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Volumn 21, Issue 3, 2005, Pages 101-104

Mining nematode genome data for novel drug targets

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; ANTIBIOTIC AGENT; IVERMECTIN; TETRACYCLINE DERIVATIVE;

EID: 13944271473     PISSN: 14714922     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pt.2004.12.002     Document Type: Short Survey
Times cited : (25)

References (30)
  • 1
    • 0038307857 scopus 로고    scopus 로고
    • 400 000 nematode ESTs on the net
    • J. Parkinson 400 000 nematode ESTs on the net Trends Parasitol. 19 2003 283 286
    • (2003) Trends Parasitol. , vol.19 , pp. 283-286
    • Parkinson, J.1
  • 2
    • 0346494825 scopus 로고    scopus 로고
    • Nematode.net: A tool for navigating sequences from parasitic and free-living nematodes
    • T. Wylie Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes Nucleic Acids Res. 32 2004 D423 D426
    • (2004) Nucleic Acids Res. , vol.32
    • Wylie, T.1
  • 3
    • 0347755536 scopus 로고    scopus 로고
    • NEMBASE: A resource for parasitic nematode ESTs
    • J. Parkinson NEMBASE: a resource for parasitic nematode ESTs Nucleic Acids Res. 32 2004 D427 D430
    • (2004) Nucleic Acids Res. , vol.32
    • Parkinson, J.1
  • 4
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • The C. elegans Sequencing Consortium
    • The C. elegans Sequencing Consortium Genome sequence of the nematode C. elegans: a platform for investigating biology Science 282 1998 2012 2018
    • (1998) Science , vol.282 , pp. 2012-2018
  • 5
    • 4243088097 scopus 로고    scopus 로고
    • The genome sequence of Caenorhabditis briggsae: A platform for comparative genomics
    • L.D. Stein The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics PLoS Biol. 1 2003 166 192
    • (2003) PLoS Biol. , vol.1 , pp. 166-192
    • Stein, L.D.1
  • 6
    • 1942537079 scopus 로고    scopus 로고
    • First sequenced genome of a parasitic nematode
    • E. Ghedin First sequenced genome of a parasitic nematode Trends Parasitol. 20 2004 151 153
    • (2004) Trends Parasitol. , vol.20 , pp. 151-153
    • Ghedin, E.1
  • 7
    • 0346494826 scopus 로고    scopus 로고
    • WormBase: A multi-species resource for nematode biology and genomics
    • T.W. Harris WormBase: a multi-species resource for nematode biology and genomics Nucleic Acids Res. 32 2004 D411 D417
    • (2004) Nucleic Acids Res. , vol.32
    • Harris, T.W.1
  • 8
    • 0032033513 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model for parasitic nematodes
    • T.R. Burglin Caenorhabditis elegans as a model for parasitic nematodes Int. J. Parasitol. 28 1998 395 411
    • (1998) Int. J. Parasitol. , vol.28 , pp. 395-411
    • Burglin, T.R.1
  • 9
    • 0035414430 scopus 로고    scopus 로고
    • Caenorhabditis elegans and the study of gene function in parasites
    • S. Hashmi Caenorhabditis elegans and the study of gene function in parasites Trends Parasitol. 17 2001 387 393
    • (2001) Trends Parasitol. , vol.17 , pp. 387-393
    • Hashmi, S.1
  • 10
    • 0035935627 scopus 로고    scopus 로고
    • Caenorhabditis elegans: How good a model for veterinary parasites?
    • T.G. Geary, and D.P. Thompson Caenorhabditis elegans: how good a model for veterinary parasites? Vet. Parasitol. 101 2001 371 386
    • (2001) Vet. Parasitol. , vol.101 , pp. 371-386
    • Geary, T.G.1    Thompson, D.P.2
  • 11
    • 0032804209 scopus 로고    scopus 로고
    • Parasitic helminth genomics
    • M. Blaxter Parasitic helminth genomics Parasitology 118 Suppl. 1999 39 51
    • (1999) Parasitology , vol.118 , Issue.SUPPL. , pp. 39-51
    • Blaxter, M.1
  • 12
    • 0037157590 scopus 로고    scopus 로고
    • Drug development for neglected diseases: A deficient market and a public-health policy failure
    • P. Trouiller Drug development for neglected diseases: a deficient market and a public-health policy failure Lancet 359 2002 2188 2194
    • (2002) Lancet , vol.359 , pp. 2188-2194
    • Trouiller, P.1
  • 13
    • 0034029917 scopus 로고    scopus 로고
    • Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics
    • C.H. Lai Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics Genome Res. 10 2000 703 713
    • (2000) Genome Res. , vol.10 , pp. 703-713
    • Lai, C.H.1
  • 14
    • 0037228888 scopus 로고    scopus 로고
    • A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum
    • R.F. Waller A type II pathway for fatty acid biosynthesis presents drug targets in Plasmodium falciparum Antimicrob. Agents Chemother. 47 2003 297 301
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 297-301
    • Waller, R.F.1
  • 15
    • 0033520336 scopus 로고    scopus 로고
    • Inhibitors of the non-mevalonate pathway of isoprenoid biosynthesis as antimalarial drug targets
    • H. Jomaa Inhibitors of the non-mevalonate pathway of isoprenoid biosynthesis as antimalarial drug targets Science 285 1999 1573 1576
    • (1999) Science , vol.285 , pp. 1573-1576
    • Jomaa, H.1
  • 16
    • 0037308581 scopus 로고    scopus 로고
    • Fosmidomycin, a novel chemotherapeutic agent for malaria
    • B. Lell Fosmidomycin, a novel chemotherapeutic agent for malaria Antimicrob. Agents Chemother. 47 2003 735 738
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 735-738
    • Lell, B.1
  • 17
    • 0035850250 scopus 로고    scopus 로고
    • Wolbachia in filarial nematodes: Evolutionary aspects and implications for the pathogenesis and treatment of filarial diseases
    • C. Bandi Wolbachia in filarial nematodes: evolutionary aspects and implications for the pathogenesis and treatment of filarial diseases Vet. Parasitol. 98 2001 215 238
    • (2001) Vet. Parasitol. , vol.98 , pp. 215-238
    • Bandi, C.1
  • 18
    • 0142072853 scopus 로고    scopus 로고
    • Doxycycline as a novel strategy against bancroftian filariasis - Depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production
    • A. Hoerauf Doxycycline as a novel strategy against bancroftian filariasis - depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfilaria production Med. Microbiol. Immunol. (Berl.) 192 2003 211 216
    • (2003) Med. Microbiol. Immunol. (Berl.) , vol.192 , pp. 211-216
    • Hoerauf, A.1
  • 19
    • 11144354770 scopus 로고    scopus 로고
    • Construction of BAC libraries from the parasitic nematode Brugia malayi and physical mapping of the genome of its Wolbachia endosymbiont
    • J. Foster Construction of BAC libraries from the parasitic nematode Brugia malayi and physical mapping of the genome of its Wolbachia endosymbiont Int. J. Parasitol. 34 2004 733 746
    • (2004) Int. J. Parasitol. , vol.34 , pp. 733-746
    • Foster, J.1
  • 20
    • 0033198944 scopus 로고    scopus 로고
    • RNA-triggered gene silencing
    • A. Fire RNA-triggered gene silencing Trends Genet. 15 1999 358 363
    • (1999) Trends Genet. , vol.15 , pp. 358-363
    • Fire, A.1
  • 21
    • 0036079595 scopus 로고    scopus 로고
    • Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference
    • A.S. Hussein Suppression of secreted acetylcholinesterase expression in Nippostrongylus brasiliensis by RNA interference Mol. Biochem. Parasitol. 122 2002 91 94
    • (2002) Mol. Biochem. Parasitol. , vol.122 , pp. 91-94
    • Hussein, A.S.1
  • 22
    • 0036679383 scopus 로고    scopus 로고
    • Ingestion of double-stranded RNA by preparasitic juvenile cyst nematodes leads to RNA interference
    • P.E. Urwin Ingestion of double-stranded RNA by preparasitic juvenile cyst nematodes leads to RNA interference Mol. Plant Microbe Interact. 15 2002 747 752
    • (2002) Mol. Plant Microbe Interact. , vol.15 , pp. 747-752
    • Urwin, P.E.1
  • 23
    • 0038512548 scopus 로고    scopus 로고
    • Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayi
    • A.A. Aboobaker, and M.L. Blaxter Use of RNA interference to investigate gene function in the human filarial nematode parasite Brugia malayi Mol. Biochem. Parasitol. 129 2003 41 51
    • (2003) Mol. Biochem. Parasitol. , vol.129 , pp. 41-51
    • Aboobaker, A.A.1    Blaxter, M.L.2
  • 24
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • R.S. Kamath Systematic functional analysis of the Caenorhabditis elegans genome using RNAi Nature 421 2003 231 237
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1
  • 25
    • 0035834760 scopus 로고    scopus 로고
    • Expression and secretion of a larval-specific chitinase (family 18 glycosyl hydrolase) by the infective stages of the parasitic nematode, Onchocerca volvulus
    • Y. Wu Expression and secretion of a larval-specific chitinase (family 18 glycosyl hydrolase) by the infective stages of the parasitic nematode, Onchocerca volvulus J. Biol. Chem. 276 2001 42557 42564
    • (2001) J. Biol. Chem. , vol.276 , pp. 42557-42564
    • Wu, Y.1
  • 26
    • 0034494290 scopus 로고    scopus 로고
    • Chitin synthase in the filarial parasite, Brugia malayi
    • M.T. Harris Chitin synthase in the filarial parasite, Brugia malayi Mol. Biochem. Parasitol. 111 2000 351 362
    • (2000) Mol. Biochem. Parasitol. , vol.111 , pp. 351-362
    • Harris, M.T.1
  • 27
    • 0037197901 scopus 로고    scopus 로고
    • Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans
    • J.L. Watts, and J. Browse Genetic dissection of polyunsaturated fatty acid synthesis in Caenorhabditis elegans Proc. Natl. Acad. Sci. U. S. A. 99 2002 5854 5859
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 5854-5859
    • Watts, J.L.1    Browse, J.2
  • 28
    • 4344566444 scopus 로고    scopus 로고
    • Cofactor-independent phosphoglycerate mutase has an essential role in Caenorhabditis elegans and is conserved in parasitic nematodes
    • Y. Zhang Cofactor-independent phosphoglycerate mutase has an essential role in Caenorhabditis elegans and is conserved in parasitic nematodes J. Biol. Chem. 279 2004 37185 37190
    • (2004) J. Biol. Chem. , vol.279 , pp. 37185-37190
    • Zhang, Y.1
  • 29
    • 4444290353 scopus 로고    scopus 로고
    • Veterinary anthelmintics: Old and new
    • Q.A. McKellar, and F. Jackson Veterinary anthelmintics: old and new Trends Parasitol. 20 2004 456 461
    • (2004) Trends Parasitol. , vol.20 , pp. 456-461
    • McKellar, Q.A.1    Jackson, F.2
  • 30
    • 9644260489 scopus 로고    scopus 로고
    • A transcriptomic analysis of the phylum Nematoda
    • J. Parkinson A transcriptomic analysis of the phylum Nematoda Nat. Genet. 36 2004 1259 1267
    • (2004) Nat. Genet. , vol.36 , pp. 1259-1267
    • Parkinson, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.