    • Excitotoxic neuronal damage and neuropsychiatric disorders
    • Zorumski, C. F.; Olney, J. W., Excitotoxic neuronal damage and neuropsychiatric disorders. J. Pharm. Ther. 59:145-162; 1993.
    • (1993) J. Pharm. Ther. , vol.59 , pp. 145-162
    • Zorumski, C.F.1    Olney, J.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.