Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling

Cancer Research

Volumn 64, Issue 17, 2004, Pages 6349-6356

  Mallikarjuna, Gu ^a   Dhanalakshmi, Sivanandhan ^a   Singh, Rana P ^a   Agarwal, Chapla ^a,b   Agarwal, Rajesh ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; DNA NUCLEOTIDYLEXOTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN P21; PROTEIN P27; PROTEIN P53; SILIBININ; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INCIDENCE; CANCER PREVENTION; CARCINOGENESIS; CELL CYCLE; CELL LYSATE; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; DIET; DNA SYNTHESIS; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVATION; FEEDING; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LIGHT; MOLECULAR BIOLOGY; MOUSE; MOUSE STRAIN; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RADIATION EXPOSURE; REGULATORY MECHANISM; SKIN CANCER; TUMOR VOLUME; ULTRAVIOLET B RADIATION; UPREGULATION; WESTERN BLOTTING;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANIMALS; APOPTOSIS; BROMODEOXYURIDINE; CASPASE 3; CASPASES; CELL CYCLE PROTEINS; CELL DIVISION; ENZYME ACTIVATION; FEMALE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED HRS; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS, RADIATION-INDUCED; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SILYMARIN; SKIN; SKIN NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 4344639798     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-04-1632     Document Type: Article

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