Investigation of in vivo diferric tyrosyl radical formation in Saccharomyces cerevisiae Rnr2 protein: Requirement of Rnr4 and contribution of Grx3/4 and Dre2 proteins

Journal of Biological Chemistry

Volumn 286, Issue 48, 2011, Pages 41499-41509

  Zhang, Yan ^a   Liu, Lili ^b   Wu, Xiaorong ^b   An, Xiuxiang ^b   Stubbe, JoAnne ^a   Huang, Mingxia ^b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COFACTORS; CYTOSOLIC; GENETIC BACKGROUNDS; GROWTH DEFECTS; HETERODIMERS; HYDROXYUREA; IN-VIVO; IRON BINDING; IRON CHELATORS; IRON DEPLETION; IRON LOADING; LOW LEVEL; MONOTHIOL; RIBONUCLEOTIDE REDUCTASE; SPHEROPLASTS; TYROSYL RADICALS;

LOADING; PROTEINS; YEAST;

IRON;

DIFFERIC TYROSYL RADICAL; DRE2 PROTEIN; GLUTAREDOXIN; GLUTAREDOXIN 3; GLUTAREDOXIN 4; HYDROXYUREA; IRON; IRON CHELATING AGENT; IRON SULFUR PROTEIN; RADICAL; RIBONUCLEOTIDE REDUCTASE; RIBONUCLEOTIDE REDUCTASE 2; RIBONUCLEOTIDE REDUCTASE 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BETA CHAIN; CELL GROWTH; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; IN VIVO STUDY; IRON DEPLETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; SPHEROPLAST;

GLUTAREDOXINS; HYDROXYUREA; IRON; IRON-SULFUR PROTEINS; MUTATION; OXIDOREDUCTASES; RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPHEROPLASTS; TYROSINE;

EID: 82355184470     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.294074     Document Type: Article

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