Acute liver failure - A life-threatening disease;Übersichtsarbeit - Akutes leberversagen

Deutsches Arzteblatt

Volumn 108, Issue 42, 2011, Pages 714-720

  Canbay, Ali ^a   Tacke, Frank ^b   Hadem, Johannes ^c   Trautwein, Christian ^b   Gerken, Guido ^a   Manns, Michael P ^c  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ACETYLCYSTEINE; ACICLOVIR; ANABOLIC AGENT; ENTECAVIR; HALOTHANE; ISONIAZID; LAMIVUDINE; PARACETAMOL; PHENPROCOUMON; PREDNISOLONE; SILIBININ; TENOFOVIR; TETRACYCLINE; TOXIC SUBSTANCE;

ACUTE KIDNEY FAILURE; ACUTE LIVER FAILURE; ALPHA 1 ANTITRYPSIN DEFICIENCY; AUTOIMMUNE HEPATITIS; BUDD CHIARI SYNDROME; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DRUG INTOXICATION; DRUG MEGADOSE; EPSTEIN BARR VIRUS; FATTY LIVER; GERMANY; GRAFT VERSUS HOST REACTION; HELLP SYNDROME; HEPATIC ENCEPHALOPATHY; HEPATITIS B; HUMAN; INTENSIVE CARE; LIVER FUNCTION; LIVER TRANSPLANTATION; MORTALITY; PATHOPHYSIOLOGY; PROGNOSIS; PUBLIC-PRIVATE PARTNERSHIP; REVIEW; SHOCK; VEIN OCCLUSION; VIRUS HEPATITIS; WILSON DISEASE;

GERMANY; HUMANS; INTERNATIONALITY; LIVER FAILURE, ACUTE; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION;

EID: 82255182298     PISSN: 00121207     EISSN: 01722107     Source Type: Journal    
DOI: 10.3238/arztebl.2011.0714     Document Type: Review

References (49)

1. Trey C, Davidson CS: The management of fulminant hepatic failure. Prog Liver Dis 1970; 3: 282-98.
2. Lee WM, Squires RH, Nyberg SL, Doo E, Hoofnagle JH: Acute liver failure: Summary of a workshop. Hepatology 2008; 47: 1401-15. (Pubitemid 351547926)
3. O'Grady JG, Alexander GJ, Hayllar KM, Williams R: Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 1989; 97: 439-45. (Pubitemid 19192181)
4. Bernal W, Wendon J: Liver transplantation in adults with acute liver failure. J Hepatol 2004; 40: 192-7. (Pubitemid 38115821)
5. Wei G, Bergquist A, Broomé U, et al.: Acute liver failure in Sweden: etiology and outcome. J Intern Med 2007; 262: 393-401. (Pubitemid 47246972)
6. Escorsell A, Mas A, de la Mata M: Acute liver failure in Spain: analysis of 267 cases. Liver Transpl 2007; 13: 1389-95. (Pubitemid 47629571)
7. Hadem J, Stiefel P, Bahr MJ, et al.: Prognostic implications of lactate, bilirubin, and etiology in German patients with acute liver failure. Clin Gastroenterol Hepatol 2008; 6: 339-45. (Pubitemid 351318381)
8. Canbay A, Jochum C, Bechmann LP, et al.: Acute liver failure in a metropolitan area in Germany: a retrospective study (2002-2008). Z Gastroenterol 2009; 47: 807-13.
9. Schimanski CC, Burg J, Möhler M, et al.: Phenprocoumon-induced liver disease ranges from mild acute hepatitis to (sub-) acute liver failure. J Hepatol 2004; 41: 67-74. (Pubitemid 39005155)
10. Schmidt LE, Dalhoff K: Concomitant overdosing of other drugs in patients with paracetamol poisoning. Br J Clin Pharmacol 2002; 53: 535-41. (Pubitemid 34526505)
11. Krähenbuhl S, Brauchli Y, Kummer O, et al.: Acute liver failure in two patients with regular alcohol consumption ingesting paracetamol at therapeutic dosage. Digestion 2007; 75: 232-7. (Pubitemid 350202474)
12. Strnad P, Zhou Q, Hanada S, et al.: Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations. Gastroenterology 2010; 139: 828-35.
13. Rantala M, van de Laar MJW: Surveillance and epidemiology of hepatitis B and C in Europe - a review. Euro Surveill [Internet] 2008 [cited 2011]; 13. available from: www.ncbi.nlm.nih.gov/pub med/18761967
14. Cornberg M, Protzer U, Dollinger MM, et al.: Prophylaxis, diagnosis and therapy of hepatitis B virus (HBV) infection: the German guidelines for the management of HBV infection. Z Gastroenterol 2007; 45: 1281-328.
15. Eisenbach C, Sieg O, Stremmel W, Encke J, Merle U: Diagnostic criteria for acute liver failure due to Wilson disease. World J Gastroenterol 2007; 13: 1711-4. (Pubitemid 46711343)
16. Bechmann LP, Jochum C, Kocabayoglu P, et al.: Cytokeratin 18-based modification of the MELD score improves prediction of spontaneous survival after acute liver injury. J Hepatol [Internet] 2010 [cited 2010]; available from: www.ncbi.nlm.nih.gov/pubmed/20630612
17. Tacke F, Luedde T, Trautwein C: Inflammatory pathways in liver homeostasis and liver injury. Clin Rev Allergy Immunol 2009; 36: 4-12.
18. Jalan R, Hayes PC: Hepatic encephalopathy and ascites. Lancet 1997; 350: 1309-15. (Pubitemid 28036648)
19. Albrecht J, Zieliñska M, Norenberg MD: Glutamine as a mediator of ammonia neurotoxicity: A critical appraisal. Biochem Pharmacol 2010; 80: 1303-8.
20. Bernal W, Auzinger G, Sizer E, Wendon J: Intensive care management of acute liver failure. Semin Liver Dis 2008; 28: 188-200. (Pubitemid 351632958)
21. Honore PM, Jamez J, Wauthier M, et al.: Prospective evaluation of short-term, high-volume isovolemic hemofiltration on the hemodynamic course and outcome in patients with intractable circulatory failure resulting from septic shock. Crit Care Med 2000; 28: 3581-7.
22. Bernal W, Cross TJS, Auzinger G, et al.: Outcome after wait-listing for emergency liver transplantation in acute liver failure: a single centre experience. J Hepatol 2009; 50: 306-13.
23. Kamath PS, Kim WR: The model for end-stage liver disease (MELD). Hepatology 2007; 45: 797-805. (Pubitemid 46450631)
24. Ostapowicz G, Fontana RJ, Schiødt FV, et al.: Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 2002; 137: 947-54. (Pubitemid 35440240)
25. Heemann U, Treichel U, Loock J, et al.: Albumin dialysis in cirrhosis with superimposed acute liver injury: a prospective, controlled study. Hepatology 2002; 36: 949-58.
26. O'Grady JG, Schalm SW, Williams R: Acute liver failure: redefining the syndromes. Lancet 1993; 342: 273-5.
27. Canbay A, Gerken G: Specific therapy in acute liver failure. Med Klin 2006; 101(Suppl 1): 111-4.
28. Larsen FS, Kirkegaard P, Rasmussen A, Hansen BA: The Danish liver transplantation program and patients with serious acetaminophen intoxication. Transplant Proc 1995; 27: 3519-20.
29. Leifeld L, Merk P, Schmitz V, et al.: Course and therapy of acute liver failure. Eur J Med Res 2008; 13: 87-91.
30. Lee WM: Acetaminophen and the U.S. Acute Liver Failure Study Group: lowering the risks of hepatic failure. Hepatology 2004; 40: 6-9.
31. Acuña G, Foernzler D, Leong D, et al.: Pharmacogenetic analysis of adverse drug effect reveals genetic variant for susceptibility to liver toxicity. Pharmacogenomics J 2002; 2: 327-34.
32. Jochum C, Gieseler RK, Gawlista I, et al.: Hepatitis B-associated acute liver failure: immediate treatment with entecavir inhibits hepatitis B virus replication and potentially its sequelae. Digestion 2009; 80: 235-40.
33. Tillmann HL, Hadem J, Leifeld L, et al.: Safety and efficacy of lamivudine in patients with severe acute or fulminant hepatitis B, a multicenter experience. J Viral Hepat 2006; 13: 256-63.
34. Teschke R: Hepatotoxicity by drugs and dietary supplements: safety perspectives on clinical and regulatory issues. Ann Hepatol 2009; 8: 184-95.
35. Wasmuth J, Fischer H, Sauerbruch T, Dumoulin FL: Fatal acute liver failure due to reactivation of hepatitis B following treatment with fludarabine/cyclophosphamide/rituximab for low grade non- Hodgkin's lymphoma. Eur J Med Res 2008; 13: 483-6.
36. Häussinger D, Görg B: Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity. Curr Opin Clin Nutr Metab Care. 2010; 13: 87-92.
37. Bernuau J, Benhamou JP: Classifying acute liver failure. Lancet 1993; 342: 252-3.
38. Auzinger G, Wendon J: Intensive care management of acute liver failure. Curr Opin Crit Care 2008; 14: 179-88.
39. Eefsen M, Dethloff T, Frederiksen H, Hauerberg J, Hansen BA, Larsen FS: Comparison of terlipressin and noradrenalin on cerebral perfusion, intracranial pressure and cerebral extracellular concentrations of lactate and pyruvate in patients with acute liver failure in need of inotropic support. J Hepatol 2007; 47: 381-6.
40. Bismuth H, Samuel D, Castaing D, Williams R, Pereira SP: Liver transplantation in Europe for patients with acute liver failure. Semin Liver Dis 1996; 16: 415-25.
41. Dubbeld J, Hoekstra H, Farid W, et al.: Similar liver transplantation survival with selected cardiac death donors and brain death donors. Br J Surg 2010; 97: 744-53.
42. Jay C, Skaro A, Ladner D, et al.: A comprehensive risk assessment of mortality following donation after cardiac death liver transplant - an analysis of the National Registry. J Hepatol [Internet] 2011 [cited 2011]; available from: www.ncbi.nlm.nih.gov/ pubmed/21338639
43. Heidenhain C, Pratschke J, Puhl G, et al.: Incidence of and risk factors for ischemic-type biliary lesions following orthotopic liver transplantation. Transpl Int 2010; 23: 14-22.
44. Bernuau J, Goudeau A, Poynard T, et al.: Multivariate analysis of prognostic factors in fulminant hepatitis B. Hepatology 1986; 6: 648-51.
45. Schmidt LE, Larsen FS: Blood lactate as a prognostic marker in acetaminophen-induced acute liver failure. Hepatology 2003; 37: 1199-1201.
46. Canbay A, Chen S, Gieseler RK, et al.: Overweight patients are more susceptible for acute liver failure. Hepatogastroenterology 2005; 52: 1516-20.
47. Rutherford A, Davern T, Hay JE, et al.: Influence of high body mass index on outcome in acute liver failure. Clin Gastroenterol Hepatol 2006; 4: 1544-9.
48. Samuel D, Ichai P: Prognosis indicator in acute liver failure: Is there a place for cell death markers? J Hepatol 2010; 53: 593-5.
49. Koch A, Trautwein C: N-acetylcysteine on its way to a broader application in patients with acute liver failure. Hepatology 2010; 51: 338-40.