메뉴 건너뛰기




Volumn 7, Issue 1, 2009, Pages 55-66

Focused PCR screen reveals p53 dependence of nitric oxide-induced apoptosis and up-regulation of maspin and plasminogen activator inhibitor-1 in tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

DEATH RECEPTOR 4; FAS ANTIGEN; INTERLEUKIN 1BETA CONVERTING ENZYME; MASPIN; MESSENGER RNA; NITRIC OXIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BCL 2; PROTEIN BIK; PROTEIN P53; PUMA PROTEIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 58649124330     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-08-0331     Document Type: Article
Times cited : (15)

References (60)
  • 1
    • 4243131409 scopus 로고    scopus 로고
    • Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation
    • Contestabile A, Ciani E. Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation. Neurochem Int 2004;45:903 -14.
    • (2004) Neurochem Int , vol.45 , pp. 903-914
    • Contestabile, A.1    Ciani, E.2
  • 2
    • 0142242181 scopus 로고    scopus 로고
    • Nitric oxide activates diverse signaling pathways to regulate gene expression
    • Hemish J, Nakaya N, Mittal V, Enikolopov G. Nitric oxide activates diverse signaling pathways to regulate gene expression. J Biol Chem 2003; 278:42321 -9.
    • (2003) J Biol Chem , vol.278 , pp. 42321-42329
    • Hemish, J.1    Nakaya, N.2    Mittal, V.3    Enikolopov, G.4
  • 4
    • 21744449943 scopus 로고    scopus 로고
    • Nitric oxide as a modulator of apoptosis
    • Li CQ, Wogan GN. Nitric oxide as a modulator of apoptosis. Cancer Lett 2005;226:1 -15.
    • (2005) Cancer Lett , vol.226 , pp. 1-15
    • Li, C.Q.1    Wogan, G.N.2
  • 5
    • 22144444152 scopus 로고    scopus 로고
    • A central role for S-nitrosylation in apoptosis
    • Benhar M, Stamler JS. A central role for S-nitrosylation in apoptosis. Nat Cell Biol 2005;7:645-6.
    • (2005) Nat Cell Biol , vol.7 , pp. 645-646
    • Benhar, M.1    Stamler, J.S.2
  • 6
    • 0042665423 scopus 로고    scopus 로고
    • Nitric oxide: NO apoptosis or turning it ON?
    • Brune B. Nitric oxide: NO apoptosis or turning it ON? Cell Death Differ 2003; 10:864-9.
    • (2003) Cell Death Differ , vol.10 , pp. 864-869
    • Brune, B.1
  • 7
    • 0036315365 scopus 로고    scopus 로고
    • Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140
    • Feng Z, Li L, Ng PY, Porter AG. Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140. Mol Cell Biol 2002;22:5357-66.
    • (2002) Mol Cell Biol , vol.22 , pp. 5357-5366
    • Feng, Z.1    Li, L.2    Ng, P.Y.3    Porter, A.G.4
  • 8
    • 1042266671 scopus 로고    scopus 로고
    • JNK-dependent phosphorylation ofc-Jun on serine 63 mediates nitric oxide-induced apoptosis ofneuroblastoma cells
    • Li L, Feng Z, Porter AG. JNK-dependent phosphorylation ofc-Jun on serine 63 mediates nitric oxide-induced apoptosis ofneuroblastoma cells. J Biol Chem 2004;279:4058-65.
    • (2004) J Biol Chem , vol.279 , pp. 4058-4065
    • Li, L.1    Feng, Z.2    Porter, A.G.3
  • 9
    • 0038273373 scopus 로고    scopus 로고
    • Ciani E, Guidi S, Della VG, Perini G, Bartesaghi R, Contestabile A. Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation. J Biol Chem 002;277:49896-902.
    • Ciani E, Guidi S, Della VG, Perini G, Bartesaghi R, Contestabile A. Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation. J Biol Chem 002;277:49896-902.
  • 10
    • 2442535969 scopus 로고    scopus 로고
    • Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells
    • Dhakshinamoorthy S, Porter AG. Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells. J Biol Chem 2004;279: 20096-107.
    • (2004) J Biol Chem , vol.279 , pp. 20096-20107
    • Dhakshinamoorthy, S.1    Porter, A.G.2
  • 11
    • 34548769262 scopus 로고    scopus 로고
    • Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some ofwhich govern neuroblastoma cell viability
    • Dhakshinamoorthy S, Sridharan SR, Li L, Ng PY, Boxer LM, Porter AG. Protein/DNA arrays identify nitric oxide-regulated cis-element and trans-factor activities some ofwhich govern neuroblastoma cell viability. Nucleic Acids Res 2007;35:5439-51.
    • (2007) Nucleic Acids Res , vol.35 , pp. 5439-5451
    • Dhakshinamoorthy, S.1    Sridharan, S.R.2    Li, L.3    Ng, P.Y.4    Boxer, L.M.5    Porter, A.G.6
  • 12
    • 22144477159 scopus 로고    scopus 로고
    • S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding
    • Hara MR, Agrawal N, Kim SF, et al. S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 binding. Nat Cell Biol 2005;7:665-74.
    • (2005) Nat Cell Biol , vol.7 , pp. 665-674
    • Hara, M.R.1    Agrawal, N.2    Kim, S.F.3
  • 13
    • 33747790881 scopus 로고    scopus 로고
    • Specific contribution of p19(ARF) to nitric oxide-dependent apoptosis
    • Zeini M, Traves PG, Lopez-Fontal R, et al. Specific contribution of p19(ARF) to nitric oxide-dependent apoptosis. J Immunol 2006;177:3327-36.
    • (2006) J Immunol , vol.177 , pp. 3327-3336
    • Zeini, M.1    Traves, P.G.2    Lopez-Fontal, R.3
  • 14
    • 0034710303 scopus 로고    scopus 로고
    • p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons
    • Ghatan S, Larner S, Kinoshita Y, et al. p38 MAP kinase mediates bax translocation in nitric oxide-induced apoptosis in neurons. J Cell Biol 2000;150: 335-47.
    • (2000) J Cell Biol , vol.150 , pp. 335-347
    • Ghatan, S.1    Larner, S.2    Kinoshita, Y.3
  • 15
    • 0038359369 scopus 로고    scopus 로고
    • Nitric oxide induces phosphorylation of p53 and impairs nuclear export
    • Schneiderhan N, Budde A, Zhang Y, Brune B. Nitric oxide induces phosphorylation of p53 and impairs nuclear export. Oncogene 2003;22:2857 -68.
    • (2003) Oncogene , vol.22 , pp. 2857-2868
    • Schneiderhan, N.1    Budde, A.2    Zhang, Y.3    Brune, B.4
  • 16
    • 0038188668 scopus 로고    scopus 로고
    • Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation
    • Wang X, Zalcenstein A, Oren M. Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation. Cell Death Differ 2003;10:468-76.
    • (2003) Cell Death Differ , vol.10 , pp. 468-476
    • Wang, X.1    Zalcenstein, A.2    Oren, M.3
  • 17
    • 22244454400 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in lympho- blastoid and fibroblast cells dependent on the phosphorylation and activation of p53
    • McLaughlin LM, Demple B. Nitric oxide-induced apoptosis in lympho- blastoid and fibroblast cells dependent on the phosphorylation and activation of p53. Cancer Res 2005;65:6097-104.
    • (2005) Cancer Res , vol.65 , pp. 6097-6104
    • McLaughlin, L.M.1    Demple, B.2
  • 18
    • 0037031848 scopus 로고    scopus 로고
    • p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NF&kappa B-dependent transcription and stabilization by serine 15 phosphorylation
    • Kim SJ, Hwang SG, Shin DY, Kang SS, Chun JS. p38 kinase regulates nitric oxide-induced apoptosis of articular chondrocytes by accumulating p53 via NF&kappa B-dependent transcription and stabilization by serine 15 phosphorylation. J Biol Chem 2002;277:33501 -8.
    • (2002) J Biol Chem , vol.277 , pp. 33501-33508
    • Kim, S.J.1    Hwang, S.G.2    Shin, D.Y.3    Kang, S.S.4    Chun, J.S.5
  • 19
    • 27744587916 scopus 로고    scopus 로고
    • cGMP-independent nitric oxide signaling and regulation of the cell cycle
    • Cui X, Zhang J, Ma P, et al. cGMP-independent nitric oxide signaling and regulation of the cell cycle. BMC Genomics 2005;6:151.
    • (2005) BMC Genomics , vol.6 , pp. 151
    • Cui, X.1    Zhang, J.2    Ma, P.3
  • 20
    • 2342583373 scopus 로고    scopus 로고
    • Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53
    • Li CQ, Robles AI, Hanigan CL, et al. Apoptotic signaling pathways induced by nitric oxide in human lymphoblastoid cells expressing wild-type or mutant p53. Cancer Res 2004;64:3022-9.
    • (2004) Cancer Res , vol.64 , pp. 3022-3029
    • Li, C.Q.1    Robles, A.I.2    Hanigan, C.L.3
  • 21
    • 33845270990 scopus 로고    scopus 로고
    • Regulating the p53 pathway: In vitro hypotheses, in vivo veritas
    • Toledo F, Wahl GM. Regulating the p53 pathway: in vitro hypotheses, in vivo veritas. Nat Rev Cancer 2006;6:909-23.
    • (2006) Nat Rev Cancer , vol.6 , pp. 909-923
    • Toledo, F.1    Wahl, G.M.2
  • 25
    • 33845496093 scopus 로고    scopus 로고
    • Rozan LM, El Deiry WS. p53 downstream target genes and tumor suppression: a classical view in evolution. Cell Death Differ2007;14:3-9.
    • Rozan LM, El Deiry WS. p53 downstream target genes and tumor suppression: a classical view in evolution. Cell Death Differ2007;14:3-9.
  • 27
    • 18144416611 scopus 로고    scopus 로고
    • The transcriptional targets of p53 in apoptosis control
    • Yu J, Zhang L. The transcriptional targets of p53 in apoptosis control. Biochem Biophys Res Commun 2005;331:851 -8.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 851-858
    • Yu, J.1    Zhang, L.2
  • 28
    • 44049095767 scopus 로고    scopus 로고
    • In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
    • Michalak EM, Villunger A, Adams JM, Strasser A. In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute. Cell Death Differ 2008;15:1019-29.
    • (2008) Cell Death Differ , vol.15 , pp. 1019-1029
    • Michalak, E.M.1    Villunger, A.2    Adams, J.M.3    Strasser, A.4
  • 29
    • 0035953394 scopus 로고    scopus 로고
    • DNA microarrays identification of primary and secondary target genes regulated by p53
    • Kannan K, Amariglio N, Rechavi G, et al. DNA microarrays identification of primary and secondary target genes regulated by p53. Oncogene 2001;20: 2225-34.
    • (2001) Oncogene , vol.20 , pp. 2225-2234
    • Kannan, K.1    Amariglio, N.2    Rechavi, G.3
  • 30
    • 2442655506 scopus 로고    scopus 로고
    • p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis
    • Kho PS, Wang Z, Zhuang L, et al. p53-regulated transcriptional program associated with genotoxic stress-induced apoptosis. J Biol Chem 2004;279: 21183-92.
    • (2004) J Biol Chem , vol.279 , pp. 21183-21192
    • Kho, P.S.1    Wang, Z.2    Zhuang, L.3
  • 31
    • 20444475777 scopus 로고    scopus 로고
    • A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network
    • Miled C, Pontoglio M, Garbay S, Yaniv M, Weitzman JB. A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network. Cancer Res 2005;65:5096-104.
    • (2005) Cancer Res , vol.65 , pp. 5096-5104
    • Miled, C.1    Pontoglio, M.2    Garbay, S.3    Yaniv, M.4    Weitzman, J.B.5
  • 32
    • 12444252198 scopus 로고    scopus 로고
    • Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
    • Mirza A, Wu Q, Wang L, et al. Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression. Oncogene 2003; 22:3645-54.
    • (2003) Oncogene , vol.22 , pp. 3645-3654
    • Mirza, A.1    Wu, Q.2    Wang, L.3
  • 33
    • 30344478870 scopus 로고    scopus 로고
    • A global map of p53 transcription-factor binding sites in the human genome
    • Wei CL, Wu Q, Vega VB, et al. A global map of p53 transcription-factor binding sites in the human genome. Cell 2006;124:207-19.
    • (2006) Cell , vol.124 , pp. 207-219
    • Wei, C.L.1    Wu, Q.2    Vega, V.B.3
  • 35
    • 0029812216 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis: P53-dependent and p53-independent signalling pathways
    • Messmer UK, Brune B. Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. Biochem J 1996;319:299-305.
    • (1996) Biochem J , vol.319 , pp. 299-305
    • Messmer, U.K.1    Brune, B.2
  • 36
    • 0035827335 scopus 로고    scopus 로고
    • A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation
    • Zhang Y, Xiong Y. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation. Science 2001;292:1910-5.
    • (2001) Science , vol.292 , pp. 1910-1915
    • Zhang, Y.1    Xiong, Y.2
  • 38
    • 0034656243 scopus 로고    scopus 로고
    • Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
    • Zhao R, Gish K, Murphy M, et al. Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev 2000;14:981-93.
    • (2000) Genes Dev , vol.14 , pp. 981-993
    • Zhao, R.1    Gish, K.2    Murphy, M.3
  • 40
    • 33845418951 scopus 로고    scopus 로고
    • Senescence, wound healing and cancer: The PAI-1 connection
    • Kortlever RM, Bernards R. Senescence, wound healing and cancer: the PAI-1 connection. Cell Cycle 2006;5:2697-703.
    • (2006) Cell Cycle , vol.5 , pp. 2697-2703
    • Kortlever, R.M.1    Bernards, R.2
  • 41
    • 35348834104 scopus 로고    scopus 로고
    • PAI-1 - a potential therapeutic target in cancer
    • Andreasen PA. PAI-1 - a potential therapeutic target in cancer. Curr Drug Targets 2007;8:1030-41.
    • (2007) Curr Drug Targets , vol.8 , pp. 1030-1041
    • Andreasen, P.A.1
  • 42
    • 0034096190 scopus 로고    scopus 로고
    • p53 regulates the expression of the tumor suppressor gene maspin
    • Zou Z, Gao C, Nagaich AK, et al. p53 regulates the expression of the tumor suppressor gene maspin. J Biol Chem 2000;275:6051 -4.
    • (2000) J Biol Chem , vol.275 , pp. 6051-6054
    • Zou, Z.1    Gao, C.2    Nagaich, A.K.3
  • 43
    • 33746616991 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence
    • Kortlever RM, Higgins PJ, Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 2006;8:877-84.
    • (2006) Nat Cell Biol , vol.8 , pp. 877-884
    • Kortlever, R.M.1    Higgins, P.J.2    Bernards, R.3
  • 44
    • 0026446686 scopus 로고
    • Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
    • Shaulian E, Zauberman A, Ginsberg D, Oren M. Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol Cell Biol 1992;12:5581-92.
    • (1992) Mol Cell Biol , vol.12 , pp. 5581-5592
    • Shaulian, E.1    Zauberman, A.2    Ginsberg, D.3    Oren, M.4
  • 45
    • 46649101876 scopus 로고    scopus 로고
    • Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
    • Sen N, Hara MR, Kornberg MD, et al. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nat Cell Biol 2008;10:866-73.
    • (2008) Nat Cell Biol , vol.10 , pp. 866-873
    • Sen, N.1    Hara, M.R.2    Kornberg, M.D.3
  • 46
    • 30344450087 scopus 로고    scopus 로고
    • Up-regulation of Bak and Bim via JNK downstream pathway in the response to nitric oxide in human glioblastoma cells
    • Jin HO, Park IC, An S, et al. Up-regulation of Bak and Bim via JNK downstream pathway in the response to nitric oxide in human glioblastoma cells. J Cell Physiol 2006;206:477-86.
    • (2006) J Cell Physiol , vol.206 , pp. 477-486
    • Jin, H.O.1    Park, I.C.2    An, S.3
  • 47
    • 0037059796 scopus 로고    scopus 로고
    • ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status
    • Kim SJ, Ju JW, Oh CD, et al. ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status. J Biol Chem 2002;277:1332-9.
    • (2002) J Biol Chem , vol.277 , pp. 1332-1339
    • Kim, S.J.1    Ju, J.W.2    Oh, C.D.3
  • 48
    • 0035815646 scopus 로고    scopus 로고
    • Direct transcriptional activation of human caspase-1 by tumor suppressorp53
    • Gupta S, Radha V, Furukawa Y, Swarup G. Direct transcriptional activation of human caspase-1 by tumor suppressorp53. J Biol Chem 2001;276:10585-8.
    • (2001) J Biol Chem , vol.276 , pp. 10585-10588
    • Gupta, S.1    Radha, V.2    Furukawa, Y.3    Swarup, G.4
  • 49
    • 0029144441 scopus 로고
    • Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53
    • Kunz C, Pebler S, Otte J, von der AD. Differential regulation of plasminogen activator and inhibitor gene transcription by the tumor suppressor p53. Nucleic Acids Res 1995;23:3710-7.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3710-3717
    • Kunz, C.1    Pebler, S.2    Otte, J.3    von der, A.D.4
  • 50
    • 34548031870 scopus 로고    scopus 로고
    • The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
    • Fernandes-Alnemri T, Wu J, Yu JW, et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ 2007;14:1590-604.
    • (2007) Cell Death Differ , vol.14 , pp. 1590-1604
    • Fernandes-Alnemri, T.1    Wu, J.2    Yu, J.W.3
  • 51
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
    • Mariathasan S, Monack DM. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 2007; 7:31 -40.
    • (2007) Nat Rev Immunol , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 52
    • 0037406847 scopus 로고    scopus 로고
    • Nitric oxide regulation of maspin expression in normal mammary epithelial and breast cancer cells
    • Khalkhali-Ellis Z, Hendrix MJ. Nitric oxide regulation of maspin expression in normal mammary epithelial and breast cancer cells. Am J Pathol 2003;162: 1411 -7.
    • (2003) Am J Pathol , vol.162 , pp. 1411-1417
    • Khalkhali-Ellis, Z.1    Hendrix, M.J.2
  • 53
    • 3242690522 scopus 로고    scopus 로고
    • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
    • Erster S, Mihara M, Kim RH, Petrenko O, Moll UM. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 2004;24: 6728 -41.
    • (2004) Mol Cell Biol , vol.24 , pp. 6728-6741
    • Erster, S.1    Mihara, M.2    Kim, R.H.3    Petrenko, O.4    Moll, U.M.5
  • 54
    • 0037349289 scopus 로고    scopus 로고
    • p53 has a direct apoptogenic role at the mitochondria
    • Mihara M, Erster S, Zaika A, et al. p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003;11:577-90.
    • (2003) Mol Cell , vol.11 , pp. 577-590
    • Mihara, M.1    Erster, S.2    Zaika, A.3
  • 55
    • 0028208912 scopus 로고
    • Maspin, a serpin with tumor- suppressing activity in human mammary epithelial cells
    • Zou Z, Anisowicz A, Hendrix MJ, et al. Maspin, a serpin with tumor- suppressing activity in human mammary epithelial cells. Science 1994;263: 526-9.
    • (1994) Science , vol.263 , pp. 526-529
    • Zou, Z.1    Anisowicz, A.2    Hendrix, M.J.3
  • 56
    • 0037071891 scopus 로고    scopus 로고
    • Maspin sensitizes breast carcinoma cells to induced apoptosis
    • Jiang N, Meng Y, Zhang S, Mensah-Osman E, Sheng S. Maspin sensitizes breast carcinoma cells to induced apoptosis. Oncogene 2002;21:4089-98.
    • (2002) Oncogene , vol.21 , pp. 4089-4098
    • Jiang, N.1    Meng, Y.2    Zhang, S.3    Mensah-Osman, E.4    Sheng, S.5
  • 57
    • 1642274517 scopus 로고    scopus 로고
    • Bax mediates the apoptosis- sensitizing effect of maspin
    • Liu J, Yin S, Reddy N, Spencer C, Sheng S. Bax mediates the apoptosis- sensitizing effect of maspin. Cancer Res 2004;64:1703 -11.
    • (2004) Cancer Res , vol.64 , pp. 1703-1711
    • Liu, J.1    Yin, S.2    Reddy, N.3    Spencer, C.4    Sheng, S.5
  • 58
    • 24044518203 scopus 로고    scopus 로고
    • Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis
    • Tahmatzopoulos A, Sheng S, Kyprianou N. Maspin sensitizes prostate cancer cells to doxazosin-induced apoptosis. Oncogene 2005;24:5375 -83.
    • (2005) Oncogene , vol.24 , pp. 5375-5383
    • Tahmatzopoulos, A.1    Sheng, S.2    Kyprianou, N.3
  • 59
    • 33747347557 scopus 로고    scopus 로고
    • A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells
    • Balsara RD, Castellino FJ, Ploplis VA. A novel function of plasminogen activator inhibitor-1 in modulation of the AKT pathway in wild-type and plasminogen activator inhibitor-1-deficient endothelial cells. J Biol Chem 2006; 281:22527-36.
    • (2006) J Biol Chem , vol.281 , pp. 22527-22536
    • Balsara, R.D.1    Castellino, F.J.2    Ploplis, V.A.3
  • 60
    • 10744222414 scopus 로고    scopus 로고
    • Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1- deficient mice
    • Ploplis VA, Balsara R, Sandoval-Cooper MJ, et al. Enhanced in vitro proliferation of aortic endothelial cells from plasminogen activator inhibitor-1- deficient mice. J Biol Chem 2004;279:6143-51.
    • (2004) J Biol Chem , vol.279 , pp. 6143-6151
    • Ploplis, V.A.1    Balsara, R.2    Sandoval-Cooper, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.