Acute and chronically increased immunoreactivity to phosphorylation- independent but not pathological TDP-43 after a single traumatic brain injury in humans

Acta Neuropathologica

Volumn 122, Issue 6, 2011, Pages 715-726

  Johnson, Victoria E ^a,b   Stewart, William ^b,c   Trojanowski, John Q ^d   Smith, Douglas H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

43 kDa transactive response (TAR) DNA binding protein; Alzheimer's disease; DAI; Dementia; Diffuse axonal injury; Head injury; Long term survival; Neurodegeneration; Single versus repetitive TBI; TDP 43; Traumatic brain injury

Indexed keywords

PHOSPHORYLATED TAR DNA BINDING PROTEIN; PHOSPHORYLATION INDEPENDENT TAR DNA BINDING PROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN STEM; CELL INCLUSION; CHILD; CINGULATE GYRUS; CONTROLLED STUDY; CYTOSOL; DISEASE ASSOCIATION; FEMALE; FRONTOTEMPORAL DEMENTIA; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MIDDLE TEMPORAL GYRUS; NERVE DEGENERATION; ONSET AGE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SCHOOL CHILD; SUPERIOR FRONTAL GYRUS; SURVIVAL TIME; TDP 43 PROTEINOPATHY; TRAUMATIC BRAIN INJURY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN INJURIES; BRAIN INJURY, CHRONIC; BRAIN STEM; CASE-CONTROL STUDIES; CHILD; DNA-BINDING PROTEINS; FEMALE; GYRUS CINGULI; HIPPOCAMPUS; HUMANS; MALE; MIDDLE AGED; PHOSPHORYLATION; SURVIVAL RATE; TDP-43 PROTEINOPATHIES; TEMPORAL LOBE; TIME FACTORS; YOUNG ADULT;

EID: 82355191490     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0909-9     Document Type: Article

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