Anti-cancer activity of highly purified sulfur in immortalized and malignant human oral keratinocytes

Toxicology in Vitro

Volumn 22, Issue 1, 2008, Pages 87-95

  Lee, Jun ^a   Lee, Hwa Jeong ^a   Park, Jong Dae ^a   Lee, Sun Kyung ^a   Lee, Sang Im ^a   Lim, Hyun Dae ^a   Lee, You Mee ^a   Yun, Young Gab ^b   Jeon, Byung Hun ^b   Ree, In Soo ^c   Jun, Chang Duk ^d   Lee, Suk Keun ^e   Kim, Eun Cheol ^a  

^a Wonkwang University   (South Korea)

^b Wonkwang University   (South Korea)

^c 21th R and D Co   (South Korea)

^d Gwangju Institute of Science and Technology (GIST)   (South Korea)

^e Gangneung Wonju National University   (South Korea)

Author keywords

Apoptosis; Cell cycle arrest; Chemoprevention; Immortalized keratinocytes; Oral cancer; Purified sulfur

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CASPASE 3; CYCLIN D1; CYCLIN D2; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN E; CYTOCHROME C; DNA FRAGMENT; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SULFUR;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL IMMORTALIZATION; CELL NUCLEUS; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTURE MEDIUM; CYTOSOL; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG PURITY; ENZYME ACTIVATION; GROWTH INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MOUTH CARCINOMA; NITROBLUE TETRAZOLIUM TEST; PROTEIN EXPRESSION; PROTEIN INDUCTION; SQUAMOUS CELL CARCINOMA; TIME; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; KERATINOCYTES; MOUTH NEOPLASMS; NEOPLASM STAGING; SULFUR COMPOUNDS; TIME FACTORS;

EID: 37249033214     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.08.016     Document Type: Article

References (32)

1. Amagase H., and Milner J.A. Impact of various sources of garlic and their constituents on 7,12-dimethylbenz[a]anthracene binding to mammary cell DNA. Carcinogenesis 14 (1993) 1627-1631
2. Ashkenazi A., and Dixit V.M. Apoptosis control by death and decoy receptors. Current Opinion Cell Biology 11 (1999) 255-260
3. Boukamp P., Petrussevska R.T., Breitkreutz D., Hornug J., Markham A., and Fusenig N.E. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. Journal of Cell Biology 106 (1988) 761-771
4. Cardinali M.H., Pietraszkiewicz J.F., and Robbins K.C. Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies. International Journal of Cancer 61 (1995) 98-103
5. Cassileth B.R., and Chapman C.C. Alternative and complementary cancer therapies. Cancer 77 (1996) 1026-1034
6. Gartel A.L., and Tyner A.L. Transcriptional regulation of the p21(WAF1/CIP1) gene. Experimental Cell Research 246 (1999) 280-289
7. Hartwell L.H., and Kastan M.B. Cell cycle control and cancer. Science 266 (1994) 1821-1828
8. Herman-Antosiewicz A., and Singh S.V. Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review. Mutation Research 555 (2004) 121-131
9. n species. Chemical Physics Letters 267 (1997) 65-717
10. Hussain S.P., Jannu L.N., and Rao A.R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. Cancer Letters 49 (1990) 175-180
11. Jaliehvand F. Sulfur: not a "silent" element any more. Chemistry Society Reviews 35 (2006) 1256-1268
12. WAF1/CIP1 in head and neck cancer cells. American Journal of Chinese Medicine 33 (2005) 405-414
13. Lee H.J., Son D.H., Lee S.K., Lee J., Jun C.D., Jeon B.H., Lee S.K., and Kim E.C. Extract of Coptidis rhizoma induce cytochrome c-dependent apoptosis in immortalized and malignant human oral keratinocytes. Phytotherapy Research 20 (2006) 773-779
14. Lee S.K., Jang H.J., Lee H.J., Lee J., Jeon B.H., Jun C.D., Lee S.K., and Kim E.C. p38 and ERK MAP kinase mediates iron-chelator induced apoptosis and suppressed differentiation in immortalized and malignant human oral keratinocytes. Life Science 79 (2006) 1419-1427
15. Lee S.K., Kim H.S., Lee H.J., Lee J., Jeon B.H., Jun C.D., Lee S.K., and Kim E.C. Dual effect of nitric oxide in immortalized and malignant human oral keratinocytes: induction of apoptosis and differentiation. Journal of Oral Pathology and Medicine 35 (2006) 352-360
16. Lee S.K., Lee J.J., Lee H.J., Lee J., Jeon B.H., Jun C.D., Lee S.K., and Kim E.C. Iron chelator-induced growth arrest and cytochrome c-dependent apoptosis in immortalized and malignant oral keratinocytes. Journal of Oral Pathology and Medicine 35 (2006) 218-226
17. Luo T., Chen L., Bao K., Yu W., and Qian Y. Solvothermal preparation of amorphous carbon nanotubes and Fe/C coaxial nanocables from sulfur, ferrocene, and benzene. Carbon 44 (2006) 2816-2821
18. Marcus B., Arenberg D., Lee J., Kleer C., Chepeha D.B., Schmalbach C.E., Islam M., Paul S., Pan Q., Hanash S., Kuick R., Merajver S.D., and Teknos T.N. Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma. Cancer 101 (2004) 2779-2787
19. McCann J. Texas center studies research alternative treatments. Journal of National Cancer Institute 15 (1997) 1485-1486
20. Oh S.H., Lee B.H., and Lim S.C. Cadmium induces apoptotic cell death in WI 38 cells via caspase-dependent Bid cleavage and calpain-mediated mitochondrial Bax cleavage by Bcl-2-independent pathway. Biochemical Pharmacology 68 (2004) 1845-1855
21. Parcell S. Sulfur in human nutrition and applications in medicine. Alternative Medical Reviews 7 (2002) 22-44
22. Pietra G., Mortarini R., Parmiani G., and Anichini A. Phases of apoptosis of melanoma cells, but not of normal melanocytes, differently affect maturation of myeloid dendritic cells. Cancer Research 61 (2001) 8218-8826
23. Reed S.I. Control of the G1/S transition. Cancer Surveys 29 (1997) 7-23
24. Reed J.C. Dysregulation of apoptosis in cancer. American Journal of Clinical Oncology 17 (1999) 2941-2953
25. Shukla Y., Shingh A., and Srivastava B. Inhibition of carcinogen-induced activity of gamma-glutamyl transpeptidase by certain dietary constituents in mouse skin. Biomedical Environmental Science 12 (1999) 110-115
26. Smirnova O.V., Saliev V.P., and Klemparskaia N.N. Purified sulfur as an agent to relieve the side effects in the radiation therapy of cervical cancer. Medical Radiology 36 (1991) 16-19
27. Song K., and Milner J.A. Heating garlic inhibits its ability to suppress 7,12-dimethylbenz [a] anthracene-induced DNA adduct formation in rat mammary tissue. Journal of Nutrition 129 (1999) 657-661
28. Sumiyoshi H., and Wargovich M.J. Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds. Cancer Research 50 (1990) 5084-5087
29. Sun X.M., MacFarlane M., Zhuang J., Wolf B.B., Green D.R., and Cohen G.M. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. Journal of Biological Chemistry 274 (1999) 5053-5060
30. Wargovich M.J., Woods C., Eng V.W., Stephens L.C., and Gray K. Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide. Cancer Research 48 (1988) 6872-6875
31. Wu X., Kassie F., and Mersch-Sundermann V. Induction of apoptosis in tumor cells by naturally occurring sulfur-containing compounds. Mutation Research 589 (2005) 81-102
32. Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., Cai J., Peng T.I., Jones D.P., and Wang X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275 (1997) 1129-1132