Antimalarial activity of azadipeptide nitriles

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 1, 2010, Pages 252-255

  Löser, Reik ^a,c   Gut, Jiri ^b   Rosenthal, Philip J ^b   Frizler, Maxim ^c   Gütschow, Michael ^c   Andrews, Katherine T ^d,e  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF BONN   (Germany)

^d GRIFFITH UNIVERSITY   (Australia)

^e QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Azadipeptide nitriles; Cysteine protease inhibitors; Falcipains; Malaria; P. falciparum

Indexed keywords

CHLOROQUINE; CYSTEINE PROTEINASE; FALCIPAIN 2; FALCIPAIN 3; NITRILE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ERYTHROCYTE; IC 50; MALARIA FALCIPARUM; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; AZA COMPOUNDS; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; NITRILES; PLASMODIUM FALCIPARUM;

PLASMODIUM FALCIPARUM;

EID: 72049088495     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.122     Document Type: Article

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