Mechanism of sappanchalcone-induced growth inhibition and apoptosis in human oral cancer cells

Toxicology in Vitro

Volumn 25, Issue 8, 2011, Pages 1782-1788

  Lee, Young Man ^a   Kim, Youn Chul ^b   Choi, Byeong Jun ^a   Lee, Deok Won ^a   Yoon, Jung Hoon ^c   Kim, Eun Cheol ^a  

^a Kyung Hee University   (South Korea)

^b Wonkwang University   (South Korea)

^c Chosun University   (South Korea)

Author keywords

Apoptosis; MAPK; Mitochondria; NF kB; Oral cancer cells; Sappanchalcone

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; FLAVONOID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SAPPANCHALCONE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS POTENTIAL; MOUTH CANCER; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONES; HUMANS; I-KAPPA B PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MOUTH NEOPLASMS; NF-KAPPA B; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; TUMOR SUPPRESSOR PROTEIN P53;

CAESALPINIA SAPPAN;

EID: 82655162047     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.09.009     Document Type: Article

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