Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization

Nature Structural and Molecular Biology

Volumn 18, Issue 3, 2011, Pages 316-322

  Fairman, James Wesley ^a,b   Wijerathna, Sanath Ranjan ^b   Ahmad, Md Faiz ^b   Xu, Hai ^b,f   Nakano, Ryo ^b   Jha, Shalini ^b   Prendergast, Jay ^b   Welin, R Martin ^c   Flodin, Susanne ^c   Roos, Annette ^c   Nordlund, Pär ^c   Li, Zongli ^d   Walz, Thomas ^d   Dealwis, Chris Godfrey ^b,e  

^a UNIVERSITY OF TENNESSEE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e CASE WESTERN RESERVE UNIVERSITY   (United States)

^f Technical R and D   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; NUCLEOTIDE; OLIGOMER; RIBONUCLEOTIDE REDUCTASE; THYMIDINE TRIPHOSPHATE;

ALLOSTERISM; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DEOXYADENINE NUCLEOTIDES; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NUCLEOTIDES; PROTEIN MULTIMERIZATION; RIBONUCLEOTIDE REDUCTASES; SACCHAROMYCES CEREVISIAE;

EID: 79952331478     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2007     Document Type: Article

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