Influence of High Body Mass Index on Outcome in Acute Liver Failure

Clinical Gastroenterology and Hepatology

Volumn 4, Issue 12, 2006, Pages 1544-1549

  Rutherford, Anna ^a   Davern, Tim ^b   Hay, J Eileen ^c   Murray, Natalie G ^d   Hassanein, Tarek ^e   Lee, William M ^f   Chung, Raymond T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MAYO CLINIC   (United States)

^d BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BODY MASS; CONTROLLED STUDY; DIABETES MELLITUS; FEMALE; HEALTH SURVEY; HUMAN; INCIDENCE; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OBESITY; OUTCOME ASSESSMENT; POPULATION; PREVALENCE; STATISTICAL SIGNIFICANCE;

ADULT; BODY MASS INDEX; DIABETES MELLITUS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; MALE; OBESITY; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; UNITED STATES;

EID: 33845370467     PISSN: 15423565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cgh.2006.07.014     Document Type: Article

References (24)

1. Gupte P., Amarapurkar D., Agal S., et al. Non-alcoholic steatohepatitis in type 2 diabetes mellitus. J Gastroenterol Hepatol 19 (2004) 854-858
2. Silverman J.F., Pories W.T., and Caro J.F. Liver pathology in diabetes mellitus and morbid obesity: clinical, pathological and biochemical considerations. Pathol Annu 24 (1989) 275-302
3. Angulo P., Keach J.C., Batts K.P., et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 30 (1999) 1356-1362
4. Day C.P. NASH-related liver failure: one hit too many?. Gastroenterology 97 (2002) 1872-1874
5. Leclercq I.A., Field J., and Farrell G.C. Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury. Gastroenterology 124 (2003) 1451-1464
6. Reid A.E. Nonalcoholic steatohepatitis. Gastroenterology 121 (2001) 710-723
7. El-Serag H.B., and Everhart J.E. Diabetes increases the risk of acute hepatic failure. Gastroenterology 122 (2002) 1822-1828
8. Davern T.J., Schilsky M.L., Hynan L.S., et al. Prevalence of diabetes mellitus in not increased in acute liver failure. Hepatology 40 (2004) 499A
9. Caldwell S.H., and Hespenheide E.E. Subacute liver failure in obese women. Am J Gastroenterol 97 (2002) 2058-2062
10. Charlson M.E., Pompei P., Ales K.L., et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 5 (1987) 373-383
11. Wai C.T., Fontana R.J., Polson J., et al. Clinical outcome and virologic characteristics of hepatitis B-related acute liver failure in the United States. J Viral Hepat 12 (2005) 192-198
12. Schiodt F., Rossaro L., Stravitz R.T., et al. Gc-globulin and prognosis in acute liver failure. Liver Transpl 11 (2005) 1223-1227
13. Ostapowicz G., Fontana R.J., Schiodt F.V., et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 137 (2002) 947-954
14. Wiesner R.H. MELD/PELD and the allocation of deceased donor livers for status 1 recipients with acute fulminant hepatic failure, primary nonfunction, hepatic artery thrombosis, and acute Wilson's disease. Liver Transpl 10 Suppl 2 (2004) S17-S22
15. Hedley A.A., Ogden C.L., Johnson C.L., et al. Prevalence of overweight and obesity among US children, adolescents and adults, 1999-2002. JAMA 291 (2004) 2847-2850
16. Canbay A., Chen S.Y., Gieseler R.K., et al. Overweight patients are more susceptible for acute liver failure. Hepatogastroenterology 65 (2005) 1516-1520
17. Kanda T., Yokosuka O., Hiraide A., et al. Prevalence of obesity in patients with acute hepatitis: is severe obesity a risk factor for fulminant hepatitis in Japan?. Hepatogastroeneterology 52 (2005) 180-182
18. Lee W.H., Kramer W.G., and Granville G.E. The effect of obesity on acetaminophen pharmacokinetics in man. J Clin Pharmacol 21 (1981) 284-287
19. Wong B.K., U S.W., and Corcoran G.B. An overfed rat model that reproduces acetaminophen disposition in obese humans. Drug Metab Dispos 14 (1986) 674-679
20. Abernethy D.R., Greenblatt D.J., Divoll M., et al. Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen. J Lab Clin Med 101 (1983) 873-880
21. Chaudhary I.P., Tuntaterdtum S., McNamara P.J., et al. Effect of genetic obesity and phenobarbital treatment on the hepatic conjugation pathways. J Pharmacol Exp Ther 265 (1993) 1333-1338
22. Rustgi V.K., Marino G., Rustgi S., et al. Impact of body mass index on graft failure and overall survival following liver transplant. Clin Transplant 18 (2004) 634-637
23. Nair S., Verma S., and Thuluvath P.J. Obesity and its effect on survival in patients undergoing orthotopic liver transplantation in the United States. Hepatology 35 (2002) 105-109
24. Pelletier S.J., Maraschio M.A., Schaubel D.E., et al. Survival benefit of kidney and liver transplantation for obese patients on the waiting list. Clin Transpl (2003) 77-88