-
1
-
-
70350129236
-
Protective mechanisms of activated protein C in severe inflammatory disorders
-
Neyrinck, A.P.; Liu, K.D.; Howard, J.P.; Matthay, M.A. Protective mechanisms of activated protein C in severe inflammatory disorders. Br. J. Pharmacol., 2009, 158(4), 1034-1047.
-
(2009)
Br. J. Pharmacol
, vol.158
, Issue.4
, pp. 1034-1047
-
-
Neyrinck, A.P.1
Liu, K.D.2
Howard, J.P.3
Matthay, M.A.4
-
2
-
-
16644395324
-
Cholesterol-independent effects of statins and new therapeutic targets: Ischemic stroke and dementia
-
Miida, T.; Hirayama, S.; Nakamura, Y. Cholesterol-independent effects of statins and new therapeutic targets: ischemic stroke and dementia. J. Atheroscler Thromb., 2004, 11(5), 253-264.
-
(2004)
J. Atheroscler Thromb
, vol.11
, Issue.5
, pp. 253-264
-
-
Miida, T.1
Hirayama, S.2
Nakamura, Y.3
-
3
-
-
29444438428
-
Clinical implications for statin pleiotropy
-
Liao, J.K. Clinical implications for statin pleiotropy. Curr. Opin. Lipidol., 2005, 16(6), 624-629.
-
(2005)
Curr. Opin. Lipidol
, vol.16
, Issue.6
, pp. 624-629
-
-
Liao, J.K.1
-
4
-
-
45749148199
-
Simvastatin inhibits Staphylococcus aureus host cell invasion through modulation of isoprenoid intermediates
-
Horn, M.P.; Knecht, S.M.; Rushing, F.L.; Birdsong, J.; Siddall, C.P.; Johnson, C.M.; Abraham, T.N.; Brown, A.; Volk, C.B.; Gammon, K.; Bishop, D.L.; McKillip, J.L.; McDowell, S.A. Simvastatin inhibits Staphylococcus aureus host cell invasion through modulation of isoprenoid intermediates. J. Pharmacol. Exp. Ther., 2008, 326(1), 135-143.
-
(2008)
J. Pharmacol. Exp. Ther
, vol.326
, Issue.1
, pp. 135-143
-
-
Horn, M.P.1
Knecht, S.M.2
Rushing, F.L.3
Birdsong, J.4
Siddall, C.P.5
Johnson, C.M.6
Abraham, T.N.7
Brown, A.8
Volk, C.B.9
Gammon, K.10
Bishop, D.L.11
McKillip, J.L.12
McDowell, S.A.13
-
5
-
-
0032729649
-
Bacterial speciesand strain-dependent induction of tissue factor in human vascular endothelial cells
-
Veltrop, M.H.; Beekhuizen, H.; Thompson, J. Bacterial speciesand strain-dependent induction of tissue factor in human vascular endothelial cells. Infect. Immun., 1999, 67(11), 6130-6138.
-
(1999)
Infect. Immun
, vol.67
, Issue.11
, pp. 6130-6138
-
-
Veltrop, M.H.1
Beekhuizen, H.2
Thompson, J.3
-
6
-
-
62549115317
-
Contribution of (sub)domains of Staphylococcus aureus fibronectin-binding protein to the proinflammatory and procoagulant response of human vascular endothelial cells
-
Heying, R.; van de Gevel, J.; Que, Y.A.; Piroth, L.; Moreillon, P.; Beekhuizen, H. Contribution of (sub)domains of Staphylococcus aureus fibronectin-binding protein to the proinflammatory and procoagulant response of human vascular endothelial cells. Thromb. Haemost., 2009, 101(3), 495-504.
-
(2009)
Thromb. Haemost
, vol.101
, Issue.3
, pp. 495-504
-
-
Heying, R.1
van de Gevel, J.2
Que, Y.A.3
Piroth, L.4
Moreillon, P.5
Beekhuizen, H.6
-
7
-
-
0035887840
-
The effect of statins on mortality in patients with bacteremia
-
Liappis, A.P.; Kan, V.L.; Rochester, C.G.; Simon, G.L. The effect of statins on mortality in patients with bacteremia. Clin. Infect. Dis., 2001, 33(8), 1352-1357.
-
(2001)
Clin. Infect. Dis
, vol.33
, Issue.8
, pp. 1352-1357
-
-
Liappis, A.P.1
Kan, V.L.2
Rochester, C.G.3
Simon, G.L.4
-
8
-
-
4143083577
-
Prior statin therapy is associated with a decreased rate of severe sepsis
-
Almog, Y.; Shefer, A.; Novack, V.; Maimon, N.; Barski, L.; Eizinger, M.; Friger, M.; Zeller, L.; Danon, A. Prior statin therapy is associated with a decreased rate of severe sepsis. Circulation, 2004, 110(7), 880-885.
-
(2004)
Circulation
, vol.110
, Issue.7
, pp. 880-885
-
-
Almog, Y.1
Shefer, A.2
Novack, V.3
Maimon, N.4
Barski, L.5
Eizinger, M.6
Friger, M.7
Zeller, L.8
Danon, A.9
-
9
-
-
33646519915
-
Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects
-
Yasuda, H.; Yuen, P.S.; Hu, X.; Zhou, H.; Star, R.A. Simvastatin improves sepsis-induced mortality and acute kidney injury via renal vascular effects. Kidney Int., 2006, 69(9), 1535-1542.
-
(2006)
Kidney Int
, vol.69
, Issue.9
, pp. 1535-1542
-
-
Yasuda, H.1
Yuen, P.S.2
Hu, X.3
Zhou, H.4
Star, R.A.5
-
10
-
-
33645008770
-
Statins attenuate sepsis
-
Spitzer, A.L.; Harris, H.W. Statins attenuate sepsis. Surgery, 2006, 139(3), 283-287.
-
(2006)
Surgery
, vol.139
, Issue.3
, pp. 283-287
-
-
Spitzer, A.L.1
Harris, H.W.2
-
11
-
-
29844445926
-
Statin therapy is associated with fewer deaths in patients with bacteraemia
-
Kruger, P.; Fitzsimmons, K.; Cook, D.; Jones, M.; Nimmo, G. Statin therapy is associated with fewer deaths in patients with bacteraemia. Intensive Care Med., 2006, 32(1), 75-79.
-
(2006)
Intensive Care Med
, vol.32
, Issue.1
, pp. 75-79
-
-
Kruger, P.1
Fitzsimmons, K.2
Cook, D.3
Jones, M.4
Nimmo, G.5
-
12
-
-
33846430527
-
Nonuse of statins--a new risk factor for infectious death in cardiovascular patients?
-
Kruger, S.; Merx, M.W. Nonuse of statins--a new risk factor for infectious death in cardiovascular patients? Crit. Care Med., 2007, 35(2), 631-632.
-
(2007)
Crit. Care Med
, vol.35
, Issue.2
, pp. 631-632
-
-
Kruger, S.1
Merx, M.W.2
-
13
-
-
34247150706
-
Statins and sepsis: Multiple modifications at multiple levels
-
Terblanche, M.; Almog, Y.; Rosenson, R.S.; Smith, T.S.; Hackam, D.G. Statins and sepsis: multiple modifications at multiple levels. Lancet Infect. Dis., 2007, 7(5), 358-368.
-
(2007)
Lancet Infect. Dis
, vol.7
, Issue.5
, pp. 358-368
-
-
Terblanche, M.1
Almog, Y.2
Rosenson, R.S.3
Smith, T.S.4
Hackam, D.G.5
-
14
-
-
62249217244
-
Statin therapy is associated with decreased mortality in patients with infection
-
Donnino, M.W.; Cocchi, M.N.; Howell, M.; Clardy, P.; Talmor, D.; Cataldo, L.; Chase, M.; Al-Marshad, A.; Ngo, L.; Shapiro, N.I. Statin therapy is associated with decreased mortality in patients with infection. Acad. Emerg. Med., 2009, 16(3), 230-234.
-
(2009)
Acad. Emerg. Med
, vol.16
, Issue.3
, pp. 230-234
-
-
Donnino, M.W.1
Cocchi, M.N.2
Howell, M.3
Clardy, P.4
Talmor, D.5
Cataldo, L.6
Chase, M.7
Al-Marshad, A.8
Ngo, L.9
Shapiro, N.I.10
-
15
-
-
66749164929
-
Reduction in mortality associated with statin therapy in patients with severe sepsis
-
Dobesh, P.P.; Klepser, D.G.; McGuire, T.R.; Morgan, C.W.; Olsen, K.M. Reduction in mortality associated with statin therapy in patients with severe sepsis. Pharmacotherapy, 2009, 29(6), 621-630.
-
(2009)
Pharmacotherapy
, vol.29
, Issue.6
, pp. 621-630
-
-
Dobesh, P.P.1
Klepser, D.G.2
McGuire, T.R.3
Morgan, C.W.4
Olsen, K.M.5
-
16
-
-
77249126866
-
Statins for community-acquired pneumonia: Current state of the science
-
Viasus, D.; Garcia-Vidal, C.; Gudiol, F.; Carratala, J. Statins for community-acquired pneumonia: current state of the science. Eur. J. Clin. Microbiol. Infect. Dis., 2010, 29(2), 143-152.
-
(2010)
Eur. J. Clin. Microbiol. Infect. Dis
, vol.29
, Issue.2
, pp. 143-152
-
-
Viasus, D.1
Garcia-Vidal, C.2
Gudiol, F.3
Carratala, J.4
-
17
-
-
33646483036
-
Systemic infections can decrease the threshold of statin-induced muscle injury
-
Mahboobi, S.K.; Shohat, E.Z.; Jellinek, S.P.; Rose, M. Systemic infections can decrease the threshold of statin-induced muscle injury. South Med. J., 2006, 99(4), 403-404.
-
(2006)
South Med. J
, vol.99
, Issue.4
, pp. 403-404
-
-
Mahboobi, S.K.1
Shohat, E.Z.2
Jellinek, S.P.3
Rose, M.4
-
18
-
-
33646390136
-
Statins for sepsis: A cautionary note
-
Vincent, A.; Miller, J.A. Statins for sepsis: a cautionary note. Intensive Care Med., 2006, 32(5), 795.
-
(2006)
Intensive Care Med
, vol.32
, Issue.5
, pp. 795
-
-
Vincent, A.1
Miller, J.A.2
-
19
-
-
33846454336
-
Statins and sepsis: Panacea or Pandora's box?
-
author reply 80-81
-
Drage, S.M.; Barber, V.S.; Young, J.D. Statins and sepsis: panacea or Pandora's box? Lancet Infect Dis., 2007, 7(2), 80; author reply 80-81.
-
(2007)
Lancet Infect Dis
, vol.7
, Issue.2
, pp. 80
-
-
Drage, S.M.1
Barber, V.S.2
Young, J.D.3
-
20
-
-
59549089180
-
Statin adverse effects: A review of the literature and evidence for a mitochondrial mechanism
-
Golomb, B.A.; Evans, M.A. Statin adverse effects: a review of the literature and evidence for a mitochondrial mechanism. Am. J. Cardiovasc. Drugs, 2008, 8(6), 373-418.
-
(2008)
Am. J. Cardiovasc. Drugs
, vol.8
, Issue.6
, pp. 373-418
-
-
Golomb, B.A.1
Evans, M.A.2
-
21
-
-
65449182012
-
Statins for sepsis: A critical and updated review
-
Kopterides, P.; Falagas, M.E. Statins for sepsis: a critical and updated review. Clin. Microbiol. Infect., 2009, 15(4), 325-334.
-
(2009)
Clin. Microbiol. Infect
, vol.15
, Issue.4
, pp. 325-334
-
-
Kopterides, P.1
Falagas, M.E.2
-
22
-
-
0141891106
-
Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection
-
Kadurugamuwa, J.L.; Sin, L.V.; Yu, J.; Francis, K.P.; Kimura, R.; Purchio, T.; Contag, P.R. Rapid direct method for monitoring antibiotics in a mouse model of bacterial biofilm infection. Antimicrob. Agents Chemother., 2003, 47(10), 3130-3137.
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, Issue.10
, pp. 3130-3137
-
-
Kadurugamuwa, J.L.1
Sin, L.V.2
Yu, J.3
Francis, K.P.4
Kimura, R.5
Purchio, T.6
Contag, P.R.7
-
23
-
-
0034669924
-
Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice
-
Akinbi, H.T.; Epaud, R.; Bhatt, H.; Weaver, T.E. Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice. J. Immunol., 2000, 165(10), 5760-5766.
-
(2000)
J. Immunol
, vol.165
, Issue.10
, pp. 5760-5766
-
-
Akinbi, H.T.1
Epaud, R.2
Bhatt, H.3
Weaver, T.E.4
-
24
-
-
57049189591
-
T. Tissue factor as an initiator of coagulation and inflammation in the lung
-
van der Poll, T. Tissue factor as an initiator of coagulation and inflammation in the lung. Crit. Care, 2008, 12(Suppl 6), S3.
-
(2008)
Crit. Care
, vol.12
, Issue.SUPPL. 6
, pp. 3
-
-
van der Poll1
-
25
-
-
0141819138
-
The protein C pathway
-
Esmon, C.T. The protein C pathway. Chest, 2003, 124(3 Suppl), 26S-32S.
-
(2003)
Chest
, vol.124
, Issue.3 SUPPL
-
-
Esmon, C.T.1
-
26
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard, G.R.; Vincent, J.L.; Laterre, P.F.; LaRosa, S.P.; Dhainaut, J.F.; Lopez-Rodriguez, A.; Steingrub, J.S.; Garber, G.E.; Helterbrand, J.D.; Ely, E.W.; Fisher, C.J., Jr. Efficacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med., 2001, 344(10), 699-709.
-
(2001)
N. Engl. J. Med
, vol.344
, Issue.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
Larosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr., C.J.11
-
27
-
-
67849101852
-
The protein C pathway and pathologic processes
-
Castellino, F.J.; Ploplis, V.A. The protein C pathway and pathologic processes. J. Thromb. Haemost., 2009, 7(Suppl 1), 140-145.
-
(2009)
J. Thromb. Haemost
, vol.7
, Issue.SUPPL. 1
, pp. 140-145
-
-
Castellino, F.J.1
Ploplis, V.A.2
-
28
-
-
0037117639
-
Statin prevents tissue factor expression in human endothelial cells: Role of Rho/Rho-kinase and Akt pathways
-
Eto, M.; Kozai, T.; Cosentino, F.; Joch, H.; Luscher, T.F. Statin prevents tissue factor expression in human endothelial cells: role of Rho/Rho-kinase and Akt pathways. Circulation, 2002, 105(15), 1756-1759.
-
(2002)
Circulation
, vol.105
, Issue.15
, pp. 1756-1759
-
-
Eto, M.1
Kozai, T.2
Cosentino, F.3
Joch, H.4
Luscher, T.F.5
-
29
-
-
0035895319
-
An HMG-CoAreductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro
-
Aikawa, M.; Rabkin, E.; Sugiyama, S.; Voglic, S.J.; Fukumoto, Y.; Furukawa, Y.; Shiomi, M.; Schoen, F.J.; Libby, P. An HMG-CoAreductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation, 2001, 103(2), 276-283.
-
(2001)
Circulation
, vol.103
, Issue.2
, pp. 276-283
-
-
Aikawa, M.1
Rabkin, E.2
Sugiyama, S.3
Voglic, S.J.4
Fukumoto, Y.5
Furukawa, Y.6
Shiomi, M.7
Schoen, F.J.8
Libby, P.9
-
30
-
-
38349103047
-
Unexpected antimicrobial effect of statins
-
Jerwood, S.; Cohen, J. Unexpected antimicrobial effect of statins. J. Antimicrob. Chemother., 2008, 61(2), 362-364.
-
(2008)
J. Antimicrob. Chemother
, vol.61
, Issue.2
, pp. 362-364
-
-
Jerwood, S.1
Cohen, J.2
-
31
-
-
42449120103
-
Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance. Surg
-
Chaudhry, M.Z.; Wang, J.H.; Blankson, S.; Redmond, H.P. Statin (cerivastatin) protects mice against sepsis-related death via reduced proinflammatory cytokines and enhanced bacterial clearance. Surg. Infect., (Larchmt) 2008, 9(2), 183-194.
-
(2008)
Infect., (Larchmt)
, vol.9
, Issue.2
, pp. 183-194
-
-
Chaudhry, M.Z.1
Wang, J.H.2
Blankson, S.3
Redmond, H.P.4
-
32
-
-
0030024585
-
Carcinogenicity of lipid-lowering drugs
-
Newman, T.B.; Hulley, S.B. Carcinogenicity of lipid-lowering drugs. JAMA, 1996, 275(1), 55-60.
-
(1996)
JAMA
, vol.275
, Issue.1
, pp. 55-60
-
-
Newman, T.B.1
Hulley, S.B.2
|