-
1
-
-
0034090264
-
Hepatocellular carcinoma
-
Okuda K. Hepatocellular carcinoma. J Hepatol 2000; 32: 225-237.
-
(2000)
J Hepatol
, vol.32
, pp. 225-237
-
-
Okuda, K.1
-
3
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
4
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
5
-
-
78751575782
-
The role of microRNAs in liver cancer progression
-
Huang S, He X. The role of microRNAs in liver cancer progression. Br J Cancer 2011; 104: 235-240.
-
(2011)
Br J Cancer
, vol.104
, pp. 235-240
-
-
Huang, S.1
He, X.2
-
6
-
-
77951620660
-
The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma
-
Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, et al. The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J Hepatol 2010; 52: 698-704.
-
(2010)
J Hepatol
, vol.52
, pp. 698-704
-
-
Shimizu, S.1
Takehara, T.2
Hikita, H.3
Kodama, T.4
Miyagi, T.5
Hosui, A.6
-
7
-
-
59149098054
-
MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity
-
Su H, Yang JR, Xu T, Huang J, Xu L, Yuan Y, et al. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res 2009; 69: 1135-1142.
-
(2009)
Cancer Res
, vol.69
, pp. 1135-1142
-
-
Su, H.1
Yang, J.R.2
Xu, T.3
Huang, J.4
Xu, L.5
Yuan, Y.6
-
8
-
-
34447117003
-
Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma
-
Gramantieri L, Ferracin M, Fornari F, Veronese A, Sabbioni S, Liu CG, et al. Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res 2007; 67: 6092-6099.
-
(2007)
Cancer Res
, vol.67
, pp. 6092-6099
-
-
Gramantieri, L.1
Ferracin, M.2
Fornari, F.3
Veronese, A.4
Sabbioni, S.5
Liu, C.G.6
-
9
-
-
77950602604
-
Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
-
Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH, et al. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. HEPATOLOGY 2010; 51: 836-845.
-
(2010)
HEPATOLOGY
, vol.51
, pp. 836-845
-
-
Xiong, Y.1
Fang, J.H.2
Yun, J.P.3
Yang, J.4
Zhang, Y.5
Jia, W.H.6
-
10
-
-
67651154718
-
MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells
-
Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP, Zhuang SM. MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. HEPATOLOGY 2009; 50: 113-121.
-
(2009)
HEPATOLOGY
, vol.50
, pp. 113-121
-
-
Xu, T.1
Zhu, Y.2
Xiong, Y.3
Ge, Y.Y.4
Yun, J.P.5
Zhuang, S.M.6
-
11
-
-
77951491943
-
miR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway
-
Yang F, Yin Y, Wang F, Wang Y, Zhang L, Tang Y, et al. miR-17-5p promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway. HEPATOLOGY 2010; 51: 1614-1616.
-
(2010)
HEPATOLOGY
, vol.51
, pp. 1614-1616
-
-
Yang, F.1
Yin, Y.2
Wang, F.3
Wang, Y.4
Zhang, L.5
Tang, Y.6
-
12
-
-
84984539125
-
MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells
-
Liu WH, Yeh SH, Lu CC, Yu SL, Chen HY, Lin CY, et al. MicroRNA-18a prevents estrogen receptor-alpha expression, promoting proliferation of hepatocellular carcinoma cells. Gastroenterology 2009; 136: 683-693.
-
(2009)
Gastroenterology
, vol.136
, pp. 683-693
-
-
Liu, W.H.1
Yeh, S.H.2
Lu, C.C.3
Yu, S.L.4
Chen, H.Y.5
Lin, C.Y.6
-
13
-
-
69349083676
-
MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality
-
Gramantieri L, Fornari F, Ferracin M, Veronese A, Sabbioni S, Calin GA, et al. MicroRNA-221 targets Bmf in hepatocellular carcinoma and correlates with tumor multifocality. Clin Cancer Res 2009; 15: 5073-5081.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5073-5081
-
-
Gramantieri, L.1
Fornari, F.2
Ferracin, M.3
Veronese, A.4
Sabbioni, S.5
Calin, G.A.6
-
14
-
-
33644853907
-
The colorectal microRNAome
-
Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA, Jr., Sjoblom T, et al. The colorectal microRNAome. Proc Natl Acad Sci U S A 2006; 103: 3687-3692.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3687-3692
-
-
Cummins, J.M.1
He, Y.2
Leary, R.J.3
Pagliarini, R.4
Diaz Jr, L.A.5
Sjoblom, T.6
-
15
-
-
77958487607
-
Computational identification and characterization of primate-specific microRNAs in human genome
-
Lin S, Cheung WK, Chen S, Lu G, Wang Z, Xie D, et al. Computational identification and characterization of primate-specific microRNAs in human genome. Comput Biol Chem 2010; 34: 232-241.
-
(2010)
Comput Biol Chem
, vol.34
, pp. 232-241
-
-
Lin, S.1
Cheung, W.K.2
Chen, S.3
Lu, G.4
Wang, Z.5
Xie, D.6
-
16
-
-
78649403064
-
Proteomic identification of microRNA-122a target proteins in hepatocellular carcinoma
-
Diao S, Zhang JF, Wang H, He ML, Lin MC, Chen Y, et al. Proteomic identification of microRNA-122a target proteins in hepatocellular carcinoma. Proteomics 2010; 10: 3723-3731.
-
(2010)
Proteomics
, vol.10
, pp. 3723-3731
-
-
Diao, S.1
Zhang, J.F.2
Wang, H.3
He, M.L.4
Lin, M.C.5
Chen, Y.6
-
17
-
-
78651411120
-
MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2
-
Lu J, He ML, Wang L, Chen Y, Liu X, Dong Q, et al. MiR-26a inhibits cell growth and tumorigenesis of nasopharyngeal carcinoma through repression of EZH2. Cancer Res 2011; 71: 225-233.
-
(2011)
Cancer Res
, vol.71
, pp. 225-233
-
-
Lu, J.1
He, M.L.2
Wang, L.3
Chen, Y.4
Liu, X.5
Dong, Q.6
-
18
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 2001; 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
19
-
-
28444480969
-
Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells
-
Sekkai D, Gruel G, Herry M, Moucadel V, Constantinescu SN, Albagli O, et al. Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells. Stem Cells 2005; 23: 1634-1642.
-
(2005)
Stem Cells
, vol.23
, pp. 1634-1642
-
-
Sekkai, D.1
Gruel, G.2
Herry, M.3
Moucadel, V.4
Constantinescu, S.N.5
Albagli, O.6
-
20
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
-
Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z, et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell 2009; 15: 283-293.
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
Herrmann, A.2
Deng, J.H.3
Kujawski, M.4
Niu, G.5
Li, Z.6
-
21
-
-
1042302005
-
The STATS of cancer-new molecular targets come of age
-
Yu H, Jove R. The STATS of cancer-new molecular targets come of age. Nat Rev Cancer 2004; 4: 97-105.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
22
-
-
5444237088
-
STAT proteins as novel targets for cancer drug discovery
-
Turkson J. STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets 2004; 8: 409-422.
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 409-422
-
-
Turkson, J.1
-
23
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 2002; 8: 945-954.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
24
-
-
22044437986
-
Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth
-
Corvinus FM, Orth C, Moriggl R, Tsareva SA, Wagner S, Pfitzner EB, et al. Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia 2005; 7: 545-555.
-
(2005)
Neoplasia
, vol.7
, pp. 545-555
-
-
Corvinus, F.M.1
Orth, C.2
Moriggl, R.3
Tsareva, S.A.4
Wagner, S.5
Pfitzner, E.B.6
-
25
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis associated cancer
-
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis associated cancer. Cancer Cell 2009; 15: 103-113.
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
-
26
-
-
0035113393
-
Effectof phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance
-
Feng DY, Zheng H, Tan, Y, Cheng RX. Effectof phosphorylation of MAPK and Stat3 and expression of c-fos and c-jun proteins on hepatocarcinogenesis and their clinical significance. World J Gastroenterol 2001; 7: 33-36.
-
(2001)
World J Gastroenterol
, vol.7
, pp. 33-36
-
-
Feng, D.Y.1
Zheng, H.2
Tan, Y.3
Cheng, R.X.4
-
27
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa H, Matsubara K, Qian G-S, Jackson P, Groopman JD, Manning JE, et al. SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nat Genet 2001; 28: 29-35.
-
(2001)
Nat Genet
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.-S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
-
28
-
-
78449304323
-
Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor
-
Chen Y, Deng J, Fujimoto J, Kadara H, Men T, Lotan D, et al. Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor. Cancer Res 2010; 70: 8917-8926.
-
(2010)
Cancer Res
, vol.70
, pp. 8917-8926
-
-
Chen, Y.1
Deng, J.2
Fujimoto, J.3
Kadara, H.4
Men, T.5
Lotan, D.6
-
29
-
-
58149192454
-
Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but not CCL7 and CCL8, chemokine expression
-
Hintzen C, Haan C, Tuckermann JP, Heinrich PC, Hermanns HM. Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but not CCL7 and CCL8, chemokine expression. J Immunol 2008; 181: 7341-7349.
-
(2008)
J Immunol
, vol.181
, pp. 7341-7349
-
-
Hintzen, C.1
Haan, C.2
Tuckermann, J.P.3
Heinrich, P.C.4
Hermanns, H.M.5
-
30
-
-
0032168152
-
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
-
Heinrich PC, Behrmann I, Müller-Newen G, Schaper F, Graeve L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 1998; 334: 297-314.
-
(1998)
Biochem J
, vol.334
, pp. 297-314
-
-
Heinrich, P.C.1
Behrmann, I.2
Müller-Newen, G.3
Schaper, F.4
Graeve, L.5
-
31
-
-
0028141971
-
Human carcinoma cell lines produce biologically active leukemia inhibitory factor (LIF)
-
Kamohara H, Sakamoto K, Ishiko T, Mita S, Masuda Y, Abe T, et al. Human carcinoma cell lines produce biologically active leukemia inhibitory factor (LIF). Res Commun Mol Pathol Pharmacol 1994; 85: 131-140.
-
(1994)
Res Commun Mol Pathol Pharmacol
, vol.85
, pp. 131-140
-
-
Kamohara, H.1
Sakamoto, K.2
Ishiko, T.3
Mita, S.4
Masuda, Y.5
Abe, T.6
-
32
-
-
0029888789
-
Leukemia-inhibitory factor stimulates breast, kidney, and prostate cancer cell proliferation by paracrine and autocrine pathways
-
Kellokumpu-Lehtinen P, Talpaz M, Harris D, Van Q, Kurzrock R, Estrov Z. Leukemia-inhibitory factor stimulates breast, kidney, and prostate cancer cell proliferation by paracrine and autocrine pathways. Int J Cancer 1996; 66: 515-519.
-
(1996)
Int J Cancer
, vol.66
, pp. 515-519
-
-
Kellokumpu-Lehtinen, P.1
Talpaz, M.2
Harris, D.3
Van, Q.4
Kurzrock, R.5
Estrov, Z.6
-
33
-
-
63249123273
-
TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma
-
Peñuelas S, Anido J, Prieto-Sánchez RM, Folch G, Barba I, Cuartas I, et al. TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma. Cancer Cell 2009; 15: 315-327.
-
(2009)
Cancer Cell
, vol.15
, pp. 315-327
-
-
Peñuelas, S.1
Anido, J.2
Prieto-Sánchez, R.M.3
Folch, G.4
Barba, I.5
Cuartas, I.6
-
34
-
-
77952546785
-
Cytokines, thyroid diseases, and thyroid cancer
-
Lumachi F, Basso SM, Orlando R. Cytokines, thyroid diseases, and thyroid cancer. Cytokine 2010; 50: 229-233.
-
(2010)
Cytokine
, vol.50
, pp. 229-233
-
-
Lumachi, F.1
Basso, S.M.2
Orlando, R.3
-
35
-
-
33947276285
-
Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas
-
Wysoczynski M, Miekus K, Jankowski K, Wanzeck J, Bertolone S, Janowska-Wieczorek A, et al. Leukemia inhibitory factor: a newly identified metastatic factor in rhabdomyosarcomas. Cancer Res 2007; 67: 2131-2140.
-
(2007)
Cancer Res
, vol.67
, pp. 2131-2140
-
-
Wysoczynski, M.1
Miekus, K.2
Jankowski, K.3
Wanzeck, J.4
Bertolone, S.5
Janowska-Wieczorek, A.6
|