Markers for benzimidazole resistance in human parasitic nematodes?

Parasitology

Volumn 134, Issue 8, 2007, Pages 1087-1092

  Prichard, Roger K ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Albendazole; Benzimidazole anthelmintics; Drug resistance; Human parasitic nematodes; Mebendazole; Resistance markers

Indexed keywords

ALBENDAZOLE; ANTHELMINTIC AGENT; BENZIMIDAZOLE; COMPLEMENTARY DNA; IVERMECTIN; MEBENDAZOLE;

ANTIBIOTIC RESISTANCE; CONFERENCE PAPER; GENETIC MARKER; MOLECULAR GENETICS; NEMATODE; NONHUMAN; PARASITE; PARASITE TRANSMISSION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOIL; STATISTICAL MODEL; WUCHERERIA BANCROFTI;

ANIMALS; ANTHELMINTICS; BENZIMIDAZOLES; DRUG RESISTANCE; GENETIC MARKERS; HUMANS; NEMATODA;

ANIMALIA; NEMATODA; VERMES; WUCHERERIA BANCROFTI;

EID: 34347375089     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S003118200700008X     Document Type: Conference Paper

References (25)

1. Albonico, M., Bickle, Q., Ramsan, M., Montresor, A., Savioli, L. and Taylor, M. (2003). Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar. Bulletin of the World Health Organization 81, 343-352.
2. Albonico, M., Engels, D. and Savioli, L. (2004a). Monitoring drug efficacy and early detection of drug resistance in human soil-transmitted nematodes: a pressing public health agenda for helminth control. International Journal for Parasitology 34, 1205-1210.
3. Albonico, M., Wright, V. and Bickle, Q. (2004b). Molecular analysis of the β-tubulin gene of hookworms as a basis for possible benzimidazole resistance on Pemba Island. Molecular and Biochemical Parasitology 134 281-284.
4. Bennett, A. B., Anderson, T. J. C., Barker, G. C., Michael, E. and Bundy, D. A. P. (2002). Sequence variation in the Trichuris trichiura beta-tubulin locus: implications for the development of benzimidazole resistance. International Journal for Parasitology 32, 1519-1528.
5. Besier, R. B. and Love, S. C. J. (2003). Anthelmintic resistance in sheep nematodes in Australia: the need for new approaches. Australian Journal of Experimental Agriculture 43, 1383-1391.
6. Conway, D. P. (1964). Variance in effectiveness of thiabendazole against Haemonchus contortus in sheep. American Journal of Veterinary Research 25, 844-845.
7. De Clercq, D., Sacko, M., Behnke, J., Gilbert, F., Dorny, P. and Vercruysse, J. (1997). Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali. American Journal of Tropical Medicine and Hygiene 57, 25-30.
8. Duke, B. O. L., Zea-Flores, G., Castro, J., Cupp, E. W. and Munoz, B. (1990). Effects of multiple monthly doses of ivermectin on adult Onchocerca volvulus. American Journal of Tropical Medicine and Hygiene 43, 657-664.
9. Eng, J. K. L., Blackhall, W. J., Osei-Atweneboana, M. Y., Bourguinat, C., Galazzo, D., Beech, R. N., Unnasch, T. R., Awadzi, K., Lubega, G. W. and Prichard, R. K. (2006). Ivermectin selection on β-tubulin: Evidence in Onchocerca volvulus and Haemonchus contortus. Molecular and Biochemical Parasitology 150, 229-235.
10. Eng, J. K. L. and Prichard, R. K. (2005). A comparison of genetic polymorphism in populations of Onchocerca volvulus from untreated- and ivermectin-treated patients. Molecular and Biochemical Parasitology 142, 193-202.
11. Farthing, M. J. G. (2006). Treatment options for the eradication of intestinal protozoa. Nature Clinical Practice Gastroenterology and Hepatology 3, 436-445.
12. Geerts, S. and Gryseels, B. (2001). Anthelmintic resistance in human helminths: a review. Tropical Medicine and International Health 6, 915-921.
13. Hampshire, V. A. (2005). Evaluation of efficacy of heartworm preventive products at the FDA. Veterinary Parasitology 133, 191-195.
14. Horton, J. (2000). Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology 121, S113-S132.
15. Kerboeuf, D., Blackhall, W., Kaminsky, R. and von Samson- Himmelstjerna, G. (2003). P-glycoprotein in helminths: function and perspectives for anthelmintic treatment and reversal of resistance. International Journal of Antimicrobial Agents 22, 332-346.
16. Kotze, A. C., Clifford, S., O'Grady, J., Behnke, J. M. and McCarthy J. S. (2004). An in vitro larval motility assay to determine anthelmintic sensitivity for human hookworm and strongyloides species. American Journal of Tropical Medicine and Hygiene 71 608-616.
17. Michael, E., Malecela-Lazaro, M. N., Simonsen, P. E., Pedersen, E. M., Barker, G., Kumar, A. and Kazura, J. W. (2004). Mathematical modelling and the control of lymphatic filariasis. Lancet Infectious Diseases 4, 223-234.
18. Nare, B., Liu, Z., Prichard, R. K. and Georges, E. (1994). Benzimidazoles, potent antimitotic drugs, are substrates for the P-glycoprotein transporter in multidrug resistant cells. Biochemical Pharmacology 48, 2215-2222.
19. Prichard, R. K. (2001). Genetic variability following selection of Haemonchus contortus with anthelmintics. Trends in Parasitology 17, 445-453.
20. Reynoldson, J. A., Behnke, J. M., Gracey, M., Horton, R. J., Spargo, R., Hopkins, R. M., Constantine, C. C., Gilbert, F., Stead, C., Hobbs, R. P. and Thompson, R. C. (1998). Efficacy of albendazole against Giardia and hookworm in a remote Aboriginal community in the north of Western Australia. Acta Tropica 71, 27-44.
21. Schwab, A. E., Boakye, D., Kyelem, D. and Prichard, R. K. (2005). Detection of benzimidazole-resistance associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection with albendazole and ivermectin treatment. American Journal of Tropical Medicine and Hygiene 73, 234-238.
22. Schwab, A. E., Churcher, T. S., Schwab, A. J., Basáñez, M.-G. and Prichard, R. K. (2006). Population genetics of concurrent selection with albendazole and ivermectin or diethylcarbamazine on the possible spread of albendazole resistance in Wuchereria bancrofti. Parasitology 133, 589-601.
23. Schwab, A. E., Churcher, T. S., Schwab, A. J., Basáñez, M.-G. and Prichard, R. K. (2007). An analysis of the population genetics of potential multi-drug resistance in lymphatic filariasis due to combination chemotherapy. Parasitology, Feb 26:1-16 [Epub ahead of print].
24. Upcroft, J., Mitchell, R., Chen, N. and Upcroft, P. (1996). Albendazole resistance in Giardia is correlated with cytoskeletal changes but not with a mutation at amino acid 200 in beta-tubulin. Microbial Drug Resistance 2, 303-308.
25. Xue, J., Hui-Qing, Q., Jun-Ming, Y., Fujiwara, R., Zhan, B., Hotez, P. and Shu-Hua, X. (2005). Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Experimental Parasitology 111, 219-223.