Simvastatin pretreatment prevents ambient particle-induced lung injury in mice

Inhalation Toxicology

Volumn 23, Issue 14, 2011, Pages 889-896

  Ferraro, Sebastian A ^a,b   Yakisich, Juan S ^c   Gallo, Francisco T ^a   Tasat, Deborah R ^a,d  

^a National University of General San Martn   (Argentina)

^b Buenos Aires Committee for Scientific Research   (Argentina)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Ambient particle; Inflammation; Lung; Oxidative stress; ROFA; Simvastatin

Indexed keywords

BIOLOGICAL MARKER; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; SIMVASTATIN; SUPEROXIDE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; AIR PARTICLE CONTROL; AIR POLLUTANT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CELL COUNT; CELL POPULATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL TEMPERATURE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLY ASH; LUNG HOMOGENATE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RESIDUAL OIL FLY ASH; SCANNING ELECTRON MICROSCOPY; URBAN AREA;

AIR POLLUTANTS; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; COAL ASH; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERLEUKIN-6; LUNG INJURY; MALE; MICE; MICE, INBRED BALB C; PARTICULATE MATTER; PNEUMONIA; PROTECTIVE AGENTS; SIMVASTATIN; SUPEROXIDE DISMUTASE; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 82655166399     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2011.623195     Document Type: Article

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