Nitric oxide contributes to adriamycin's antitumor effect

Journal of Surgical Research

Volumn 69, Issue 2, 1997, Pages 283-287

  Lind, D Scott ^a   Kontaridis, Maria I ^a   Edwards, Paul D ^a   Josephs, Michael D ^a   Moldawer, Lyle L ^a   Copeland III, Edward M ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; DOXORUBICIN; GAMMA INTERFERON; INTERLEUKIN 1; NITRIC OXIDE; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; NITROGEN METABOLISM; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031148313     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsre.1997.5015     Document Type: Conference Paper

References (27)

1. 1. Hudis, C. A., and Norton, L. Systemic adjuvant treatment of breast cancer. Curr. Opin. Oncol. 5: 982-990, 1993.
2. 2. Son, K., and Kim, Y. M. In vivo cisplatin-exposed macrophages increase immunostimulant-induced nitric oxide synthesis for tumor cell killing. Cancer Res. 55: 5524-5527, 1995.
3. 3. Pacelli, R., Taira, J., Cook, J. A., Wink, D. A., and Krishna, M. C. Hydroxyurea reacts with heme proteins to generate nitric oxide. Lancet 347: 900, 1996.
4. 4. Bani, D., Masini, E., Bello, M. G., Bigazzi, M., and Sacchi, T. B. Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells. Cancer Res. 55: 5272-5275, 1995.
5. 5. Marangos, C. M., Wang, J. M., and Hrabie, J. A. et al. Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cell via nitric oxide release. Cancer Res. 53: 564-568, 1993.
6. 6. Kitajima, I., Kawahara, K., and Nakajima, T. et al. Nitric oxide mediated apoptosis in murine mastocytoma. Biochem. Biophys. Res. Commun. 204: 244-251, 1994.
7. 7. Magrinat, G., Mason, S. N., Shami, P. J., and Weinberg, J. B. Nitric oxide modulation of human leukemic cell differentiation and gene expression. Blood 80: 1880-1884, 1992.
8. 8. Dong, Z., Staroselsky, A., Qi, X., Xie, K., and Fidler, I. J. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells. Cancer Res. 54: 789-793, 1994.
9. 9. DiNapoli, M. R., Calderon, C. L., and Lopez, D. M. The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduced expression of the inducible nitric oxide gene. J. Exp. Med. 183: 1323-1329, 1996.
10. 15N]nitrate in biological fluids. Anal. Biochem. 126: 131-136, 1982.
11. 11. Mosmann, T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods 65: 55-63, 1983.
12. 12. Ravdin, P. M. Anthracycline resistance in breast cancer: Clinical application of current knowledge. Eur. J. Cancer 31 A: S11-S14, 1995.
13. 13. Knowles, R. G., and Moncada, S. Nitric oxide synthase in mammals. Biochem. J. 298: 249-258, 1994.
14. 14. Cendan, J. C., Topping, D. B., Pruitt, J., Snowdy, S., Copeland, E. M., III, and Lind, D. S. Inflammatory mediators stimulate arginine transport and arginine-derived nitric oxide production in a murine breast cancer cell line. J. Surg. Res. 60: 284-288, 1996.
15. 15. Cendan, J. C., Copeland, E. M., III, Souba, W. W., and Lind, D. S. Cytokines regulate endotoxin stimulation of arginine transport. Surgery 117: 213-219, 1995.
16. 16. Wang, Q., Redovan, C., and Tubbs, et al. Selective cytokine expression in renal carcinoma tumor cells. Int. J. Cancer 61: 780-785, 1995.
17. 17. Kreuser, E. D., Wadler, S., and Thiel, E. Biochemical modulation of cytotoxic drugs by cytokines: Molecular mechanisms in experimental oncology. Recent Results Cancer Res. 139: 371-382, 1995.
18. 18. Joshi, P., Vig, P. J. S., Veerisetty, V., Cameron, J. A., Sekhon, B. S., and Desaiah, D. Increase in brain nitric oxide synthase activity in daunorubicin-treated rats. Pharmacol. Toxicol. 78: 99-103, 1996.
19. 19. Park, C. S., Park, R., and Krishna, G. Constitutive expression and structural diversity of inducible isoform of nitric oxide synthase in human tissues. Life Sci. 59: 219-225, 1996.
20. 20. Manthey, C. L., Perera, P. Y., Balkowski, C. A., and Vogel, S. N. Taxol provides a second signal for murine macrophage tumoricidal activity. J. Immunol. 152: 825-831, 1994.
21. 21. Green, D. R., Bissonnette, R. P., and Cotter, T. G. Apoptosis and cancer. Principles Practice Oncol. Updates 8(1): 1-14, 1995.
22. 22. Geng, Y., Hellstrand, K., Wennmalm, A., and Hansson, G. K. Apoptotic death of human leukemic cells induced by vascular cells expressing nitric oxide synthase in response to γ interferon and tumor necrosis factor α. Cancer Res. 56: 866-874, 1996.
23. 23. Cui, S., Reichner, J. S., Mateo, R. B., and Albina, J. Activated macrophages induce apoptosis in tumor cells through nitric oxide-dependent or -independent mechanisms. Cancer Res. 54: 2462-2467, 1994.
24. 24. Brune, B., Messner, U. K., and Sandua, K. The role of nitric oxide in cell injury. Toxicol. Lett. 82: 233-237, 1995.
25. 25. Stuehr, D. J., and Nathan, C. F. Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor targets. J. Exp. Med. 169: 1543-1548, 1989.
26. 26. Kwon, N. S., Stuehr, D. J., and Nathan, C. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide. J. Exp. Med. 174: 761-767, 1991.
27. 27. Noronha-Dutra, A. A., Epperlein, M. M., and Woolf, N. Reaction of nitric oxide with hydrogen peroxide to produce potentially cytotoxic singlet oxygen as a model for nitric oxide-mediated killing. FEBS Lett. 321: 59-62, 1993.