Anamorsin Is a [2Fe-2S] cluster-containing substrate of the Mia40-dependent mitochondrial protein trapping machinery

Chemistry and Biology

Volumn 18, Issue 6, 2011, Pages 794-804

  Banci, Lucia ^a   Bertini, Ivano ^a   Ciofi Baffoni, Simone ^a   Boscaro, Francesca ^a   Chatzi, Afroditi ^b,c   Mikolajczyk, MacIej ^a   Tokatlidis, Kostas ^b,c   Winkelmann, Julia ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^c UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CIAPIN1 PROTEIN, HUMAN; CYSTEINE; DRE2 PROTEIN, S CEREVISIAE; IRON; IRON SULFUR PROTEIN; MIA40 PROTEIN, HUMAN; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE; SULFUR;

ARTICLE; CHEMISTRY; ENZYME SPECIFICITY; HUMAN; METABOLISM; MITOCHONDRION; OXIDATION REDUCTION REACTION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

CYSTEINE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRON; IRON-SULFUR PROTEINS; MITOCHONDRIA; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; SULFUR;

EID: 79959522180     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2011.03.015     Document Type: Article

References (48)

1. C. Andreini, L. Banci, I. Bertini, S. Elmi, and A. Rosato Non-heme iron through the three domains of life Proteins 67 2007 317 324 (Pubitemid 46449409)
2. C. Andreini, I. Bertini, G. Cavallaro, R.J. Najmanovich, and J.M. Thornton Structural analysis of metal sites in proteins: non-heme iron sites as a case study J. Mol. Biol. 388 2009 356 380
3. 2 proteins as an example Struct. Bond. 72 1990 113 135
4. L. Banci, I. Bertini, S. Ciofi-Baffoni, A. Janicka, M. Martinelli, H. Kozlowski, and P. Palumaa A structural-dynamical characterization of human Cox17 J. Biol. Chem. 283 2008 7912 7920
5. L. Banci, I. Bertini, C. Cefaro, S. Ciofi-Baffoni, A. Gallo, M. Martinelli, D.P. Sideris, N. Katrakili, and K. Tokatlidis MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria Nat. Struct. Mol. Biol. 16 2009 198 206
6. L. Banci, I. Bertini, C. Cefaro, L. Cenacchi, S. Ciofi-Baffoni, I.C. Felli, A. Gallo, L. Gonnelli, E. Luchinat, and D. Sideris Molecular chaperone function of Mia40 triggers consecutive induced folding steps of the substrate in mitochondrial protein import Proc. Natl. Acad. Sci. USA 107 2010 20190 20195
7. I. Bertini, P. Turano, and A.J. Vila Nuclear magnetic resonance of paramagnetic metalloproteins Chem. Rev. 93 1993 2833 2932
8. I. Bertini, S. Ciurli, and C. Luchinat The electronic structure of FeS centers in proteins and models. A contribution to the understanding of their electron transfer properties Struct. Bond. 83 1995 1 53
9. I. Bertini, C. Luchinat, A. Provenzani, A. Rosato, and P.R. Vasos Browsing gene banks for Fe2S2 ferredoxins and structural modeling of 88 plant-type sequences: an analysis of fold and function Proteins 46 2002 110 127 (Pubitemid 34033581)
10. I. Bertini, J.A. Cowan, C. Del Bianco, C. Luchinat, and S.S. Mansy Thermotoga maritima IscU. Structural characterization and dynamics of a new class of metallochaperone J. Mol. Biol. 331 2003 907 924 (Pubitemid 36945444)
11. P. Cavadini, G. Biasiotto, M. Poli, S. Levi, R. Verardi, I. Zanella, M. Derosas, R. Ingrassia, M. Corrado, and P. Arosio RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload Blood 109 2007 3552 3559 (Pubitemid 46572549)
12. V.C. Culotta, M. Yang, and T.V. O'Halloran Activation of superoxide dismutases: putting the metal to the pedal Biochim. Biophys. Acta 1763 2006 747 758 (Pubitemid 44189546)
13. K. Gabriel, D. Milenkovic, A. Chacinska, J. Muller, B. Guiard, N. Pfanner, and C. Meisinger Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway J. Mol. Biol. 365 2007 612 620 (Pubitemid 44960363)
14. Z. Hao, X. Li, T. Qiao, J. Zhang, X. Shao, and D. Fan Distribution of CIAPIN1 in normal fetal and adult human tissues J. Histochem. Cytochem. 54 2006 417 426
15. J.M. Herrmann, and J. Riemer The intermembrane space of mitochondria Antioxid. Redox Signal. 13 2010 1341 1358
16. T. Inubushi, and E.D. Becker Efficient detection of paramagnetically shifted NMR resonances by optimizing the WEFT pulse sequence J. Magn. Reson. 51 1983 128 133
17. R.M. Kagan, and S. Clarke Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes Arch. Biochem. Biophys. 310 1994 417 427
18. H. Kawamata, and G. Manfredi Import, maturation, and function of SOD1 and its copper chaperone CCS in the mitochondrial intermembrane space Antioxid. Redox Signal. 13 2010 1375 1384
19. R. Keller The Computer Aided Resonance Assignment Tutorial 2004 CANTINA Verlag Goldau
20. J.H. Kim, A.K. Fuzery, M. Tonelli, D.T. Ta, W.M. Westler, L.E. Vickery, and J.L. Markley Structure and dynamics of the iron-sulfur cluster assembly scaffold protein IscU and its interaction with the cochaperone HscB Biochemistry 48 2009 6062 6071
21. G. Kispal, P. Csere, C. Prohl, and R. Lill The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins EMBO J. 18 1999 3981 3989 (Pubitemid 29335851)
22. G. Kuhnke, K. Neumann, U. Mühlenhoff, and R. Lill Stimulation of the ATPase activity of the yeast mitochondrial ABC transporter Atm1p by thiol compounds Mol. Membr. Biol. 23 2006 173 184 (Pubitemid 43786019)
23. H. Lange, T. Lisowsky, J. Gerber, U. Mühlenhoff, G. Kispal, and R. Lill An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins EMBO Rep. 2 2001 715 720 (Pubitemid 32798715)
24. X. Li, K. Wu, and D. Fan CIAPIN1 as a therapeutic target in cancer Expert Opin. Ther. Targets 14 2010 603 610
25. R. Lill Function and biogenesis of iron-sulphur proteins Nature 460 2009 831 838
26. R. Lill, and U. Mühlenhoff Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms Annu. Rev. Cell Dev. Biol. 22 2006 457 486
27. R. Lill, and U. Mühlenhoff Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases Annu. Rev. Biochem. 77 2008 669 700
28. Y. Liu, and J.A. Cowan Iron-sulfur cluster biosynthesis: characterization of a molten globule domain in human NFU Biochemistry 48 2009 7512 7518
29. P. Luciano, S. Vial, M.A. Vergnolle, S.D. Dyall, D.R. Robinson, and K. Tokatlidis Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex EMBO J. 20 2001 4099 4106 (Pubitemid 32751826)
30. S.S. Mansy, S.P. Wu, and J.A. Cowan Iron-sulfur cluster biosynthesis: biochemical characterization of the conformational dynamics of Thermotoga maritima IscU and the relevance for cellular cluster assembly J. Biol. Chem. 279 2004 10469 10475 (Pubitemid 38372656)
31. J.L. Martin, and F.M. McMillan SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold Curr. Opin. Struct. Biol. 12 2002 783 793 (Pubitemid 36009496)
32. K. Morimoto, K. Nishio, and M. Nakai Identification of a novel prokaryotic HEAT-repeats-containing protein which interacts with a cyanobacterial IscA homolog FEBS Lett. 519 2002 123 127 (Pubitemid 34522004)
33. 1H nuclear magnetic resonance spectroscopy J. Biochem. 94 1983 893 902
34. D.J. Netz, M. Stumpfig, C. Dore, U. Mühlenhoff, A.J. Pierik, and R. Lill Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis Nat. Chem. Biol. 6 2010 758 765
35. G. Palmer, and R.H. Sands On the magnetic resonance of spinach ferredoxin J. Biol. Chem. 241 1966 253
36. J. Prilusky, C.E. Felder, T. Zeev-Ben-Mordehai, E.H. Rydberg, O. Man, J.S. Beckmann, I. Silman, and J.L. Sussman FoldIndex: a simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics 21 2005 3435 3438 (Pubitemid 41222454)
37. J. Riemer, M. Fischer, and J.M. Herrmann Oxidation-driven protein import into mitochondria: Insights and blind spots Biochim. Biophys. Acta. 1808 2011 981 989
38. N.J. Robinson, and D.R. Winge Copper metallochaperones Annu. Rev. Biochem. 79 2010 537 562
39. T.A. Rouault, and W.H. Tong Iron-sulphur cluster biogenesis and mitochondrial iron homeostasis Nat. Rev. Mol. Cell Biol. 6 2005 345 351 (Pubitemid 40516901)
40. G. Schluckebier, M. O'Gara, W. Saenger, and X. Cheng Universal catalytic domain structure of AdoMet-dependent methyltransferases J. Mol. Biol. 247 1995 16 20
41. B. Schuster-Böckler, J. Schultz, and S. Rahmann HMM Logos for visualization of protein families BMC Bioinformatics 5 2004 7
42. H. Shibayama, E. Takai, I. Matsumura, M. Kouno, E. Morii, Y. Kitamura, J. Takeda, and Y. Kanakura Identification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesis J. Exp. Med. 199 2004 581 592 (Pubitemid 38233841)
43. D.P. Sideris, and K. Tokatlidis Trapping oxidative folding intermediates during translocation to the intermembrane space of mitochondria: in vivo and in vitro studies Methods Mol. Biol. 619 2010 411 423
44. D.P. Sideris, N. Petrakis, N. Katrakili, D. Mikropoulou, A. Gallo, S. Ciofi-Baffoni, L. Banci, I. Bertini, and K. Tokatlidis A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding J. Cell Biol. 187 2009 1007 1022
45. W.H. Tong, and T.A. Rouault Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis Cell Metab. 3 2006 199 210
46. W.H. Tong, G.N. Jameson, B.H. Huynh, and T.A. Rouault Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster Proc. Natl. Acad. Sci. USA 100 2003 9762 9767 (Pubitemid 37087015)
47. L. Vernis, C. Facca, E. Delagoutte, N. Soler, R. Chanet, B. Guiard, G. Faye, and G. Baldacci A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast PLoS ONE 4 2009 e4376
48. Y. Zhang, E.R. Lyver, E. Nakamaru-Ogiso, H. Yoon, B. Amutha, D.W. Lee, E. Bi, T. Ohnishi, F. Daldal, and D. Pain Dre2, a conserved eukaryotic Fe/S cluster protein, functions in cytosolic Fe/S protein biogenesis Mol. Cell. Biol. 28 2008 5569 5582