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Bioorganic and Medicinal Chemistry

Volumn 19, Issue 24, 2011, Pages 7635-7642

Aza vinyl sulfones: Synthesis and evaluation as antiplasmodial agents

(6) Glória, Paulo M C a Gut, Jiri b Gonalves, Lídia M a Rosenthal, Philip J b Moreira, Rui a Santos, Maria M M a

a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA (Portugal)

b UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Antiplasmodial activity; Aza vinyl sulfone; Cysteine protease inhibitor; Malaria; Squaramate

Indexed keywords

ANTIMALARIAL AGENT; AZAVINYLSULFONE DERIVATIVE; CHLOROQUINE; FALCIPAIN 2; PAPAIN; UNCLASSIFIED DRUG;

ANTIMALARIAL DRUG RESISTANCE; ANTIMICROBIAL ACTIVITY; ANTIPLASMODIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ANTIMALARIALS; CYSTEINE ENDOPEPTIDASES; ERYTHROCYTES; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; SULFONES;

PLASMODIUM FALCIPARUM;

EID: 82255183034 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2011.10.018 Document Type: Article

Times cited : (23)

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