Oncostatin M-induced and constitutive activation of the JAK2/STAT5/CIS pathway suppresses CCL1, but Not CCL7 and CCL8, chemokine expression

Journal of Immunology

Volumn 181, Issue 10, 2008, Pages 7341-7349

  Hintzen, Christoph ^a   Haan, Claude ^b   Tuckermann, Jan P ^c   Heinrich, Peter C ^d   Hermanns, Heike M ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF LUXEMBOURG   (Luxembourg)

^c FRITZ LIPMANN INSTITUTE   (Germany)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CCL1 CHEMOKINE; CYTOKINE; CYTOKINE INDUCIBLE SH2 DOMAIN CONTAINING PROTEIN; INTERLEUKIN 1BETA; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; ONCOSTATIN M; PROTEIN C FOS; PROTEIN TYROSINE PHOSPHATASE SHP; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRISTETRAPROLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CHEMOKINE; CYTOKINE INDUCIBLE SH2 CONTAINING PROTEIN; CYTOKINE INDUCIBLE SH2-CONTAINING PROTEIN; JAK2 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; FIBROBLAST; GENE EXPRESSION; GENE LOSS; GENE MUTATION; GENE TARGETING; GENETIC TRANSCRIPTION; HALF LIFE TIME; HUMAN; HUMAN CELL; LYMPHOCYTE MIGRATION; MONOCYTE; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN;

ANIMALS; CELLS, CULTURED; CHEMOKINE CCL1; CHEMOKINE CCL7; CHEMOKINE CCL8; CHEMOKINES; CHEMOTAXIS, LEUKOCYTE; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; JANUS KINASE 2; MICE; ONCOSTATIN M; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN; STAT5 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANSFECTION;

EID: 58149192454     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.10.7341     Document Type: Article

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