Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells

Toxicology Letters

Volumn 199, Issue 3, 2010, Pages 277-287

  Qi, Xu Feng ^a,b   Kim, Dong Heui ^b   Yoon, Yang Suk ^b   Kim, Soo Ki ^b   Cai, Dong Qing ^a   Teng, Yung Chien ^b   Shim, Kwang Yong ^b   Lee, Kyu Jae ^b  

^a JINAN UNIVERSITY   (China)

^b Yonsei University Wonju College of Medicine   (South Korea)

Author keywords

Apoptosis; CT26 cells; Oxidative stress; Simvastatin

Indexed keywords

ACETYLCYSTEINE; BUTHIONINE SULFOXIMINE; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CATALASE; FARNESYL DIPHOSPHATE; GERANYLGERANYL PYROPHOSPHATE; GLUTATHIONE; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; MEVALONOLACTONE; SIMVASTATIN; SUPEROXIDE DISMUTASE; UBIDECARENONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL DEATH; CELL VIABILITY; COLON CARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; GLUTATHIONE METABOLISM; MELANOMA CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; BUTHIONINE SULFOXIMINE; CELL LINE, TUMOR; COLONIC NEOPLASMS; GLUTATHIONE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MICE; OLIGOPEPTIDES; OXIDATIVE STRESS; POLYISOPRENYL PHOSPHATES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIMVASTATIN;

MURINAE;

EID: 78650510991     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.09.010     Document Type: Article

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