Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formation

Journal of Combinatorial Chemistry

Volumn 8, Issue 4, 2006, Pages 531-539

  Xu, Yang ^a   Lu, Hong ^b   Kennedy, Jack P ^a   Yan, Xuxia ^b   McAllister, Laura A ^a   Yamamoto, Noboru ^a   Moss, Jason A ^a,c   Boldt, Grant E ^a   Jiang, Shibo ^b   Janda, Kim D ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b NEW YORK BLOOD CENTER   (United States)

^c C S Bio Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL LINE; CELL MEMBRANE; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; EVALUATION; HUMAN; MEMBRANE FUSION; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; SYNTHESIS; ULTRAVIOLET SPECTROPHOTOMETRY;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; DRUG EVALUATION, PRECLINICAL; HIV ENVELOPE PROTEIN GP41; HIV FUSION INHIBITORS; HUMANS; MEMBRANE FUSION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 33746357565     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc0600167     Document Type: Article

References (45)

1. Chan, D. C.; Chutkowski, C. T.; Kim, P. S. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 15613-15617.
2. Chan, D. C.; Pass, D.; Berger, J. M.; Kim, P. S. Cell 1997, 89, 263-273.
3. Ketas, T. J.; Klasse, P. J.; Spenlehauer, C.; Nesin, M.; Frank, I.; Pope, M.; Strizki, J. M.; Reyes, G. R.; Baroudy, B. M.; Moore, J. P. AIDS Res. Hum. Retroviruses 2003, 19, 177-186.
4. Liu, S. W.; Jiang, S. B. Curr. Pharm. Des. 2004, 10, 1827-1843.
5. Moore, J. P.; Doms, R. W. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 10598-10602.
6. Fauci, A. S. Nat. Med. 2003, 9, 839-843.
7. Pomerantz, R. J.; Horn, D. L. Nat. Med. 2003, 9, 867-873.
8. Chan, D. C.; Kim, P. S. Cell 1998, 93, 681-684.
9. Jiang, S.; Siddiqui, P.; Liu, S. Drug Discovery Today: Therapeutic Strategies 2004, 1, 497-503.
10. Jiang, S. B.; Zhao, Q.; Debnath, A. K. Curr. Pharm. Des. 2002, 8, 563-580.
11. Chen, S. S. L. Intervirology 1996, 39, 242-248.
12. Sattentau, Q. J.; Moore, J. P.; Vignaux, F.; Traincard, F.; Poignard, P. J. Virol. 1993, 67, 7383-7393.
13. Berger, E. A.; Murphy, P. M.; Farber, J. M. Annu. Rev. Immunol. 1999, 17, 657-700.
14. Lu, M.; Kim, P. S. J. Biomol. Struct. Dyn. 1997, 15, 465-471.
15. Weissenhorn, W.; Dessen, A.; Harrison, S. C.; Skehel, J. J.; Wiley, D. C. Nature 1997, 387, 426-430.
16. Jiang, S. B.; Lin, K.; Strick, N.; Neurath, A. R. Nature 1993, 365, 113-113.
17. Wild, C.; Oas, T.; McDanal, C.; Bolognesi, D.; Matthews, T. J. Cell. Biol. 1993, 222-222.
18. Wild, C. T.; Shugars, D. C.; Greenwell, T. K.; McDanal, C. B.; Matthews, T. J. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 9770-9774.
19. Chen, R. Y.; Kilby, J. M.; Saag, M. S. Expert Opin. Invest. Drugs 2002, 11, 1837-1843.
20. Bianchi, E.; Finotto, M.; Ingallinella, P.; Hrin, R.; Carella, A. V.; Hou, X. S.; Schleif, W. A.; Miller, M. D.; Geleziunas, R.; Pessi, A. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 12903-12908.
21. Ferrer, M.; Kapoor, T. M.; Strassmaier, T.; Weissenhorn, W.; Skehel, J. J.; Oprian, D.; Schreiber, S. L.; Wiley, D. C.; Harrison, S. C. Nat. Struct. Biol. 1999, 6, 953-960.
22. Jiang, S. B.; Lu, H.; Liu, S. W.; Zhao, Q.; He, Y. X.; Debnath, A. K. Antimicrob. Agents Chemother. 2004, 48, 4349-4359.
23. Liu, S. W.; Lu, H.; Zhao, Q.; He, Y. X.; Niu, J. K.; Debnath, A. K.; Wu, S. G.; Jiang, S. B. Biochim. Biophys. Acta 2005, 1723, 270-281.
24. Xu, Y.; Shi, J.; Yamamoto, N.; Moss, J. A.; Vogt, P. K.; Janda, K. D. Bioorg. Med. Chem. 2005, 14, 2660-2673.
25. Dickerson, T. J.; Beuscher, A. E.; Hixon, M. S.; Yamamoto, N.; Xu, Y.; Olson, A. J.; Janda, K. D. Biochemistry 2005, 44, 14845-14853.
26. Bogan, A. A.; Thorn, K. S. J. Mol. Biol. 1998, 280, 1-9.
27. Berg, T. ChemBioChem 2004, 5, 1051-1053.
28. Ugi, I.; Meyr, R. Angew. Chem.-Int. Ed. 1958, 70, 702-703.
29. Domling, A.; Ugi, I. Angew. Chem., Int. Ed. 2000, 39, 3169-3210.
30. Jiang, S. B.; Lin, K.; Zhang, L.; Debnath, A. K. J, Virol. Methods 1999, 80, 85-96.
31. Passerini, M. Gazz. Chim. Ital. 1921, 51, 126.
32. Passerini, M. Gazz. Chim. Ital. 1921, 51, 181.
33. Jiang, S.; Boyer-Chatenet, L. Antiviral Res. 2002, 53, A69-A69.
34. Raviv, Y.; Viard, M.; Bess, J.; Blumenthal, R. Virology 2002, 293, 243-251.
35. Jiang, S.; Lin, K.; Neurath, A. R. J. Exp. Med. 1991, 174, 1557-1563.
36. Zhao, Q.; Ernst, J. T.; Hamilton, A. D.; Debnath, A. K.; Jiang, S. B. AIDS Res. Hum. Retroviruses 2002, 18, 989-997.
37. De Clercq, E. Med. Chem. Res. 2004, 13, 439-478.
38. Arkin, M. R.; Wells, J. A. Nat. Rev. Drug Discovery 2004, 3, 301-317.
39. Gadek, T. R.; Nicholas, J. B. Biochem. Pharmacol. 2003, 65, 1-8.
40. Ji, H.; Shu, W.; Burling, F. T.; Jiang, S. B.; Lu, M. J. Virol. 1999, 73, 8578-8586.
41. Zhou, G. F.; Ferrer, M.; Chopra, R.; Kapoor, T. M.; Strassmaier, T.; Weissenhorn, W.; Skehel, J. J.; Oprian, D.; Schreiber, S. L.; Harrison, S. C.; Wiley, D. C. Bioorg. Med. Chem. 2000, 8, 2219-2227.
42. Debnath, A. K.; Radigan, L.; Jiang, S. B. J. Med. Chem. 1999, 42, 3203-3209.
43. Liu, S. W.; Boyer-Chatenet, L.; Lu, H.; Jiang, S. B. J. Biomol Screening 2003, 8, 685-693.
44. Liu, S. W.; Zhao, Q.; Jiang, S. B. Peptides 2003, 24, 1303-1313.
45. Chou, T. C.; Hayball, M. P. CalcuSyn: Windows software for dose effect analysis; BIOSOFT: Ferguson, MO 63135, 1991.